Detects TAD boundaries from balanced Hi-C contact matrices via the diamond-window insulation score (cooltools insulation) and HiCExplorer hicFindTADs, returning a continuous log2 insulation track, valley-prominence boundary_strength, and Li/Otsu-thresholded is_boundary flags across a list of window sizes. Covers the multi-scale window sweep (sub-TAD to compartment-domain), why the boundary is reproducible but the domain partition is not, cross-condition comparison via differential SCORE not differential partition, and the insulation-vs-compartment orthogonality. Use when calling TADs or domain boundaries, computing insulation scores, choosing a window size, ranking boundary strength, comparing boundaries across conditions, or annotating CTCF-backed boundaries; route domain rendering to hic-visualization and boundary-feature overlap to genome-intervals.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Rank and prioritize neoantigen/epitope candidates by likely T-cell response using NeoFox feature annotation, PRIME2.0, BigMHC-IM, the Łuksza/Balachandran fitness model (agretopicity + foreignness), and pVACtools tiering. Encodes the field's hard truths that immunogenicity is the least-solved layer (dedicated scores ~AUROC 0.6-0.7, modest PPV), that scores are valid only for RANKING within one patient (never absolute go/no-go or cross-patient), that DAI has anchor-inflation and WT-denominator traps, and that stacking weak correlated scores into one number is a red flag. Use when ordering a candidate list for a vaccine. Binding lives in mhc-binding-prediction; calling in neoantigen-prediction.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Detects acquired antimicrobial-resistance determinants and chromosomal point-mutation resistance in bacterial assemblies using AMRFinderPlus, ResFinder 4.0 (acquired + PointFinder), CARD-RGI, abritAMR, staramr, and species-specific callers (TB-Profiler, Mykrobe). Harmonises cross-tool output via hAMRonization, contextualises determinants with mobile-genetic-element annotation (MOB-suite, PlasmidFinder, MobileElementFinder, ICEberg), predicts phenotype against EUCAST or CLSI breakpoints, and translates calls into WHO GLASS reporting categories. Use when screening clinical or surveillance isolates for AMR, distinguishing acquired vs intrinsic vs point-mutation resistance, calling rpoB / katG / pncA / gyrA / mgrB mutations, reconciling AMRFinderPlus vs RGI vs ResFinder disagreement, contextualising carbapenemases or mcr alleles on plasmids, predicting susceptibility from genotype against the WHO Mtb 2nd-edition catalogue, or building a hAMRonized multi-lab AMR surveillance pipeline.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Analyzes alternative splicing from PacBio Iso-Seq (HiFi, Kinnex/MAS-Iso-seq) and Oxford Nanopore (direct cDNA, direct RNA, R10.4.1+) long-read RNA-seq with full-isoform resolution. Tools include FLAIR (correct/collapse/quantify/diffSplice for PacBio + ONT), IsoQuant (de-novo or annotation-guided isoform discovery 2024 SOTA), Bambu (annotation-aware Bayesian discovery + quantification with Novel Discovery Rate), SQANTI3 (isoform classification: FSM/ISM/NIC/NNC + artifact flags), rMATS-long (event calling on long-read isoforms), and minimap2 (-ax splice:hq for HiFi; -ax splice -k14 for ONT cDNA; add -uf only for direct RNA or stranded cDNA preps). Solves microexon detection, recursive splicing, complex multi-exon isoforms, and DTU without transcript-quantification uncertainty. Use when short-read AS limitations (anchor length, complex isoforms, microexons, recursive splicing, transcript ambiguity) demand full-isoform resolution.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Build private, on-device AI features on iPhone, iPad, and Mac with Foundation Models, Core ML, MLX Swift, or llama.cpp. Use when choosing an Apple-local model runtime, building an Apple Intelligence chatbot or tool-calling feature, running an LLM on Apple Silicon, converting or compressing a Python model for Core ML, or comparing on-device inference backends. For Swift Core ML loading and prediction code, use the coreml skill.
