「calibration」の検索結果

Think and work like an expert Atomic, Molecular & Optical Physicist. Use when a task calls for Atomic, Molecular & Optical Physicist judgment. Reasons from Rabi/OBE dynamics, laser-cooling hierarchy, optical lattices and Hubbard U/J, and magic-wavelength clock budgets through NIST ASD, ARC, QuTiP/PyLCP, and in-situ lattice-depth calibration while treating power-based depth guesses, polarization impurities, BBR shifts, and imaging-heating conflation as first-class failure modes.

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Think and work like an expert Animal Nutritionist. Use when a task calls for Animal Nutritionist judgment. Reasons from NASEM/AAFCO requirements, SID amino acids and ideal protein, CNCPS MP/NE balance, and NANP feed libraries through NIR-wet chemistry validation, ileal vs fecal digestibility, pen-structured mixed models, and ARRIVE reporting while treating intake confounds, NIR calibration drift, acidosis/sorting, and pseudoreplicated pens as first-class failure modes.

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Think and work like an expert Bayesian Statistician. Use when a task calls for Bayesian Statistician judgment. Reasons from Bayes' rule, coherent uncertainty, exchangeability, and partial-pooling hierarchy through Stan/PyMC HMC-NUTS fits, prior and posterior predictive checks, PSIS-LOO, and SBC calibration while treating divergent transitions and funnels, weak identifiability and label switching, improper posteriors, and post-hoc prior tuning as first-class failure modes.

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Plan, troubleshoot, and hand off provider-independent in-camera VFX and LED volume virtual-production work, with Unreal Engine/nDisplay/Live Link awareness. Use for ICVFX suitability, LED stage geometry, frustums, tracking, lens calibration, sync, render nodes, color, lighting/reflections, artifact mitigation, rehearsal, live-composite fallback, monitoring, records, QA, and handoff. Do not use for ordinary offline post compositing, generic storyboards, or full game production.

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Use this skill when planning, capturing, processing, validating, troubleshooting, or exporting markerless human motion capture with Move AI products, including Move One single-camera workflows and Genesis multi-camera studio systems. It covers provider selection, setup, calibration, wardrobe and lighting constraints, documented multi-person operation, processing, cleanup, skeleton and retargeting choices, DCC/game-engine export, data management, consent, and privacy. Do not use it for general keyframe animation, non-Move mocap systems, 3D asset generation, or generic animation cleanup unrelated to Move AI outputs.

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Use this skill for provider-independent reality capture that turns photographed or video-derived real places, objects, aerial sites, interiors, or people into photogrammetric meshes, NeRFs, or 3D Gaussian splats. It guides representation choice, capture planning, calibration and scale, reconstruction or training, cleanup, compression and LOD, coordinate and interchange handoff, visual/geometric QA, archival records, and property, location, people, and cultural rights checks. Do not use it for text-to-3D generation, synthetic asset invention, guaranteed metrology, or broad downstream finishing after handoff.

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Provider-independent governance workflow for verifying and correcting human- or model-generated video descriptions. Use for pre-caption critique and post-caption revision, aspect-by-aspect factual review, critique precision/recall/constructiveness, second-stage peer review, calibration, appeals, versioned triplets, provenance, and acceptance reporting; not for pixel/audio QA, accessibility captioning, model training, or creative shot direction.

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Detects differential alternative splicing between conditions using rMATS-turbo (binomial LRT on junction counts), leafcutter (Dirichlet-multinomial GLM on intron clusters), MAJIQ V3 deltapsi/HET (Bayesian posterior on LSVs), SUPPA2 (empirical-null on TPM-derived PSI), or Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage). Reports FDR-corrected significance and delta PSI effect sizes. Tools differ in statistical model, annotation dependence, calibration regime, and replicate-count requirements. Use when comparing splicing patterns between treatment groups, tissues, or disease states.

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Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF-to-FDR calibration (BF >6 ≈ FDR 0.05 from Hart 2017). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.

