「asi」の検索結果

Perform differential expression analysis using edgeR in R/Bioconductor. Use for analyzing RNA-seq count data with the quasi-likelihood F-test framework, creating DGEList objects, normalization, dispersion estimation, and statistical testing. Use when performing DE analysis with edgeR.

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Comprehensive market environment analysis and reporting tool. Analyzes global markets including US, European, Asian markets, forex, commodities, and economic indicators. Provides risk-on/risk-off assessment, sector analysis, and technical indicator interpretation. Triggers on keywords like market analysis, market environment, global markets, trading environment, market conditions, investment climate, market sentiment, forex analysis, stock market analysis, 相場環境, 市場分析, マーケット状況, 投資環境.

Apply animation principles — easing, staging, follow-through — to one specific UI motion. Use when tuning how an animation feels. For product-wide duration and easing tokens use `motion-system` (design-systems); for a full interaction spec use `micro-interaction-spec`.

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Upgrade Three.js games from prototype visuals to premium browser graphics: art-direction critique, procedural model building, material and texture libraries, world prop kits, shaders, VFX, lighting and render pipeline, LOD and instancing, render budgets, and a 10-category visual scorecard. Use when screenshots still look basic or the user asks for premium, AAA, high-fidelity, showcase, or less-basic graphics.

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AV/EDR evasion playbook for Windows. Use when bypassing AMSI, ETW, .NET assembly detection, shellcode execution, process injection, API hooking, and signature-based detection on Windows endpoints.

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Turn a raster logo (PNG/JPG/WebP/screenshot) into a clean minimal SVG with edge smoothness as the primary hard gate and IoU optimized as high as reasonably possible without a fixed global threshold, then into a choreographed logo animation delivered as standalone JS-rendered HTML, applying Disney's 12 animation principles. Use when asked to animate a logo, build a logo reveal / splash screen / brand intro, convert a logo image into animated SVG or HTML, add motion to a vectorized mark, or create loading/idle/hover motion for a brand mark. v2: also handles self-crossing draw-on choreography (split-fill, exact easing subdivision, tip glint), closed variable-width ribbon fitting, and quantitative motion QA (easing probe, ink-delta continuity sweep).

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Analyzes the feasibility of a proposed Meta-analysis topic by searching for existing Meta-analyses and Clinical Trials on PubMed/ClinicalTrials.gov. Use when you need to evaluate if a topic is viable for a new Meta-analysis.

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Assesses whether a medical research topic is worth starting now by separating true novelty from pseudo-novelty, auditing real feasibility under stated resource constraints, and forcing a concrete start / narrow / redesign / stop decision. Always require explicit assumptions and never fabricate references, datasets, resource availability, precedent studies, or publication claims.

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Syzkaller syzlang syntax basics for describing ioctl syscalls

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Basic usage of the General Lake Model (GLM) for lake temperature simulation. Use when you need to run GLM, understand input files, or modify configuration parameters.

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Für Leasing AGB: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt.

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Screenplay format, page craft, the writing process and adaptation (剧本格式/写作流程/改编) — merged from Wendy Henson (spec format rules), Richard Walter (page craft, revision), Neill Hicks (selling vs shooting script, draft chain), Syd Field (master shot, card method, adaptation as original work), Robert McKee (step outline → treatment → screenplay), Julian Hoxter (format elements, adaptation four questions), Diamond & Weissman (one-page nine-step) and Eric Bork — plus an exact typographic grid, element conventions (V.O./O.S., MORE/CONT'D, dual dialogue), a machine-writable output contract (Fountain, with forced markers for Chinese), and Asian industry formats (Chinese 场号制 影视剧本格式, Japanese 柱・ト書き・セリフ / 決定稿). Use when formatting a spec script, choosing the output file format, deciding what goes in action lines, planning drafts and outlines, cutting pages, adapting a novel, play or true story, writing a Chinese TV/film or Japanese-style script page, or preparing a submission-ready draft.

Turn a raster logo (PNG/JPG/WebP/screenshot) into a clean minimal SVG with edge smoothness as the primary hard gate and IoU optimized as high as reasonably possible without a fixed global threshold, then into a choreographed logo animation delivered as standalone JS-rendered HTML, applying Disney's 12 animation principles. Use when asked to animate a logo, build a logo reveal / splash screen / brand intro, convert a logo image into animated SVG or HTML, add motion to a vectorized mark, or create loading/idle/hover motion for a brand mark. v2: also handles self-crossing draw-on choreography (split-fill, exact easing subdivision, tip glint), closed variable-width ribbon fitting, and quantitative motion QA (easing probe, ink-delta continuity sweep).

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Building or editing Simulink (.slx) models that stream signals in frames using DSP System Toolbox — audio, vibration, radar, comms. Use when the prompt names a Simulink block (Discrete FIR Filter, Buffer, Unbuffer, Rate Transition, Downsample, Upsample, Sample-Rate Converter, FIR Decimation, Time Scope, Spectrum Analyzer, From Multimedia File) or an action (frame-based processing, InputProcessing, buffering, overlap, windowing, STFT, short-time Fourier, decimate, downsample, upsample, resample, multirate, anti-aliasing, tunable filter). Prevents silent numerical errors from sample-vs-frame mismatch, wrong block choice, or missing anti-aliasing.