日本語の概要は準備中です。原文の説明を表示しています。
dpearson2699/swift-ios-skills☆ 1,1922026年8月1日 更新
Read BEFORE writing any code that builds or simulates OFDM systems. The default MATLAB patterns for OFDM (e.g., direct ifft/fft, awgn with 0 dBW power, missing symOffset) produce subtly incorrect results — always use ofdmmod/ofdmdemod instead of direct IFFT/FFT. This skill specifies the correct calling conventions for ofdmmod, ofdmdemod, ofdmChannelResponse, ofdmEqualize, and critical anti-patterns that must be avoided. Use when building OFDM transmitters or receivers, allocating subcarriers and guard bands, inserting pilots, computing SNR for OFDM, configuring fading channels (Rayleigh/Rician), estimating and equalizing channels, implementing timing and frequency synchronization, adding LDPC coding, designing resource grids, or setting up OFDM link simulations.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1572026年10月9日 更新
Read BEFORE writing any code that adds Additive White Gaussian Noise (AWGN) to signals and converts between SNR, Eb/No, Es/No, and per-subcarrier SNR for communications simulations, using awgn(), convertSNR(), berawgn(). The default MATLAB patterns for AWGN (e.g., 'measured' option, manual SNR formulas) produce subtly incorrect results. This skill specifies the correct calling conventions, required function usage, and critical anti-patterns that must be avoided.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1572026年10月9日 更新
Use when importing or exporting vehicle data from/to log files (MDF/MF4/DAT, BLF, ASC/TXT), decoding CAN/CAN FD/LIN messages to signals via DBC, ARXML, or LDF databases, writing timetable data to MDF or BLF files, or calling blfread, blfinfo, blfwrite, mdfRead, mdfWrite, mdfCreate, mdfInfo, canSignalImport, canMessageImport, canMessageTimetable, canFDMessageTimetable, canSignalTimetable, or linMessageTimetable.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1572026年10月9日 更新
CloudBase function runtime guide for building, deploying, and debugging your own Event Functions or HTTP Functions. This skill should be used when users need application runtime code on CloudBase, not when they are merely calling CloudBase official platform APIs.
日本語の概要は準備中です。原文の説明を表示しています。
TencentCloudBase/CloudBase-AI-Toolkit☆ 1,1362026年10月13日 更新
epigraHMM provides a set of tools for the analysis of epigenomic data based on hidden Markov Models. It contains two separate peak callers, one for consensus peaks from biological or technical replicates, and one for differential peaks from multi-replicate multi-condition experiments. In differential peak calling, epigraHMM provides window-specific posterior probabilities associated with every possible combinatorial pattern of read enrichment across conditions.
日本語の概要は準備中です。原文の説明を表示しています。
bioMate-AI/biomate-bioconductor-kb☆ 8042026年6月21日 更新
On-device LLM integration using Apple's Foundation Models framework. Use when implementing AI text generation, structured output, or tool calling.
日本語の概要は準備中です。原文の説明を表示しています。
rshankras/claude-code-apple-skills☆ 7912026年7月24日 更新
Expert knowledge for Azure AI Custom Vision development including best practices, decision making, limits & quotas, security, integrations & coding patterns, and deployment. Use when exporting Custom Vision models, calling prediction APIs, using ONNX/TensorFlow, managing CMK/RBAC, or Smart Labeler, and other Azure AI Custom Vision related development tasks. Not for Azure AI Vision (use azure-ai-vision), Azure AI services (use microsoft-foundry-tools), Azure Machine Learning (use azure-machine-learning), Azure AI Foundry Local (use microsoft-foundry-local).
日本語の概要は準備中です。原文の説明を表示しています。
MicrosoftDocs/Agent-Skills☆ 7792026年10月11日 更新
Find the papers that answer a research query in Firecrawl's research paper index — a corpus of paper abstracts whose largest share is biomedical and life-science literature (PubMed, bioRxiv, medRxiv), alongside arXiv preprints in CS, physics, and math — using semantic search, semantic and structural expansion, and in-body verification. Use this skill for literature-finding and paper-retrieval tasks of any kind, including clinical, biomedical, drug, gene, disease, and other life-science questions, whether the answer is a single paper or a full multi-paper set. The index is reached only through the `firecrawl_research_*` MCP tools or the `firecrawl research` CLI subcommands. Calling `firecrawl_search` with its `categories` option set to `["research"]` is a different feature — it filters ordinary web search to research-affiliated websites (the list includes PubMed, bioRxiv, medRxiv, arXiv, and publisher sites) and returns page results from them, without querying the paper records in this index.
日本語の概要は準備中です。原文の説明を表示しています。
firecrawl/cli☆ 6492026年10月13日 更新
Guides technology selection and implementation of AI and ML features in .NET 8+ applications using ML.NET, Microsoft.Extensions.AI (MEAI), Microsoft Agent Framework (MAF), GitHub Copilot SDK, ONNX Runtime, and OllamaSharp. Covers the full spectrum from classic ML through modern LLM orchestration to local inference. Use when adding classification, regression, clustering, anomaly detection, recommendation, LLM integration (text generation, summarization, reasoning), RAG pipelines with vector search, agentic workflows with tool calling, Copilot extensions, or custom model inference via ONNX Runtime to a .NET project. DO NOT USE FOR projects targeting .NET Framework (requires .NET 8+), the task is pure data engineering or ETL with no ML/AI component, or the project needs a custom deep learning training loop (use Python with PyTorch/TensorFlow, then export to ONNX for .NET inference).
日本語の概要は準備中です。原文の説明を表示しています。
managedcode/dotnet-skills☆ 4862026年10月13日 更新
This skill should be used when working with Vercel AI SDK, AI Gateway, streamText, generateText, generateObject, streamObject, tool calling, or AI SDK providers. Also relevant for "ai-sdk", "@ai-sdk/*" packages, or questions about AI SDK patterns, configuration, and best practices.
