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Estimate bivariate genetic correlation (rg) between traits from GWAS summary statistics or individual-level genotypes using cross-trait LDSC, HDL, LAVA, rho-HESS, GREML-bivariate, Popcorn, and HDL-L. Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%. High rg between exposure and outcome motivates CHP-aware MR sensitivity (CAUSE, LHC-MR).

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Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.

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Use this skill when the user asks about workers compensation for trucking — required by state law, classification of drivers, premium calculation (rate × experience modifier × payroll), Common Claim types in trucking, returning injured drivers to work, claims management, premium reduction strategies, and the difference between WC and Occupational Accident insurance for owner-operators. Reference state WC laws + IFTA / fleet insurance.

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Use this skill when a driver is operating under the 150 air-mile short-haul exception and is asked to produce records. Covers the simplified time records required, when ELD is NOT required, and the documentation that satisfies inspectors.

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Use this skill when the user asks about driver ergonomics — back/neck/shoulder injury prevention, seat adjustment + lumbar support, entering and exiting cab safely, load handling techniques, vibration reduction, stretching protocols, and how ergonomics affects workers compensation costs in trucking. Reference OSHA + ATA ergonomics research.

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Execute a bounded Coval evaluation on explicit test cases, then audit conversation, recording and metric evidence. Use when the user requests a run; does not automatically rerun, tune an agent or schedule evaluations.

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Delegate a read-only Coval evaluation, simulation, monitoring, product-how-to, or troubleshooting subtask to Sofia through the official Coval MCP consult_sofia tool. Use when the user needs Coval-specific FDE judgment, analysis of organization data, metric or test-set recommendations, or a diagnosis grounded in Coval runs and conversations.

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Compare before/after Coval runs using matched cases, stable metric versions and inspected conversation evidence. Use to assess a regression or proposed improvement; does not automatically launch or tune anything.

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Troubleshoot Coval OpenTelemetry trace ingestion, missing trace UI, sparse traces, bad simulation or conversation correlation, auth/org errors, oversized payloads, duplicate spans, and production debugging with Trace Search.

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Turn a large dataset (an existing oversized Coval test set, an export of past conversations, or a CSV/JSON of cases) into a small, high-signal Coval test set by removing duplicates, identifying unique scenarios, and selecting a representative, failure-weighted subset — then bulk-loading it with no row cap. Use when the user says "I have thousands of cases", "dedupe my test set", "my test set is too big", "turn this dataset into a test set", "pick representative scenarios", or "my CSV import only kept 10 / uploaded everything".

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Build a compact Coval test set from product requirements, observed conversation failures or a coverage gap. Design realistic scenarios with separate expected behaviors, provenance and controlled voice/persona variation.

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Configure an AI agent to send OpenTelemetry traces to Coval. Use when a user wants to add Coval tracing, instrument an agent for simulations or conversation monitoring, make traces show up in Coval, handle SIP/PSTN/WebSocket trace correlation, or replace the one-command wizard with a security-reviewable manual setup.

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Run the full on-track check on a conversation, project, or keyword the owner names: find the sessions, extract exactly what he typed, dispatch independent judges who go to the live product as him and report what was missed, plan the remedy, and return one page — what he will see, what is missing, the plan. Use when told to check whether work is on track, to audit a project that has drifted, on 'run the on-track check on X', or when a long campaign is about to freeze, hand off, or claim done.

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Locate CCSPlayer_MovementServices::Pawn in CS2 server.dll / libserver.so via IDA Pro MCP and emit a fresh, minimal-unique signature or offset for the local gamedata entry "CCSPlayer_MovementServices::Pawn" (symbol CCSPlayer_MovementServices_Pawn). This is a STRUCT MEMBER OFFSET (schema netvar), not a function. Resolve the CCSPlayer_MovementServices class layout via the schema/network system; the member must satisfy natural alignment. Cross-check with functions that dereference the member. Do not switch output schema: emit the structmember fields below even if the class turns out to be polymorphic - a func_*/vfunc_* payload for this symbol is rejected by canonical_symbol_yaml_bytes. Trigger: CCSPlayer_MovementServices_Pawn, CCSPlayer_MovementServices::Pawn

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Locate CCSBot::Profile in CS2 server.dll / libserver.so via IDA Pro MCP and emit a fresh, minimal-unique signature or offset for the local gamedata entry "CCSBot::Profile" (symbol CCSBot_Profile). This is a STRUCT MEMBER OFFSET (schema netvar), not a function. Resolve the CCSBot class layout via the schema/network system; the member must satisfy natural alignment. Cross-check with functions that dereference the member. Do not switch output schema: emit the structmember fields below even if the class turns out to be polymorphic - a func_*/vfunc_* payload for this symbol is rejected by canonical_symbol_yaml_bytes. Trigger: CCSBot_Profile, CCSBot::Profile

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Locate CBaseEntity::m_iTeamNum in CS2 server.dll / libserver.so via IDA Pro MCP and emit a fresh, minimal-unique signature or offset for the local gamedata entry "CBaseEntity::m_iTeamNum" (symbol CBaseEntity_m_iTeamNum). This is a STRUCT MEMBER OFFSET (schema netvar), not a function. Resolve the CBaseEntity class layout via the schema/network system; the member must satisfy natural alignment. Cross-check with functions that dereference the member. Trigger: CBaseEntity_m_iTeamNum, CBaseEntity::m_iTeamNum

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Write content in David Dias's authentic voice. Use when Quill or any agent needs to create tweets, blog posts, emails, marketing copy, or any content that should sound like David wrote it. David's voice is personal and conversational, mixing professional insight with personal anecdotes. He shares failures openly, values community, and speaks directly to readers with honesty and warmth. Not corporate or overly polished.

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Build a LiveAvatar integration end-to-end — assesses the user's existing stack, recommends the optimal path, and guides implementation. Use when: (1) Building a new LiveAvatar integration, (2) Adding a real-time avatar to an app or site, (3) Connecting LiveAvatar to an existing AI pipeline, (4) User mentions LiveAvatar, real-time avatar, interactive avatar, conversational avatar, or lip-sync avatar, (5) Deciding between Embed, FULL Mode, and LITE Mode, (6) Migrating from HeyGen Interactive Avatar to LiveAvatar.

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Generates Saga pattern components for PHP 8.5. Creates Saga interfaces, steps, orchestrator, state management, and compensation logic with unit tests.

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AI agent and chatbot patterns including personas, pipelines, and messaging integrations. Use when building conversational agents, creating AI personas, designing insight pipelines, or integrating with Slack/Kakao platforms.

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[72] CLOSE. Save and restore session context between conversations. Use when ending a session to preserve progress, or starting a new session to restore context. Triggers on "save session", "end session", "preserve context", "handoff", "continue from last time", or when context window is running low.

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Azure AI VoiceLive SDK for Java. Real-time bidirectional voice conversations with AI assistants using WebSocket.

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OpenViking long-term memory plugin guide. Once installed, the plugin automatically remembers important facts from conversations and recalls relevant context before responding.

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Use this skill when the user requests to generate, create, or produce podcasts from text content. Converts written content into a two-host conversational podcast audio format with natural dialogue.

日本語の概要は準備中です。原文の説明を表示しています。