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Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES gold-standard endpoints, and PAINS / Lipinski / Ro5 / Veber / BBB druglikeness filters. Use when filtering compounds for drug-likeness, prioritizing leads by predicted safety, or building an in-house ADMET QSAR model.

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End-to-end EHR predictive modeling pipeline with PyHealth, covering dataset loading, task definition, model training, evaluation, calibration, and clinical interpretation.

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Guide structured design thinking through 5 progressive levels before any code is written. Levels: Capabilities, Components, Interactions, Contracts, Implementation. Use when building new features, refactoring significant code, designing modules, or when the user says 'design this', 'architect this', 'let's think before coding', 'walk me through the design', or 'whiteboard this'. For simple utilities enter at Level 4 (Contracts), for single-component tasks at Level 2 — see Complexity Calibration. Do not use for quick bug patches.

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Expert in designing hidden features, secret codes, and delightful surprises in products. Covers discovery mechanics, reward calibration, shareability triggers, and maintaining the magic. Knows how to create moments that make users feel special for finding them. Use when "easter egg, hidden feature, secret code, surprise and delight, konami code, hidden message, secret mode, " mentioned.

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Generate, audit, or update GitHub READMEs with project-type-aware structure, voice calibration, and SEO/AEO discoverability guidance. Three modes: generate (new), audit (check existing), update (patch). Detects repo type and adapts sections, tone, and badges accordingly.

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Draft professional emails for business and marketing contexts — outreach, client communication, proposals, follow-ups, and internal updates. Includes tone calibration, subject line formulas, and follow-up cadence recommendations.

