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Prioritize drug targets from a ranked gene list (e.g., scRNA-seq DE output) by orchestrating parallel API queries against UniProt, OpenTargets (with integrated DepMap CRISPR essentiality + gnomAD constraint), PubMed, the Human Protein Atlas (HPA), and ChEMBL tool compounds, then re-ranking by a composite score combining protein localization, druggability, disease genetics, tissue specificity (safety), focus-cell-type expression, CRISPR essentiality, LoF safety constraint, and research maturity. Use whenever the user wants to filter, triage, prioritize, or "do due diligence" on a list of candidate genes for drug discovery, especially after a DE / DEG analysis when they say things like "which of these should I follow up on", "filter for druggable targets", "make a target dossier", "rank these for tractability", "annotate these genes for druggability", or "build a target report". Trigger even when the user says just "filter these candidate genes" or hands over a CSV from a DE pipeline.

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Win #1 Product of the Day on Product Hunt. Completely reverse-engineered from 30x daily winner and 3x weekly winner campaigns — ranking algorithm decoded, launch timing optimized, hunter selection guide, community engagement approach, and post-launch momentum playbook. Use this if you're: (1) already read PH launch guides but still can't break into Top 5 and need algorithm-level deep optimization, (2) targeting Daily #1 and 5,000+ sign-ups with a proven 30+ case validated approach, or (3) an investor/accelerator coaching portfolio companies on PH launches. What's inside: PH ranking algorithm decoded: weighted factors for first 3 hours, 24 hours, and weekly ranking · Pre-launch preparation: gallery optimization, product URL selection, tagline refinement (≤60 chars) · Launch timing optimization: exact PST launch windows + scheduling guide · Community engagement KPIs: upvote targets, comment response time, maker comment strategy · Platform compliance guide: understanding PH's quality signals and organic growth · Post-launch 72-hour plan: maintaining momentum, conditions for Weekly #1 · Case studies: 3 different categories (AI Tool, App, SaaS) dissected Expected outcomes: Product Hunt Daily #1 ranking · strong community engagement on launch day · 3,000–10,000+ sign-ups (depending on product-market fit) 🇨🇳 Product Hunt 打榜完整攻略 | 🇯🇵 Product Hunt ローンチガイド | 🇰🇷 Product Hunt 런칭 가이드 Keywords: Product Hunt #1, Product Hunt launch strategy, PH ranking algorithm, PH #1 daily winner, Product Hunt tips, product launch, startup launch, ranking optimization, PH gallery optimization, Community engagement strategy, maker community engagement, product strategy, launch tactics, how to win Product Hunt, product hunt best practices

每日 SEO/GEO 巡逻（2026-06-24 标准）。覆盖：SERP 关键词排名追踪（DataForSEO / volume 300-1000 / KD 5-35）、 Google 索引数统计、llms.txt 可达性、GA4 tag 部署检测及 AI 来源 channel 配置、 PH canonical 合并修复、社媒关键词雪崩救援（title 含 best/free/top/guide+年份、内链注入 ≤2-3/段、 主动 cite 竞品外链）。当用户说"跑 SEO 日报"、"检查排名"、"某关键词掉了"、"修 canonical"、"加内链"时调用。

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Returns the universal governance spec for swarm team runs — hard rules, briefing templates, gate presentation contract, launch mechanics, and pulse setup. The canonical source: invoked by launch.md at Step 1 and by user-authored shortcut commands that cannot read launch.md directly. Per-gate constants live in swarm:gate-presentation.

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Reviews iOS animation code for correctness, performance, accessibility, and Apple API best practices. Use when reviewing .swift files containing animation code — withAnimation, .animation(), PhaseAnimator, KeyframeAnimator, matchedGeometryEffect, navigationTransition, CABasicAnimation, CASpringAnimation, UIViewPropertyAnimator, UIDynamicAnimator, symbolEffect, scrollTransition, contentTransition, or custom Transition conformances.

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Use when the user wants a cited, structured read of local documents and project knowledge. Triggers on: "analyze these docs", "scan my project for context", "read the docs folder", "summarize what's in .beagle/concepts/", "extract context from docs/", "what's in this folder", "go read everything in X and tell me what's there". Also invoked programmatically by other beagle skills (prfaq-beagle Ignition, brainstorm-beagle reference points, strategy-interview context grounding) via the companion contract. Does NOT trigger on codebase lookups ("find this function", "search the repo"), web research (use web-research), LLM-as-judge evaluation (use llm-judge), or document editing (use humanize-beagle). Produces a written scan plan, parallel-subagent findings, and a cited synthesis report on disk — never inline prose, never unsourced claims.

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Run a Meta-Harness-style optimization loop NATIVELY — automatically search over the scaffolding around a FIXED base model (memory, retrieval, context construction, prompt templates, summarization, tool-selection logic) by proposing candidate variants, scoring each on a cheap deterministic eval, and keeping a Pareto frontier of quality vs cost — using native Agent / Workflow / loop tools instead of a standalone Python harness. Use this whenever the user wants to optimize, evolve, tune, distill, or search over a harness, scaffold, prompt system, memory or retrieval policy, context-assembly code, or summarizer while keeping the model fixed; whenever they mention Meta-Harness, harness optimization, scaffold evolution, automatic prompt/memory optimization, an evolutionary or Pareto search over candidate implementations, or "make the harness/agent better without retraining"; and whenever the gain must come from the code AROUND the model rather than the model weights. Reproduces the Meta-Harness paper's method natively, with no claude_wrapper.py and no metered solver API.

