「spl」の検索結果

Delimits putative species boundaries from molecular data within the de Queiroz 2007 unified-lineage framework using ASAP (Puillandre 2021 successor to ABGD), mPTP C++ (Kapli 2017 successor to bPTP; bPTP is Python NOT R), GMYC single/multi-threshold (Pons 2006; Fujisawa 2013), multilocus BPP v4 with prior calibration from data (NOT defaults; Yang 2015), SNAPP + BFD* for SNP delimitation, DELINEATE (Sukumaran 2021) speciation-process modeling to address Sukumaran & Knowles 2017 PNAS critique that MSC delimits structure not species, integrative-taxonomy congruence (Padial 2010; Carstens 2013), Dsuite for introgression testing before sister claims (Malinsky 2021), and Meyer & Paulay 2005 barcoding-gap-absence caveat. Use when delineating species from DNA barcoding data, resolving cryptic complexes, choosing among ASAP/mPTP/BPP/DELINEATE, calibrating BPP priors, distinguishing introgression from ILS, or applying the Sukumaran-Knowles oversplitting correction.

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Visualize copy number profiles, segments, allele-specific tracks, and cohort patterns from CNVkit, GATK, ASCAT, FACETS, Sequenza, and other callers. Covers genome-wide and per-chromosome log2 scatter plots, B-allele-frequency/minor-allele-fraction tracks, ideograms, cohort heatmaps, circos views, and caller-native plots. Use when creating publication CNV figures, choosing which plot answers a given question, diagnosing a wrong diploid baseline visually, displaying loss of heterozygosity, or deciding what depth-only plots cannot reveal.

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Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.

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Suggests using hydrocortisone 15–25 mg or cortisone acetate 20–35 mg daily in two or three divided oral doses for adult primary adrenal insufficiency (PAI) patients initiating glucocorticoid replacement. The highest dose is given upon awakening, with the second dose either early afternoon (≈2 h after lunch) or split into lunch and afternoon doses; consider total daily dose calculation based on chosen formulation and frequency.

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Decide whether a kidney from a brain-dead deceased donor (DBD) with diabetes mellitus and/or hypertension is suitable for transplantation, using the ISOT 2025 Delphi consensus and Table 4 eligibility checklist. Trigger when a clinician asks "can I use a kidney from a diabetic deceased donor", "is this DBD with HTN/DM acceptable", "ECD donor with diabetes — accept or decline", "DBD eligibility for hypertensive donor", or shares a deceased donor with diabetes or hypertension and needs an accept/borderline/decline decision.

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Calculate the Maryland Aggregate Pathology Index (MAPI) on a deceased donor procurement kidney biopsy to predict graft survival and decide single vs dual vs discard allocation. Trigger when a clinician asks "what's the MAPI score", "interpret donor kidney biopsy", "should I use this marginal kidney", "MAPI cutoff for transplant", "procurement biopsy scoring", or has histology results from a deceased donor kidney and needs an objective grading.

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Modern Angular UI patterns for loading states, error handling, and data display. Use when building UI components, handling async data, or managing component states.

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Expert in building 3D experiences for the web - Three.js, React Three Fiber, Spline, WebGL, and interactive 3D scenes. Covers product configurators, 3D portfolios, immersive websites, and bringing depth to web experiences.

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When the user wants to plan, design, or implement an A/B test or experiment. Also use when the user mentions "A/B test," "split test," "experiment," "test this change," "variant copy," "multivariate test," "hypothesis," "conversion experiment," "statistical significance," or "test this." For tracking implementation, see analytics-tracking.

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Ingeniero de Sistemas de Andru.ia. Diseña, redacta y despliega nuevas habilidades (skills) dentro del repositorio siguiendo el Estándar de Diamante.

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Analyze Amazon product, sales, Amazon Ads, retail-readiness, and Best Seller Rank data to find commercially actionable growth opportunities. Use when Codex needs to identify which ASINs, campaigns, keywords, search terms, product targets, placements, categories, or BSR movements deserve more investment, optimization, harvesting, bid/budget changes, retail-readiness fixes, investigation, protection, or controlled scaling across Sponsored Products, Sponsored Brands, Sponsored Display, search term reports, targeting reports, campaign reports, placement reports, advertised/purchased product reports, Business Reports, organic performance, and BSR history.

