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VS-Enhanced Research Question Refiner - Prevents Mode Collapse and derives differentiated research questions Enhanced VS 3-Phase process: Modal question avoidance, alternatives presentation, differentiated RQ recommendation Use when: refining research ideas, formulating research questions, clarifying scope Triggers: research question, 연구 질문, PICO, SPIDER, research idea

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Complete survival analysis library in Python. Handles right-censored data, Kaplan-Meier curves, and Cox regression. Standard for clinical trial analysis and epidemiology.

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Classical end-to-end empirical analysis workflow in the traditional Stata ecosystem — native Stata + reghdfe + ivreg2 + csdid + did_imputation + eventstudyinteract + sdid + rdrobust + rddensity + synth + synth_runner + psmatch2 + teffects + ebalance + coefplot + esttab + asdoc + binscatter. **Defaults to economics empirical-paper style** (AER / QJE / AEJ) — every run produces a publication-ready output set with a multi-column regression table (M1→M6 progressive controls/FE) as the centerpiece, plus Table 1 (descriptives), mechanism / heterogeneity / robustness tables, and event-study + coefficient + trend figures. Covers the full 8-step Stata pipeline an applied economist runs on every paper — (1) data import & cleaning (use/import, destring, misstable, duplicates, merge assert), (2) variable construction (gen/egen/winsor2/xtile/xtset with L./F./D.), (3) descriptive statistics & Table 1 (tabstat/balancetable/asdoc), (4) classical diagnostic tests (sktest/swilk/hettest/imtest/xtserial/xttest3/vif/dfuller/kpss/hausman/estat overid), (5) baseline modeling (reg/xtreg/reghdfe/ivreg2/ivregress/csdid/did_imputation/eventstudyinteract/sdid/rdrobust/synth/psmatch2/teffects/heckman/qreg/ppmlhdfe), (6) robustness battery (bacondecomp/honestdid/rwolf/ritest/wildbootstrap/oster), (7) further analysis (subgroup/triple-diff/interactions/medsem/marginsplot/binscatter by group), (8) publication-ready tables & figures (esttab/outreg2/estout/coefplot/marginsplot/rdplot/twoway combined). **Also covers two parallel domain modes that share the same 8-step scaffolding** — **Mode A — Epidemiology / public health** (target-trial emulation, IPTW + g-formula + TMLE doubly-robust triplet via `teffects ipw` / `teffects ipwra` / `teffects aipw` / `eltmle`, Mendelian randomization via `mrrobust` (IVW / Egger / weighted median) and `mregger` / `mrpresso`, KM / Cox / AFT / RMST survival via `sts` / `stcox` / `streg` / `strmst2`, E-value sensitivity via `evalue` (Linden-Mathur), principal stratification — STROBE / TRIPOD reporting), and **Mode B — ML causal inference** (DML via `ddml` / `pdslasso`, S/T/X/R/DR meta-learners via `crforest` and `ddml interactive`, causal forest via `crforest` / `cforest`, BART/BCF via `bart` / `bartCause`-style externals, CATE distribution + policy tree via `crforest`, off-policy evaluation, conformal causal externals, fairness audit, DAG learning via `pcalg` / external Python callouts). Use when the user asks for a complete Stata empirical analysis, wants a reproducible .do-file pipeline, needs a Stata counterpart to the Python StatsPAI / Full-empirical-analysis-skill, or names a specific Stata step in isolation ("run reghdfe with two-way clustering", "csdid event study", "winsor2 at 1%", "esttab to LaTeX", "coefplot with CI", "ivreg2 weak-IV test", "synth_runner placebos", "teffects psmatch balance check"). Mode A triggers on "target trial emulation Stata", "teffects ipw aipw", "eltmle", "mrrobust", "mregger weighted median", "stcox AFT survival", "strmst2", "evalue Stata", "STROBE Stata", "公共健康 Stata", "流行病学 Stata". Mode B triggers on "ddml Stata", "pdslasso", "crforest causal forest Stata", "policy tree Stata", "因果机器学习 Stata".