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Reference for the diagnostics pipeline (ripdpi-monitor-engine/ripdpi-diagnostics-* and core/diagnostics). Use when changing ScanRequest/ScanReport, ProbeTask families, probe scheduling, the catalog, or the wire contract. Techniques: desync-engine.

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Act as a project-management copilot (PM/PMO) for the delivery loop: charters, plans and schedules, estimates, risk registers, status reports, scope changes, stakeholder communication, meeting actions, lessons learned, and portfolio roll-ups, in a per-project `_project/` workspace. Use whenever the user wants to start, plan, track, rescue, or report on a project: "kick off this project", "make a project plan / timeline / WBS", "what date can I commit to", "build a risk register", "run a pre-mortem", "write the weekly status report", "the deadline slipped, what now", "turn this meeting into action items", "review my project portfolio", in any language ("quản lý dự án", "gestion de projet", "プロジェクト管理", "项目管理"), even when they never say "project management". Also use whenever a `_project/` directory exists and the user asks about schedule, deadline, risk, status, scope, budget, or stakeholders. Not for what to build (product-manager) or company-level bets (strategy-board).

Run human-to-agent migration - audit which roles can be agent-assisted or replaced, design the transition playbook, and manage the offboarding of displaced roles. Use when asked to "which roles can agents replace", "how do we transition to AI-first ops", or "build our agent migration plan".

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Expert guide for defending AI applications against prompt injection, jailbreak attacks, indirect injection via tool outputs, and data exfiltration through tool calls — input sanitization, output filtering, canary token detection, and layered defense architecture / Panduan ahli pertahanan aplikasi AI terhadap prompt injection, serangan jailbreak, injeksi tidak langsung via output tool, dan eksfiltrasi data melalui tool calls — sanitasi input, filtering output, deteksi canary token, dan arsitektur pertahanan berlapis.

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Run Ultimate Bug Scanner (UBS) for code review. Use when reviewing code, checking for bugs, scanning for security issues, validating AI-generated code, or pre-commit quality checks.

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Run a daily job search and auto-apply session for the candidate in profile/profile.md. Use when the user runs /seekter-run or asks to start applications, search for jobs, run today's scan, or apply to postings.

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Use when you have captured session evidence — session-retro / session- observatory-live traces in .planning/patterns/, tool logs, correction records — and want to induce a reusable skill from it. Segments the traces into candidate skill units (an LLM judgment, not a deterministic parse) and decomposes each candidate into a four-part structured spec: workflow structure, execution semantics, and runtime attachments (verification, safety, rollback, state). It emits a spec object, NOT a finished SKILL.md, and hands that spec to skill-forge. It sits between skill-integration (upstream frequency detector) and skill-forge (downstream author). Backed by Agent-Trace-to-Skill Induction (arxiv 2606.06893v1). Triggers on inducing a skill from captured traces, turning a repeated pattern into a skill spec, and preparing evidence for skill-forge.

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Scans Cosmos SDK blockchains for 9 consensus-critical vulnerabilities including non-determinism, incorrect signers, ABCI panics, and rounding errors. Use when auditing Cosmos chains or CosmWasm contracts. (project, gitignored)

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Analyze code changes for security vulnerabilities using LLM reasoning and threat model patterns. Use for PR reviews, pre-commit checks, or branch comparisons.

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Scans Cairo/StarkNet smart contracts for 6 critical vulnerabilities including felt252 arithmetic overflow, L1-L2 messaging issues, address conversion problems, and signature replay. Use when auditing StarkNet projects. (project, gitignored)

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Scans Algorand smart contracts for 11 common vulnerabilities including rekeying attacks, unchecked transaction fees, missing field validations, and access control issues. Use when auditing Algorand projects (TEAL/PyTeal). (project, gitignored)

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Use this skill when the user wants to discover, define, or refine their product's aesthetic identity. Triggers on "what should this feel like?", "help me figure out the vibe", "something feels off visually", "I want it to feel like [X]", "define the visual language", or when a project has no established design direction. This is the art director skill - it helps users articulate something they can feel but can't name. Also handles quick cohesion checks when the orchestrator needs one during cycle planning.

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Use when creating or updating the project skill discovery config — generates or regenerates .dh/skill_discovery.yaml by scanning the repo to infer tech stack, inventorying installed skills via npx skills list, loading candidate skill content before suggesting, and writing a config-driven skill injection file. Triggers on /dh:setup-skill-discovery invocations and programmatic --auto calls from add-new-feature Phase 3.

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Use when a set of candidate Skills or app capabilities is technically valid but still needs to become a clear, useful ChatGPT/Codex Plugin that people can understand, discover, and invoke for real work.

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OCRs scanned or image-only corpora with vision-language models in three phases. Evaluate selects a system by measured CER or WER against stratified human ground truth. Run builds the production pipeline. Clean corrects raw OCR with LLM and rule-based passes, quality diagnostics, and span-level provenance. Use when choosing an OCR model for a corpus, measuring OCR accuracy, transcribing scans at scale, or correcting raw OCR. Born-digital documents with text layers go to doc-to-markdown.

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Scan your Claude Code configuration (.claude/ directory) for security vulnerabilities, misconfigurations, and injection risks using AgentShield. Checks CLAUDE.md, settings.json, MCP servers, hooks, and agent definitions.

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Assesses agent capabilities by analyzing agent files and determining what tasks they can handle. Use when you need to evaluate if an existing agent can handle a task or if a new agent is needed. Reviews agent descriptions, skills, and workflows to determine capability match.

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