「red」の検索結果

Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.

日本語の概要は準備中です。原文の説明を表示しています。

Trains and applies base-resolution deep learning models on ChIP-seq / ChIP-nexus / CUT&RUN data. Uses BPNet (Avsec 2021 Nat Genet 53:354; soft motif syntax from ChIP-nexus), chromBPNet (Pampari A et al 2025 Nat Genet; bias-factorized base-resolution profiles), EnFormer (Avsec 2021 Nat Methods 18:1196; 196 kb input, ~100 kb effective receptive field), DeepSEA (Zhou 2015; multi-task CNN), and JASPAR 2026 deep-learning collection (1259 BPNet ChIP models). Performs in silico mutagenesis for variant-effect prediction, DeepLIFT/Grad attribution, and TF-MoDISco motif discovery from attribution scores. Use when predicting variant effects on TF binding, discovering soft motif syntax / cooperativity, integrating ChIP-seq with sequence-only predictions, or applying precomputed JASPAR Deep Learning models to new variants.

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Designs PROTACs, molecular glues, and bivalent degraders with explicit handling of E3 ligase choice (VHL, CRBN, IAP, MDM2, KEAP1), linker design (length, composition, rigidity), ternary complex prediction (PRosettaC, DeepTernary, AlphaFold3 with constraints), cooperativity (alpha), DC50 / Dmax characterization, hook effect, and prediction-experiment reconciliation. Use when designing targeted protein degraders, planning linker SAR, predicting ternary complex stability, or building generative degrader workflows.

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Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS. Use when narrowing a GWAS lead SNP to a 95 percent credible set, choosing between in-sample and reference LD, calibrating non-sparse loci with SuSiE-inf or FINEMAP-inf, integrating functional priors via PolyFun, fine-mapping across ancestries with SuSiEx, diagnosing LD mismatch via estimate_s_rss and kriging_rss, handling HLA or long-range LD, or feeding credible sets into coloc.susie for colocalization.

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Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

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Use this skill when the user asks about workers compensation for trucking — required by state law, classification of drivers, premium calculation (rate × experience modifier × payroll), Common Claim types in trucking, returning injured drivers to work, claims management, premium reduction strategies, and the difference between WC and Occupational Accident insurance for owner-operators. Reference state WC laws + IFTA / fleet insurance.

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Warehouse cost reduction, auto-scaling, query optimization, and lifecycle policies for data infrastructure. Activate on: data cost, warehouse credits, cost reduction, auto-scaling, lifecycle policy, cold storage, cost monitoring, resource optimization. NOT for: query performance tuning (use data-warehouse-optimizer), batch job optimization (use batch-processing-optimizer).

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Produces a narrow-interval quality signal for a WinDAGs skill that a third party can verify without inspecting model weights or method internals. The mechanism is attribution-kNN over a tamper-evident outcome log (task→skills→accept/reject store), combined with a conformal-prediction calibration certificate that provides a formal coverage guarantee. Thompson/Beta sampling is explicitly rejected as a category error: it produces a selection signal for stationary i.i.d. rewards, not an attestation signal for context-dependent LLM output quality. The resulting bundle — outcome-log Merkle root + conformal threshold + optional TEE guardrail signature — constitutes a "narrow-interval trust" credential: verifiable, bounded, and internals-opaque.

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Redis caching patterns, cache-aside, write-through, TTL strategies, and invalidation. Activate on: caching, Redis, cache invalidation, cache-aside, write-through, TTL, CDN cache, stale-while-revalidate. NOT for: CDN/reverse proxy setup (use api-gateway-reverse-proxy-expert), database query optimization (use data-warehouse-optimizer).

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Data structures and serialization formats for agent-to-agent communication. Covers message envelopes, structured output schemas, capability declarations, task handoff payloads, error/retry signaling, and context windows as data structures. Compares the version-pinned A2A, MCP, and JSON-RPC role boundaries covered by this bundle; OpenAI and LangChain-specific APIs require their own current sources. Teaches when to use rigid schemas versus free-form content with validation, typed versus untyped boundaries, and streaming versus batch. Activate on: "agent message format", "agent communication schema", "agent-to-agent protocol", "A2A protocol", "MCP message format", "structured output for agents", "agent interop", "interchange format", "agent serialization", "task handoff format", "capability declaration". NOT for: what agents say to each other (use agent-conversation-protocols), orchestration topology (use multi-agent-coordination), building agent infrastructure (use agentic-infrastructure-2026).

日本語の概要は準備中です。原文の説明を表示しています。

Design and audit a pricing function for variable-cost agent labor. Choose among per-seat, metered, credits, hybrid, and outcome pricing; name buyer value and cost metrics separately; calculate a reproducible cost floor; require pre-commitment guardrails; and stress-test declared personas. Use for offline pricing-design evidence, not billing implementation or runtime control. NOT for production billing, payment collection, or runtime spend enforcement.

