「canonical」の検索結果

Scaffold a new PortalJS data portal from a brief. Copies the canonical template from examples/portaljs-catalog and substitutes project tokens. Use when starting a brand-new data portal project from scratch.

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Generates complete reference-grounded single-drug adverse-effect network-pharmacology research designs from a user-provided drug, adverse event, and desired evidence depth. Always use this skill when a user wants to design, plan, or upgrade a conventional network-pharmacology study centered on one fixed drug and one fixed adverse-effect endpoint, using drug-target prediction, adverse-event target collection, overlap analysis, PPI hub prioritization, enrichment interpretation, molecular docking, and optional orthogonal transcriptomic or literature validation. Covers five study patterns (canonical hub-first, cardiotoxicity or electrophysiology-oriented, immune-inflammatory adverse effect, organ-toxicity pathway context, translational validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, dependency/evidence map, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, verified-reference pack, and self-critical risk review.

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Generates complete reference-grounded single-drug adverse-effect network-pharmacology research designs from a user-provided drug, adverse event, and desired evidence depth. Always use this skill when a user wants to design, plan, or upgrade a conventional network-pharmacology study centered on one fixed drug and one fixed adverse-effect endpoint, using drug-target prediction, adverse-event target collection, overlap analysis, PPI hub prioritization, enrichment interpretation, molecular docking, and optional orthogonal transcriptomic or literature validation. Covers five study patterns (canonical hub-first, cardiotoxicity or electrophysiology-oriented, immune-inflammatory adverse effect, organ-toxicity pathway context, translational validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, dependency/evidence map, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, verified-reference pack, and self-critical risk review.

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Matches a user’s biomedical research direction, disease problem, study aim, data modality, and resource constraints to the most relevant recent algorithms and method papers. Always search real recent algorithm literature first, prioritize the last 12 months, expand to 1–3 years only when needed, and add canonical baselines only when necessary. Every formal algorithm recommendation must include the verified primary method paper, plus published downstream papers that actually cite/use the algorithm when such papers are found, with DOI when available. Never fabricate papers, algorithm names, authors, journals, years, DOI, PMID, links, or benchmark claims. If no directly verified algorithm paper is found, say so explicitly.

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Generate cloned narration for the content workspace. Use local IndexTTS2 with the canonical lossless Pluviobyte reference for every local video, voice audition, digital-human narration, and subtitle-ready audio render. Preserve MiniMax only for public-facing articles or tutorials that teach users to connect through the relay service; never use MiniMax for local video production.

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Use when creating Codex, Claude Code, Gemini CLI, Cursor, or AGENTS.md runtime adapters from one canonical agent core. Use whenever a generated repo needs multiple AI runtimes without duplicating instructions.

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Use when designing how one canonical agent core runs across Codex, Claude Code, Gemini CLI, Cursor, and AGENTS.md-compatible tools.

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Recover the first public timestamp and canonical major coverage for a newsjacking signal, then decide whether newer coverage is the same story, a different story, or a materially new development.

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Select QA-approved canonical intent cells into a versioned AI-visibility tracking panel with partitions, variants, lanes, surfaces, locales, repetitions, separate exposure and priority weights, randomization, uncertainty, refresh rules, and campaign controls. Use after prompt QA or when revising an existing panel.

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Turn an approved measurement charter, ICPs, and buyer jobs into a budget-aware prompt coverage blueprint across proximity bands, aided status, information acts, journey states, roles, locales, evidence grades, partitions, and measurement lanes. Use before prompt wording to define required, optional, and prohibited canonical intent cells.

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Requirements authoring guide for BRD and PRD across Discover, Define, and Govern with canonical templates and handoff contracts

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Canonical documentation capability for audit, drift, validate, and author modes in hve-core.

