2,865 件 ・ 関連度順
概要と使いどころ
Think and work like an expert Electric Machines Engineer. Use when a task calls for Electric Machines Engineer judgment. Reasons from magnetic circuit design, dq-frame machine models, FEM flux paths, and drive efficiency maps while treating saturation, cogging, thermal derating, and inverter harmonics as first-class failure modes.
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Think and work like an expert Environmental Engineer. Use when a task calls for Environmental Engineer judgment. Reasons from mass balances, reaction kinetics, source-pathway-receptor transport, and permit limits through BioWin/GPS-X, SWMM, AERMOD/CALPUFF, GAC/IX and activated-sludge design, and 40 CFR Part 136 QA/QC, while treating nitrifier washout, clarifier upset, PFAS breakthrough, and remediation rebound as first-class failure modes.
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Think and work like an expert Environmental Scientist. Use when a task calls for Environmental Scientist judgment. Reasons from source-pathway-receptor linkages, multimedia partitioning, and dose-as-exposure through conceptual site models, fate models (MODFLOW/MT3DMS, AERMOD), SW-846 QA/QC chains, and ProUCL/Mann-Kendall statistics while treating censoring bias, conceptual-model error, well-construction artifacts, and seasonal confounding as first-class failure modes.
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Think and work like an expert Computer Hardware Engineer. Use when a task calls for Computer Hardware Engineer judgment. Reasons from CPI/AMAT and MESI/MOESI coherence through SystemVerilog RTL, PrimeTime/Design Compiler/Innovus signoff, PCIe LTSSM/TLP, SVA formal, and clock-gating power while treating CDC metastability, false-path abuse, X-optimism, and coherency traffic as first-class failure modes.
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Think and work like an expert Computer Graphics Researcher. Use when a task calls for Computer Graphics Researcher judgment. Reasons from the rendering equation, Monte Carlo bias/variance, sampling theory, and BSDF energy conservation through pbrt-v4/Mitsuba 3 references, MIS/ReSTIR/path guiding, DXR 1.2 real-time stacks, 3DGS and NerfBaselines protocols, FLIP/ColorVideoVDP evaluation, OpenUSD/MaterialX/OpenPBR interchange, and ACES 2/OCIO color while treating unconverged references, unequal-time comparisons, denoiser and temporal-reuse bias, scene- vs display-referred color errors, and white-furnace energy failures as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Dermatologist. Use when a task calls for Dermatologist judgment. Clinical-research dermatologist: layered skin anatomy, inflammatory dermatoses and trial endpoints, dermoscopy vs clinical ABCDE, biopsy/pathology, patch testing, telederm, AAD guidelines, and topical steroid potency.
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Think and work like an expert Clinical Microbiologist. Use when a task calls for Clinical Microbiologist judgment. Reasons from blood-culture volume and contamination criteria, staged Gram–ID–AST reporting, MALDI-TOF/VITEK/Phoenix and EUCAST RAST, CLSI M100 vs EUCAST breakpoint discipline, WHONET antibiograms, and NHSN MDRO alerts—treating contaminant vs pathogen and VME/ME as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Climate Risk Analyst. Use when a task calls for Climate Risk Analyst judgment. Reasons from TCFD/IFRS S2 four-pillar disclosure, NGFS Phase V orderly/disorderly/hot-house scenarios, hazard–exposure–vulnerability and RMS/AIR/CLIMADA cat economics, transition carbon-price and stranded-asset pathways, and PCAF financed emissions while treating exposure geocoding quality, Kotz damage-function retraction, and scenario-not-forecast misuse as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Comparative Medicine Researcher. Use when a task calls for Comparative Medicine Researcher judgment. Reasons from species biology, translational validity, and the 3Rs through model-validity frameworks, IACUC protocols, ARRIVE 2.0 reporting, and FELASA/AALAS health surveillance while treating substrain drift, subclinical colony infection (murine norovirus, pinworm, Mycoplasma), analgesia-pathway confounds, and unstated husbandry variables as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Cell Signaling Biologist. Use when a task calls for Cell Signaling Biologist judgment. Reasons from RTK–RAS–MAPK and PI3K–Akt–mTOR phosphorylation networks, pathway crosstalk and feedback; validates with phospho-Western, phospho-flow, and PhosphoSitePlus while treating serum-starvation artifacts, inhibitor off-targets, and RNA footprint vs PTM mismatch as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Bridge Engineer. Use when a task calls for Bridge Engineer judgment. Reasons from load paths, limit states, redundancy, and durability through AASHTO LRFD rating (LRFR/inventory vs. operating), FEM grillage and OpenSees models, HEC-18 scour analysis, and NDE such as half-cell potential and phased-array UT while treating fracture-critical fatigue details, lost composite action, scour, and bearing seizure as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Automotive Engineer. Use when a task calls for Automotive Engineer judgment. Reasons from vehicle-level requirements, regulatory limits, energy/exergy budgets, and distribution-based durability through DFMEA/DVP&R, DoE calibration (INCA, CANape, HIL), Pacejka tire and multibody models, rainflow fatigue, and source-path NVH analysis while treating undocumented build-level and cal-ID deltas, unmet emissions preconditioning and OBD readiness, ADAS sensor misalignment, and cross-domain torque-arbitration conflicts as first-class failure modes.
