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Build accessible web applications following WCAG 2.1/2.2 guidelines with proper semantic HTML, ARIA attributes, keyboard navigation, screen reader support, and inclusive design. Use when implementing ARIA labels and roles, ensuring keyboard navigation, supporting screen readers, providing text alternatives for images, managing focus, creating accessible forms, building inclusive UI components, testing with accessibility tools, meeting WCAG compliance levels, or designing for users with disabilities.

日本語の概要は準備中です。原文の説明を表示しています。

YC Office Hours — two modes. Startup mode: six forcing questions that expose demand reality, status quo, desperate specificity, narrowest wedge, observation, and future-fit. Builder mode: design thinking brainstorming for side projects, hackathons, learning, and open source. Saves a design doc. Use when asked to "brainstorm this", "I have an idea", "help me think through this", "office hours", or "is this worth building". Proactively invoke this skill (do NOT answer directly) when the user describes a new product idea, asks whether something is worth building, wants to think through design decisions for something that doesn't exist yet, or is exploring a concept before any code is written. Use before /plan-ceo-review or /plan-eng-review. (gstack)

日本語の概要は準備中です。原文の説明を表示しています。

One-shot brand-faithful presales redesign of a website page. The user provides only the URL; everything else — extraction, tension identification, three differentiated variants (one fully cinematic), validation — is derived from the captured brand surface. Use when the user asks to "uplift", "refresh", or "redesign a site for presales" without wanting to coordinate the extract / direct / prototype chain themselves.

日本語の概要は準備中です。原文の説明を表示しています。

Bulk-retouch a folder of portrait photos using Adobe tools — designed for wedding photographers and event photographers who need fast, walk-away batch processing. Use this skill when the user says "retouch my photos", "batch process these portraits", "process my wedding photos", "clean up this folder of images", "run my headshots through Adobe", or uploads/selects a folder of photos and wants them polished and ready to review. Automatically applies auto-straighten, auto-tone, and auto-light to every image. Outputs a preview grid and download folder. Access: 🔐 Signed-In required | Gen AI: ❌

日本語の概要は準備中です。原文の説明を表示しています。

Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

日本語の概要は準備中です。原文の説明を表示しています。

Build a throwaway prototype to flesh out a design before committing to it. Routes between two branches — a runnable terminal app for state/business-logic questions, or several radically different UI variations toggleable from one route. Use when the user wants to prototype, sanity-check a data model or state machine, mock up a UI, explore design options, or says "prototype this", "let me play with it", "try a few designs".

日本語の概要は準備中です。原文の説明を表示しています。

Upgrades existing websites and apps to premium quality. Audits current design, identifies generic AI patterns, and applies high-end design standards without breaking functionality. Works with any CSS framework or vanilla CSS.

日本語の概要は準備中です。原文の説明を表示しています。

Derive and implement first-principles audio-coupled haptic and kinetic UI feedback. Use when designing, reviewing, or coding haptics/audio for mobile apps, native iOS/Android, React Native/Expo, SwiftUI, games, detent pickers, toggles, sliders, page curls, scroll gestures, wallet/signature flows, Solana transactions, backend/realtime state changes, confirmations, settlements, and semantic UI events where feedback should follow signal math instead of ad hoc vibration calls.

日本語の概要は準備中です。原文の説明を表示しています。

Generate 5–10 business idea candidates from a blank page or a founder's domain context — using pain mining, jobs-to-be-done, trend × capability mapping, constraint relaxation, adjacency search, and founder-market-fit prompts. Each candidate is a structured idea card (segment, JTBD, current alternative, why-now, distribution wedge, monetisation, "feels like"). Load when the user asks to generate business ideas, brainstorm startup ideas, find ideas to work on, says "what business should I start", "give me startup ideas", "I don't know what to build", "ideate ventures", "blank-page idea generation", "find me a startup idea", "explore business opportunities". Sub-skill of `venture-exploration`. Hard-bans "Uber for X" / "AI for X" with no specific JTBD, "everyone" segments, and idea cards missing any of the 7 required fields. Does NOT design or evaluate ideas generated — for that use `idea-evaluation`.

日本語の概要は準備中です。原文の説明を表示しています。

Design automated evaluation pipelines for LLM and agent systems — combining deterministic checks, statistical metrics, and LLM-as-judge scoring into repeatable, CI-integrated eval suites. Load when the user asks to set up automated evals, design an eval pipeline, integrate evals into CI/CD, create an eval suite, do eval-driven development, or says "automate my evals", "CI eval integration", "evaluation pipeline", "continuous evaluation", "monitoring eval quality", "set up regression testing for my agent". Sub-skill of eval-output orchestrator.

日本語の概要は準備中です。原文の説明を表示しています。

Translate an approved experiment spec into a launch runbook — platform binding (PostHog primary), feature flag setup, assignment unit, exposure event definition, instrumentation QA, dashboard wiring, ramp plan, monitoring, and rollback procedure. Platform-agnostic core with one strong PostHog adapter shipped; GrowthBook, Statsig, LaunchDarkly, Optimizely, and Eppo documented as a single mapping table the user adapts. Load when a spec is approved and ready to launch, or when the user says "set up the experiment", "wire this up in PostHog", "implement the test", "create the runbook", "launch checklist for this test", or when the experimentation orchestrator routes here.

日本語の概要は準備中です。原文の説明を表示しています。

Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.