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Quick-reference card for all caveman modes, skills, and commands. One-shot display, not a persistent mode. Trigger: /caveman-help, "caveman help", "what caveman commands", "how do I use caveman".

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Run the LangSmith evaluation suite and display pass/fail results

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Fetch and display the full status of the current PR — CI checks, GitHub Actions runs, reviews, and code comments — using GitHub MCP tools. Invoke manually with /pr-status.

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Splits scarce time, budget or traffic across competing products, channels, campaigns or variants by treating them as a multi-armed bandit - Thompson sampling over beta posteriors, with optimism for anything not yet tried enough to judge. Use when deciding what to work on next, how to divide a marketing budget, which product to prioritise, whether to kill something that is underperforming, or when picking a winner among test variants.

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Extract text and tables from PDFs, fill PDF form fields programmatically, and merge multiple PDF files into one. Use when working with PDF documents, form filling, document extraction, splitting, or any PDF manipulation task.

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Generate beautiful, on-brand HTML artifacts — reports, diagrams, diff reviews, slide decks, plans, recaps, dashboards. Loads on creation intents ("create a plan", "make me an implementation plan", "generate a diagram", "build a slide deck", "draft a recap", "visualize this", "render this as HTML", "make me a status update") and exploration intents ("show me three layouts", "explore document shapes", "compare visual treatments", "explore a new design system", "compare replacement brand directions") and iteration intents ("make this beautiful", "polish this report", "make this less generic", "design this", "theme this", "use my brand", "iterate on this design", "review this artifact", "make this bolder", "make this quieter", "simplify this design", "animate this", "improve the look of", "give this a refresh"). Captures brand from the user's codebase, asking, or live site, then applies it to every artifact.

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Manage DAKboard screens, devices, and push custom display data.

日本語の概要は準備中です。原文の説明を表示しています。

Simple time display for Abby.

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Expert-level molecular biology knowledge. Use when working with DNA replication, transcription, translation, gene regulation, cloning, PCR, sequencing, CRISPR, epigenetics, or molecular techniques. Also use when the user mentions 'DNA replication', 'transcription', 'translation', 'gene expression', 'PCR', 'cloning', 'restriction enzyme', 'gel electrophoresis', 'Western blot', 'CRISPR', 'epigenetics', 'promoter', 'enhancer', or 'RNA splicing'.

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Splits large markdown documents into smaller, organized files based on level 2 (default) sections. Use if the user says perform shard document

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Use when the user wants to rename, extract, split, move, or restructure code safely. Examples: "Rename this function", "Extract this into a module", "Refactor this class", "Move this to a separate file"

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Decompose systems into microservices and apply canonical distributed-systems patterns. Use this skill whenever the user wants to split a monolith into services, design service boundaries, choose between microservices and a modular monolith, implement sagas or the outbox pattern, set up CQRS or event sourcing, configure an API gateway or BFF, add resilience (circuit breakers, retries, timeouts), or implement distributed tracing with OpenTelemetry. Also trigger for distributed transactions, service discovery, event-driven architecture, contract testing with Pact, canary releases, and idempotent consumers.

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Systematically find and fix performance problems in applications, frontend and backend, by measuring first. Use this skill whenever the user reports slow endpoints, high latency, poor throughput, memory leaks, large bundles, or slow page loads; wants to profile with cProfile, py-spy, Chrome DevTools, Node --cpu-prof, or perf; run load tests with locust or k6; set performance budgets or SLOs; optimize database queries (EXPLAIN, indexes, N+1); add caching (Redis); improve frontend performance (code splitting, lazy loading, image optimization, memoization, virtualization); or tune the network (CDNs, gzip/br, HTTP/2/3). Also trigger for p50/p95/p99 latency, throughput, error rate, connection pooling, async vs threads, GIL, and memory leak investigations.

日本語の概要は準備中です。原文の説明を表示しています。