日本語の概要は準備中です。原文の説明を表示しています。
malob/nix-config☆ 4632026年10月11日 更新
Run AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation. Models: FLUX, Veo, Gemini, Grok, Claude, Seedance, OmniHuman, Tavily, Exa, OpenRouter, and many more. Use when running AI apps, generating images/videos, calling LLMs, web search, or automating Twitter. Triggers: inference.sh, infsh, ai model, run ai, serverless ai, ai api, flux, veo, claude api, image generation, video generation, openrouter, tavily, exa search, twitter api, grok
日本語の概要は準備中です。原文の説明を表示しています。
aiskillstore/marketplace☆ 4322026年10月13日 更新
Stop and consult this skill whenever your response would include specific facts about Anthropic's products. Covers: Claude Code (how to install, Node.js requirements, platform/OS support, MCP server integration, configuration), Claude API (function calling/tool use, batch processing, SDK usage, rate limits, pricing, models, streaming), and Claude.ai (Pro vs Team vs Enterprise plans, feature limits). Trigger this even for coding tasks that use the Anthropic SDK, content creation mentioning Claude capabilities or pricing, or LLM provider comparisons. Any time you would otherwise rely on memory for Anthropic product details, verify here instead — your training data may be outdated or wrong.
日本語の概要は準備中です。原文の説明を表示しています。
syahiidkamil/Software-Engineer-AI-Agent-Atlas☆ 4012026年6月25日 更新
NGS CLI for ChIP/RNA/ATAC-seq. BAM→bigWig with RPGC/CPM/RPKM, sample correlation/PCA, heatmaps/profiles around features, fingerprints. For alignment use STAR/BWA; for peak calling use MACS2.
日本語の概要は準備中です。原文の説明を表示しています。
jaechang-hits/SciAgent-Skills☆ 3782026年9月29日 更新
Provides patterns to build declarative AI Services with LangChain4j for LLM integration, chatbot development, AI agent implementation, and conversational AI in Java. Generates type-safe AI services using interface-based patterns, annotations, memory management, and tools integration. Use when creating AI-powered Java applications with minimal boilerplate, implementing conversational AI with memory, or building AI agents with function calling.
日本語の概要は準備中です。原文の説明を表示しています。
giuseppe-trisciuoglio/developer-kit☆ 3572026年9月10日 更新
Agnes AI API 接入支持与问题排查 Skill。帮助新用户完成 Agnes AI API 的接入配置, 诊断和解决接入过程中遇到的认证、参数、响应、图像生成、视频生成等各类问题。 涵盖 Thinking 模式开启、视频长度调节、流式输出、工具调用等高级功能指导。 兼容 OpenClaw、Claude Code、Hermes、Codex 等工具链。 thinking、stream、tool calling、模型选择、Base URL、响应格式、timeout、超时、轮询、 FAQ、问题排查、调试、免费调用、RPM、video_id、task_id、Prompt 模板、提示词、 生图、生视频、图生图、文生图、图生视频、文生视频、灰度自检、1M 上下文、4K 图片、4K 图、4K、灰度、自检、反馈、Bug、issue、问题反馈、功能建议。
日本語の概要は準備中です。原文の説明を表示しています。
lj1270998580-crypto/Agnes-help-skill☆ 3062026年9月23日 更新
Find the papers that answer a research query in Firecrawl's research paper index — a corpus of paper abstracts whose largest share is biomedical and life-science literature (PubMed, bioRxiv, medRxiv), alongside arXiv preprints in CS, physics, and math — using semantic search, semantic and structural expansion, and in-body verification. Use this skill for literature-finding and paper-retrieval tasks of any kind, including clinical, biomedical, drug, gene, disease, and other life-science questions, whether the answer is a single paper or a full multi-paper set. The index is reached only through the `firecrawl_research_*` MCP tools or the `firecrawl research` CLI subcommands. Calling `firecrawl_search` with its `categories` option set to `["research"]` is a different feature — it filters ordinary web search to research-affiliated websites (the list includes PubMed, bioRxiv, medRxiv, arXiv, and publisher sites) and returns page results from them, without querying the paper records in this index.
日本語の概要は準備中です。原文の説明を表示しています。
firecrawl/firecrawl-claude-plugin☆ 2382026年10月9日 更新
> Generate, modify, and style React components from natural language using the Thesys SDK. Guides schema-driven UI generation, theme customisation, tool calling integration, and deployment to Vite, Next.js, or Cloudflare Workers. Use when the user says "generate UI", "create a component", "build an interface", "Thesys", "generative UI", or asks to turn a description into a React component.
日本語の概要は準備中です。原文の説明を表示しています。
secondsky/claude-skills☆ 2292026年9月28日 更新