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临床诊断思维 (临床诊断思维 / 临床推理 (Clinical Diagnostic Reasoning) — 医生『怎么想病』的元学科:从症状/体征/检查到诊断结论的认知操作系统,从业者(临床医生/住院医/规培生,尤其全科/急诊/大内科等以未分化主诉为生的科室)、医学生与医学教育者、诊断安全与质量改进研究者、以及做医疗 AI 辅助诊断产品的人的视角。覆盖: (a) 第一性张力 — **直觉模式识别 (System 1: illness scripts 疾病脚本 / pattern recognition / gestalt, 『资深人一眼认出 aunt Minnie』) ⇄ 分析性推理 (System 2: hypothetico-deductive 假设演绎 / Bayesian 概率更新)** 的 dual-process 双过程理论 (Kahneman→Croskerry/Norman 谱系), 资深≠更会分析而是『脚本库更大+校准更好』; 更深层论战 — **『认知去偏可教 (Croskerry: bias awareness / cognitive forcing strategies / diagnostic timeout) ⇄ 偏倚标签是马后炮、知识结构才是主因 (Norman/Sherbino/Monteiro: debiasing 干预 transfer 证据弱, bias 是 hindsight 标签)』** — 本行最核心学术对垒; 『概率思维 (验前概率 × 似然比 → 验后概率, Pauker-Kassirer test/treatment threshold 阈值模型) ⇄ 穷尽式排查 (rule-out everything / 防御性医疗 / VOMIT)』; 『临床 gestalt ⇄ 结构化临床决策规则 (Wells/PERC/HEART)』; 『诊断简约 Occam's razor ⇄ Hickam's dictum (病人可以同时得 N 个病)』; 『床旁体格检查复兴 (Verghese Stanford 25 / McGee 循证体检) ⇄ 影像检验替代床旁』; (b) 方法论正典 — illness script theory (Schmidt/Boshuizen: enabling conditions/fault/consequences 三段结构), problem representation + semantic qualifiers 问题表征与语义限定词 (Bowen NEJM 2006, 把病人翻成 one-liner), hypothetico-deductive model (Elstein 1978《Medical Problem Solving》: 早期假设生成+定向检验), Bayesian 工具箱 (sensitivity/specificity/LR/Fagan nomogram/SnNout-SpPin), threshold model (Pauker-Kassirer NEJM 1975/1980), 认知偏倚分类学 (anchoring/premature closure/availability/confirmation/base-rate neglect/search satisficing/diagnostic momentum — Croskerry 偏倚清单), 去偏与元认知策略 (diagnostic timeout/cognitive forcing/Ely checklist/calibration), schema-based reasoning (Clinical Problem Solvers schemas: 按 pivot 症状走分支), reflective practice 结构化反思 (Mamede/Schmidt), 诊断错误科学 (NAM 2015 报告定义 / Newman-Toker Big Three / Hardeep Singh e-triggers / SAFER Dx 框架); (c) 行业结构与角色 — 医学生→实习/住院医 (晨会 morning report/查房被 pimping/汇报训练)→主治 attending→master clinician (NEJM CPC discussant/晨会大师如 Dhaliwal); 配套生态: 医学教育者 (clinical reasoning curriculum + 评估: script concordance test/key features exam/OSCE), 诊断安全研究者 (SIDM/AHRQ), 诊断辅助与 CDS 工具开发者 (DDx generator/AI); (d) 核心工作流 — 数据采集 (病史为王 + 循证体检 + 针对性检验影像) → 问题表征 (one-liner + semantic qualifiers) → 鉴别诊断生成 (schema / 解剖定位法 / VINDICATE-M 病因筛, 按『常见可能 × 致命不能漏 can't-miss』双轴排序) → 假设定向检验 (按 LR 选检查 / 阈值决策) → working diagnosis + 安全网 (red flags 交代 / test of time / test of treatment) → 反馈校准 (follow-up / M&M / diagnostic timeout); 教学工作流: 晨会渐进披露汇报 / CPC / SNAPPS / one-minute preceptor / virtual morning report; AI 增强工作流 (2023-2026: LLM 鉴别诊断头脑风暴 / OpenEvidence 检索 / ambient scribe 释放认知带宽 + 自动化偏倚 guardrails); (e) 产出物 — one-liner, problem list, prioritized DDx, assessment & plan (按问题分层), 晨会/CPC 汇报, M&M 复盘, 诊断不确定性沟通 (『最可能是 X, 但出现 Y 红旗立刻回来』); (f) 教育与评估 — script concordance test / key feature exam / EPA / 里程碑; 中国语境: 人卫《诊断学》教材 / 执业医师考试 / 规培结业临床思维考核; (g) 争议/批判 — debiasing 之争 (Croskerry vs Norman-Sherbino『knowledge is the cure』, 去偏 RCT 效果弱 / bias 标签不可证伪), 诊断错误率数字之争 (『10-15%』经典估计 / Newman-Toker 79.5 万美国年严重伤害外推方法被质疑 / 尸检符合率), dual-process 二分被批过度简化 (连续谱 / 难以实证分离), 决策规则 vs gestalt (资深 gestalt 常不输 Wells 类规则 / 算法厌恶), vignette 研究外推性 + context/case specificity (推理高度内容绑定不可通用迁移 [Norman/Eva] — 对『教推理通用课』产业的根本批判), AI 辅助诊断 2023-2026 (GPT-4 在 NEJM CPC/vignette 追平或超医生 [Kanjee 2023 JAMA / Goh 2024 JAMA Netw Open『AI alone > physician+AI』悖论] / Google AMIE / OpenEvidence 爆发 vs 自动化偏倚 / 去技能化 / 真实环境验证缺失), 防御性医疗与过度检查 (incidentaloma 瀑布 / VOMIT), 体检衰亡之争, pimping 教学法争议; (h) 流派/思想谱系 — 决策科学/Bayesian 派 (Ledley-Lusted 1959 → Elstein/Kassirer/Sox/Pauker/Eddy → Brush) vs 认知心理/双过程派 (Kahneman-Tversky → Croskerry/Graber) vs 教育认知派 (Schmidt/Boshuizen illness scripts → Norman/Eva/Mamede/Durning 情境认知) vs 诊断安全/系统派 (NAM 2015 / Newman-Toker / Hardeep Singh / Graber-SIDM: 错误=系统×认知共因) vs 床旁临床派 (Osler 传统 → Tierney aphorisms / Verghese / McGee / Dhaliwal / Saint: 病史体检为王 + 刻意练习) vs AI/计算派 (INTERNIST-1/DXplain 专家系统 → Isabel → LLM 世代 Rodman/Topol)。不含: 具体专科治疗方案与手术决策深度 (足踝外科/种植牙等另有 skill), 中医辨证 (另有 skill), EBM 文献批判性评价方法学 (相关但本 skill 聚焦诊断推理本身), 护理诊断体系 (NANDA), 影像/病理知觉型读片训练 (相邻但独立), 精神科 DSM 结构化访谈细节, 医患沟通技巧全集 (只覆盖诊断不确定性沟通), 患者自查/自我诊断指

