「persona」の検索結果

Identify tumor neoantigens from somatic variants with pVACtools (pVACseq/pVACfuse/pVACbind/pVACvector/pVACview) for personalized cancer vaccines and checkpoint biomarkers. Encodes the field's hard truth that binding prediction is the easy, near-solved part and single-digit-percent PPV lives downstream — so it centers clonality/CCF, HLA LOH (the silent invalidator), expression, proximal-variant phasing, agretopicity/foreignness quality, and the predicted->presented->immunogenic validation tiers. Use when nominating vaccine targets, ranking neoantigens, or building a tumor-to-candidate pipeline. Binding details in mhc-binding-prediction; ranking in immunogenicity-scoring.

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Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.

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Amplify safe or boring designs to make them more visually interesting and stimulating. Increases impact while maintaining usability. Use when the user says the design looks bland, generic, too safe, lacks personality, or wants more visual impact and character.

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Evaluate design from a UX perspective, assessing visual hierarchy, information architecture, emotional resonance, cognitive load, and overall quality with quantitative scoring, persona-based testing, and actionable feedback. Use when the user asks to review, critique, evaluate, or give feedback on a design or component.

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Agente que simula Bill Gates — cofundador da Microsoft, arquiteto da industria de software comercial, estrategista tecnologico global, investidor sistemico e filantropo baseado em dados.

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Auri: assistente de voz inteligente (Alexa + Claude claude-opus-4-20250805). Visao do produto, persona Vitoria Neural, stack AWS, modelo Free/Pro/Business/Enterprise, roadmap 4 fases, GTM, north star WAC e analise competitiva.

日本語の概要は準備中です。原文の説明を表示しています。

Create custom AI subagents with proper plugin structure, persona generation, and companion routing skills.

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Urdu-first digital experiences with native RTL support, Nastaliq typography, and bilingual Urdu/Latin harmony. For editorial, personal, and publication layouts.

日本語の概要は準備中です。原文の説明を表示しています。

Vibrant, personality-driven design with bold colors, playful graphics, and dynamic layouts that balance creativity with structure.

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Use when the user wants to evolve the features of a PRD roadmap with user stories — 'refinar as histórias da feature', 'escrever histórias de usuário', 'critérios de aceite', 'regras de negócio da feature', 'deixar a feature pronta', 'user stories for FT01' — one feature at a time, interviewing the human until each story meets the Definition of Ready: persona, value, INVEST, CA (Gherkin, happy and error paths) and RN from the PRD. Do NOT use to create the roadmap (prd-roadmap) or to change requirements without stories (prd-refine).

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Use quando o usuário quiser criar um GitHub Project — 'criar um project no github', 'novo board', 'project a partir de template', 'copiar project modelo' — a partir de um preset (roadmap-produto, kanban, scrum) apresentado e personalizável antes de criar, ou copiando um Project-modelo. Não use para publicar um roadmap (github-publish) nem para mexer em issues (github-issues).

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Design precise, production-grade enterprise UI — dashboards, admin panels, SaaS interfaces, and data-heavy applications. Use this skill for professional software interfaces that need Jony Ive-level craft: clean, minimal, functional, with intentional personality. Do NOT use for creative landing pages, marketing sites, or experimental/artistic frontends.

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Define, documenta e aplica a voz da marca — formalidade, personalidade, vocabulário preferido, palavras proibidas e tratamento do leitor. Use quando o usuário disser "voz da marca", "tom de voz", "brand voice", "guia de estilo", "padronizar o tom", "não parece nossa marca", "manual de redação", ou quando precisar auditar se um texto está aderente. Extrai a voz de amostras reais em vez de inventar adjetivos, e grava o resultado na seção 5 de .claude/pwdev-copy-context.md para todas as demais skills consumirem.

