1,236 件 ・ 関連度順
概要と使いどころ
Build publication-quality figures in R with ggplot2 using the grammar of graphics (data + aesthetics + geometries + scales + facets + themes) with CVD-safe palettes, cairo_pdf TrueType embedding, programmatic aes via tidy evaluation, and the theme_classic publication baseline. Use when producing static figures in R for papers, presentations, or reports.
日本語の概要は準備中です。原文の説明を表示しています。
Detect positive (diversifying / episodic / pervasive) selection using codon dN/dS frameworks. Implements PAML codeml site models (M0/M1a/M2a/M7/M8/M8a), branch models, branch-site model A (Zhang 2005), and HyPhy methods (BUSTED, BUSTED-S, BUSTED-MH, BUSTED-PH, MEME, FEL, FUBAR, aBSREL, SLAC, RELAX, GARD, FUBAR-MH). Includes McDonald-Kreitman framework (asymptotic alpha, impMKT, polyDFE, DFE-alpha, GRAPES) for within-species + divergence inference, RERconverge for trait-correlated rate shifts, CSUBST for convergent substitution, and PhyloAcc for accelerated noncoding evolution. Use when testing adaptive evolution at codons, branches, or full gene; running GARD recombination pre-screen; controlling alignment-error and gBGC false positives; reconciling PAML vs HyPhy results; or performing genome-scale selection scans.
日本語の概要は準備中です。原文の説明を表示しています。
Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.
日本語の概要は準備中です。原文の説明を表示しています。
Project gene annotations across genomes using TOGA (Kirilenko 2023 whole-genome-alignment chain-based projection with intactness classification), CESAR 2.0 (Sharma & Hiller 2017 codon-aware exon projection), LiftOff (Shumate & Salzberg 2020 reference-based annotation transfer), Liftover (UCSC), GeMoMa (Keilwagen 2019 evidence-based projection), and Comparative Annotation Toolkit (CAT). Use when transferring annotations from a well-annotated reference to query genome(s), classifying gene-loss vs gene-intact across many genomes at scale, building Zoonomia-style comparative annotations across hundreds of mammals or birds (Kirilenko 2023), detecting pseudogenization, projecting alternative isoforms, or selecting between WGA-anchored (TOGA) vs ortholog-based (LiftOff) annotation transfer strategies.
日本語の概要は準備中です。原文の説明を表示しています。
Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.
日本語の概要は準備中です。原文の説明を表示しています。
Delegating work down to subagents: briefs, report statuses, independent review. Use when writing an implementer or verifier brief, dispatching a subagent to build, fix, or verify work you own, or a subagent reports DONE, blocked, or concerns. NOT for campaign-scale doctrine (use campaign-pattern).
日本語の概要は準備中です。原文の説明を表示しています。
When the user wants to audit, review, or diagnose SEO issues on their site. Also use when the user mentions "SEO audit," "technical SEO," "why am I not ranking," "SEO issues," "on-page SEO," "meta tags review," or "SEO health check." For building pages at scale to target keywords, see programmatic-seo. For adding structured data, see schema-markup.
日本語の概要は準備中です。原文の説明を表示しています。
React composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.
日本語の概要は準備中です。原文の説明を表示しています。
Elite frontend image-direction skill for generating premium, conversion-aware website design references. CRITICAL OUTPUT RULE — generate ONE separate horizontal image FOR EVERY section. A landing page with 8 sections produces 8 images. Never compress multiple sections into one image. Enforces composition variety (not always left-text / right-image), background-image freedom, varied CTAs, varied hero scales (giant / mid / mini minimalist), narrative concept spine, second-read moments, and a single consistent palette across all images. Optimized for landing pages, marketing sites, and product comps that developers or coding models can accurately recreate.
日本語の概要は準備中です。原文の説明を表示しています。
Raw mechanical interfaces fusing Swiss typographic print with military terminal aesthetics. Rigid grids, extreme type scale contrast, utilitarian color, analog degradation effects. For data-heavy dashboards, portfolios, or editorial sites that need to feel like declassified blueprints.