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Classical end-to-end empirical analysis workflow in the modern tidyverse + econometrics R ecosystem — dplyr + tidyr + haven + fixest + sandwich + lmtest + clubSandwich + AER + ivreg + did + bacondecomp + HonestDiD + eventstudyr + rdrobust + rddensity + Synth + gsynth + synthdid + MatchIt + WeightIt + cobalt + ebal + grf + DoubleML + mediation + marginaleffects + modelsummary + kableExtra + gt + ggplot2 + ggpubr + cowplot + binsreg. **Defaults to economics empirical-paper style** (AER / QJE / AEJ) — every run produces a publication-ready output set with a multi-column regression table (M1→M6 progressive controls/FE) as the centerpiece, plus Table 1 (descriptives), mechanism / heterogeneity / robustness tables, and event-study + coefficient + trend figures. Covers the full 8-step R pipeline an applied economist runs on every paper — (1) data import & cleaning (read_dta/read_csv, naniar, janitor, validate-merges), (2) variable construction (mutate/across/winsorize/group_by + lag/lead with dplyr), (3) descriptive statistics & Table 1 (gtsummary, modelsummary::datasummary, tableone), (4) classical diagnostic tests (shapiro/jarque.bera.test/bptest/dwtest/bgtest/vif/adf.test/kpss.test/Hausman), (5) baseline modeling (fixest::feols, ivreg, did::att_gt, eventstudyr, sun_ab, did_imputation, synthdid, rdrobust, MatchIt, WeightIt, grf::causal_forest, DoubleML, mediation), (6) robustness battery (modelsummary stack, clubSandwich CRSE, fwildclusterboot, ri2, robomit Oster, bacondecomp, HonestDiD), (7) further analysis (interactions + marginaleffects, mediation::mediate, gsem via lavaan, dose-response splines, grf CATE), (8) publication-ready tables & figures (modelsummary, kableExtra, gt, stargazer, texreg, flextable to LaTeX/Word/HTML; ggplot2 + ggpubr + cowplot + binsreg + iplot for figures). **Also covers two parallel domain modes that share the same 8-step scaffolding** — **Mode A — Epidemiology / public health** (target-trial emulation, IPTW + g-formula + TMLE doubly-robust triplet via `WeightIt` / `gfoRmula` / `tmle` / `ltmle`, Mendelian randomization via `MendelianRandomization` / `TwoSampleMR` / `MRPRESSO`, KM / Cox / AFT / RMST survival via `survival` / `survminer` / `flexsurv`, E-value sensitivity via `EValue`, principal stratification — STROBE / TRIPOD reporting), and **Mode B — ML causal inference** (DML via `DoubleML`, S/T/X/R/DR meta-learners via `causalweight` / `grf`, causal forest via `grf::causal_forest`, BART/BCF via `bartCause` / `bcf`, matrix completion via `MCPanel`, CATE distribution + policy tree via `policytree`, off-policy evaluation, conformal causal via `conformalInference` / `cfcausal`, fairness audit via `fairmodels`, DAG learning via `pcalg` / `bnlearn` / LLM-assisted). Use when the user asks for a complete R empirical analysis, wants a tidyverse-style reproducible R script / Quarto workflow, prefers fixest over reghdfe, needs the R counterpart to StatsPAI / 00.1 / 00.2, or names a specific R step in isolation ("feols with cluster", "MatchIt nearest neighbor", "bacondecomp in R", "gtsummary table 1", "modelsummary to Word"). Mode A triggers on "target trial emulation R", "tmle ltmle", "MendelianRandomization", "TwoSampleMR", "MRPRESSO", "survival cox AFT", "STROBE R", "EValue R", "公共健康 R", "流行病学 R". Mode B triggers on "DoubleML R", "grf causal forest", "policytree", "bartCause bcf", "conformal causal R", "fairmodels", "pcalg NOTEARS", "因果机器学习 R".