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Write B2B cold emails and follow-up sequences that get replies. Use when the user wants to write cold outreach emails, prospecting emails, cold email campaigns, sales development emails, or SDR emails. Also use when the user mentions "cold outreach," "prospecting email," "outbound email," "email to leads," "reach out to prospects," "sales email," "follow-up email sequence," "nobody's replying to my emails," or "how do I write a cold email." Covers subject lines, opening lines, body copy, CTAs, personalization, and multi-touch follow-up sequences. For warm/lifecycle email sequences, see email-sequence. For sales collateral beyond emails, see sales-enablement.

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When the user wants to create sales collateral, pitch decks, one-pagers, objection handling docs, or demo scripts. Also use when the user mentions 'sales deck,' 'pitch deck,' 'one-pager,' 'leave-behind,' 'objection handling,' 'deal-specific ROI analysis,' 'demo script,' 'talk track,' 'sales playbook,' 'proposal template,' 'buyer persona card,' 'help my sales team,' 'sales materials,' or 'what should I give my sales reps.' Use this for any document or asset that helps a sales team close deals. For competitor comparison pages and battle cards, see competitor-alternatives. For marketing website copy, see copywriting. For cold outreach emails, see cold-email.

日本語の概要は準備中です。原文の説明を表示しています。

Interactive developer experience plan review. Explores developer personas, benchmarks against competitors, designs magical moments, and traces friction points before scoring. Three modes: DX EXPANSION (competitive advantage), DX POLISH (bulletproof every touchpoint), DX TRIAGE (critical gaps only). Use when asked to "DX review", "developer experience audit", "devex review", or "API design review". Proactively suggest when the user has a plan for developer-facing products (APIs, CLIs, SDKs, libraries, platforms, docs). (gstack) Voice triggers (speech-to-text aliases): "dx review", "developer experience review", "devex review", "devex audit", "API design review", "onboarding review".

日本語の概要は準備中です。原文の説明を表示しています。

Build a personalized learning roadmap with milestones and practice checkpoints

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Use when the user asks to switch AI role/mode/persona or uses role-trigger words such as Captain, Coordinator, 寫文章, 寫文章模式, 文章模式, 技術文章, 部落格, 出版, 預覽. Routes the request to Project Captain, Publishing Director, or Article Writing Mode, loads the matching keep memory when available, and applies the role's workflow without excessive roleplay.

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Orchestrate one or more thinking frameworks to work through any problem, decision, document, or idea rigorously. Diagnoses which frameworks fit — inversion, pre-mortem, assumption-mapping, socratic, adversarial-hat — then guides the user through them in the right sequence. Load when the user asks for deep thinking, says "help me think through this properly", "apply your best thinking frameworks", "I need to think carefully before deciding", or "what thinking tools should I use here". Also the entry point for any complex problem where the right framework is unclear. Covers product decisions, engineering tradeoffs, personal decisions, strategy, creative challenges — any domain.

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Create focused role prompts for agents in multi-agent topologies. Load when agent-builder needs role prompts for agents, or when a user asks to "create an agent prompt", "write a role prompt", "define agent identity", "write an agent role", "prompt for this agent", "write instructions for this agent", "agent persona". Scope: agent role prompts only (v1). System prompts, task prompts, and skill invocation prompts are future TODOs.

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Analyzes your recent Codex chat history to identify coding patterns, development gaps, and areas for improvement, curates relevant learning resources from HackerNews, and automatically sends a personalized growth report to your Slack DMs.

日本語の概要は準備中です。原文の説明を表示しています。

Expert C4 Context-level documentation specialist. Creates high-level system context diagrams, documents personas, user journeys, system features, and external dependencies.

日本語の概要は準備中です。原文の説明を表示しています。

Agente que simula Bill Gates — cofundador da Microsoft, arquiteto da industria de software comercial, estrategista tecnologico global, investidor sistemico e filantropo baseado em dados.

日本語の概要は準備中です。原文の説明を表示しています。

Auri: assistente de voz inteligente (Alexa + Claude claude-opus-4-20250805). Visao do produto, persona Vitoria Neural, stack AWS, modelo Free/Pro/Business/Enterprise, roadmap 4 fases, GTM, north star WAC e analise competitiva.

日本語の概要は準備中です。原文の説明を表示しています。