1.5万 件 ・ 関連度順
Frontend stack decisions, Cloudflare deployment patterns, component systems, and internal tools architecture. Use for framework selection, deployment strategy, design system bridging, shadcn setup. Activate on "frontend architecture", "tech stack", "Cloudflare Pages", "component library", "internal tools", "shadcn setup". NOT for writing CSS (use frontend-developer), design critique (use design-critic), or backend APIs.
日本語の概要は準備中です。原文の説明を表示しています。
Audit designs, color palettes, and UI components for WCAG 2.1 accessibility compliance, providing specific fixes for contrast, touch targets, focus indicators, and screen reader support. NOT for color harmony aesthetics or design system creation.
日本語の概要は準備中です。原文の説明を表示しています。
Architect scalable styling systems with Tailwind v4, CSS Modules, design tokens, dynamic theming, and container queries. Activate on: design tokens, theming system, Tailwind config, CSS architecture, container queries, dark mode. NOT for: component library creation (use design-system-creator), animation systems (use animation-system-architect).
日本語の概要は準備中です。原文の説明を表示しています。
SOLID design review rules (SRP, OCP, LSP, ISP, DIP) for code reviews: what counts as a real design finding, what is only taste, how to cite it and how severe it is. Use when reviewing a diff, a pull request or recent changes for design problems, when asked for a "SOLID review", "design review", "is this class doing too much", or when a review checklist asks for SOLID. Pair it with the dry skill for duplication and with owasp-asvs for security.
日本語の概要は準備中です。原文の説明を表示しています。
Reviews page hierarchy, grouping, density, actions and state design using consumer-owned product and design-system guidance. Use when asked for a visual design review, page critique or whether a new page communicates its task clearly.
日本語の概要は準備中です。原文の説明を表示しています。
Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
日本語の概要は準備中です。原文の説明を表示しています。
Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the experimental-vs-observational unit distinction and pseudoreplication (Hurlbert 1984; Lazic 2018), randomization mechanics (complete, restricted, stratified, rerandomization, run-order), blocking layouts (randomized complete block, Latin square, incomplete block), factorial designs and interactions, and the split-plot/nested error strata hidden inside multi-batch genomics. Use when deciding the experimental unit and what counts as a replicate, planning randomization and run order, choosing a blocked/factorial/split-plot/nested layout, avoiding pseudoreplication in cell-culture or animal studies, or specifying the random-effects structure of the analysis model. For assigning samples to sequencing batches/lanes/plates and batch-effect correction see experimental-design/batch-design; for regulated clinical-trial randomization see clinical-biostatistics.
日本語の概要は準備中です。原文の説明を表示しています。
Designs novel molecules using REINVENT 4 (de novo, scaffold decoration, linker design, R-group, molecular optimization), MolMIM, Diffusion-based generators (DiGress, DiffSMol), and JT-VAE with explicit handling of multi-parameter optimization (MPO), goal-directed scoring functions, transfer/reinforcement/curriculum learning, synthetic accessibility scoring, and chemical space exploration vs exploitation. Use when designing new chemical matter against a target, decorating a scaffold, linking fragments, or optimizing a hit for multiple ADMET / activity properties simultaneously.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Colic et al. 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving greater sensitivity to small-effect hits than MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).
日本語の概要は準備中です。原文の説明を表示しています。
Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.
日本語の概要は準備中です。原文の説明を表示しています。
Master REST and GraphQL API design principles to build intuitive, scalable, and maintainable APIs that delight developers. Use when designing new APIs, reviewing API specifications, or establishing API design standards.
日本語の概要は準備中です。原文の説明を表示しています。
Generate novel UI from a text prompt via Stitch AI; exports Tailwind/HTML + DESIGN.md for mk:frontend-design handoff. NOT implementing existing designs -- use mk:figma or mk:frontend-design.
