3,211 件 ・ 関連度順
概要と使いどころ
Gene Ontology over-representation analysis using clusterProfiler enrichGO. Use when identifying biological functions enriched in a gene list from differential expression or other analyses. Supports all three ontologies (BP, MF, CC), multiple ID types, and customizable statistical thresholds.
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Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequences. Use when FastQC shows adapter contamination or before alignment of short reads.
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CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering. Use when designing custom sgRNA libraries for knockout, activation, or interference screens.
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Statistical methods for calling hits in CRISPR screens. Covers MAGeCK, BAGEL2, drugZ, and custom approaches for identifying essential and resistance genes. Use when identifying significant genes from screen count data after QC passes.
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Visualize ChIP-seq data using deepTools, Gviz, and ChIPseeker. Create heatmaps, profile plots, and genome browser tracks. Visualize signal around peaks, TSS, or custom regions. Use when visualizing ChIP-seq signal and peaks.
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Creates and configures agent.yaml files, writes SOUL.md personality definitions, and sets up agent directory structures with skills, tools, and knowledge. Use when the user wants to configure an agent, create agent.yaml, write SOUL.md, set up agent directory structure, or customize agent settings.
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Use when the user asks to "triage our comments, DMs, and mentions", "draft replies to this thread", "can we repost this fan post", or "set up inbox SLAs and an escalation path"; produces a ranked triage queue with register detection (sincere / ironic / performative / parasocial, sentiment-inversion table included — "this is so bad" under a comedy register is praise), a commenter taxonomy (troll monitor-only / rager / misguided / unhappy-customer / advocate) with a response-tier ladder and per-channel SLAs, an escalation matrix ending at the crisis path, a moderation ladder plus house rules for owned spaces, and a UGC curation-and-rights mode whose dated permission entries route to the channel registry — every reply is a ranked DRAFT a human posts; nothing is ever auto-sent. Not for launch-window feedback triage — use launch-feedback-synthesizer. 评论私信提及分诊/语域识别/回复草稿/UGC授权
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Map service delivery across frontstage actions, backstage processes, and supporting systems. Use when staff and operations are part of the experience. For the customer-visible layer only, use `experience-map`.
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Compile a structured literature survey on any AI/ML topic. Agent curates a research bundle (taxonomy + sections + bibliography of real papers) from a public anchor resource, then a chosen LLM generates the survey artifact. Output target is a wiki page (markdown), not a one-off HTML — survey lands in `<wiki>/derived/surveys/<slug>.md` with full bibliography rows in `sources.md`. Provider-agnostic (Anthropic/OpenAI/OpenRouter/Fireworks/custom OpenAI-compat). Use when the user asks for a "survey", "literature review", "lit review", or "deep dive" on a technical topic.
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Auto-activate CCS CLI delegation for deterministic tasks. Parses user input, auto-selects optimal profile (glm/kimi/custom) from ~/.ccs/config.json, enhances prompts with context, executes via `ccs {profile} -p "task"` or `ccs {profile}:continue`, and reports results. Triggers on "use ccs [task]" patterns, typo/test/refactor keywords. Excludes complex architecture, security-critical code, performance optimization, breaking changes.
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Configures AWS Site-to-Site VPN: creating an IPsec VPN connection between an on-premises network and a VPC, choosing the target gateway (virtual private gateway, transit gateway, or AWS Cloud WAN), choosing static or dynamic (BGP) routing, sizing tunnel bandwidth (Standard 1.25 Gbps or Large 5 Gbps), connecting many sites through a VPN Concentrator, applying the customer gateway device configuration, making a connection highly available, and monitoring tunnels with CloudWatch. Applicable when the user wants to connect a data center or branch office to AWS over an encrypted tunnel, choose how routes are exchanged, scale throughput, consolidate sites, or diagnose a down tunnel. Routes to the right per-task procedure in references. Not for AWS Direct Connect (its own service), Client VPN for individual remote users, the transit gateway side of a VPN attachment (transitgateway skill), or Route 53 DNS work.
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Configures Amazon Route 53 DNS: public and private records, traffic-steering routing policies, health checks, DNS Firewall, Route 53 Profiles, VPC Resolver (also known as Route 53 Resolver) for hybrid and Outposts networks, and Global Resolver. Applicable when the customer wants to point a hostname at a target, split or fail over traffic across endpoints, monitor an endpoint, block malicious domains, centralize DNS across accounts, or resolve private DNS across a hybrid network. Routes to the right per-task procedure in references. Does not cover CloudFront-specific setup (see the route53-cloudfront skill) or non-DNS networking.
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Configures Amazon Route 53 to route traffic to a CloudFront distribution using a custom domain. Use when setting up DNS alias records, alternate domain names (CNAMEs), ACM certificates for HTTPS, and IPv6 support for CloudFront.
