「validation」の検索結果

Think and work like an expert Biomaterials Scientist. Use when a task calls for Biomaterials Scientist judgment. Reasons from material-biology interfaces, degradation-product toxicity, and mechanical mismatch to host tissue through ISO 10993 biological evaluation plans, ISO 10993-12 extract conditions, GPC/ICP/SEM characterization, and sterilization validation while treating endotoxin contamination, pH shift from acidic degradation, extract-ratio artifacts, and non-final-form test articles as first-class failure modes.

日本語の概要は準備中です。原文の説明を表示しています。

Think and work like an expert Clinical Laboratory Scientist. Use when a task calls for Clinical Laboratory Scientist judgment. Reasons from pre-analytical–analytical–post-analytical total testing process; EP15/EP09/EP28 validation, Westgard/Sigma IQC, HIL indices (C56), EP23/IQCP, critical-value read-back, type-and-screen/crossmatch, CLSI M100 direct AST, LC-MS/MS C62, and AUTO10 autoverification.

日本語の概要は準備中です。原文の説明を表示しています。

Think and work like an expert Agricultural Engineer. Use when a task calls for Agricultural Engineer judgment. Reasons from mass, energy, and momentum balances on variable biological media through ET-based scheduling, psychrometric grain-drying balances, ASABE D497 draft estimates, EPANET pipe networks, and RTK-GNSS/ISOBUS precision-ag validation while treating soil compaction, clogged drip emitters, grain-bin hotspots, GPS drift, and uncalibrated yield monitors as first-class failure modes.

日本語の概要は準備中です。原文の説明を表示しています。

Think and work like an expert Biogeographer. Use when a task calls for Biogeographer judgment. Reasons from Wallace's ecological vs historical split through GBIF occurrence curation, blockCV spatial cross-validation, MaxEnt/biomod2 SDMs with MESS extrapolation flags, BioGeoBEARS vicariance/dispersal tests, and phylogeographic coalescence while treating random-CV AUC inflation, background bias, and area-cladogram overfitting as first-class failure modes.

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Think and work like an expert Analytical Chemist. Use when a task calls for Analytical Chemist judgment. Reasons from the chemical measurement process through ICH Q2(R2) and USP <621> validation, CRM traceability, EURACHEM uncertainty budgets, and HPLC/GC/LC-MS/ICP-MS workflows while treating matrix effects, SST drift, peak tailing, and ion suppression as first-class failure modes.

日本語の概要は準備中です。原文の説明を表示しています。

Think and work like an expert Animal Nutritionist. Use when a task calls for Animal Nutritionist judgment. Reasons from NASEM/AAFCO requirements, SID amino acids and ideal protein, CNCPS MP/NE balance, and NANP feed libraries through NIR-wet chemistry validation, ileal vs fecal digestibility, pen-structured mixed models, and ARRIVE reporting while treating intake confounds, NIR calibration drift, acidosis/sorting, and pseudoreplicated pens as first-class failure modes.

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Think and work like an expert Atmospheric Scientist. Use when a task calls for Atmospheric Scientist judgment. Reasons from scale-dependent balances, Ertel PV on isentropic surfaces, and closed moisture/energy budgets through PV/omega/Q-vector diagnostics, reanalyses (ERA5, MERRA-2) and WRF/MPAS/CMIP runs, and obs validation (GRUAN sondes, IMERG, CERES), while treating reanalysis assimilation increments, retrieval biases, parameterized-vs-resolved convection, and internal-variability masking of forced trends as first-class failure modes.

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Thesis report synthesis — turn a thesis's markdown artifacts into its letter-size thesis-report.html, then OPTIMIZE it against real page renders. Four-step loop — pack (deterministic Python bundle of all sources + report/metrics.json), author (the LLM writes report/content.html — narrative, KPI tiles, badges, timeline, tables and citations are LLM judgment), assemble (deterministic validation, template injection, Q50 pins, Q47 overflow gate), render + optimize (Chrome headless per-page PNGs — the LLM reads them and iterates until every page is visually clean). Spec 046 Q46–Q50.

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Produce formatted .xlsx financial statement workbooks from XBRL statement data. Uses Bash + openpyxl (Python) following Anthropic FSI xlsx-author conventions for professional Excel output with calculation arc cross-validation.

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Quantitative stock screening, forward-looking valuation outlier detection, backward-looking financial statement validation, PEG ratio analysis, earnings growth profile assessment, turnaround vs value trap discrimination, data mining bias prevention

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Production guidance for international BytePlus Seed Speech text-to-speech. Use for selecting TTS 1.0 versus 2.0, bidirectional or unidirectional streaming, current voices and languages, prompt/prosody controls, subtitle timing validation, billing and concurrency, authorized replicated voices, privacy, error handling, and output QA. Do not use for mainland-China Volcengine Doubao Speech endpoints.