日本語の概要は準備中です。原文の説明を表示しています。
Generate a grounded Human Design BodyGraph and whole-chart reading from exact birth data. Use for Human Design charts, BodyGraph, decisions, profile, channels, talents, work, wealth, relationships, mission, or chart-based follow-up questions. Supports Chinese and English.
日本語の概要は準備中です。原文の説明を表示しています。
人类图 (Human Design) 全盘解读技能。根据出生日期、准确时间和出生地点生成 BodyGraph，并以用户语言综合解读类型、策略、权威、人生角色、身体、天赋、财富、关系与使命；支持基于真实盘面的连续问答。触发词: 人类图, Human Design, BodyGraph, 人类图排盘, 人类图解读, 天赋, 使命, 职业, 关系, 类型, 策略, 权威, 人生角色, 通道, 闸门.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill for ANY of the following — do not skip it even if the query seems simple: strategic decisions, business analysis, thesis building, complex problem solving, geopolitical analysis (non-market), philosophical reasoning, academic research, system design, decision under uncertainty, long-form thinking, or any question that benefits from First Principle deconstruction and multi-agent reasoning. ALWAYS use this skill when the user asks about: why something works the way it does, whether a decision is correct, how to think about a complex problem, what could go wrong, analyzing a situation from multiple angles, or any "should I..." question involving real-world trade-offs. This is NOT a market/trading skill — for financial markets, BTC, gold, stocks, forex, macro economics, use money-atlas-intelligence-os instead.
日本語の概要は準備中です。原文の説明を表示しています。
Turn a reference image or mockup into a working local frontend that matches it closely. Inspects the image, extracts the design system (layout, type, spacing, color, components), implements it, then screenshot-compares and iterates to close the gap. Use when the user says "image to code", "build this mockup", "code this screenshot", "make this design real", or provides a UI image to implement. Part of the Product Design set. Uses a browser tool for screenshot verification.
日本語の概要は準備中です。原文の説明を表示しています。
Select the right pharmacologic agent for a child aged 12+ with obesity using the CMAJ 2025 guideline — choosing between GLP-1 receptor agonists, metformin, or orlistat with monitoring guidance. Trigger when a clinician asks which medication to use for pediatric obesity, whether to start semaglutide or metformin in a child, or how to manage obesity pharmacologically in adolescents.
日本語の概要は準備中です。原文の説明を表示しています。
Generate multiple radically different interface designs for a module using parallel sub-agents. Use when user wants to design an API, explore interface options, compare module shapes, or mentions "design it twice".
日本語の概要は準備中です。原文の説明を表示しています。
54 real design systems (Stripe, Linear, Vercel) as HTML/CSS.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive REST API design review with automated linting, breaking-change detection, and design scorecards. Catches inconsistent conventions, missing versioning, and design smells before APIs ship. Use when reviewing a PR that adds or changes API endpoints, auditing an existing API for v2 migration, or establishing API standards for a team.
日本語の概要は準備中です。原文の説明を表示しています。
Practical UI refactoring and visual design review inspired by Refactoring UI by Steve Schoger and Adam Wathan. Use when an AI coding agent needs to improve an existing interface, audit visual polish, redesign a rough UI, review frontend code for hierarchy/spacing/typography/color/depth/image issues, or turn a plain implementation into a cleaner product-quality screen. Do not use for creating UI from scratch, scaffolding a new app, building a new landing page, or designing a new design system unless the user explicitly asks to review or refactor an existing interface.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level transportation engineering covering highway design, traffic flow, intersection design, pavement design, traffic impact studies, and public transit.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level spacecraft design covering mission analysis, subsystem design, power and thermal management, attitude control, communications, and systems engineering.
日本語の概要は準備中です。原文の説明を表示しています。
Expert-level chemical process design covering process flow diagrams, mass and energy balances, equipment sizing, economic evaluation, and sustainable process design.
日本語の概要は準備中です。原文の説明を表示しています。