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概要と使いどころ
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems. Use when users need help with ISO 13485 QMS documentation, including (1) conducting gap analysis of existing documentation, (2) creating Quality Manuals, (3) developing required procedures and work instructions, (4) preparing Medical Device Files, (5) understanding ISO 13485 requirements, or (6) identifying missing documentation for medical device certification. Also use when users mention medical device regulations, QMS certification, FDA QMSR, EU MDR, or need help with quality system documentation.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end alternative splicing analysis from FASTQ to differential splicing results for short-read bulk RNA-seq. Aligns with STAR 2-pass cohort-style, performs junction QC (RSeQC, MaxEntScan, SpliceAI), runs rMATS-turbo and leafcutter for concordant differential analysis, optionally MAJIQ V3 for complex events / heterogeneous cohorts, isoform-switching with NMD/ORF/domain consequences (IsoformSwitchAnalyzeR v2 + DRIMSeq+DEXSeq+stageR DTU), and sashimi visualizations. Use when performing comprehensive splicing analysis from raw bulk RNA-seq data; for variant-driven splice prediction see splice-variant-prediction; for rare-disease single-patient outlier detection see outlier-splicing-detection; for full-isoform PacBio/ONT analysis see long-read-splicing.
日本語の概要は準備中です。原文の説明を表示しています。
Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing network topologies. Applicable to social networks, biological networks, transportation systems, citation networks, and any domain involving pairwise relationships.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive drug profiling — mechanism, primary/secondary targets, drug interactions, clinical-trial status, adverse events (FAERS), pharmacogenomics, and approval history. Use for full drug investigation reports, 'tell me about drug X' queries, and assembling drug profiles for clinicians, researchers, or regulatory work.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) profiling for drug candidates. Integrates ADMET-AI predictions, SwissADME drug-likeness, PubChemTox experimental toxicity, ChEMBL clinical data, Lipinski rule-of-five, and CYP interaction data. Use for drug-likeness assessment, BBB penetration, bioavailability, hepatotoxicity prediction, ADME/PK profiling, or screening compound libraries before lab testing.
日本語の概要は準備中です。原文の説明を表示しています。
Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.
日本語の概要は準備中です。原文の説明を表示しています。
Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. Best for proteomics, comprehensive MS data processing. For simple spectral comparison and metabolite ID use matchms.
日本語の概要は準備中です。原文の説明を表示しています。
Expert security auditor specializing in comprehensive security assessments, compliance validation, and risk management. Masters security frameworks, audit methodologies, and compliance standards with focus on identifying vulnerabilities and ensuring regulatory adherence.
日本語の概要は準備中です。原文の説明を表示しています。
Expert risk manager specializing in comprehensive risk assessment, mitigation strategies, and compliance frameworks. Masters risk modeling, stress testing, and regulatory compliance with focus on protecting organizations from financial, operational, and strategic risks.
日本語の概要は準備中です。原文の説明を表示しています。
Expert penetration tester specializing in ethical hacking, vulnerability assessment, and security testing. Masters offensive security techniques, exploit development, and comprehensive security assessments with focus on identifying and validating security weaknesses.
日本語の概要は準備中です。原文の説明を表示しています。
Enhanced architecture guidance for voice-first Brazilian fintech applications. Use when designing voice interfaces, implementing PIX/Boletos, optimizing financial systems, or making technology stack decisions for Brazilian market applications. Integrates with docs/ content, MCP tools for Brazilian market research, enhanced validation scripts, and comprehensive Brazilian compliance patterns.
日本語の概要は準備中です。原文の説明を表示しています。
This skill enables Claude to perform comprehensive accessibility audits. It uses the accessibility-test-scanner plugin to identify WCAG 2.1/2.2 compliance issues, validate ARIA attributes, check keyboard navigation, and assess screen reader compatibility. Use this skill when the user requests an accessibility scan, audit, or compliance check, or when terms like "WCAG", "ARIA", "screen reader", "accessibility testing", or "a11y" are mentioned. It provides actionable insights for improving web application accessibility.
日本語の概要は準備中です。原文の説明を表示しています。
Provide comprehensive techniques for attacking Microsoft Active Directory environments. Covers reconnaissance, credential harvesting, Kerberos attacks, lateral movement, privilege escalation, and domain dominance for red team operations and penetration testing.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive WCAG compliance and accessibility testing covering ARIA, keyboard navigation, screen readers, color contrast, and automated a11y validation.
日本語の概要は準備中です。原文の説明を表示しています。
PHP Standards Recommendations (PSR) overview knowledge base. Provides comprehensive reference for all accepted PSRs including PSR-1,3,4,6,7,11,12,13,14,15,16,17,18,20. Use for PSR selection decisions and compliance audits.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive PR code review for OneKey monorepo. Use when reviewing PRs, code changes, or diffs — covers security (secrets/PII leakage, supply-chain, AuthN/AuthZ), code quality (hooks, race conditions, null safety, concurrent requests), and OneKey-specific patterns (Fabric crashes, MIUI, BigNumber). Triggers on "review PR", "review this PR", "code review", "check this diff", "审查 PR", "代码审查", "review
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive backlink analysis using DataForSEO API. Analyze backlink profiles, find link building opportunities, detect toxic links, compare with competitors, and identify link gaps. Use when user says "backlinks", "link building", "referring domains", "link profile", "toxic links", "link gap", "competitor links", or "domain authority".
日本語の概要は準備中です。原文の説明を表示しています。
Philosophy-first writing partner for Medium with tactical depth. Combines human storytelling values with production-ready technical content tools. Six content modes based on staff pick analysis, mode-specific quality gates, evidence requirements, annotated examples, and comprehensive scripts integration. Designed for sustainable practice, not algorithm gaming.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-compliance thresholds. Use when assessing whether a CLIP library passed, deciding lenient vs stringent peak thresholds, comparing replicates with IDR rescue and self-consistency ratios, or distinguishing failed IP from over-amplified library.
日本語の概要は準備中です。原文の説明を表示しています。
Annotate copy number variant segments with overlapping genes, dosage-sensitivity scores, cancer driver databases, population frequencies, and clinical-variant content. Covers bedtools/pybedtools interval intersection, AnnotSV comprehensive annotation and ranking, ClinGen haploinsufficiency/triplosensitivity scoring, gnomAD-SV/DGV frequency filtering, COSMIC Cancer Gene Census, and ClinVar overlap. Use when interpreting which genes a CNV affects, distinguishing the driver gene of a focal event from passengers, filtering against population CNVs, separating whole-gene from partial-gene overlap, or preparing CNVs for clinical classification.
日本語の概要は準備中です。原文の説明を表示しています。
Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.
日本語の概要は準備中です。原文の説明を表示しています。