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Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

日本語の概要は準備中です。原文の説明を表示しています。

Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.

日本語の概要は準備中です。原文の説明を表示しています。

Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.

日本語の概要は準備中です。原文の説明を表示しています。

Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.

日本語の概要は準備中です。原文の説明を表示しています。

Build UpSet plots to visualize set intersections beyond 4 sets (where Venn fails) using ComplexUpset (modern, ggplot2-grammar) or the unmaintained UpSetR, with explicit cardinality vs degree sorting, attribute panels, and query highlighting. Use when comparing overlap across many gene sets, peak sets, variant lists, or any set membership matrix where Venn diagrams become illegible.

日本語の概要は準備中です。原文の説明を表示しています。

Detects aberrant splicing in single rare-disease patients vs a control panel using FRASER 2.0 (Bioconductor; Beta-binomial autoencoder on Intron Jaccard Index, default delta cutoff 0.1, q hyperparameter), OUTRIDER (gene-level outlier expression via autoencoder denoising), LeafcutterMD (Dirichlet-multinomial outlier mode of LeafCutter for annotation-free junctions), and DROP (Snakemake pipeline integrating FRASER2 + OUTRIDER + monoallelic expression for clinical diagnostics). The statistical model is fundamentally different from differential splicing — single-sample-vs-cohort outlier detection rather than two-group comparison. Standard tool in EU rare-disease (Solve-RD) and NIH UDN programs. Use when applying RNA-seq to undiagnosed Mendelian disease, validating predicted splice variants in clinical samples, or detecting cryptic splicing in disease tissue.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about hazardous materials (hazmat) transportation under 49 CFR 171-180 — placarding requirements, segregation tables, hazmat employee training (49 CFR 172 Subpart H), Hazmat Safety Permit (HMSP), shipping papers, packaging groups, emergency response phone, security plans, hazmat endorsement on CDL, and bulk vs non-bulk distinctions. Cite specific 49 CFR section.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to understand the requirement that drivers must self-certify their non-excepted/excepted status with their state driver licensing agency. Covers § 383.71, the four self-cert options, and the state-to-CDL link.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about US-Canada cross-border CMV operations — CVOR (Commercial Vehicle Operator's Registration), NSC (National Safety Code), Ontario / Quebec / BC specific rules, US carrier obtaining Canadian operating authority, FAST card for drivers, customs (CBSA), Health Canada hazmat, and how Transport Canada equivalents differ from US FMCSA. Reference USMCA + Transport Canada NSC 14.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze a Coval adversarial / red-team testing report and turn it into an agent-hardening plan. Use when a user provides a Coval report URL, report export, run IDs, screenshots, or a per-scenario scorecard from an adversarial sweep and wants evidence-backed next steps such as prompt/guardrail changes, refusal hardening, verification fixes, escalation routing, or expanded attack coverage.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end Coval adversarial / red-team testing workflow. Builds one adversarial test set (12 core attack vectors plus legitimate controls, each with an expected-behavior checklist), creates a persistent "Adversarial User" persona and a Composite Evaluation metric that scores each scenario against its own expected behaviors, launches a multi-iteration run against the agent (voice or chat), polls for completion, builds a per-scenario pass/fail scorecard, and creates a saved report grouped by Test Case. Use when a user wants to follow the Adversarial & Red-Team Testing cookbook (https://docs.coval.dev/guides/adversarial-red-team-testing) without doing each step by hand. Triggers: "adversarial test set", "red team my agent", "jailbreak / prompt-injection testing", "test my agent against bad actors".

日本語の概要は準備中です。原文の説明を表示しています。

Next.js route metadata, per-route favicons, OpenGraph, and Twitter cards. Use when adding a route or layout, adding a favicon or social share image, auditing missing metadata, naming tab titles, or touching createRouteMetadata, createDynamicRouteMetadata, generateFaviconMetadata, or titlePrefix.

日本語の概要は準備中です。原文の説明を表示しています。

Compact two-icon Copy / Copy-for-AI controls (components/agent-copy). Use when adding copy buttons to a row, card, list, or record; merging duplicate Copy/JSON/AI controls; continuing the copy rollout; or writing a Copy-for-AI payload. NOT for markdown content actions (use rich-document-actions).