日本語の概要は準備中です。原文の説明を表示しています。

Implement several variations of a design directly inside the running app, on the real page/route, with a live switcher to toggle between them in the browser, then recommend one and fold the winner into the real code. Variants are real implementations judged against real data, layout, and density (not an isolated mockup). Use this skill whenever the user wants to try design options live in the app, prototype changes directly on a real page, add a variant switcher, compare layouts in-context, asks to "build a few versions of this page", "try variants on the real screen", "switch between designs in the app", "implement this with a toggle", or says "real-prototype this". For a safe standalone .html copy that never touches the app, use the prototype skill instead.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "create AGENTS.md", "update AGENTS.md", "maintain agent docs", "set up CLAUDE.md", or needs to keep agent instructions concise. Enforces research-backed best practices for minimal, high-signal agent documentation.

日本語の概要は準備中です。原文の説明を表示しています。

Designs pegRNAs and nicking guides for prime editing (PE) -- choosing the nick/strand, tuning the primer-binding site (PBS) and reverse-transcription template (RTT) as a per-locus panel, selecting the PE system (PE2/PE3/PE3b/PE4/PE5/PEmax/PE7), adding MMR-evading and PAM-disrupting silent edits, appending epegRNA 3' motifs (tevopreQ1/mpknot), and ranking with PRIDICT/DeepPrime. Covers twinPE/PASTE for large insertions and the prime-vs-base-editing decision. Use when designing a scarless point mutation, small insertion/deletion, or any of the 12 base conversions without a double-strand break, when efficiency is low and MMR inhibition or pegRNA stabilization is needed, or when routing a large insertion to an integrase method. Generic guide scoring and base editing are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal peptide changes, IDR alterations, coding-potential shifts). Tools include IsoformSwitchAnalyzeR v2 (auto-selects satuRn for >5 reps else DEXSeq), the manual DRIMSeq -> DEXSeq/satuRn -> stageR DTU pipeline, and fishpond/swish for inferential-uncertainty-aware DTE. Distinguishes DTU from DGE and DTE; integrates external annotators (CPC2, Pfam, SignalP, IUPred2A or DeepTMHMM). Use when investigating how splicing differences alter protein function or trigger NMD-mediated degradation.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when a carrier's CSA peer group changes. Covers what triggers reassignment, how percentile changes affect alert status, and how to interpret the shift.

日本語の概要は準備中です。原文の説明を表示しています。

Architect data fetching with TanStack Query v5, SWR, optimistic updates, prefetching, and cache invalidation strategies. Activate on: React Query, SWR, optimistic updates, cache invalidation, prefetching, stale-while-revalidate, infinite queries. NOT for: REST API design (use api-architect), database queries (use database skills), GraphQL schema (use graphql-expert).

日本語の概要は準備中です。原文の説明を表示しています。

Architecture-level decisions for putting a CDN in front of a web app's static assets, API responses, and file/media delivery: provider selection (hyperscaler vs. specialist $/GB), signed-URL / tokenized access for gating private content at the edge, cache invalidation strategy (versioned URLs vs. purge APIs), origin shield / tiered caching for high-miss-rate content, and CDN-layer geo-restriction. Use when deciding which CDN to put in front of a new or growing service, when private/paywalled files need edge delivery without an origin round-trip per request, or when purge/invalidation behavior is being designed rather than debugged. NOT for HTTP cache-control header syntax, Vary, stale-while-revalidate, or surrogate-key purge mechanics (see `cdn-cache-control-headers`); NOT for Cloudflare-specific product configuration once Cloudflare is already chosen (see `cloudflare`); NOT for video-specific transcoding, adaptive bitrate ladders, or streaming-protocol packaging (see `managed-video-streaming-pipeline`).

日本語の概要は準備中です。原文の説明を表示しています。

Use when wrangler deploys silently fail or produce wrong artifacts, secrets upload as empty strings, custom domain DNS is not resolving, route assignment broke after rename, observability/tail logs are needed, D1/KV/R2 bindings are missing, OAuth scope errors block a command, cookies on a redirect are not attaching, or the worker exceeds CPU time. Triggers: "Tenant or user not found", "Authentication error" on wrangler d1 push, secret length is 0 after upload, route returns origin not worker, "compatibility_date too old", 1101 errors, custom_domain assignment lost on script rename. NOT for AWS Lambda / Vercel Edge / Deno Deploy (different runtimes), Cloudflare Zero Trust, or R2-specific tuning.

日本語の概要は準備中です。原文の説明を表示しています。

Design polished terminal UX for CLIs and TUIs. Use for setup flows, dashboards, tables, and actionable errors. NOT for web UIs, desktop windows, API schemas, or shell automation.

日本語の概要は準備中です。原文の説明を表示しています。

Cryptographic security for agentic systems — zero-trust agent networking, signed message envelopes (JWS/JWE), capability-based security (ocaps), Merkle tree audit trails, WASM sandboxing, and formal verification. Covers CLI dev tool security, mTLS between agents, permission boundaries (least privilege for AI agents), and supply chain security for skills/plugins. Activate on: "agent security", "zero trust agents", "secure agent communication", "capability-based security", "ocap", "signed messages between agents", "agent audit trail", "sandbox agent execution", "agent permissions", "mTLS agents", "cryptographic verification", "agent supply chain", "OWASP agentic", "prove agent did X", "tamper-proof agent logs". NOT for: application-level SAST scanning (use security-auditor), network firewall rules (use infrastructure), SOC2/HIPAA compliance (organizational), or prompt injection defense (use prompt-engineer).

日本語の概要は準備中です。原文の説明を表示しています。

Turn a large dataset (an existing oversized Coval test set, an export of past conversations, or a CSV/JSON of cases) into a small, high-signal Coval test set by removing duplicates, identifying unique scenarios, and selecting a representative, failure-weighted subset — then bulk-loading it with no row cap. Use when the user says "I have thousands of cases", "dedupe my test set", "my test set is too big", "turn this dataset into a test set", "pick representative scenarios", or "my CSV import only kept 10 / uploaded everything".

日本語の概要は準備中です。原文の説明を表示しています。