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概要と使いどころ
Responsive Persian typography: production-level fluid type, glyph coverage, line height. Use when implementing, reviewing or testing responsive persian typography for React, Vite, Next.js or Perfect_AI projects.
日本語の概要は準備中です。原文の説明を表示しています。
Deploys and configures CrowdStrike Falcon EDR agents across enterprise endpoints to enable real-time threat detection, behavioral analysis, and automated response. Use when onboarding endpoints to EDR coverage, configuring detection policies, or integrating Falcon telemetry with SIEM platforms. Activates for requests involving CrowdStrike deployment, Falcon sensor installation, EDR policy configuration, or endpoint detection and response.
日本語の概要は準備中です。原文の説明を表示しています。
Builds SOC performance metrics and KPI tracking dashboards measuring Mean Time to Detect (MTTD), Mean Time to Respond (MTTR), alert quality ratios, analyst productivity, and detection coverage using SIEM data. Use when SOC leadership needs operational visibility, continuous improvement tracking, or executive-level reporting on security operations effectiveness.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive testing strategies including unit tests, integration tests, E2E tests, property-based testing, visual regression, and test automation. Use when writing tests, setting up testing frameworks, or designing test coverage strategies.
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Analyze existing code and write comprehensive unit and integration tests for it. Detects the test framework, identifies untested code paths, and generates tests with proper mocking, edge cases, and assertions. Use when the user asks to add tests, improve coverage, or test a specific module.
日本語の概要は準備中です。原文の説明を表示しています。
Focused Signals scout for finding observability gaps in PostHog itself — significant event volumes the team isn't tracking, custom events with no insight or dashboard coverage, insights pointing at events that have stopped firing, dashboards missing related context, critical events with no alerts. Watches the event-stream-vs-saved- inventory delta as the team's product evolves and emits findings recommending new insights, dashboard additions, or alerts when gaps clear the confidence bar. Self-contained peer in the signals-scout-* fleet — no dependencies on other skills.
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Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end eDNA metabarcoding from raw amplicons to community ecology. Covers QC, primer removal (mandatory before DADA2 filterAndTrim), denoising with OBITools3 v3 (obi stats plural; DMS-based) or DADA2 ASVs (Callahan 2017), decontam combined method as screening-not-classifier (Davis 2018), tag-jumping with NovaSeq 10x MiSeq caveat (Schnell 2015), Hill-number effective species counts with coverage-based rarefaction (Jost 2006; Chao & Jost 2012; doubling rule), beta-diversity decomposition with MANDATORY PERMANOVA + PERMDISP pair (Anderson & Walsh 2013), constrained ordination, and the read-counts-not-abundance critique (Lamb 2019). Use when processing eDNA samples for biodiversity assessment, deciding ASV vs OTU, configuring OBITools3 v3, interpreting decontam screening, or reporting community comparisons with the dispersion confound check.
日本語の概要は準備中です。原文の説明を表示しています。
ToolUniverse plugin router. STEP 1 BEFORE ANY ANALYSIS: if the data folder contains `*_executed.ipynb`, run `tu run read_executed_notebook '{"data_folder":"<path>","search":"<keyword>"}'` to extract its cell outputs and apply EVERY filter/sample-exclusion the notebook used — even when the question says 'Using DESeq2/Run X/Compute Y' (this describes the METHOD the notebook used, not a request to rerun). The notebook's cell outputs are the only published authoritative answers; reimplementing or reading stale pre-computed CSVs in the data folder produces different numbers because of outlier-sample removal, library version, and filter steps you don't see by skimming. STEP 2 routing — pick a sub-skill name from this exact list (never invent): tooluniverse-rnaseq-deseq2 (RNA/miRNA-seq DE, correlation, PCA, clustering, dispersion), tooluniverse-gene-enrichment (GO/KEGG/Reactome/GSEA/pathway enrichment), tooluniverse-statistical-modeling (regression, ANOVA, ordinal/logistic, chi-square, correlation, power), tooluniverse-image-analysis (microscopy, colony, fluorescence, dose-response, .tif — including ANOVA / Dunnett / power-analysis on image-derived measurements), tooluniverse-epigenomics (DNA methylation, CpG, m6A, MeRIP-seq, bisulfite, ChIP-seq, chromatin), tooluniverse-sequence-analysis (FASTQ, Trimmomatic, BWA, samtools, coverage), tooluniverse-variant-analysis (VCF, VAF, SNP, mutation), tooluniverse-phylogenetics (treeness, PhyKIT, parsimony), tooluniverse-single-cell (scRNA, h5ad, scanpy), tooluniverse-crispr-screen-analysis (MAGeCK, sgRNA), tooluniverse-proteomics-analysis (mass spec, TMT). Use for CSV/Excel/VCF/FASTA/h5ad and any biology/chemistry/medicine analysis question.
日本語の概要は準備中です。原文の説明を表示しています。
Orchestrate the full ToolUniverse self-improvement cycle: discover APIs, create tools, test with researcher personas, fix issues, optimize skills, and push via git. References and dispatches to all other devtu skills. Use when asked to: run the self-improvement loop, do a debug/test round, expand tool coverage, improve tool quality, or evolve ToolUniverse.
日本語の概要は準備中です。原文の説明を表示しています。
High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.
