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Resolve conflicts and merges when several branches are open against one repo at the same time — the hotspot files every change must touch (registry manifests, a single version field, shared tool config, one aggregated test module, tracked build output), union-vs-recompute-vs-rebuild as three different correct resolutions, generated artifacts that must never be merged, non-deterministic serialization that makes every branch conflict, renumbered identifiers that git cannot show you, and why a clean auto-merge is not a passing test. Use when rebasing or merging a long-lived branch, resolving conflict markers, reviewing a merge commit, deciding what a repo should commit vs generate, or setting up a repo that will take parallel contributions.

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Land a change everywhere the same fact is stated — enumerating the full surface inventory (landing copy, docs, machine-readable summaries, changelog badges repeated across every page, sitemap, README, descriptions embedded in code, and untyped frontend consumers of typed responses), generating a surface instead of restating it, drift tests where you cannot generate, never hand-maintaining a copy of a surface another codebase owns, shipping a paired PR when you change a format a different codebase decodes, and keeping overloaded product words apart. Use when adding or renaming a user-facing feature, editing product/marketing copy or docs, renaming a serialized response field, changing a serialization or share-link format, wiring one repo's output into another's checks, or reviewing a PR that touched only one place a fact appears.

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Review a change to the ffmpeg-skill repository for the failures its own contract makes possible — a claim in a result document that is true at one layer and false at the layer a caller reads, a new flag that reaches the code but not the contract/docs/demo surfaces, a "bug" that docs/design-decisions.md already decided with a pinning test, a fix with no regression test, a new runtime dependency or a raw ffmpeg shell call that breaks the scope boundary, a SKILL.md line added without one trimmed, a review that re-derives findings from a summary instead of the tree at the reviewed commit. Use when asked to review a PR or diff in this repository, when authoring code here and needing a pre-commit check, or when triaging an external review or audit report about this codebase.

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Generates complete conventional oncology bulk-transcriptome biomarker and hub-gene research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, prognostic filtering or risk modeling, PPI-based hub-gene prioritization, diagnostic/prognostic evaluation, clinical association, immune infiltration context, methylation context, and optional tissue or cell validation. Covers five study patterns (signature-first prognostic workflow, hub-gene-first biomarker workflow, hybrid signature-to-hub workflow, immune-context biomarker workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

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Generates complete tumor immune-infiltration-guided bulk-transcriptome diagnostic biomarker and machine-learning research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, immune infiltration estimation, immune-linked module discovery, consensus feature selection, diagnostic modeling, nomogram construction, clinical association, and optional prognostic extension or validation. Covers five study patterns (immune-cell-first diagnostic workflow, immune-module-to-biomarker workflow, consensus-ML biomarker workflow, diagnostic-plus-prognostic hybrid workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, reference literature pack, and self-critical risk review.

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Generates complete dual-disease shared-transcriptome biomarker and hub-gene research designs from a user-provided disease pair and shared-biology direction. Always use this skill whenever a user wants to design, plan, or build a non-oncology two-disease transcriptome study centered on per-disease differential expression, shared-signal intersection or concordance, PPI-based hub-gene prioritization, diagnostic evaluation across both diseases, immune infiltration context, pathway interpretation, and optional orthogonal validation. Covers five study patterns (shared-DEG-first workflow, hub-gene-first shared-biomarker workflow, hybrid shared-biomarker compression workflow, immune-context shared-biomarker workflow, orthogonal validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

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Use when building a weighted gene co-expression network from a bulk expression matrix and a sample group file, filtering variable genes by MAD, identifying co-expression modules with WGCNA, correlating modules with traits, and exporting module-level plots and gene tables. NOT for single-cell RNA-seq, differential expression testing, methylation analysis, or datasets that are too small for WGCNA after quality control.

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Use when performing sample-level dimensionality reduction and visualization on abundance or OTU-style matrices with a companion group file, generating UMAP and/or t-SNE coordinates and plots for group separation assessment. NOT for: differential expression testing, single-cell workflows requiring dedicated embeddings pipelines, or analyses without a sample grouping file.

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Evidence-based medical knowledge and research mentor grounded in the Bian Que tradition. Covers clinical reasoning, diagnostic thinking (望闻问切), pharmacology, pathology, differential diagnosis, medical literature appraisal, and the philosophy of early intervention. Trigger whenever users ask about medicine, clinical science, drugs, disease mechanisms, diagnosis, lab interpretation, treatment comparison, or health sciences. Even without explicit research framing, trigger on any topic touching disease, therapeutics, or clinical decision-making. Part of the AIPOCH Medical Research Skill Hub.

