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概要と使いどころ
Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling, TanStack Router, performance optimization, and TypeScript best practices. Use when creating components, pages, features, fetching data, styling, routing, or working with frontend code.
日本語の概要は準備中です。原文の説明を表示しています。
Create diagrams and visualizations using Mermaid.js v11 syntax. Use when generating flowcharts, sequence diagrams, class diagrams, state diagrams, ER diagrams, Gantt charts, user journeys, timelines, architecture diagrams, or any of 24+ diagram types. Supports JavaScript API integration, CLI rendering to SVG/PNG/PDF, theming, configuration, and accessibility features. Essential for documentation, technical diagrams, project planning, system architecture, and visual communication.
日本語の概要は準備中です。原文の説明を表示しています。
Establish, author, restructure, or audit human-first processor Architecture, Design, Research, Review, and Verification documentation. Use for progressive documentation scaffolding, authority maps, reading paths, document-type content contracts, length-budgeted splitting, or maintainability reviews. Do not use as a substitute for cycle-accurate microarchitecture analysis or RTL implementation.
日本語の概要は準備中です。原文の説明を表示しています。
Record Claude Code sessions with asciinema. TRIGGERS - record session, asciinema record, capture terminal, demo recording.
日本語の概要は準備中です。原文の説明を表示しています。
Enter explore mode - a thinking partner for exploring ideas, investigating problems, and clarifying requirements. Use when the user wants to think through something before or during a change.
日本語の概要は準備中です。原文の説明を表示しています。
Implement tasks from an OpenSpec change. Use when the user wants to start implementing, continue implementation, or work through tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Propose a new change with all artifacts generated in one step. Use when the user wants to quickly describe what they want to build and get a complete proposal with design, specs, and tasks ready for implementation.
日本語の概要は準備中です。原文の説明を表示しています。
Archive a completed change in the experimental workflow. Use when the user wants to finalize and archive a change after implementation is complete.
日本語の概要は準備中です。原文の説明を表示しています。
Professional network graph analyst identifying Gladwellian superconnectors, mavens, and influence brokers using betweenness centrality, structural holes theory, and multi-source network reconstruction. Activate on 'superconnectors', 'network analysis', 'who knows who', 'professional network', 'influence mapping', 'betweenness centrality'. NOT for surveillance, discrimination, stalking, privacy violation, or speculation without data.
日本語の概要は準備中です。原文の説明を表示しています。
Applies Gestalt psychology principles to web layout, spacing, grouping, and visual hierarchy. Proximity, similarity, closure, continuity, figure-ground, common fate, Pragnanz — translated into CSS, component structure, and information architecture. Activate on 'gestalt', 'visual grouping', 'proximity spacing', 'visual hierarchy', 'perceptual organization', 'layout psychology', 'whitespace strategy'. NOT for color theory (use color-theory-palette-harmony-expert), not for accessibility auditing (use design-accessibility-auditor).
日本語の概要は準備中です。原文の説明を表示しています。
Organizing digital life for legacy, emergency access, and death preparedness. Specializes in password management, account documentation, digital asset preservation, and ensuring loved ones can access what they need.
日本語の概要は準備中です。原文の説明を表示しています。
Apply Conway's homomorphism principle to multi-agent system design, recognizing that agent coordination structure predetermines system architecture and capability.
日本語の概要は準備中です。原文の説明を表示しています。
Integration of BDI agent architecture with soft systems methodology for complex organizational problem-solving
日本語の概要は準備中です。原文の説明を表示しています。
Expert in cluttering -- the lesser-known fluency disorder characterized by rapid/irregular speech rate, excessive disfluencies, and frequent ADHD comorbidity. Covers differential diagnosis from stuttering, assessment protocols, therapy approaches (rate control, self-monitoring, pragmatic awareness), technology-assisted intervention, and AI tools for people who clutter. Activate on 'cluttering', 'rapid speech disorder', 'speech rate too fast', 'speech disfluency not stuttering', 'disorganized speech', 'ADHD speech problems', 'cluttering vs stuttering', 'speech intelligibility', 'mazed speech', 'telescoping words'. NOT for stuttering-only treatment (overlap is common but they are distinct), hearing disorders, or voice disorders (pitch, resonance).
日本語の概要は準備中です。原文の説明を表示しています。
Use for insight, reframing, contradiction, impasse, and anomaly-driven problem solving when execution effort no longer helps. NOT for routine optimization, error correction, or well-specified tasks with known solution paths.
日本語の概要は準備中です。原文の説明を表示しています。
AI-powered calendar management and agent-based scheduling coordination. Covers calendar APIs (Google Calendar, CalDAV/iCal), AI scheduling assistants (Reclaim, Clockwise, Motion, Cal.com), building custom calendar agents with MCP, multi-calendar merging, timezone management, focus block protection, meeting fatigue detection, and agent-to-agent meeting negotiation protocols. Activate on: "calendar agent", "AI scheduling", "calendar coordination", "meeting scheduling", "calendar API", "focus time protection", "calendar optimization", "Google Calendar MCP", "Reclaim", "Clockwise", "Motion", "Cal.com", "smart scheduling", "calendar-aware agent", "timezone scheduling", "agent negotiation meetings". NOT for: manual calendar UI component design (use form-validation-architect), project management scheduling or Gantt charts (use project-management-guru-adhd), general time-tracking or pomodoro apps (use adhd-daily-planner for time-awareness), building the agent itself from scratch (use agent-creator).
