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概要と使いどころ
Investigate fast-agent session and history files to diagnose issues. Use when a session ended unexpectedly, when debugging tool loops, when correlating sub-agent traces with main sessions, or when analyzing conversation flow and timing. Covers session.json metadata, history JSON format, message structure, tool call/result correlation, and common failure patterns.
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Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create visualizations of big data, or build ML pipelines that do not fit in memory.
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Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
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Property-based testing with fast-check (TypeScript/JavaScript) and Hypothesis (Python). Generate test cases automatically, find edge cases, and test mathematical properties. Use when user mentions property-based testing, fast-check, Hypothesis, generating test data, QuickCheck-style testing, or finding edge cases automatically.
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Primary retained Python toolkit for molecular biology sequence work. Preferred for sequence manipulation, FASTA/FASTQ/GenBank parsing, Bio.Entrez, BLAST workflows, alignments, structures, and phylogenetics. For biological database evidence lookup, use bio-database-evidence. For single-cell workflows use scanpy. For direct literature REST API, use pubmed-database.
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Generate multiple sequence alignments (MSAs) for protein sequences using the ColabFold MSA-Search NIM. Use for homolog search, UniRef30/ColabFold env searches, A3M or FASTA alignments, paired MSA search for complexes, PDB70 structural templates, hosted NVIDIA API calls, or local Docker deployment. For local deployment, download the databases in parallel with aria2c and launch via NIM_MODEL_NAME (the recommended default fast path, ~14 min vs over 80 min for the built-in downloader); a plain docker run uses the slow built-in downloader.
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Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger this whenever the user provides a protein sequence or FASTA file and asks to find homologues, sequence matches, or wants to infer protein function based on sequence similarity, but not when the user wants to infer protein function based on structural similarity.
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Deploy Python (Flask/Django/FastAPI) code to Azure App Service Linux. WHEN: "Flask App Service", "Django App Service", "FastAPI App Service", "deploy Python to App Service". DO NOT USE FOR: Container Apps, Functions, non-Python, Terraform/Bicep/IaC, full infra — use azure-prepare.
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Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequences. Use when FastQC shows adapter contamination or before alignment of short reads.
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Generate and interpret quality reports from FASTQ files using FastQC and MultiQC. Assess per-base quality, adapter content, GC bias, duplication levels, and overrepresented sequences. Use when performing initial QC on raw sequencing data or validating preprocessing results.
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Handle paired-end FASTQ files (R1/R2) using Biopython. Use when working with Illumina paired reads, synchronizing pairs, interleaving/deinterleaving, or filtering paired data.
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Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.
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Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
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Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.
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Creates and deploys Node.js HTTP web applications on AWS Lambda Web Functions. Guides users through building web apps and APIs with Express, Fastify, or Hono, packaging, deploying via the aws lambda-web CLI, and iterating. Triggers when user wants to deploy a website or web app to AWS as serverless, deploy a Node.js HTTP server to AWS, build a serverless website or API with Node.js, deploy Express/Hono/Fastify apps, set up multi-region HTTP endpoints, connect a Node.js web app to private VPC resources, or explicitly mentions Lambda Web Functions. Does NOT trigger for non-Node.js runtimes, event-driven patterns (SQS, Kinesis, S3 events), or container deployments.
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Guided journey from a working codebase grown slow and tangled to one measurably fast, cleanly bounded, and readable. Orchestrates eight skills phase by phase - working-with-legacy-code, clean-architecture, software-design-philosophy, refactoring-patterns, system-design, ddia-systems, release-it, pragmatic-programmer - every phase carries its method inline so it runs standalone, asking the user questions at every decision point and recording results in the project docs/ folder (PERFORMANCE.md, ARCHITECTURE.md, ARCHITECTURE-OPTIMIZATION-PLAN.md) so the journey resumes across sessions. Use when the user wants to make an app faster, untangle drifted boundaries, fix slow endpoints and queries, or says 'it works but it is slow and getting worse'. For an untested prototype, improve-code-quality; for an aged codebase you fear to touch, remove-technical-debt; for greenfield structure, design-code-architecture; for marketing-site page speed, improve-website. For one framework in isolation, invoke that skill directly.
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Use when analyzing FASTQC quality reports from sequencing data, identifying quality issues in NGS datasets, or troubleshooting sequencing problems. Interprets quality metrics and provides actionable recommendations for RNA-seq, DNA-seq, and ChIP-seq data.
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Use Biopython to read/write/convert biological sequence files (FASTA/GenBank/FASTQ, etc.) and perform basic sequence operations; use when you need reliable sequence I/O, lightweight sequence manipulation, or scalable processing of large sequence datasets.
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Use BEFORE reading any data file that could be large (CSV/TSV, Parquet, HDF5, FITS, NetCDF, NDJSON, genomics FASTQ/FASTA/VCF/BAM, GRIB, ROOT, or big text/simulation logs like VASP OUTCAR). Returns a compact memory pointer — header/schema/shape/sample/key numbers — by introspection and sampling in bounded memory, so you never load a file bigger than the context window into the model. Reference data via the pointer; read specific ranges deterministically.
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Use when Codex feels slow or bloated, when local sessions/logs/worktrees/config have grown over time, or when a user wants safe maintenance for Codex Desktop/CLI state. Provides a read-only report by default, backs up before applying changes, archives instead of deleting, normalizes Windows extended paths, prunes dead config projects, rotates large logs, and moves stale worktrees.
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Deploy Python (Flask/Django/FastAPI) code to Azure App Service Linux. WHEN: "Flask App Service", "Django App Service", "FastAPI App Service", "deploy Python to App Service". DO NOT USE FOR: Container Apps, Functions, non-Python, Terraform/Bicep/IaC, full infra — use azure-prepare.
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Fast non-interactive briefing before any meeting — auto-detects your next calendar event, pulls relationship history, surfaces open commitments, and produces a one-page brief in under 30 seconds. Use this whenever the user says "brief me", "give me a quick brief", "what's coming up", "background on my next call", "who am I meeting next", "brief me on Sarah", "I have a call in 10 min", "quick rundown", or right before walking into a meeting. Different from /minutes-prep — brief is the fast hook-fireable version that doesn't ask questions and doesn't set goals. Use brief when speed matters; use prep when the user wants to think hard about goals first.
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End-to-end Codex-native Amazon FBA research workflow using LaunchFast MCP. Use when the user wants a single report covering product research, IP risk, supplier sourcing, and PPC keyword intelligence. Requires `research_products`, `ip_check_manage`, `supplier_research`, and `amazon_keyword_research`.
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Mobile/web build pipeline: fastlane-first local builds, store submission, pre-submission checklists. Triggers: app, mobile, store submission, deploy app, fastlane, expo, react native, flutter.
日本語の概要は準備中です。原文の説明を表示しています。