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Calls germline small variants (SNPs and indels) from Oxford Nanopore and PacBio HiFi long reads with Clair3, a two-stage (pileup + full-alignment) deep-learning caller, selecting the chemistry- and basecaller-version-matched model, enabling read-based phasing, and benchmarking against GIAB with stratification. Covers why the model string is the experiment (no auto-detection, silent degradation on mismatch), why ONT homopolymer/STR indels are the residual error whole-genome F1 hides, and the somatic/trio/RNA boundary to the ClairS/Clair3-Trio family. Use when calling germline SNVs/indels from ONT or HiFi BAMs, choosing a Clair3 model, phasing variants, or benchmarking long-read calls.

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Detects A/B chromatin compartments from balanced Hi-C contact matrices via eigenvector decomposition of the distance-normalized, Pearson-correlated cis matrix with cooltools (eigs_cis), then orients (phases) the compartment eigenvector against a GC or gene-density track so the active (A) sign is not arbitrary. Covers the eigenvector-is-a-choice problem (per-arm view_df to remove the centromere gradient; picking the eigenvector by max correlation with activity, not by eigenvalue), GC phasing with bioframe.frac_gc, resolution choice (100kb-1Mb), saddle plots and saddle_strength for compartmentalization strength, the cohesin-loss-strengthens-compartments result, subcompartments (SNIPER/Calder/dcHiC), and cross-condition compartment switching. Use when calling A/B compartments, computing E1/eigenvectors, phasing the eigenvector, building saddle plots, choosing a compartment resolution, quantifying compartment strength, or comparing compartmentalization across conditions.

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Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework. Covers DGEList construction, filterByExpr, TMM/TMMwsp normalization, robust dispersion estimation, glmQLFit/glmQLFTest, TREAT for magnitude-bounded hypotheses, contrasts via no-intercept designs, voom and voomWithQualityWeights for heterogeneous samples, and the edgeR v4 bias-corrected APL changes. Use when running bulk DE with edgeR, choosing edgeR over DESeq2 (small n, transcript DE via catchSalmon, large samples), needing TREAT for a fold-change-threshold hypothesis, troubleshooting v3-to-v4 reproducibility, building paired or interaction designs, or handling library-quality heterogeneity.

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Performs retrosynthetic planning using AiZynthFinder (template-based MCTS), maintained or version-pinned template-free models, ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, configurable MCTS rewards, building-block availability, and forward-prediction checks. Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.

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Apply modern Swift language patterns and idioms for non-concurrency, non-SwiftUI code. Covers if/switch expressions (Swift 5.9+), typed throws (Swift 6+), result builders, property wrappers, opaque and existential types (some vs any), guard patterns, Never type, Regex builders (Swift 5.7+), basic Codable shaping (CodingKeys, custom decoding, nested containers), modern collection APIs (count(where:), contains(where:), replacing()), basic FormatStyle usage, and string interpolation patterns. Use when writing core Swift code involving generics, protocols, enums, closures, or modern language features; route deep Codable to swift-codable, detailed formatting/localization to swift-formatstyle, and API naming to swift-api-design-guidelines.

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Simple scroll-triggered reveal animations using AOS (Animate On Scroll). Use this skill when building marketing pages, landing pages, or content-heavy sites requiring basic fade/slide effects without complex animation orchestration. Triggers on tasks involving scroll animations, scroll-triggered reveals, AOS, simple animations, or basic scroll effects. Alternative to GSAP ScrollTrigger and Locomotive Scroll for simpler use cases. Compare with motion-framer for React-specific animations.

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When the user wants to add recommendations, links, or content to Grokipedia. Also use when the user mentions "Grokipedia," "GEO wiki," "AI encyclopedia," "suggest Grokipedia article," "Grokipedia citation," "Grokipedia listing," "AI search citation," "GEO visibility," or "Grokipedia optimization." For multi-platform parasite SEO strategy, use parasite-seo. For broad AI search visibility, use generative-engine-optimization.

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When the user wants to write, publish, republish, or optimize posts on Medium.com (canonical tags, distribution, Medium SEO). Also use when the user mentions "Medium," "Medium article," "Medium story," "Medium publishing," "canonical Medium," or "publish on Medium." Not for general parasite SEO when Medium is not the target platform—use parasite-seo. For AI search visibility strategy, use generative-engine-optimization.

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Evaluate code (especially LLM-generated) for structural simplicity using Rich Hickey's "Simple Made Easy" framework. Use this skill whenever reviewing a PR, diff, or code snippet for accidental complexity — particularly when the code was generated by an AI coding assistant and line-by-line review isn't feasible. Also use when the user asks about complecting, simplicity vs. easiness, structural coupling, or concept deduplication. Trigger on phrases like "is this simple", "does this complect", "review for complexity", "structural analysis", or any reference to Hickey, Simple Made Easy, or grey-box review.

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Clinical study operations — protocol structure, endpoint selection, eligibility design, sample-size and power planning, site feasibility, and documentation readiness. Use when planning, auditing, or costing a study.

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