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概要と使いどころ
Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up bioinformatics capabilities or when a bioinformatics task requires specialized skills not yet installed.
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Reads, validates, and prepares CDISC SDTM and ADaM clinical trial data for analysis. Covers SDTM domain joins (DM, AE, EX, VS, LB, DS), ADaM architecture (ADSL, BDS, OCCDS, ADTTE) with traceability, treatment-emergent AE conventions, baseline derivation, SUPPQUAL/NSV handling, Define-XML 2.1, and Pinnacle 21 / CORE validation. Use when working with clinical trial datasets in CDISC SDTM/ADaM format, preparing analysis-ready data, or validating for regulatory submission.
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Performs time-to-event analysis for clinical trials including Cox proportional hazards regression with PH diagnostics, restricted mean survival time (RMST) under non-PH, competing risks via Fine-Gray vs cause-specific Cox, weighted log-rank and MaxCombo for non-proportional hazards, recurrent events (Andersen-Gill, PWP, WLW), and interval-censored data. Use when analyzing time-to-event endpoints (OS, PFS, DOR, TTR, TTNT) in oncology or other clinical trials.
日本語の概要は準備中です。原文の説明を表示しています。
Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.
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Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF-to-FDR calibration (BF >6 ≈ FDR 0.05 from Hart 2017). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.
日本語の概要は準備中です。原文の説明を表示しています。
Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.
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Structured persuasion for tech leads, PMs, and founders—not activity logs. Five scenarios (kickoff, status update, wrap-up, investor pitch, solution selling) on one 5-part framework (Hook→Context→Proposal→Evidence→Ask). AI prompts for missing materials and audience context; pre-submit checklist. Claude Code plugin; Cursor, Codex, and chat via prompts.
日本語の概要は準備中です。原文の説明を表示しています。
Build a single sprint or release test plan. Covers feature decomposition into testable scenarios, requirements-to-test coverage mapping, effort estimation by test type, prioritization matrices (risk × effort), resource allocation, and scheduling with buffers. Use when: "sprint test plan," "release test plan," "what to test this sprint," "test estimation," "coverage mapping." Not for: multi-quarter strategy — use `test-strategy`. Not for: ranking areas by risk — use `risk-based-testing`. Not for: the go/no-go decision itself — use `release-readiness`. Related: test-strategy, risk-based-testing, release-readiness.
日本語の概要は準備中です。原文の説明を表示しています。
Estimates rental income from comparable rentals, builds a full expense model, calculates cash flow and key investment metrics across conservative, moderate, and optimistic scenarios
日本語の概要は準備中です。原文の説明を表示しています。
Draft professional emails for various business scenarios with appropriate tone and structure. Use when a user asks to write an email, compose a message, draft a reply, write a follow-up, create an outreach email, respond to a client, write a cold email, or craft any professional correspondence.
日本語の概要は準備中です。原文の説明を表示しています。
Detox is a gray-box end-to-end testing framework for React Native apps: it runs Jest tests against the app on an iOS simulator or Android emulator and waits for the app to go idle before each step. Use when the user wants to set up Detox, write or fix React Native E2E tests, debug a test that hangs or cannot find an element, or run Detox in CI. Also use when the user mentions "detox," "React Native E2E," "gray-box testing," "detox build," or "Wix Detox." For black-box testing of any mobile app, see appium; for simple YAML UI flows, see maestro.
日本語の概要は準備中です。原文の説明を表示しています。
Cucumber runs behavior-driven (BDD) tests written as plain-language Gherkin feature files and matches each Given/When/Then step to code. Use when the user wants to write feature files, implement step definitions in JavaScript or TypeScript with cucumber-js, share state through a World, add hooks, tags and profiles, or run BDD scenarios in CI. Also use when the user mentions "cucumber," "BDD," "Gherkin," "feature files," "given-when-then," "step definitions," or "behavior-driven." For contract testing, see pact.
日本語の概要は準備中です。原文の説明を表示しています。
Manipulate colors with chroma.js — convert between color spaces (RGB, HSL, LAB, LCH), generate palettes and scales, mix and blend colors, check contrast ratios, and build accessible color systems. Use when tasks involve creating color palettes, theming, accessibility checks, or data visualization color scales.
日本語の概要は準備中です。原文の説明を表示しています。
Writes the App Store "What's New in This Version" text for an app update from the repository's commit history: finds the range since the last shipped version, separates changes users can notice from internal work, drafts plain-text notes within Apple's 4,000-character limit and review guidelines, and returns a trace from every sentence back to its commits. Use when someone asks to "write release notes for the App Store", "generate What's New from git", "summarize changes since the last tag for the store listing", or needs the same notes cut to Google Play's 500 characters.
日本語の概要は準備中です。原文の説明を表示しています。
Optimize mobile app listings for discovery and conversion in Apple App Store and Google Play. Use when tasks involve ASO keyword research, title and subtitle optimization, screenshot and preview video design, A/B testing store listings, review management, localization for international markets, tracking keyword rankings, or improving download conversion rates. Covers both iOS and Android store algorithms and best practices.