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Author a pull request an AI coding agent can actually get merged: a scoped, coherent diff; a Summary and Test Plan backed by real evidence; correct triage of required-and-blocking CI gates versus external/advisory checks (e.g. a Cloudflare Pages preview build); draft-while-WIP discipline; named fixup commits for real review findings; and a clean landing through a merge queue without force-pushing or bypassing branch protection. Use when opening, updating, triaging red CI on, or landing an agent-authored GitHub PR. NOT for this repo's internal release ceremony, actor embodiments, or contributor mirror-sync mechanics (use port-daddy-internal-dev), tracking backlog/issue lifecycle across a board (use agent-issue-tracker-workflow), or deciding what to build next / sequencing a roadmap (use legible-roadmap-with-sidequests).

日本語の概要は準備中です。原文の説明を表示しています。

Detect, validate, and generate Schema.org structured data. JSON-LD format preferred. Use when user says "schema", "structured data", "rich results", "JSON-LD", or "markup".

日本語の概要は準備中です。原文の説明を表示しています。

The frontend Error Inspector capture system (captureError, lib/diagnostics/**). Use when wiring a new CapturedErrorSource or adapter, calling captureError from a new site, picking a red/orange/yellow tier or errorTierRules downgrade, or turning a console.error or swallowed catch into a captured error.

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Redux state for agent execution and firing agent shortcuts. Use when editing features/agents/redux/, building agent UI, creating a conversation, touching assembleRequest or NDJSON stream state, wiring agent-state selectors, adding a per-conversation capability, or triggering a shortcut from a button, menu, or code (useShortcutTrigger, launchAgentExecution).

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Create an Agent SKILL.md fallback for an existing find-XXXX finder that relies on a fragile discovery foundation — above all LLM_DECOMPILE (patterns C/D/E), which matches the decompiled shape of a predecessor function against a stored reference and breaks when a symbol is inlined or de-inlined in a way the reference does not cover. The generated fallback coexists with the preprocessor and runs only when it returns failure, recovering every target robustly by decompiling the predecessor and following the inline/de-inline boundary with semantic anchors. Use when a finder broke on a game update, or you want to durably backstop one before it does. The recipe generalizes to any finder foundation. Triggers: create agent skill fallback, add SKILL.md fallback, robust fallback for finder, backstop LLM_DECOMPILE finder, final guarantee skill

日本語の概要は準備中です。原文の説明を表示しています。

Azure Identity SDK for Rust authentication. Use for DeveloperToolsCredential, ManagedIdentityCredential, ClientSecretCredential, and token-based authentication.

日本語の概要は準備中です。原文の説明を表示しています。

Complete knowledge domain for Firecrawl v2 API - web scraping and crawling that converts websites into LLM-ready markdown or structured data. Use when: scraping websites, crawling entire sites, extracting web content, converting HTML to markdown, building web scrapers, handling dynamic JavaScript content, bypassing anti-bot protection, extracting structured data from web pages, or when encountering "content not loading", "JavaScript rendering issues", or "blocked by bot detection". Keywords: firecrawl, firecrawl api, web scraping, web crawler, scrape website, crawl website, extract content, html to markdown, site crawler, content extraction, web automation, firecrawl-py, firecrawl-js, llm ready data, structured data extraction, bot bypass, javascript rendering, scraping api, crawling api, map urls, batch scraping

日本語の概要は準備中です。原文の説明を表示しています。

Extract structured data from LLM responses with Pydantic validation, retry failed extractions automatically, parse complex JSON with type safety, and stream partial results with Instructor - battle-tested structured output library

日本語の概要は準備中です。原文の説明を表示しています。

Write comprehensive failing tests following TDD red phase principles.

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Master modern business analysis with AI-powered analytics, real-time dashboards, and data-driven insights. Build comprehensive KPI frameworks, predictive models, and strategic recommendations. Use PROACTIVELY for business intelligence or strategic analysis.

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Identifies and exploits insecure local data storage vulnerabilities in Android and iOS mobile applications including unencrypted databases, world-readable files, insecure SharedPreferences, plaintext credential storage, and improper keychain/keystore usage. Use when performing mobile penetration testing focused on OWASP M9 (Insecure Data Storage) or assessing compliance with MASVS-STORAGE requirements. Activates for requests involving mobile data storage security, local storage exploitation, SharedPreferences analysis, or mobile data leakage assessment.

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Red team engagement planning is the foundational phase that defines scope, objectives, rules of engagement (ROE), threat model selection, and operational timelines before any offensive testing begins.

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Exploit misconfigured Active Directory Certificate Services (AD CS) ESC1 vulnerability to request certificates as high-privileged users and escalate domain privileges during authorized red team assessments.

日本語の概要は準備中です。原文の説明を表示しています。