日本語の概要は準備中です。原文の説明を表示しています。
Cryptographic security for agentic systems — zero-trust agent networking, signed message envelopes (JWS/JWE), capability-based security (ocaps), Merkle tree audit trails, WASM sandboxing, and formal verification. Covers CLI dev tool security, mTLS between agents, permission boundaries (least privilege for AI agents), and supply chain security for skills/plugins. Activate on: "agent security", "zero trust agents", "secure agent communication", "capability-based security", "ocap", "signed messages between agents", "agent audit trail", "sandbox agent execution", "agent permissions", "mTLS agents", "cryptographic verification", "agent supply chain", "OWASP agentic", "prove agent did X", "tamper-proof agent logs". NOT for: application-level SAST scanning (use security-auditor), network firewall rules (use infrastructure), SOC2/HIPAA compliance (organizational), or prompt injection defense (use prompt-engineer).
日本語の概要は準備中です。原文の説明を表示しています。
Defines cell populations in flow and spectral cytometry through manual gates (rectangle, polygon, quadrant, boolean) and reproducible automated gating (openCyto gating templates, flowDensity data-driven thresholds, flowClust model-based gates), organized as a hierarchical GatingSet (flowWorkspace) and round-tripped with FlowJo via CytoML. Covers the canonical gate order (time -> debris -> singlets -> live -> lineage), FMO-vs-isotype boundary setting, gate-order dependence and recompute semantics, rare-event/MRD gating, and per-population statistics. Use when building a gating strategy, automating a manual FlowJo scheme across samples, choosing manual vs data-driven gates, or extracting population frequencies.
日本語の概要は準備中です。原文の説明を表示しています。
Designs and analyzes in vivo CRISPR screens in animal tumor models, organoids, and immune-cell adoptive transfers. Covers bottleneck math (250x cells/sgRNA requires ~25M cells implanted; impossible for most syngeneic models, forcing focused libraries), focused library design (Manguso 2017 Nature 547:413 immune screen; Chen 2015 tumor screens), CRISPR-StAR intrinsic-control screening (Uijttewaal 2025 Nat Biotechnol 43:1848), clonal-dynamics-limited detection, tumor-explant DNA recovery, syngeneic vs xenograft vs PDX considerations, and the relationship to downstream MAGeCK / drugZ analysis. Use when designing in vivo CRISPR screens for tumor / immune / metastasis biology, choosing focused vs genome-wide for animal models, addressing bottleneck-induced clonal collapse, picking the syngeneic / xenograft / PDX model, integrating in vivo with in vitro results, or applying CRISPR-StAR for animal experiments.
日本語の概要は準備中です。原文の説明を表示しています。
Build interactive HTML/web visualizations with plotly (Python/R), bokeh (Python), and gganimate/plotly frames for animation, with awareness of current Kaleido static-export model (post-orca-EOL), HTML file-size bloat, and the limits of interactive-only output for journal submission. Use when producing zoomable/hoverable plots for notebook EDA, supplementary HTML, dashboards, or animated time-course / iteration visualizations.
日本語の概要は準備中です。原文の説明を表示しています。
Generates 3D conformer ensembles using RDKit ETKDGv3 with knowledge-enhanced distance geometry, MMFF94/UFF force-field optimization, CREST + GFN2-xTB semi-empirical refinement, and macrocycle-aware torsion preferences. Provides explicit decision rules for single vs ensemble conformer use, RMSD pruning, energy windows, conformer count, and force-field choice. Use when preparing 3D ligands for docking, generating descriptor input for 3D QSAR, or sampling macrocycle/peptide conformational ensembles.
日本語の概要は準備中です。原文の説明を表示しています。
Normalizes ChIP-seq data using exogenous spike-in (ChIP-Rx with Drosophila chromatin per Orlando 2014 / Egan 2016; E. coli carryover for CUT&RUN/CUT&Tag). Distinguishes RRPM from Rx-Input scaling, integrates with DiffBind / DESeq2 / edgeR / csaw via sizeFactors and DiffBind library-size vectors, applies the Patel et al 2024 *Nat Biotechnol* failure-mode framework, and validates that normalization is applied at the read level (not peak counts). Use when global signal shifts are expected (HDACi, BETi, EZH2i, dosage, target knockdown), when ChIPseqSpikeInFree detects post-hoc shifts, or when validating internal-control regions before publication.
日本語の概要は準備中です。原文の説明を表示しています。
Run remote BLAST searches against NCBI servers using Biopython Bio.Blast.NCBIWWW. Use when identifying unknown sequences, finding homologs, picking the correct BLAST program (blastn/blastp/blastx/tblastn/tblastx/psiblast/megablast/dc-megablast), interpreting Karlin-Altschul E-values, avoiding the max_target_seqs trap (Shah 2019), choosing composition-based statistics, or limiting searches by organism. Covers RID lifecycle, database choice (nt/nr/refseq_select/swissprot), word-size and CBS taxonomy.
日本語の概要は準備中です。原文の説明を表示しています。
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.
日本語の概要は準備中です。原文の説明を表示しています。