Automatically convert uploaded drug application documents (Word/PDF) into XML skeleton structure compliant with eCTD 4.0/3.2.2 specifications.
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概要と使いどころ
Automatically convert uploaded drug application documents (Word/PDF) into XML skeleton structure compliant with eCTD 4.0/3.2.2 specifications.
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Adapt scientific abstracts to conference-specific word limits, section rules, and formatting constraints; use when reshaping an existing abstract for submission.
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Generates structured biomedical outlines for review articles, discussion sections, and thesis proposals. Use when a user provides biomedical keywords, results/discussion text, or a proposal title plus background and needs a directly usable academic writing scaffold.
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EndNote reference formatting workflow — converts [PMID: xxxx] markers in Markdown manuscripts to Word (.docx) using EndNote CWYW-recognized {Author, Year, Title} placeholders, while generating .ris files for automatic import into the local EndNote library. Users click "Update ...
日本語の概要は準備中です。原文の説明を表示しています。
Precision editing tool that reduces abstract word count through intelligent compression techniques, maintaining scientific rigor while meeting strict journal and conference requirements.
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Transform lengthy academic papers into concise, structured 250-word abstracts.
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Refines broad, vague, or aspirational biomedical research objectives into clear, bounded, measurable, executable, and downstream-ready study objective statements. Always use this skill when a user has a general aim such as “explore a mechanism,” “study prognosis,” “investigate biomarkers,” or “look at treatment response,” but the objective is still too broad, non-operational, or too ambiguous to support protocol framing, design selection, analysis planning, or hypothesis design. Never assume that polished wording alone means the objective is actionable. Focus first on objective type, missing operational elements, scope discipline, and downstream-ready formulation.
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Acknowledges limitations in sample, design, measurement, and validation in a professional way that improves credibility without undermining the whole paper. Use when writing the limitations paragraph of a Discussion section, preparing a grant risk assessment, responding to reviewers about study weaknesses, or framing scope boundaries for a paper. Also triggers on "write my limitations", "how should I address the limitation of", "reviewer said my sample is too small", or "help me word this limitation".
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Use when selecting predictive genes or other molecular features from bulk expression matrices for binary case-vs-control classification with elastic net logistic regression, including coefficient path and cross-validation plots. Trigger keywords: elastic net, glmnet, feature selection, binary classification, lambda.min, lambda.1se. NOT for: survival/Cox modeling, multiclass outcomes, single-cell data, or non-expression tables.
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Use this skill to compute ESTIMATE immune-related microenvironment scores from a bulk expression matrix, generate an ESTIMATE score heatmap, and optionally generate group-wise ESTIMATE score boxplots plus significance tables when a sample group file is supplied. Trigger keywords: ESTIMATE, immune score, stromal score, tumor microenvironment score. NOT for: immune cell deconvolution, single-cell analysis, differential expression, clinical diagnosis.
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Calibrates manuscript claim strength so wording matches the actual evidence level, study design, and validation status.
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Builds prioritized manuscript revision plans for major or minor revisions by separating comments that require experiments, analyses, clarification, restructuring, or wording changes.
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Use this skill to run GSVA or ssGSEA pathway-level differential analysis from a bulk expression matrix and a sample group file, then generate a heatmap from the saved GSVA result object. Trigger keywords: GSVA, ssGSEA, pathway enrichment, KEGG pathway analysis, MSigDB. NOT for: gene-level differential expression, single-cell analysis, methylation analysis, clinical diagnosis.
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Use when building a sample-level hierarchical clustering dendrogram from a bulk expression matrix and sample annotation table, especially for QC, batch inspection, or sample similarity assessment. Trigger keywords: hierarchical clustering, dendrogram, sample QC, batch inspection, sample similarity. NOT for: differential expression testing, gene clustering heatmaps, single-cell clustering workflows.
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Turns your protocol and analysis workflow into publication-ready Methods text. Use when writing or revising the Methods section of a biomedical manuscript, ensuring it complies with reporting guidelines (CONSORT, STROBE, PRISMA, TRIPOD), matches what is in the Results section, and satisfies journal-specific word limits and declarations. Also triggers on "write my methods", "revise my methods section", "how to report my statistics", "what do I need to include in methods for [study type]", or "make my methods CONSORT-compliant".
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Land a change everywhere the same fact is stated — enumerating the full surface inventory (landing copy, docs, machine-readable summaries, changelog badges repeated across every page, sitemap, README, descriptions embedded in code, and untyped frontend consumers of typed responses), generating a surface instead of restating it, drift tests where you cannot generate, never hand-maintaining a copy of a surface another codebase owns, shipping a paired PR when you change a format a different codebase decodes, and keeping overloaded product words apart. Use when adding or renaming a user-facing feature, editing product/marketing copy or docs, renaming a serialized response field, changing a serialization or share-link format, wiring one repo's output into another's checks, or reviewing a PR that touched only one place a fact appears.
