2,447 件 ・ 関連度順
概要と使いどころ
Detect contamination and assess genome quality using CheckM, CheckM2, GTDB-Tk, and GUNC for metagenome-assembled genomes and isolate assemblies. Use when checking assemblies for contamination.
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Calculate read depth and coverage across genomic intervals using bedtools genomecov and coverage. Generate bedGraph files, compute per-base depth, and summarize coverage statistics. Use when assessing sequencing depth, creating coverage tracks, or evaluating target capture efficiency.
日本語の概要は準備中です。原文の説明を表示しています。
Quality control and exploration of RNA-seq count matrices before differential expression. Check for outliers, batch effects, and sample relationships. Use when assessing count matrix quality before DE analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt. Use when starting a proteomics analysis with raw or processed MS data. Handles contaminant filtering and missing value assessment.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end CRISPR experiment design from target selection to delivery-ready constructs. Covers guide RNA design, off-target assessment, and specialized editing strategies including knockouts, base editing, and HDR knockins. Use when designing complete CRISPR editing experiments for gene knockout, correction, or tagging.
日本語の概要は準備中です。原文の説明を表示しています。
Assesses ChIP-seq quality across antibody specificity, fragmentation, enrichment, replicate concordance, and library complexity. Computes FRiP, NSC/RSC (phantompeakqualtools), library complexity (NRF/PBC1/PBC2), deepTools plotFingerprint (JS distance, AUC, synthetic JS), ChIPQC, IDR with ENCODE Nself/Nt rules, and detects hyper-ChIPable artifacts. Use when validating an antibody, diagnosing failed peak calls, deciding whether to proceed with downstream analysis, grading against ENCODE thresholds, or auditing replicate concordance.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-compliance thresholds. Use when assessing whether a CLIP library passed, deciding lenient vs stringent peak thresholds, comparing replicates with IDR rescue and self-consistency ratios, or distinguishing failed IP from over-amplified library.
日本語の概要は準備中です。原文の説明を表示しています。
ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. Use when assessing whether an ATAC-seq library passes ENCODE acceptance criteria, diagnosing transposition artefacts, comparing Omni-ATAC vs standard prep quality, or selecting which replicates to drop before peak calling.
日本語の概要は準備中です。原文の説明を表示しています。
Assess genome assembly quality using QUAST for contiguity metrics and BUSCO for completeness. Essential for evaluating assembly success and comparing assemblers. Use when evaluating assembly completeness and quality.
日本語の概要は準備中です。原文の説明を表示しています。
Generate alignment statistics using samtools flagstat, stats, depth, coverage, and mosdepth. Use when assessing alignment quality, calculating coverage, or generating QC reports.
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Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.
日本語の概要は準備中です。原文の説明を表示しています。
Binder design campaign planning, monitoring, and troubleshooting. Use this skill when: (1) Planning a complete binder design campaign, (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.
日本語の概要は準備中です。原文の説明を表示しています。
Safe refactoring workflow using trace-mcp — assess risk, find candidates, check impact, and rename symbols across all files without missing import sites or cross-file references.
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Use when prompting a learner to complete hands-on MATLAB coding exercises, guided practice, debugging drills, code tracing, small MATLAB projects, or MATLAB-script assessment during tutoring. Use when the tutor should create a complete runnable MATLAB script, execute it through MATLAB tools, compare the produced outputs with expected outputs, and evaluate MATLAB programming style.
日本語の概要は準備中です。原文の説明を表示しています。
Interview an instructor and generate a complete MATLAB and Simulink enabled course in IMS Common Cartridge format. Use when the user asks to create a MATLAB course, Simulink course, MATLAB and Simulink curriculum, MATLAB Course Designer-ready course shell, Common Cartridge course package, .imscc export, MATLAB Exercises with validated .m files, or Simulink Exercises with starter and solution model files. Coordinates IDStack, MATLAB Agentic Toolkit, Simulink Agentic Toolkit, matlab-create-course-activity, simulink-create-course-activity, and the existing matlab-generate-grader-assessments skill.
日本語の概要は準備中です。原文の説明を表示しています。
Create MATLAB Course Designer MATLAB Exercise learning activities by wrapping the existing matlab-generate-grader-assessments skill, then validating generated solution.m, template.m, and tests.m files with MATLAB MCP Server tool calls. Use when the user asks to create a MATLAB Exercise, MATLAB course activity, Course Designer MATLAB activity, validated MATLAB solution file, or MATLAB Exercise component folder.
日本語の概要は準備中です。原文の説明を表示しています。
Move quality earlier in the development lifecycle. Covers dev/QA pairing patterns, Three Amigos sessions, TDD facilitation (Red-Green-Refactor), PR review checklists for testability, and Definition of Done with quality gates. Includes shift-left maturity model for team assessment. Use when: "shift left," "TDD," "dev-QA pairing," "definition of done," "testability," "quality culture," "QA in sprint planning." Not for: writing the unit tests themselves — use unit-testing; automated PR test-quality review at scale — use ai-qa-review; multi-quarter QA direction or roadmap — use test-strategy. Related: unit-testing, ai-qa-review, test-strategy.
日本語の概要は準備中です。原文の説明を表示しています。
Fix-and-Flip Analysis — purchase price, ARV, rehab budget breakdown, holding costs, selling costs, profit margin, ROI, timeline, and risk assessment with Flip Score (0-100)
日本語の概要は準備中です。原文の説明を表示しています。
60-Second Property Snapshot — quick assessment without subagents for fast property evaluation with signal, key factors, and CTA for full analysis
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Surface risks through guided questioning, helping users consider pivots, constraints, and prioritization during PRD v0.5 Red Team Review. Triggers on requests to identify risks, stress-test the idea, perform red team review, or when user asks "what could go wrong?", "identify risks", "red team", "risk assessment", "challenge assumptions", "stress test the idea". Consumes all prior IDs (CFD-, BR-, FEA-, PER-, UJ-, SCR-) as interview context. Outputs RISK- entries with owner decisions and mitigations. Feeds v0.5 Technical Stack Selection.
日本語の概要は準備中です。原文の説明を表示しています。
Review and assess every issue in the TMDb project board's Backlog column — re-verify each against current main with a read-only fan-out, close the mechanically dead, promote the actionable to Ready with priority, size and execution order, and leave the rest in Backlog naming the decision they need. Use to groom the backlog, before planning a release, or on a schedule. Runs headless: it decides for itself within the rules below.
日本語の概要は準備中です。原文の説明を表示しています。
Resolve the currently-unresolved review threads on the current branch's PR in one sweep — assess each, fix it (test-first, verified) or reply-only, then reply and resolve — and return a summary. Use standalone to address PR review feedback, or as the thread-handling step invoked by /watch-pr. Repo is adamayoung/TMDb.
日本語の概要は準備中です。原文の説明を表示しています。
Check for data breaches and credential leaks using HaveIBeenPwned API and other sources. Use when: checking if an email or domain is in a known breach, assessing corporate credential exposure, password hygiene audits, or pre-engagement phishing simulation scoping.
日本語の概要は準備中です。原文の説明を表示しています。
Screen job applications against requirements and score candidates objectively. Use when a user asks to review applications, evaluate candidates, screen resumes, rank applicants, assess qualifications against a job description, shortlist candidates, or build a hiring scorecard.
日本語の概要は準備中です。原文の説明を表示しています。