日本語の概要は準備中です。原文の説明を表示しています。
Convex is the backend agents get right on the first try: an all-TypeScript reactive platform where the database, server functions, scheduling, file storage, auth, and realtime sync are one type-safe system, every function is a transaction, and `tsc` catches most mistakes before deploy. Ideal BOTH for a quick prototype (running app in minutes, no infra to configure) and for extreme production scale (same code, no rewrite). Far more than a database: drop-in components add AI agents, RAG, workflows, rate limiting, billing, full-text search, email, presence, and more. Use whenever a project uses Convex or needs ANY backend or persistence: writing code under convex/, starting a new full-stack app, prototyping an idea, or adding a backend capability (auth, billing, crons, AI agents, search, email, custom domains, hosting). Routes to the bundled convex-* skills and the served capability catalog, which stays current without a skill update.
日本語の概要は準備中です。原文の説明を表示しています。
Audit and optimize an existing Convex app: security, scale, upgrades, observability.
日本語の概要は準備中です。原文の説明を表示しています。
Optimize Bazel builds for large-scale monorepos. Use when configuring Bazel, implementing remote execution, or optimizing build performance for enterprise codebases.
日本語の概要は準備中です。原文の説明を表示しています。
Validates animation durations, enforces typography scale, checks component accessibility, and prevents layout anti-patterns in Tailwind CSS projects. Use when building UI components, reviewing CSS utilities, styling React views, or enforcing design consistency.
日本語の概要は準備中です。原文の説明を表示しています。
Run Playwright tests at scale with cloud-hosted browsers and integrated Azure portal reporting.
日本語の概要は準備中です。原文の説明を表示しています。
Azure Batch SDK for Java. Run large-scale parallel and HPC batch jobs with pools, jobs, tasks, and compute nodes.
日本語の概要は準備中です。原文の説明を表示しています。
Azure AI Document Translation SDK for batch translation of documents with format preservation. Use for translating Word, PDF, Excel, PowerPoint, and other document formats at scale.
日本語の概要は準備中です。原文の説明を表示しています。
Create, iterate, and scale paid ad creative for Google Ads, Meta, LinkedIn, TikTok, and similar platforms. Use when generating headlines, descriptions, primary text, or large sets of ad variations for testing and performance optimization.
日本語の概要は準備中です。原文の説明を表示しています。
Reserved and on-demand GPU cloud instances for ML training and inference. Use when you need dedicated GPU instances with simple SSH access, persistent filesystems, or high-performance multi-node clusters for large-scale training.
日本語の概要は準備中です。原文の説明を表示しています。
High-level PyTorch framework with Trainer class, automatic distributed training (DDP/FSDP/DeepSpeed), callbacks system, and minimal boilerplate. Scales from laptop to supercomputer with same code. Use when you want clean training loops with built-in best practices.
日本語の概要は準備中です。原文の説明を表示しています。
GPU-accelerated data curation for LLM training. Supports text/image/video/audio. Features fuzzy deduplication (16× faster), quality filtering (30+ heuristics), semantic deduplication, PII redaction, NSFW detection. Scales across GPUs with RAPIDS. Use for preparing high-quality training datasets, cleaning web data, or deduplicating large corpora.
日本語の概要は準備中です。原文の説明を表示しています。
Provides PyTorch-native distributed LLM pretraining using torchtitan with 4D parallelism (FSDP2, TP, PP, CP). Use when pretraining Llama 3.1, DeepSeek V3, or custom models at scale from 8 to 512+ GPUs with Float8, torch.compile, and distributed checkpointing.
日本語の概要は準備中です。原文の説明を表示しています。
Managed vector database for production AI applications. Fully managed, auto-scaling, with hybrid search (dense + sparse), metadata filtering, and namespaces. Low latency (<100ms p95). Use for production RAG, recommendation systems, or semantic search at scale. Best for serverless, managed infrastructure.
日本語の概要は準備中です。原文の説明を表示しています。
Facebook's library for efficient similarity search and clustering of dense vectors. Supports billions of vectors, GPU acceleration, and various index types (Flat, IVF, HNSW). Use for fast k-NN search, large-scale vector retrieval, or when you need pure similarity search without metadata. Best for high-performance applications.
日本語の概要は準備中です。原文の説明を表示しています。