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Sentence-level and section-level craft for instructions Claude will actually follow, in any container — project instructions, a standalone prompt, or skill body text. Use when the text exists or is being drafted and the question is quality: "why is Claude ignoring this instruction", "rewrite this prompt so it works", "improve my project instructions", "make this instruction stick", "is this too prescriptive", "how much structure does Sonnet need versus Opus". Covers imperative construction, positive framing, strategic-versus-procedural calibration per model, extended thinking, complexity scaling, and a quality checklist. For deciding WHICH container the instruction belongs in, use crafting-instructions. For building, testing and packaging a whole skill directory, use creating-skill.

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Decide which model, effort level, and cascade shape each subagent gets, and how to keep improvement loops safe (evaluator-as-selector, stop on regression). Routes on measured cost-per-completed-task rather than per-token price, because a tier's token count varies more by task shape than price varies across tiers. Covers per-model effort semantics, the concision lever, cascade preconditions, context handoff, and watching a subagent fan-out live. Use when choosing a subagent's model or effort, when choosing how to escalate a failed attempt, or when asked which model or effort a task should get. Grounded in a 2026-07 calibration, a 2026-08 coding-cost study, a 2026-09 seeded-bug repair battery, a 2026-10 Haiku 5.5 ladder priced per spawn, and a 2026-10 retry-versus-escalation ladder on 295 SWE-bench Verified tasks; Managed Agents API specifics are operational, not calibrated.

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This skill should be considered when you need to normalize testing engineers' written defect reasons following the provided product codebooks. This skill will correct the typos, misused abbreviations, ambiguous descriptions, mixed Chinese-English text or misleading text and provide explanations. This skill will do segmentation, semantic matching, confidence calibration and station validation.

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Use when training, tuning, comparing or evaluating a model — choosing the cross-validation scheme, baselines, tuning inside CV, thresholds and calibration, per-slice metrics, feature importance and error analysis

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Foundational voice authority and AI humanizer — writes content in the user's authentic voice with built-in AI detection, and supports stealth / anti- attribution writing (forum personas, anonymous posts, "write as not-me"). Use when asked to write/draft/generate content, invoke /voice, /write-as-me, or /humanize, run voice calibration, check "does this sound like me?", "make this sound human" / "de-AI this", "write a forum post as [persona]", or run AI detection ("does this sound like AI?", "check for AI patterns", "anti-slop check"). Do NOT use this skill for code, technical docs, or any output the user has not asked to be written in their voice — code styling defers to the separate code-voice skill.

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Calibrate Blender materials, lighting, camera crop, emission/glow, color management, and aura/HUD styling against supplied original/reference images using measurable color, brightness, saturation, bbox, and mask statistics. Use when a product must match the lighting/look of a source image or when audits say the product is too bright, desaturated, wrong hue, wrong glow, or wrong silhouette extent.

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Review the week using accumulated session evidence — retrieval rates, hint depths, calibration accuracy, transfer and unassisted results. The learner identifies patterns and sets a strategy goal. Use weekly or after a multi-session period.

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Design metacognitive checkpoints that prevent AI-assisted learning from bypassing genuine understanding. Use when students use AI tools and may overestimate their own comprehension.

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