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Use when correcting batch effects in merged bulk expression matrices with sample-level batch metadata while preserving biological group structure and generating before-and-after QC plots. NOT for: single-cell integration, raw FASTQ processing, differential expression without batch labels, or datasets without biological groups.

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Use when building a ceRNA regulatory network from a key gene list by combining bundled miRNA-mRNA and miRNA-lncRNA database files, with flat-file CSV exports and PDF visualization in a single output directory. NOT for: differential expression, single-cell analysis, enrichment analysis, or workflows without a key gene list.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to compute ESTIMATE immune-related microenvironment scores from a bulk expression matrix, generate an ESTIMATE score heatmap, and optionally generate group-wise ESTIMATE score boxplots plus significance tables when a sample group file is supplied. Trigger keywords: ESTIMATE, immune score, stromal score, tumor microenvironment score. NOT for: immune cell deconvolution, single-cell analysis, differential expression, clinical diagnosis.

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Run immune pathway GSVA or ssGSEA analysis from a bulk expression matrix, a sample group file, and a local immune Reactome gene-set table, then export differential pathway results and a heatmap for two-group comparison.

日本語の概要は準備中です。原文の説明を表示しています。

Use when screening differentially expressed genes from a bulk expression matrix between two user-specified groups, producing DEG tables, a volcano plot, and a clustered heatmap. Triggers include DEG analysis, volcano plot, clustered heatmap, limma-based two-group comparison, and case-vs-control screening. NOT for single-cell RNA-seq, multi-group contrasts, count-model workflows such as DESeq2/edgeR, or non-expression omics data.

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Use when identifying stable sample subtypes from bulk expression matrices with ConsensusClusterPlus, including PAC-based model selection and consensus matrix/CDF visualization. NOT for: differential expression analysis, single-cell clustering workflows, or non-expression tables.

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Use when building a sample-level hierarchical clustering dendrogram from a bulk expression matrix and sample annotation table, especially for QC, batch inspection, or sample similarity assessment. Trigger keywords: hierarchical clustering, dendrogram, sample QC, batch inspection, sample similarity. NOT for: differential expression testing, gene clustering heatmaps, single-cell clustering workflows.

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Recommend suitable prompts from 10,000+ Nano Banana Pro image generation prompts based on user needs. Optimized for Nano Banana Pro (Gemini), but prompts also work with Nano Banana 2, Seedream 5.0, GPT Image 1.5, Midjourney, DALL-E, Flux, Stable Diffusion, and any text-to-image AI model. Use this skill when users want to: - Generate images with AI (any model — Nano Banana Pro, Gemini, GPT Image, Seedream, etc.) - Find proven AI image generation prompts and prompt templates - Get prompt recommendations for specific use cases (portraits, products, social media, posters, etc.) - Create illustrations for articles, videos, podcasts, or marketing content - Browse a curated prompt library with sample images - Translate and understand prompt techniques Also available: "ai-image-prompts" skill — a model-agnostic version of this library for universal image generation.

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Findings-first code review workflow for AI coding agents. Use when the user asks to review uncommitted changes, commits in a date range, or a branch compared to the main branch / PR-style diff. Focuses on bugs, regressions, correctness risks, missing tests, security/data-safety issues, and other behavior-changing defects.

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Combine multiple segment detection results into a unified list. Use when you need to merge segments from different detectors, prepare removal lists for video processing, or consolidate detection outputs.

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Calculating powerlifting scores to determine the performance of lifters across different weight classes.

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General workflows and best practices for exoplanet detection and characterization from light curve data. Use when planning an exoplanet analysis pipeline, understanding when to use different methods, or troubleshooting detection issues.

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High-performance numerical computing and machine learning workflows using JAX. Supports array operations, automatic differentiation, JIT compilation, RNN-style scans, map/reduce operations, and gradient computations. Ideal for scientific computing, ML models, and dynamic array transformations.

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Comprehensive clinical laboratory data harmonization for multi-source healthcare analytics. Convert between US conventional and SI units, standardize numeric formats, and clean data quality issues. This skill should be used when you need to harmonize lab values from different sources, convert units for clinical analysis, fix formatting inconsistencies (scientific notation, decimal separators, whitespace), or prepare lab panels for research.

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Calculate the relative contribution of different factors to a response variable using R² decomposition. Use when you need to quantify how much each factor explains the variance of an outcome.

日本語の概要は準備中です。原文の説明を表示しています。