日本語の概要は準備中です。原文の説明を表示しています。
Generates and executes load test scripts for APIs using k6, wrk, or autocannon. Creates realistic test scenarios from OpenAPI specs, route files, or endpoint descriptions. Use when someone needs to load test, stress test, benchmark, or find the breaking point of their API. Trigger words: load test, stress test, benchmark, RPS, concurrent users, breaking point, performance test, k6, wrk.
日本語の概要は準備中です。原文の説明を表示しています。
World-class motion graphics expertise combining the animation principles of Disney, the kinetic typography of MK12, and the visual storytelling of studios like Buck and Ordinary Folk. Motion graphics transforms static ideas into dynamic visual experiences. Great motion graphics doesn't just move—it communicates. Every animation should have purpose: to guide attention, reinforce message, create emotion, or clarify concept. The best motion designers understand that restraint is power, that timing is everything, and that the animation should be invisible—viewers should feel the story, not notice the effects. Use when "motion graphics, animation, animate, motion design, kinetic, logo animation, title sequence, lower thirds, animated, after effects, lottie, transitions, motion, motion, graphics, animation, after-effects, lottie, kinetic, typography, design" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
Expert knowledge for real-time and baked lighting in games - from cinematography fundamentals to engine-specific optimization, covering GI, time-of-day, volumetrics, and platform-aware lighting pipelinesUse when "lighting, light design, baked lighting, realtime lighting, lightmap, lightmapping, light probe, reflection probe, global illumination, GI, ambient occlusion, shadow, shadow cascade, time of day, day night cycle, volumetric fog, volumetric lighting, god rays, HDR, tonemapping, bloom, exposure, emissive, area light, Lumen, Enlighten, ray tracing, RTGI, light baking, lighting, global-illumination, lightmapping, shadows, GI, light-probes, reflection-probes, HDR, tonemapping, volumetric, fog, time-of-day, baked, realtime, mixed-lighting, lumen, enlighten, radiosity, ray-tracing, RTGI" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
Expert in entertainment industry concept art workflows, from initial ideation through final production-ready deliverables. Combines traditional art fundamentals with modern digital workflows used at AAA studios and film production houses. Draws from methodologies of industry masters: Feng Zhu's efficient design process, Scott Robertson's perspective and vehicle design systems, Sparth's graphic shape language, and Syd Mead's industrial design thinking. Use when "concept art, visual development, vis dev, keyframe, color script, production design, mood board, thumbnail sketch, environment concept, character concept, prop design, callout sheet, orthographic views, design exploration, photobash, speedpaint, concept-art, visual-development, game-art, film-art, pre-production, ideation, design" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
Expert in building 3D experiences for the web - Three.js, React Three Fiber, Spline, WebGL, and interactive 3D scenes. Covers product configurators, 3D portfolios, immersive websites, and bringing depth to web experiences. Use when "3D website, three.js, WebGL, react three fiber, 3D experience, spline, product configurator, " mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
The new frontier of audio: AI-generated music with Suno and Udio, AI sound effects with ElevenLabs, AI voice cloning, and AI audio enhancement. This skill covers the full spectrum of neural audio synthesis and manipulation. We're in an era where a single person can produce broadcast-quality audio content that would have required studios, musicians, and engineers. AI doesn't replace musical talent—it democratizes production capability. Original compositions in minutes. Custom sound design in seconds. Voice in any language instantly. The practitioners of this skill understand both the creative potential and the ethical considerations. They know when AI audio enhances creativity and when it needs human touch. They're audio directors who orchestrate AI tools like instruments in a symphony. Use when "AI music, generate music, Suno, Udio, AI audio, AI sound, generate soundtrack, background music, sound effects, audio generation, jingle, AI score, stem separation, ai-audio, music, suno, udio, sound-effects, soundtrack, generation, audio-branding, production" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
Generates a behavioral scenario acceptance matrix for comprehensive test coverage planning. Maps user scenarios to acceptance criteria with stable IDs. Use when planning test coverage for a complex feature, before a release or milestone review, or when someone asks what is tested.
日本語の概要は準備中です。原文の説明を表示しています。
AWT — AI-Powered E2E Testing (Beta) workflow skill. Use this skill when the user needs AI-powered E2E web testing — eyes and hands for AI coding tools. Declarative YAML scenarios, Playwright execution, visual matching (OpenCV + OCR), platform auto-detection (Flutter/React/Vue), learning DB. Install: npx skills add ksgisang/awt-skill --skill awt -g and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.
日本語の概要は準備中です。原文の説明を表示しています。
AWT — AI-Powered E2E Testing (Beta) workflow skill. Use this skill when the user needs AI-powered E2E web testing — eyes and hands for AI coding tools. Declarative YAML scenarios, Playwright execution, visual matching (OpenCV + OCR), platform auto-detection (Flutter/React/Vue), learning DB. Install: npx skills add ksgisang/awt-skill --skill awt -g and the operator should preserve the upstream workflow, copied support files, and provenance before merging or handing off.
日本語の概要は準備中です。原文の説明を表示しています。