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Use when the user is designing, prototyping, or rewriting a desktop app that must run on multiple OSes (macOS + Windows, optionally Linux) AND feel indistinguishable from a native app to its users — fast launch, native windowing, native input handling, native materials. Trigger words include "cross-platform desktop", "Electron alternative", "Tauri vs native", "WebView wrapper", "near-native performance", "Raycast architecture", "WebKit/WebView2 quirks", "WKWebView", "system tray app", "global hotkey app", "launcher app". Do NOT trigger this skill for pure web apps, pure mobile apps, or for greenfield projects that have no native-feel requirement.
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When the user wants to audit, review, or diagnose SEO issues on their site. Also use when the user mentions "SEO audit," "technical SEO," "why am I not ranking," "SEO issues," "on-page SEO," "meta tags review," or "SEO health check." For building pages at scale to target keywords, see programmatic-seo. For adding structured data, see schema-markup.
日本語の概要は準備中です。原文の説明を表示しています。
根据题目、建模分析和真实代码结果生成完整 Word 数学建模论文,用户显式要求时同时生成 LaTeX 论文。
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从官方或内置模板创建、编译和校验数学建模 LaTeX 论文项目,并可配合 DOCX 工具把完整 LaTeX 论文转换为 Word。
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创建、编辑、校验和转换 Word DOCX,支持把完整 LaTeX 论文转换为 DOCX,以及数学建模论文模板、原生公式、三线表、修订和批注。
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Use this skill when writing analytical SQL over time-series data with the TimescaleDB Toolkit (timescaledb_toolkit extension) hyperfunctions: approximate percentiles, statistical summaries, time-weighted averages, counter/gauge rates, uptime/heartbeat tracking, state durations, OHLC candlesticks, approximate distinct counts, top-N, and downsampling. **Trigger when user asks to:** - Compute percentiles/medians/p95/p99 over large or rolled-up time-series data - Compute rates or deltas from monotonic counters (Prometheus-style) or gauges - Compute time-weighted averages or integrals over irregularly sampled data - Track uptime/downtime from heartbeats, or time spent in each state - Build OHLC/candlestick or VWAP data for financial ticks - Store re-aggregatable summaries in continuous aggregates (two-step aggregation, rollup) - Approximate COUNT DISTINCT, find top-N / most frequent values, or downsample for charts **Keywords:** timescaledb_toolkit, hyperfunctions, percentile_agg, uddsketch, tdigest, approx_percentile, stats_agg, time_weight, counter_agg, gauge_agg, heartbeat_agg, state_agg, candlestick_agg, hyperloglog, approx_count_distinct, min_n, max_n, mcv_agg, lttb, asap_smooth, rollup, two-step aggregation
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Use this skill for planning, testing, and safely executing PostgreSQL schema migrations — especially when working with production data or shared databases. **Trigger when user asks to:** - Test a schema migration before applying it to production - Add, remove, or rename columns safely on a live table - Change a column's data type without downtime - Add or drop indexes, constraints, or foreign keys on large tables - Understand which ALTER TABLE operations lock the table - Roll back a failed migration - Plan a zero-downtime migration strategy - Fork a database to test a migration safely **Keywords:** migration, schema change, ALTER TABLE, add column, drop column, rename column, change type, zero downtime, lock, AccessExclusiveLock, concurrent index, forking, rollback, backfill, deploy Covers: lock-level reference for every common DDL operation, safe migration patterns, fork-based testing, zero-downtime column changes, index creation, constraint addition, backfill strategies, pre/post-migration validation, and rollback planning.
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Use this skill when creating database schemas or tables for Timescale, TimescaleDB, TigerData, or Tiger Cloud, especially for time-series, IoT, metrics, events, or log data. Use this to improve the performance of any insert-heavy table. **Trigger when user asks to:** - Create or design SQL schemas/tables AND Timescale/TimescaleDB/TigerData/Tiger Cloud is available - Set up hypertables, compression, retention policies, or continuous aggregates - Configure partition columns, segment_by, order_by, or chunk intervals - Optimize time-series database performance or storage - Create tables for sensors, metrics, telemetry, events, or transaction logs **Keywords:** CREATE TABLE, hypertable, Timescale, TimescaleDB, time-series, IoT, metrics, sensor data, compression policy, continuous aggregates, columnstore, retention policy, chunk interval, segment_by, order_by Step-by-step instructions for hypertable creation, column selection, compression policies, retention, continuous aggregates, and indexes.
日本語の概要は準備中です。原文の説明を表示しています。