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概要と使いどころ
Govern how the design system evolves — SemVer for tokens/components, the contribution workflow, deprecation policy, and change communication. Use when the user wants to add/promote/deprecate a component or token, decide a version bump, set up a contribution process, or keep the system from fragmenting.
日本語の概要は準備中です。原文の説明を表示しています。
Create and format WeChat Official Account (公众号) articles with proper Markdown-to-WeChat HTML conversion, rich formatting, cover image guidance, and both API and manual publishing workflows.
日本語の概要は準備中です。原文の説明を表示しています。
Get current time, format dates, calculate date differences, and convert timezones. Use this skill when the user asks about time, dates, timezone conversions, weekdays, or needs date calculations and formatting in any locale.
日本語の概要は準備中です。原文の説明を表示しています。
Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-friendly release notes. Use this skill whenever the user mentions changelogs, release notes, version updates, "what changed", product updates, app store descriptions, or needs to summarize recent development work for non-technical audiences.
日本語の概要は準備中です。原文の説明を表示しています。
Run the CI gate on your machine so it agrees with the runner — deriving the exact command, paths, markers, and env from the workflow file instead of the Makefile, unblocking gate steps that short-circuit and hide the next failure, pinning the linter version CI resolves, building the interpreter/toolchain environment the runner builds, and confirming the run is green instead of explaining a red job away. Use when a check passes locally but fails in CI (or the reverse), when a lint/format job goes red on an untouched file, when setting up a local dev loop for an unfamiliar repo, or before pushing a branch you expect to merge.
日本語の概要は準備中です。原文の説明を表示しています。
Resolve conflicts and merges when several branches are open against one repo at the same time — the hotspot files every change must touch (registry manifests, a single version field, shared tool config, one aggregated test module, tracked build output), union-vs-recompute-vs-rebuild as three different correct resolutions, generated artifacts that must never be merged, non-deterministic serialization that makes every branch conflict, renumbered identifiers that git cannot show you, and why a clean auto-merge is not a passing test. Use when rebasing or merging a long-lived branch, resolving conflict markers, reviewing a merge commit, deciding what a repo should commit vs generate, or setting up a repo that will take parallel contributions.
日本語の概要は準備中です。原文の説明を表示しています。
Manages Python library releases including semantic versioning, changelog maintenance (Keep a Changelog format), release automation with GitHub Actions, and deprecation workflows. Use when planning releases, writing changelogs, automating release pipelines, or communicating breaking changes.
日本語の概要は準備中です。原文の説明を表示しています。
NGS analysis toolkit. Used for BAM to bigWig conversion, quality control (correlation, PCA, fingerprint plots), heatmaps/feature plots (TSS, peaks), suitable for ChIP-seq, RNA-seq, ATAC-seq visualization.
日本語の概要は準備中です。原文の説明を表示しています。
Use Bio.Phylo to read/write phylogenetic trees and perform visualization and statistics; use when tree parsing/conversion, pruning/rerooting, distance calculation, or plotting is required.
日本語の概要は準備中です。原文の説明を表示しています。
Sequence alignment and alignment file processing with Biopython (Bio.Align/Bio.AlignIO), triggered when you need global/local pairwise alignment, MSA read/write/format conversion, or alignment statistics/filtering.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete Mendelian Randomization + single-cell transcriptomics (scRNA-seq) research designs from a user-provided direction. Always use this skill whenever a user wants to design, plan, or build a study combining MR and single-cell data — even if phrased as "help me write a paper on X", "design a bioinformatics study for Y", or "I want to study Z using MR and scRNA". Covers five study patterns (mechanism gene-set, key-cell, candidate-gene reverse validation, exposure-disease-cell triangulation, translational biomarker) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete Mendelian randomization study designs from a user-provided exposure and outcome direction. Always use this skill whenever a user wants to design, plan, or build a Mendelian randomization study — even if phrased as "help me write a paper on X", "design an MR study for Y", or "I want to test whether A causally affects B using GWAS". Covers core two-sample MR design, optional bidirectional follow-up, optional multivariable MR, IV selection logic, ancestry alignment, harmonization, IVW as the default primary estimator, weighted median / MR-Egger / MR-PRESSO / leave-one-out sensitivity analyses, Steiger directionality, heterogeneity / pleiotropy checks, and explicit claim-boundary control. Always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, validation ladder, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete single-compound network-toxicology research designs from one exposure, one disease or toxic phenotype, and a validation direction. Use when a study centers on one compound–one disease link and needs target collection, overlap construction, enrichment, PPI hub prioritization, docking, optional transcriptomic cross-check, and conservative mechanistic synthesis. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete programmed-cell-death (PCD) / regulated-cell-death (RCD) bulk-transcriptome oncology research designs from a user-provided disease and mechanism theme. Always use this skill whenever a user wants to design, plan, or structure a cancer bioinformatics study built around cell-death patterns, tumor microenvironment, prognostic modeling, immune landscape analysis, mutation profiling, and computational drug sensitivity. Covers five study patterns (mechanism-gene-set, subtype-discovery, prognostic-signature, immune-response stratification, translational drug-hypothesis) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete tumor immune-infiltration-guided bulk-transcriptome diagnostic biomarker and machine-learning research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, immune infiltration estimation, immune-linked module discovery, consensus feature selection, diagnostic modeling, nomogram construction, clinical association, and optional prognostic extension or validation. Covers five study patterns (immune-cell-first diagnostic workflow, immune-module-to-biomarker workflow, consensus-ML biomarker workflow, diagnostic-plus-prognostic hybrid workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, reference literature pack, and self-critical risk review.