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Design Thinking coaching foundation knowledge: coach identity and philosophy, quality and fidelity constraints, method sequencing, coaching state schema, and the canonical deck workflow

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Generate customer-card PowerPoint content YAML from Design Thinking canonical artifacts and build using the shared PowerPoint skill pipeline

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Use when implementing a new Spark expression in DataFusion Comet. Walks through cloning latest Spark master to study the canonical implementation, checking the upstream datafusion-spark crate before writing native code, building the Comet serde and Rust wire-up from the contributor guide, then running audit-comet-expression to drive a test-coverage iteration loop.

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Canonical short-form-ad audio mix in one FFmpeg pass. VO loudnorm + 3.0× per-clip + 2.0× mix, music 0.13 base + apad+afade, sidechain compress 20:1 @ 0.01, climax line +20%, optional video-to-music duration sync. Replaces the reactive multi-round tuning that cost v03 6+ passes.

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Maintain a brand kit — the canonical brand context an ad or content pipeline reads (positioning, audience, voice, standing instructions, brand-type, value-props, colors), plus manage the product list and attach product photos. Use when someone says "update my brand kit", "set my brand voice/audience", "add a product to my brand", or hands you a folder of product shots to attach. Platform-agnostic: it teaches the field model, partial-update/clear semantics, override behavior, caps and validation, and the hero-image and product-matching rules — independent of any specific backend.

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Visualises RNA-modification data with transcript-feature metagene plots (Guitar GuitarPlot; MetaPlotR; deepTools computeMatrix scale-regions), peak-centred heatmaps (ComplexHeatmap; deepTools plotHeatmap), IP-vs-input paired browser tracks (log2 IP/input bigWig via deepTools bamCompare; pyGenomeTracks; Gviz; IGV/UCSC track hubs), DRACH sequence-logo plots (ggseqlogo; MEME), feature-distribution stacked bars, and volcano/MA plots for differential modification. Establishes stop-codon enrichment in the metagene plot as the biological QC anchor for any MeRIP dataset (Dominissini 2012; Meyer 2012). Use when producing the canonical metagene plot with stop-codon enrichment as a QC anchor, building paired IP/input genome-browser tracks at single-locus resolution, plotting peak-centred heatmaps clustered by condition, summarising peak distribution across transcript features, generating DRACH motif logos as sanity checks, rendering volcano plots of differential m6A, or reproducing the stop-codon enrichment plot.

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Defines cell populations in flow and spectral cytometry through manual gates (rectangle, polygon, quadrant, boolean) and reproducible automated gating (openCyto gating templates, flowDensity data-driven thresholds, flowClust model-based gates), organized as a hierarchical GatingSet (flowWorkspace) and round-tripped with FlowJo via CytoML. Covers the canonical gate order (time -> debris -> singlets -> live -> lineage), FMO-vs-isotype boundary setting, gate-order dependence and recompute semantics, rare-event/MRD gating, and per-population statistics. Use when building a gating strategy, automating a manual FlowJo scheme across samples, choosing manual vs data-driven gates, or extracting population frequencies.

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Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.

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[Deprecated] Use when building frontend Web apps that talk to CloudBase Relational Database via @cloudbase/js-sdk – provides the canonical init pattern so you can then use Supabase-style queries from the browser. New environments should use PostgreSQL with app.rdb() — see postgresql-development skill instead.

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[Deprecated] This is the required documentation for agents operating on the CloudBase Relational Database through MCP. It defines the canonical SQL management flow with `queryMysqlDatabase`, `manageMysqlDatabase`, `queryPermissions`, and `managePermissions`, including destroy flow, async status checks, safe query execution, schema initialization, and permission updates. MySQL provisioning is no longer available through MCP; new environments should use PostgreSQL — see postgresql-development skill instead.

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Generate engaging, localized App Store release notes (What's New) from git log, bullet points, or free text using canonical metadata under `./metadata`. Optionally pairs with promotional text updates.

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Run an offline ASO audit on canonical App Store metadata under `./metadata` and surface keyword gaps using Astro MCP. Use after pulling metadata with `asc metadata pull`.

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