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Orchestrates end-to-end autonomous AI research projects using a two-loop architecture. The inner loop runs rapid experiment iterations with clear optimization targets. The outer loop synthesizes results, identifies patterns, and steers research direction. Routes to domain-specific skills for execution, supports continuous agent operation via Claude Code /loop and OpenClaw heartbeat, and produces research presentations and papers. Use when starting a research project, running autonomous experiments, or managing a multi-hypothesis research effort.

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Autonomous performance optimization: research, PoC, benchmark, implement, review, PR

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渗透速查与Payload — 快速Payload家族、绕过提醒、验证顺序、常见测试卡片，适用于已知测试方向后快速查找

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Plan an MVP-mode phase — captures an "As a / I want to / So that" user story, runs SPIDR splitting, then delegates to plan-phase

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Use for NVIDIA-related requests where an NVIDIA skill might help, even if the user did not ask for a skill. Trigger on NVIDIA products, hardware, software, SDKs, GPUs, Jetson/JetPack/L4T/BSP/SDK Manager/driver/flashing/setup, CUDA, NIM, NeMo, Omniverse/OpenUSD/SimReady, Isaac, RAPIDS/cuDF, cuPyNumeric, cuOpt, Dynamo, Holoscan, TensorRT, DeepStream, VSS, TAO, NGC/NVCF. Do not use for generic non-NVIDIA route, optimize, deploy, AI, video, data, or infrastructure tasks.

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Use this skill to enumerate host↔DPU DOCA comch (formerly Comm Channel) servers and connections via the shipped doca_comm_channel_admin binary — listing comch-capable devices and decoding the per-device server / connection table (server name, PID, in-use / max, PCIe address). The shipped binary is a SINGLE-SHOT SCAN-AND-PRINT tool with no registered arguments — NO list / inspect / drain / restart subcommands; one inventory pass over every comch-capable doca_dev on this side. Channel reset / drain / restart go to doca-comch (program side), doca-setup / doca-hardware-safety (driver reload), or BFB / RShim — NOT to this binary. Trigger on phrasings like "list comch servers", "which channels are active on this BlueField", or "verify admin tool sees same channel as program." Refuse and route elsewhere for the comch programming API, library install, protocol design, channel reset, or general orientation.

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Sysinternals DebugView CLI (DbgViewCli) for capturing and analyzing usermode and kernel-mode Windows debug output from the command line. USE FOR: capturing OutputDebugString output, kernel DbgPrint/KdPrint capture, boot-time debug logging, remote debug monitoring, filtering debug output by PID or process name, crash dump analysis, automated debug capture with bounded execution. DO NOT USE FOR: non-Windows platforms, application-level logging frameworks (log4j, serilog), Azure Monitor or cloud telemetry, ETW tracing (use WPR/xperf instead), user-mode crash dumps (use WinDbg). Triggers: "debug output", "DbgView", "DebugView", "kernel debug", "capture debug logs", "boot logging", "OutputDebugString", "DbgPrint", "KdPrint", "remote debug monitor", "debug capture CLI".

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Assign pathogen lineages and track variants using Nextclade and pangolin for viral surveillance. Monitor variant prevalence and identify emerging variants of concern. Use when classifying viral sequences, tracking lineage dynamics, or monitoring for variants of concern.

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Perform multi-locus sequence typing (MLST), core genome MLST, and SNP-based strain typing for bacterial isolate characterization using mlst and chewBBACA. Use when identifying strain types, tracking outbreak clones, or characterizing bacterial isolates.

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Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime and BEAST2 for outbreak analysis. Estimate divergence times, molecular clock rates, and ancestral states. Use when dating outbreak origins, estimating transmission rates, or building time-calibrated trees.

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Set up iterative design-to-code development loop with Anima SDK. Use when rapidly iterating on Figma-to-code output, comparing framework outputs, or building a local preview server for generated components. Trigger with: "anima local dev", "anima dev loop", "anima preview", "anima iteration".