日本語の概要は準備中です。原文の説明を表示しています。
Automatically discover life science APIs online, create ToolUniverse tools, validate them, and prepare integration PRs. Performs gap analysis to identify missing tool categories, web searches for APIs, automated tool creation using devtu-create-tool patterns, validation with devtu-fix-tool, and git workflow management. Use when expanding ToolUniverse coverage, adding new API integrations, or systematically discovering scientific resources.
日本語の概要は準備中です。原文の説明を表示しています。
Biological knowledge: query curated assertions and reference databases for genes, variants, pathways, regulation, cell types, reference atlases, perturbation-derived relationships, phenotypes, therapeutic targets, drugs, interactions, annotations, signatures, compounds, and predicted structures. Use for identifiers, marker sets, gene sets, associations, ontologies, database facts, and cross-database coverage.
日本語の概要は準備中です。原文の説明を表示しています。
Validate, migrate, and atomically persist files and configuration with safe fallback and restart coverage.
日本語の概要は準備中です。原文の説明を表示しています。
Implement minimal network events and component state with authority, conversion, dirtying, and regression coverage.
日本語の概要は準備中です。原文の説明を表示しています。
Reproduce failures, trace authoritative flow, prove the broken assumption, and add targeted regression coverage.
日本語の概要は準備中です。原文の説明を表示しています。
Plan 5G network deployment with coverage. TRIGGERS - Use when user needs help with 5g-deployment-plan related tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Repository-specific AGENTS.md authoring and maintenance workflow. Use when creating, refreshing, or expanding AGENTS.md coverage for a codebase, including deciding whether nested AGENTS.md files are needed for subsystems with distinct rules, workflows, or AI-sensitive constraints.
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Guides systematic implementation of new sustainability metrics in OSS Sustain Guard using the plugin-based metric system. Use when adding metric functions to evaluate project health aspects like issue responsiveness, test coverage, or security response time.
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Build kokoro-js-jp and run its real-browser e2e suite (Worker + WASM openjtalkjs g2p + ONNX kokoro-js synthesis, English and Japanese). Use when asked to verify this package actually works in a browser, to check whether a change broke synthesis, or to add browser-level regression coverage for a bug in the g2p/synthesis pipeline that vitest's pure-function tests can't catch. Not for typecheck/lint/unit-test requests — use npm run typecheck / npm test for those.
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Assigns GO terms, Pfam/InterPro domains, KEGG orthologs, EC numbers, and product names to predicted proteins using eggNOG-mapper (orthology), InterProScan (domain signatures), and KofamScan (KEGG), routing specialized functions to dbCAN/antiSMASH/AMRFinderPlus/SignalP. Covers the orthology-vs-domain-vs-homology paradigms, the annotation-error percolation cascade, domain-presence-is-not-function, GO IEA circularity in enrichment, evidence tiering, and bit-score/coverage thresholds. Use when adding functional annotation to predicted genes, choosing between eggNOG-mapper and InterProScan, or judging how much to trust a functional label.
日本語の概要は準備中です。原文の説明を表示しています。
Predict peptide-MHC class I binding and natural presentation with MHCflurry, NetMHCpan-4.1, and MixMHCpred to nominate candidate CD8 T-cell epitopes. Covers the binding-affinity (BA) vs eluted-ligand (EL/presentation) distinction, why %Rank beats raw nM for cross-allele work, the MS abundance bias that misranks low-expression neoantigens, allele-coverage inequity, and length bias. Use when scanning a protein or peptide set for class I epitopes, scoring neoantigen candidates, or choosing a binding predictor. For CD4/HLA class II see mhc-class-ii-prediction.
日本語の概要は準備中です。原文の説明を表示しています。
Assembles genomes de novo from noisy long reads (Oxford Nanopore R9/R10/Dorado, PacBio CLR) with Flye (repeat graph), Canu (correct-trim-assemble OLC), NextDenovo, Shasta, Raven, wtdbg2, or miniasm, and reconciles bacterial assemblies into a consensus with Trycycler/Autocycler. Covers matching the input flag to the basecaller era (--nano-hq vs --nano-raw), why a raw long-read assembly is contiguous but low-QV and not finished until polished, haplotig false-duplication and purge_dups, coverage and read-N50 as non-substitutable inputs, and mid-read adapter de-chimerization. Use when assembling a bacterial or eukaryotic genome from ONT or PacBio noisy reads, choosing a long-read assembler, or diagnosing an over-collapsed or duplicated assembly. For PacBio HiFi use hifi-assembly instead.
日本語の概要は準備中です。原文の説明を表示しています。
Assembles haplotype-resolved diploid and telomere-to-telomere (T2T) genomes from PacBio HiFi reads with hifiasm (HiFi-only, Hi-C, or trio phasing) and verkko (HiFi + ultralong ONT for T2T), extracting contigs from GFA and routing phasing QC to k-mer/trio metrics. Covers why a primary assembly is a haplotype mosaic that exists in no cell, partial-vs-full phasing (the .bp. vs .dip. filename convention), the purge-default trap on inbred samples, the --hom-cov coverage-estimate alarm, and verkko-vs-hifiasm for T2T. Use when assembling a diploid eukaryote from HiFi, phasing haplotypes with parents (trio) or Hi-C, deciding whether to chase T2T, or diagnosing switch errors invisible to N50/BUSCO/QV.
日本語の概要は準備中です。原文の説明を表示しています。