日本語の概要は準備中です。原文の説明を表示しています。
Think and work like an expert Bacteriologist. Use when a task calls for Bacteriologist judgment. Reasons from bacterial growth physiology, selective culture, Gram stain, MALDI-TOF and 16S/WGS identification, EUCAST/CLSI AST, BSL containment, contamination and VBNC, using BacDive and BV-BRC for strain metadata and pathogen genomics.
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Adversarial verification of research theses — cross-run/cross-thesis contradiction via the entity index, pre-mortem (Klarman/Kahneman: assume the loss already happened, reverse the path), inversion (Munger: invert, always invert), and wrong_if falsifiability review. ≈50-finding cap sorted by severity; content-derived finding IDs; incremental scoping with three backstops; lifecycle hooks at pillar-complete / thesis-complete / pre-reduction.
日本語の概要は準備中です。原文の説明を表示しています。
Vaccine pipeline analysis: immunogenicity and seroconversion studies, lot-consistency trials, healthy-population efficacy designs, and age-cohort bridging, with the ACIP gate built into the value path across the med universe.
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Vaccine catalyst analysis across the two-gate path: CBER BLA review and the ACIP recommendation gate that turns FDA approval into commercial availability. Lot release, procurement milestones, pediatric bridging, and healthy-population efficacy context — dated, verified, and sized per event.
日本語の概要は準備中です。原文の説明を表示しています。
Production guidance for authoring, integrating, and reviewing GSAP animation in browser-rendered media. Use for deterministic kinetic typography, SVG drawing and morphing, motion paths, FLIP transitions, responsive motion systems, or frame-seekable GSAP timelines inside HTML video composition and React-based renderers; not for ordinary CSS transitions or generic frontend development.
日本語の概要は準備中です。原文の説明を表示しています。
Visualize enrichment results using enrichplot package functions. Use when creating publication-quality figures from clusterProfiler results. Covers dotplot, barplot, cnetplot, emapplot, gseaplot2, ridgeplot, and treeplot.
日本語の概要は準備中です。原文の説明を表示しています。
Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications. Use when interpreting clinical significance of variants.
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Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Cell Reports 36:109597), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.
日本語の概要は準備中です。原文の説明を表示しています。
Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.
日本語の概要は準備中です。原文の説明を表示しています。
Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017 tumor tiers. Use when classifying germline variants P / LP / VUS / LB / B, applying VCEP-specific CSpec rules, computing Whiffin BS1, or assigning cancer Tier I-IV per Li 2017.
日本語の概要は準備中です。原文の説明を表示しています。
Workflow for untargeted or targeted metabolomics including preprocessing, normalization, annotation, statistics, and pathway mapping.
日本語の概要は準備中です。原文の説明を表示しています。
Guide human-centered design processes using empathy-driven methodologies. Use when the user says "lets run design thinking" or "I want to apply design thinking"
日本語の概要は準備中です。原文の説明を表示しています。