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Retrieves authoritative guidance on Amazon Timestream for InfluxDB across its supported engine variants. Applicable to any InfluxDB-on-AWS request including engine variant and licensing selection, provisioning and IAM, encryption at rest (AWS-owned and customer-managed KMS keys, key policies, and key lifecycle), schema design (tags vs fields, cardinality, HTTP/sensor/metric data modeling), migration from LiveAnalytics, Processing Engine plugins, connectivity (database endpoints and private or public access), and write/query errors.
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Sets up CloudWatch observability for the first time - Omni (CloudWatch Application Observability) and classic CloudWatch. Omni: creating a Space or Domain; access grants (who has access, at what level) and access profiles bounding async alerts, integrations, or agents; instrumenting an app or AI agent with the plain ADOT SDK so traces reach Omni (Python/Node/Java/.NET on EC2/ECS/EKS/Lambda), incl. no-image-rebuild and .NET CoreCLR vars; ingesting Azure telemetry via the CloudWatch agent on an Azure VM or AKS; connecting Slack to a Space; whether GitHub or a custom MCP tool server (HTTP/stdio; API key, bearer, OAuth2) can be connected. CloudWatch: onboarding a service to Application Signals - ADOT auto-instrumentation, the amazon-cloudwatch-observability add-on, monitored service, reporting telemetry, ServiceEvents, CI/CD git/deployment metadata, Terraform/manifest edits. For using what is set up - queries, dashboards, alarms, Omni alerts, X-Ray, synthetics, Dynamic Instrumentation - use aws-observability.
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Performs code upgrades, migrations, and transformations using the AWS Transform (ATX) CLI. Use when upgrading language versions, migrating AWS SDKs, migrating frameworks (Angular, Vue.js, Spring Boot, React), upgrading libraries, optimizing performance, migrating x86 to Graviton, analyzing codebases / generating documentation, or defining custom transformations with natural language. Runs locally on a few repositories or at scale across hundreds via AWS Batch/Fargate.
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Answers questions about Amazon Application Recovery Controller (ARC) Region switch including architecture, plans, execution blocks, workflows, triggers, active/active vs active/passive, cross-account support, recovery time, dashboards, and customer positioning. Applicable when users ask about ARC Region switch adoption, design, or troubleshooting.
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Builds generative AI applications on Amazon Bedrock. Covers model invocation (Converse API, InvokeModel), RAG with Knowledge Bases, Bedrock Agents, Guardrails, and AgentCore (including the Harness managed agent loop). Applies when invoking models, setting up Knowledge Bases, creating agents, applying guardrails, deploying to AgentCore, migrating/porting/converting a Bedrock Agent (including inline agents) to an AgentCore Harness, troubleshooting Bedrock errors (ThrottlingException, AccessDeniedException), or choosing models (Claude, Llama, Nova, Titan). Also for prompt caching, quota and throttling diagnosis, cost tracking, migrating between Claude model generations (4.5 to 4.6 to 4.7), chunking strategies, API selection (Converse vs InvokeModel), guardrail capabilities, and model selection. Also covers AgentCore Payments (x402, microtransactions, Payment Manager, Connector, Instrument, Coinbase CDP, Stripe Privy, paid endpoints, agent payments). NOT for custom model training, Rekognition, or Comprehend.
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Deploy Expo websites and Expo Router API routes to EAS Hosting - export the web bundle, run eas deploy for production and PR preview URLs, manage environment secrets and custom domains, and work within the Cloudflare Workers runtime. Also covers authoring API routes (+api.ts handlers, HTTP methods, request handling, CORS). Use when deploying an Expo web app or API routes, setting up EAS Hosting, or configuring hosting environments and domains. Not for native builds or store releases - use the eas-app-stores skill for those.
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Diagnose Attio REST API failures from status, structured error fields, endpoint contract, and request context without exposing customer data. Use when an Attio request returns 400, 401, 403, 404, 409, 422, 429, or 5xx. Trigger with "Attio error", "Attio request failed", or "debug Attio API".
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Analyze and triage AssemblyAI REST, transcript, Streaming v3, webhook, and LLM Gateway failures without leaking customer content. Use when an integration errors or stalls. Trigger with "AssemblyAI error" or "failed transcript".
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Implement a safe Attio record lifecycle for standard or custom objects, including schema discovery, query, create or assert, update, and delete controls. Use when building record synchronization or CRM write paths. Trigger with "Attio records", "Attio CRUD", or "sync Attio objects".
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Generates customized business agreements for 10 common relationship types with plain English annotations. Use when formalizing a business relationship, creating a partnership agreement, or drafting a service contract from scratch. Trigger with "/agreement-generator" or "create a freelancer agreement".
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Create production-grade agent .md files aligned with the current Anthropic subagent contract. Also validates existing agents against the marketplace compliance rules. Use when building custom subagents, reviewing agent quality, or creating parallel agent architectures for orchestrator skills. Trigger with "/agent-creator", "create an agent", "build a subagent", or "validate my agent". Make sure to use this skill whenever creating agents/*.md files for plugins or standalone use.
日本語の概要は準備中です。原文の説明を表示しています。