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Run a structured 5-day process to prototype, test, and validate product ideas with real users. Use when the user mentions "design sprint", "validate before we build", "rapid prototype", "test with users", or "should we build this". Also trigger when a team is stuck in endless debate over a high-stakes product decision, or wants to de-risk a costly idea before investing in development. Covers mapping, sketching, deciding, prototyping, and testing across Monday-Friday. For ongoing experimentation and MVPs, see lean-startup. For customer job analysis, see jobs-to-be-done. For non-leading user interviews, see mom-test.

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Apply lean thinking to UX: hypothesis-driven design, collaborative sketching, and rapid experiments instead of heavy deliverables. Use when the user mentions "Lean UX", "design hypothesis", "outcome over output", "design studio method", "assumption mapping", "lightweight research", "too much design documentation", or "get the team designing together". Also trigger when reducing design-documentation overhead, getting cross-functional teams to co-design, or running fast usability experiments. Covers hypothesis statements, MVPs for UX, and cross-functional collaboration. For Build-Measure-Learn, see lean-startup. For usability audits, see ux-heuristics.

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Discover what customers truly need by analyzing the "job" they hire your product to do. Use when the user mentions "customer discovery", "why customers churn", "what job does this solve", "competing against luck", "product-market fit", "switching behavior", "milkshake moment", or "functional vs emotional jobs". Also trigger when investigating why users choose competitors, designing features around real customer needs, or reframing a value proposition. Covers JTBD interviews, competition analysis, and jobs-oriented roadmaps. For product positioning, see obviously-awesome. For rapid validation, see design-sprint. For non-leading interview technique, see mom-test.

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Talk to customers without leading them using Mom Test rules: discuss their life not your idea, ask about specifics in the past, and talk less. Use when the user mentions "customer interviews", "validate my idea", "users say they want it but dont buy", "leading questions", "The Mom Test", "customer feedback bias", or "interview script". Also trigger when preparing user-research questions, interpreting ambiguous feedback, or designing customer-discovery that avoids false positives. Covers commitment and advancement, avoiding compliments, and extracting signal from noise. For product-market fit, see jobs-to-be-done. For rapid prototype testing, see design-sprint.

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Create professional presentations using the Pyramid Principle methodology. Supports PPTX generation, Marp/Reveal.js Markdown slides, chart creation, speaker notes, and self-evaluation rubrics. Minimal intake form to rapid output workflow.

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Automatically find references for academic paper Markdown files. Reads full paper text, identifies each knowledge point requiring citation (epidemiological data, mechanism descriptions, existing research conclusions, etc.), searches PubMed for 3-5 most relevant articles per kn...

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Plans confounder control, variable adjustment logic, and bias mitigation strategies at the protocol stage for clinical, epidemiologic, translational, observational, and biomarker studies. Always use this skill when a user needs to identify major confounders, decide which variables should or should not be adjusted for, compare matching/stratification/weighting approaches, anticipate selection or measurement bias, or pressure-test a study design before execution. Focus on bias sensing, causal structure awareness, variable-role classification, and critical design review rather than generic statistical advice.

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Generates complete NHANES-style cross-sectional epidemiology + retrospective clinical validation research designs from a user-provided disease and biomarker direction. Always use this skill whenever a user wants to design, plan, or build a population-level biomarker association study using NHANES or similar survey datasets, especially when the article logic includes disease definition, biomarker formula derivation, multivariable logistic regression, restricted cubic spline analysis, subgroup stability testing, and a secondary hospital-based retrospective validation cohort. Covers five study patterns (cross-sectional association, dose-response / RCS, subgroup-stability, NHANES + retrospective validation, preliminary screening-performance) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

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Rapidly maps the evidence landscape around a medical topic by organizing major research streams, target populations, endpoints, methods, evidence density, and thin areas. Use this skill BEFORE medical-research-gap-finder — it provides the structured landscape that makes formal gap analysis more rigorous. Do not use for formal gap identification, study design, or protocol planning directly.

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