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Select, run, and govern NVIDIA Cosmos world-video generation across Cosmos 3 Generator, Predict2.5, Transfer2.5, downloadable checkpoints, self-hosted NIMs, and hosted preview surfaces. Use for text/image/video-to-world, controlled world transfer, multiview or action-conditioned physical-AI video, local checkpoint pinning, hardware planning, inference approval, and output validation; do not use for Cosmos Reason/Embed-only tasks.

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Produce and review production image-generation and image-editing workflows with Amazon Nova Canvas on Amazon Bedrock, including native InvokeModel payloads, safe authentication, validation, retries, cost controls, provenance, and lifecycle migration checks. Use when a task names Nova Canvas, amazon.nova-canvas-v1:0, Bedrock image generation, Canvas inpainting/outpainting/background removal, image conditioning, color guidance, image variation, virtual try-on, or Canvas fine-tuning.

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Use this skill to turn generated, captured, scanned, or modeled 3D output into production-ready standalone assets for DCC, real-time engine, web, or interchange delivery. It covers requirements, topology repair, scale and axes, UVs, PBR baking, LODs, static and skeletal readiness, rig handoff, optimization, glTF/USD/FBX delivery, validation, QA, and rights/provenance. Do not use it for provider-specific generation prompts, full scene/world building, mocap operation, or exact CAD/manufacturing work.

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Deep behavioral audit of a Lattice skill — proposes 3 review personas relevant to the skill, runs independent scenario analysis from each persona's perspective, then merges only the high-confidence, practical findings into a severity-ordered gap report with proposed fixes. Structural validation (conventions, cross-references) is skill-validate's job — this skill finds gaps that would realistically surface when someone actually uses the skill: missing scenario handling, ambiguous instructions, silent failure cases, and behavioral inconsistencies. Filters out theoretical edge cases, low-likelihood speculation, and findings owned by other skills. Use after writing or significantly changing any skill, or when the user says 'review this skill', 'deep review', 'does this skill work', 'find gaps in this skill', 'stress test this skill', 'review from different angles', or 'skill review'. Standalone — does not call other skills.

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Perform a structured code review by composing validation checklists from relevant atoms based on what code changed. Loads atoms conditionally -- clean-code always, architecture/DDD/security/tests only when the delta touches their domain. Produces a severity-ordered report with specific locations and fixes. Use when the user asks to 'review this', 'code review', 'quality check', 'validate the code', 'check my code', 'review the delta', or 'review this PR'.

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Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.

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Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.

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Reads, validates, and prepares CDISC SDTM and ADaM clinical trial data for analysis. Covers SDTM domain joins (DM, AE, EX, VS, LB, DS), ADaM architecture (ADSL, BDS, OCCDS, ADTTE) with traceability, treatment-emergent AE conventions, baseline derivation, SUPPQUAL/NSV handling, Define-XML 2.1, and Pinnacle 21 / CORE validation. Use when working with clinical trial datasets in CDISC SDTM/ADaM format, preparing analysis-ready data, or validating for regulatory submission.

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BED file format fundamentals, creation, validation, and basic operations. Covers BED3 through BED12 formats, coordinate systems, sorting, and format conversion using bedtools and pybedtools. Use when working with genomic coordinates or preparing interval files for downstream tools.

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Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics. Use when verifying alignment data quality before variant calling or quantification.

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Analyzes base-editing screens for variant function. Covers library design (Sanson 2020 GRACE, Hanna 2021 BRCA1/2 SNV scanning, Cuella-Martin 2021), CBE vs ABE chemistry choice (BE3/BE4 vs ABE7.10/ABE8.20/ABE8e), editing-window math (positions 4-8 from PAM-distal end, wider for ABE8e), bystander-edit quantification and the variant-call ambiguity it creates, sgRNA-efficiency filtering before hit calling, indel byproduct interpretation, the substitution-vs-indel diagnostic, variant annotation against ClinVar / COSMIC, and the Broad be-validation-pipeline. Use when designing a BE variant screen, choosing CBE vs ABE for a specific edit, interpreting bystander-confounded hits, distinguishing functional signal from indel artifact, integrating CRISPResso2 output with screen scoring, or deciding BE vs PE for SNV installation.

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SPR and BLI assay planning, kinetic interpretation, and troubleshooting guidance. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.

日本語の概要は準備中です。原文の説明を表示しています。

Bulk transcriptomics differential expression with count-aware modeling, design validation, contrast handling, thresholded exports, and publication-ready DE figures.

日本語の概要は準備中です。原文の説明を表示しています。