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete comorbidity-oriented shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction. Use when a study links two clinically related diseases through shared DEGs, enrichment, PPI hub genes, machine-learning feature selection, public diagnostic validation, gene-regulatory networks, immune infiltration, and optional downstream follow-up. Covers five study patterns (shared-DEG discovery, hub-gene prioritization, machine-learning biomarker selection, immune/regulatory interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete comparative network-toxicology research designs from a user-provided exposure pair, shared toxic phenotype, and validation direction. Use when a study centers on two related exposures under one outcome and needs target collection, shared-vs-specific target decomposition, enrichment, PPI hub prioritization, docking, optional transcriptomic cross-checks, and conservative mechanistic synthesis. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete conventional non-oncology bioinformatics research designs from a user-provided disease context, process-related gene family or biological theme, and validation direction. Use when a study centers on multi-dataset bulk transcriptome integration, DEG analysis, process-gene intersection, enrichment analysis, GSEA, PPI hub-gene prioritization, TF/miRNA regulatory networks, ROC-based biomarker evaluation, and immune infiltration analysis. Covers five study patterns (process-DEG discovery, enrichment/GSEA interpretation, hub-gene prioritization, regulatory-network and immune interpretation, multi-layer public validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete cross-disease shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction. Always use this skill whenever a user wants to design, plan, or build a multi-dataset study linking two related diseases through shared DEGs, enrichment, PPI hub genes, public validation, regulatory-network analysis, immune infiltration, drug-gene interaction screening, and optional qRT-PCR or cell-line validation. Covers five study patterns (shared-DEG discovery, hub-gene prioritization, regulatory-network interpretation, immune/drug follow-up, bioinformatics-plus-validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete phenotype-scoring bioinformatics research designs for any disease context and any user-defined phenotype, pathway, process, signature, or molecular program. Use when a study centers on gene-set or feature-set definition, intersection with DEGs or candidate features, phenotype scoring, feature selection, diagnostic or stratification assessment, immune or cellular-resolution interpretation, network analysis, and optional orthogonal validation. Covers five study patterns (signature discovery, phenotype scoring, feature selection, immune/cellular interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete dual-disease shared-transcriptome biomarker and hub-gene research designs from a user-provided disease pair and shared-biology direction. Always use this skill whenever a user wants to design, plan, or build a non-oncology two-disease transcriptome study centered on per-disease differential expression, shared-signal intersection or concordance, PPI-based hub-gene prioritization, diagnostic evaluation across both diseases, immune infiltration context, pathway interpretation, and optional orthogonal validation. Covers five study patterns (shared-DEG-first workflow, hub-gene-first shared-biomarker workflow, hybrid shared-biomarker compression workflow, immune-context shared-biomarker workflow, orthogonal validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete reference-grounded single-drug adverse-effect network-pharmacology research designs from a user-provided drug, adverse event, and desired evidence depth. Always use this skill when a user wants to design, plan, or upgrade a conventional network-pharmacology study centered on one fixed drug and one fixed adverse-effect endpoint, using drug-target prediction, adverse-event target collection, overlap analysis, PPI hub prioritization, enrichment interpretation, molecular docking, and optional orthogonal transcriptomic or literature validation. Covers five study patterns (canonical hub-first, cardiotoxicity or electrophysiology-oriented, immune-inflammatory adverse effect, organ-toxicity pathway context, translational validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, dependency/evidence map, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, verified-reference pack, and self-critical risk review.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete reference-grounded single-drug adverse-effect network-pharmacology research designs from a user-provided drug, adverse event, and desired evidence depth. Always use this skill when a user wants to design, plan, or upgrade a conventional network-pharmacology study centered on one fixed drug and one fixed adverse-effect endpoint, using drug-target prediction, adverse-event target collection, overlap analysis, PPI hub prioritization, enrichment interpretation, molecular docking, and optional orthogonal transcriptomic or literature validation. Covers five study patterns (canonical hub-first, cardiotoxicity or electrophysiology-oriented, immune-inflammatory adverse effect, organ-toxicity pathway context, translational validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, dependency/evidence map, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, verified-reference pack, and self-critical risk review.
日本語の概要は準備中です。原文の説明を表示しています。
Generates complete conventional single-gene oncology research designs from a user-provided cancer context, target gene, and validation direction. Use when a study centers on a fixed candidate gene and needs expression, prognosis, clinicopathologic association, functional interpretation, immune context, genomic or epigenetic context, optional drug-response hypotheses, and orthogonal validation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.
日本語の概要は準備中です。原文の説明を表示しています。