「contract」の検索結果

Generates, normalizes, and converts bedGraph signal tracks (4-column chrom/start/end/value, 0-based half-open) with bedtools genomecov, deepTools bamCoverage/bamCompare/bigwigCompare, bedtools unionbedg, and UCSC bedGraphToBigWig. Covers why a raw coverage bedGraph is not comparable across samples until normalized, the CPM/RPKM/BPM/RPGC normalization menu and the conserved-total assumption that makes them wrong under a global perturbation, the strict sorted-non-overlapping-chrom.sizes bedGraphToBigWig contract that silently corrupts a bigWig, effective-genome-size selection, and bin-size aliasing. Use when building or normalizing a coverage/signal track from a BAM, comparing tracks across samples or conditions, converting bedGraph to a browser-ready bigWig, or diagnosing a track that looks plausible but reports wrong heights.

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Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and pybedtools/pyranges/pandas (Python). Covers the 0-based half-open vs 1-based-closed convention boundary and the start-1/end-unchanged conversion, the silent failures (chrom-name mismatch, CRLF, lexicographic-vs-version sort under -sorted), genome/chrom.sizes generation, sorting contracts, BED12 block invariants, validation, makewindows, cross-assembly liftover (liftOver/CrossMap), and BED<->VCF/BAM/FASTA conversion. Use when reading, creating, validating, sorting, lifting between genome builds, or converting interval files, preparing inputs for bedtools/tabix/bigBed, or debugging an off-by-one or empty-overlap result.

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Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

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Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.

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Use this skill when the user asks about towing + recovery operations — separate FMCSA authority class, light-duty vs medium-duty vs heavy-duty wrecker rules, AAA + AAA-Plus contracts, Roadside-Assistance (RA) operations, "non-consensual tow" rules + state-by-state, and how towing operations differ from general freight. Reference state Public Utility Commission + 49 CFR 395 application.

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Use this skill when the user asks about trucking rate negotiation — cost-plus pricing, market rate benchmarking via DAT/Truckstop, fuel surcharge math, how to negotiate with brokers/shippers, when to walk away, contract pricing vs spot rates. Reference DAT Rate Analytics + freight market reports.

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Use this skill when the user asks about carrier-driver relationships — Independent Contractor (IC / 1099) vs Employee (W-2), Owner-Operator lease agreements, the AB5 California law, the DOL 2024 IC test, lease-purchase programs from the carrier side, settlement statements, deductions, and how to structure a compliant IC arrangement. Cite 49 CFR 376 + 1099 IRS rules.

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Pre-commitment attack on a plan by an agent that did not write it. Use when presenting a feature-deep-dive plan, assigning vision-to-fleet briefs, moving a register to build mode, ratifying a scope list, or coding a new contract or table. NOT for built work or DONE reports (use subagent-dispatch).

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Pre-ship safety proof for replacing a live implementation with a canonical one. Use when repointing nodes, tools, or services to a new contract, superseding a schema, retiring a legacy or parallel system, or any 'new way replaces the old way' change. NOT for greenfield or unconsumed additive work.

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Fleet worker contract for wiring assigned files to the v3 right-click menu. Use when handed files from pnpm check:context-menu, or told to 'wire the menu on X', 'do your assigned rows', or 'clear your shard'. NOT for an unassigned one-off menu wiring (use context-menu-v3).

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Analyzes PHP codebase for SOLID principle violations. Detects God classes (SRP), type switches (OCP), broken contracts (LSP), fat interfaces (ISP), and concrete dependencies (DIP). Generates actionable reports with severity levels and remediation recommendations.

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Build production-ready Web3 applications, smart contracts, and decentralized systems. Implements DeFi protocols, NFT platforms, DAOs, and enterprise blockchain integrations.

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A hard-edged writing style contract for timeless, forceful English prose without modern AI tics. Use when users ask for prose or rewrites that must be clean, exact, concrete, and free of AI cadence, filler, or therapeutic tone.

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Design spec with 98 rules for building CLI tools that AI agents can safely use. Covers structured JSON output, error handling, input contracts, safety guardrails, exit codes, and agent self-description.

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Use this skill for internal i18n work in this repository. Covers locale ownership, provider wiring, lazy schema text contracts, and the maintenance surfaces that must stay in sync when package or playground translations change.

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Используйте, когда нужно выгрузить конфигурацию или расширение в исходники через канонический runtime contract проекта.

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Используйте, когда нужно создать информационную базу через канонический runtime contract проекта.

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Используйте, когда нужно загрузить исходники в информационную базу через канонический runtime contract проекта.

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Query Base (Ethereum L2) blockchain data with USD pricing — wallet balances, token info, transaction details, gas analysis, contract inspection, whale detection, and live network stats. Uses Base RPC + CoinGecko. No API key required.

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Tactical negotiation framework based on Chris Voss's "Never Split the Difference." Use when preparing for negotiations, during live negotiation scenarios, analyzing counterpart behavior, crafting responses to difficult conversations, handling objections, salary/contract negotiations, or when asked about negotiation techniques like mirroring, labeling, calibrated questions, or the Ackerman method.

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OrgX operations execution contract for OpenClaw. Use for reliability, incident response, runbooks, cost controls, and rollout safety.

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Pyramid multi-agent orchestration for OpenClaw: routes objectives from a CEO agent down through departments, services and employees via sessions_send / sessions_spawn, collects and merges results, enforces handoff contracts, and writes the final deliverable back to the originating session.

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中国法律法规查询工具。Use when user needs to search Chinese laws, regulations, judicial interpretations. Supports criminal law, civil law, labor law, contract law, intellectual property law. 中国法律、法规查询、法律条文。

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Understand blockchain technology, interact with smart contracts, and evaluate when distributed ledgers solve real problems.

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