日本語の概要は準備中です。原文の説明を表示しています。

Adding a file type or upgrading any of its capability slots in the files feature (preview, edit, thumbnail, grid card, info, share, versions, conversion, diff, rail panel). Use when supporting a new extension or MIME type, building a previewer, touching FILE_TYPES, PreviewKind, FilePreview.tsx, EDITABLE_KINDS, or surfaces/single-file/, or working the FILE_SURFACES.md wishlist.

日本語の概要は準備中です。原文の説明を表示しています。

Platform agent skill and content blocks that teach agents a render block, building the block first if new. Use when asked to create the skill for a render block, skill-ify flashcards or quiz, add content blocks for a block, or add a new render block type. NOT for tool result displays (use create-tool-renderer).

日本語の概要は準備中です。原文の説明を表示しています。

The one association system (platform.associations) and schema-qualified table refs. Use when touching an M2M junction table, an associate_*/attach_*/tag_* RPC, FK columns used as tags, a 'things attached to X' list or card, or a PGRST205 / 42703 table-not-found on a bare .from().

日本語の概要は準備中です。原文の説明を表示しています。

AssociationEntitySelect, the name dropdown for the note, session, chat, or document a panel is bound to. Use when a surface must show that name and let the user rename, switch, unlink, or add new ('add a note switcher', 'show the session name'). NOT for count cards or row lists (use canonical-associations).

日本語の概要は準備中です。原文の説明を表示しています。

One-click contribution flow for Open Design (nexu-io/open-design) — even for non-coders. Pick one of four cards (ship a Skill or Design System you made with OD; translate docs; fix a typo / write a blog; report a bug), the agent validates and opens a PR (or issue) for you. Trigger words contribute to open design, ship my OD skill, ship my OD design system, translate OD docs, report an OD bug, od-contribute.

日本語の概要は準備中です。原文の説明を表示しています。

Teaches the AI to design like a high-end agency. Defines the exact fonts, spacing, shadows, card structures, and animations that make a website feel expensive. Blocks all the common defaults that make AI designs look cheap or generic.

日本語の概要は準備中です。原文の説明を表示しています。

Agent-to-Agent (A2A) protocol implementation patterns for Google ADK - exposing agents via A2A, consuming external agents, multi-agent communication, and protocol configuration. Use when building multi-agent systems, implementing A2A protocol, exposing agents as services, consuming remote agents, configuring agent cards, or when user mentions A2A, agent-to-agent, multi-agent collaboration, remote agents, or agent orchestration.

日本語の概要は準備中です。原文の説明を表示しています。

Generate A2UI 0.8 protocol compliant UI code. Use when building agent-driven interfaces, generating JSONL messages for surfaceUpdate/dataModelUpdate/beginRendering, creating forms, lists, cards, or any UI components that render across web/mobile/desktop platforms.

日本語の概要は準備中です。原文の説明を表示しています。

Use when you need to review, improve, or refactor Java code for generics quality — including avoiding raw types, applying the PECS (Producer Extends Consumer Super) principle for wildcards, using bounded type parameters, designing effective generic methods, leveraging the diamond operator, understanding type erasure implications, handling generic inheritance correctly, preventing heap pollution with @SafeVarargs, and integrating generics with modern Java features like Records, sealed types, and pattern matching. Part of the skills-for-java project

日本語の概要は準備中です。原文の説明を表示しています。

Codified expertise for managing carrier portfolios, negotiating freight rates, tracking carrier performance, allocating freight, and maintaining strategic carrier relationships. Informed by transportation managers with 15+ years experience. Includes scorecarding frameworks, RFP processes, market intelligence, and compliance vetting. Use when managing carriers, negotiating rates, evaluating carrier performance, or building freight strategies.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when working with the nuxt-ui-tools form runtime as a package consumer. It covers schema-driven forms, the provider-backed form API, inline rendering, overlay rendering, form pages with a section navigation, choice cards, and typed submit results.

日本語の概要は準備中です。原文の説明を表示しています。