「nct」の検索結果

Build production OpenAI Realtime voice agents and low-latency spoken interactions with live audio sessions, WebRTC or WebSocket transport, voice activity detection, tool/function calling, prompt design, logging, consent, privacy, safety, latency, and cost controls. Use for speech-to-speech agents and live voice UX; do not use for separate request-based transcription, text-to-speech, or offline audio generation work.

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Build and evaluate low-latency spoken, multimodal, and translation experiences with Google Gemini Live API and Gemini Enterprise Agent Platform Live API. Use when a media-production or voice-agent workflow needs real-time audio input/output, barge-in, voice configuration, live transcription, live translation, tool/function calling during a spoken session, WebSocket session design, latency QA, quotas/cost review, or Google/Vertex data-governance tradeoffs.

日本語の概要は準備中です。原文の説明を表示しています。

Build production realtime voice agents with Hume's Empathic Voice Interface (EVI): speech-to-speech sessions, empathic/prosodic response design, EVI 3 versus EVI 4-mini selection, WebSocket and SDK integration, tools/function calling, interruption/barge-in, turn-taking, transcripts/audio artifacts, pricing/limits, privacy, safety, consent, and QA.

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Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS. Use when narrowing a GWAS lead SNP to a 95 percent credible set, choosing between in-sample and reference LD, calibrating non-sparse loci with SuSiE-inf or FINEMAP-inf, integrating functional priors via PolyFun, fine-mapping across ancestries with SuSiEx, diagnosing LD mismatch via estimate_s_rss and kriging_rss, handling HLA or long-range LD, or feeding credible sets into coloc.susie for colocalization.

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Visualize enrichment results using enrichplot package functions. Use when creating publication-quality figures from clusterProfiler results. Covers dotplot, barplot, cnetplot, emapplot, gseaplot2, ridgeplot, and treeplot.

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Workflow from differential expression results to functional enrichment analysis. Covers GO, KEGG, Reactome enrichment with clusterProfiler and visualization. Use when taking DE results to pathway enrichment.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies differentially bound ChIP-seq regions between conditions using DiffBind, csaw (sliding windows), DESeq2/edgeR/PyDESeq2 on count matrices, NormR (control-aware), or MAnorm2. Distinguishes three distinct normalization problems (composition bias, trended bias, global shifts) and matches each to its appropriate fix including spike-in scaling. Use when comparing ChIP-seq binding between experimental conditions, choosing normalization for global vs local changes, integrating spike-in data, or reconciling DiffBind/DESeq2 disagreement.

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End-to-end pooled and single-cell CRISPR screen analysis from FASTQ to hit genes. Orchestrates library design QC, guide counting, six-stage screen QC (plasmid Gini, replicate Pearson, CEGv2 PR-AUC, copy-number artifact), method-appropriate hit calling across MAGeCK RRA/MLE, BAGEL2, drugZ, JACKS, and Chronos, cancer-cell-line copy-number correction (CRISPRcleanR / Chronos), batch correction for multi-batch screens, and the specialized branches for combinatorial paralog screens, single-cell Perturb-seq, base-editor variant-function screens, prime-editor screens, and in vivo bottleneck-aware screens. Use when analyzing any pooled CRISPR screen end-to-end, choosing the correct hit-calling method by experimental design, integrating copy-number correction into the pipeline, or branching the workflow for single-cell, combinatorial, base-editor, prime-editor, or in vivo variants.

日本語の概要は準備中です。原文の説明を表示しています。

Visualize differential expression results using DESeq2/edgeR built-in functions. Covers plotMA, plotDispEsts, plotCounts, plotBCV, sample distance heatmaps, and p-value histograms. Use when visualizing differential expression results.

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Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.

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Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Annotate CLIP-seq peaks or crosslink sites to RNA features (5'UTR, CDS, 3'UTR, intron, splice junction, snoRNA, tRNA, ncRNA, repeat elements) with ChIPseeker, RCAS, RBP-Maps (Yeo splicing regulatory maps), and bedtools, applying feature-priority hierarchies, transcript-context resolution, and metagene aggregation. Use when characterizing where in transcripts an RBP binds, comparing peak distribution across regions, generating splicing-regulatory maps relative to alternative-splicing events, or distinguishing exonic vs intronic vs UTR binding.

日本語の概要は準備中です。原文の説明を表示しています。

Shotgun metagenomics workflow with host-depletion-aware QC, taxonomic profiling, functional profiling, AMR follow-up, and reproducible community output tables.

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Access UniProt for protein sequence and annotation retrieval. Use this skill when: (1) Looking up protein sequences by accession, (2) Finding functional annotations, (3) Getting domain boundaries, (4) Finding homologs and variants, (5) Cross-referencing to PDB structures. For structure retrieval, use pdb. For sequence design, use proteinmpnn.

日本語の概要は準備中です。原文の説明を表示しています。

ESM2 protein language model for sequence scoring, embeddings, and plausibility checks. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai1-structure-prediction or boltz-structure-prediction. For QC thresholds, use protein-design-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Generate protein backbones using RFdiffusion, a diffusion-based generative model for de novo protein structure generation. Use this skill when: (1) Designing binder scaffolds for a target protein, (2) Generating novel protein backbones from scratch, (3) Scaffolding functional motifs into new proteins, (4) Specifying hotspot residues for interface design, (5) Creating symmetric oligomers. For sequence design after backbone generation, use proteinmpnn. For structure validation, use alphafold or chai. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

ESM2 protein language model for embeddings and sequence scoring. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai or boltz. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Set up or resume THIS session's retalk user — from your existing users (global ~/.agent-talk or project-local ./.agent-talk) or a new one. Use for first-time setup, to pick which identity this session acts as, or when a command fails with "no identity". agent-talk has no default user; pick one with AskUserQuestion (distinct per parallel session). All human input (relay, passphrase, peers, receive source, delivery mode — auto-receive recommended) is gathered here so send/receive run autonomously afterward.

日本語の概要は準備中です。原文の説明を表示しています。

Use when starting creative work (features, components, functionality, or behavior changes) to clarify user intent, requirements, and design before implementation.

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Use when implementing features or fixing bugs with strict Test-Driven Development (TDD). Activate for coding tasks that require new functionality, refactoring, or comprehensive test coverage, especially when the user mentions TDD or Test Driven Development.

日本語の概要は準備中です。原文の説明を表示しています。

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, or applications. Generates creative, polished code that avoids generic AI aesthetics.

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Generate MATLAB Grader assessment item sets. Use when the user asks to create MATLAB Grader assessment items, generate MATLAB assessment materials, build MATLAB homework assessment items, QTI 3 portable assessment items, or mentions "grader assessment items". Produces complete assessment item folders with description, solution, template, tests, Function call blocks, and optional QTI 3 interchange files.

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Generate MATLAB Grader assessment items that are suitability-gated, profile-driven, feedback-aware, and validated through MATLAB MCP. Produces Script, Function, Class Definition, Class Inheritance, Object Usage, and Class Methods items with MATLAB Grader assessment setup instructions.

日本語の概要は準備中です。原文の説明を表示しています。

Use when tutoring a learner through MATLAB debugging, error interpretation, failed tests, incorrect outputs, array-shape problems, indexing mistakes, function argument issues, or code repair practice. Use for guided debugging sessions, debugging drills, teach-the-agent critique, and evidence-based MATLAB troubleshooting.

日本語の概要は準備中です。原文の説明を表示しています。