245 件 ・ 関連度順
概要と使いどころ
Patient-flow market sizing for med products — prevalence → diagnosed → interested → affordable → covered → treated → persistent, priced as price × duration per cohort, with capacity constraints, named historical analog anchoring, and always bull/base/bear named-driver grids. Use to size a therapy area or product market before any valuation or share work.
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Clinical-trial readout analysis: pull the trial, evaluate the readout with AdCom-style scrutiny (endpoints, statistics, subgroups, missing data, safety, tolerability/persistence), place it in a cross-trial comparison lattice vs SoC and class peers, and size the stock reaction with historical grounding. The judgment core for binary biotech events.
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Think and work like an expert Biogeographer. Use when a task calls for Biogeographer judgment. Reasons from Wallace's ecological vs historical split through GBIF occurrence curation, blockCV spatial cross-validation, MaxEnt/biomod2 SDMs with MESS extrapolation flags, BioGeoBEARS vicariance/dispersal tests, and phylogeographic coalescence while treating random-CV AUC inflation, background bias, and area-cladogram overfitting as first-class failure modes.
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Convert between currencies with real-time exchange rates. Supports 150+ currencies including crypto, with historical rate lookup. Useful for international pricing, financial reporting, and cross-border commerce research.
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Provider-independent workflow for AI agents producing documentary-style montages, archive-driven timelines, interview-supported sequences, nonprofit or advocacy shorts, historical explainers, and hybrid generated/archive edits. Use for editorial thesis development, research/source logs, fact-checking, archive rights, synthetic reenactment disclosure, chronology, interview selects, lower thirds, generated b-roll direction, music restraint, captions, sensitive subjects, review escalation, delivery variants, and documentary QA.
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Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.
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Assesses genetic health of populations for conservation using effective population size estimation (GONE2 for recent Ne trajectory, NeEstimator for contemporary Ne, Stairway Plot 2 and PSMC for historical Ne), F-statistics (hierfstat), runs of homozygosity (detectRUNS), and genetic diversity metrics. Use when estimating effective population size, detecting inbreeding or bottlenecks, or assessing genetic diversity in threatened species from microsatellite or SNP data.
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Internal — for Boundless team members only. Query Boundless broker telemetry tables on Redshift for prod/staging operational data. Use when the user asks about broker health, request evaluations, request completions, proving times, skip rates, telemetry data, or wants to run SQL against the telemetry database on live networks. Also covers historical telemetry through 2026-04-24 stored as Parquet archives in S3 (queried via DuckDB). Do NOT use for debugging local code changes, reviewing PRs, or investigating issues in the codebase itself.
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GitHub 解封 — 账号封禁/限制/恢复的领域操作系统。覆盖：(a) GitHub 官方政策体系 (TOS / 可接受使用政策 / Trust & Safety 执行模式 / 公开申诉路径 / 受制裁地区解读)；(b) 封号原因诊断学 (spam / abuse / 制裁误标 / 2FA 丢失 / ToS 违规 / 账号劫持误判 / ban evasion 等子类型 + 症状→原因映射 + 自我分诊压测)；(c) 申诉实操 craft (写一封能让 T&S 快速判误伤的英文申诉信 + 升级阶梯 + 法务介入边界 + Don'ts)；(d) 制裁与合规硬边界 (OFAC SDN 名单 / 哪些国家或地区真不可达 / VPN 误判路径 / 中国大陆不是美国制裁地区的反复重申)；(e) 中国大陆开发者特别处境 (sanctioned region 误标 + SMS 验证不支持 +86/+852 + Gitee/GitLab/Codeberg/JihuLab 备用迁移 + 私有自托管 Gitea/Forgejo)；(f) 真实案例库 (~30+ 公开案例分类拆解：误伤 / 真违规 / 制裁误标三类各自赔率与申诉成功路径)。伦理锚绝不软化：不教 ban evasion / 不教撒谎式申诉 / 真违规承认改进 / 丢 2FA 无恢复因子则诚实告知 / 中国制裁误标靠申诉不靠换 VPN / 申诉 6 个月窗口必算清 / 约 3% (业内估) 真违规恢复 vs 约 79% (业内估) 误伤申诉成功率分层标。 (GitHub Account Reinstatement — the domain operating system for GitHub (and analogous platform) account suspension, restriction, appeal, and recovery. Covers: (a) GitHub official policy architecture (TOS / Acceptable Use Policies / Trust & Safety enforcement patterns / public appeals pathways / sanctioned-region interpretation); (b) suspension-cause diagnostics (spam / abuse / sanctions mis-flag / 2FA loss / ToS violation / account hijack false-positive / ban evasion taxonomy + symptom→cause mapping + self-triage pressure test); (c) appeal craft (writing an English appeal letter that gets T&S to fast-track a false-positive ruling + escalation ladder + legal-engagement boundary + Don'ts); (d) sanctions and compliance hard boundaries (OFAC SDN list / which countries/regions are truly unreachable / VPN false-positive paths / China is NOT a US-sanctioned region — repeated emphasis); (e) mainland China developer special circumstances (sanctioned-region mis-flag + SMS verification does not support +86/+852 + Gitee/GitLab/Codeberg/JihuLab fallback migration + self-hosted Gitea/Forgejo); (f) real-case library (~30+ public cases with categorized analysis: false-positive / genuine violation / sanctions mis-flag, each with win-rate and appeal success path). Ethical anchors absolutely not softened: do NOT teach ban evasion (creating new accounts turns a temp ban into a permanent one — the single biggest mistake); do NOT teach social engineering or lying in appeals (misuse + actually confirms violation); genuine violations: admit + improve beats denial; lost 2FA + no recovery factor → do not pretend recovery is possible; China sanctioned-region mis-flag → fix via appeal, not repeated VPN switching; appeal form 6-month window must be counted carefully; historical 约 3% (业内估) genuine-violation recovery vs 约 79% (业内估) false-positive appeal success rate stratification must be honestly labeled. Anti-samples (explicitly describe harm, never endorse): developer permabanned for ban evasion / open-source team org-banned for personal attacks in public issues / cases where repeated VPN switching escalated risk-control severity.) Master OS — automated mastery of GitHub Account Reinstatement — the domain operating system for GitHub (and analogous platform) account suspension, restriction, appeal, and recovery. Covers: (a) GitHub official policy architecture (TOS / Acceptable Use Policies / Trust & Safety enforcement patterns / public appeals pathways / sanctioned-region interpretation); (b) suspension-cause diagnostics (spam / abuse / sanctions mis-flag / 2FA loss / ToS violation / account hijack false-positive / ban evasion taxonomy + symptom→cause mapping + self-triage pressure test); (c) appeal craft (writing an English appeal letter that gets T&S to fast-track a false-positive ruling + escalation ladder + legal-engagement boundary + Don'ts); (d) sanctions and compliance hard boundaries (OFAC SDN list / which countries/regions are truly unreachable / VPN false-positive paths / China is NOT a US-sanctioned region — repeated emphasis); (e) mainland China developer special circumstances (sanctioned-region mis-flag + SMS verification does not support +86/+852 + Gitee/GitLab/Codeberg/JihuLab fallback migration + self-hosted Gitea/Forgejo); (f) real-case library (~30+ public cases with categorized analysis: fa
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Computes a numeric or categorical answer to a quantitative data-science question by cleaning and analyzing local data files (CSV, Excel, TSV, and scientific formats .npz/.fits/.h5) with pandas, numpy, and scipy. Use whenever a task ships its own dataset (in whatever local directory it provides) and asks you to derive a value via statistical, geospatial, temporal, ratio, percentage, growth-rate, correlation, signal-processing, orbital, or forecasting analysis. Spans domains including archeology (demographics, paleoclimate proxies, radiocarbon dating, historical conflicts); biomedical/bioinformatics (tumor histology, genes, proteins, peptides, genomic variants); environmental (water quality, bacterial/Enterococcus exceedance, rainfall correlations, environmental justice); legal/consumer (fraud, identity theft, consumer complaints by state/metro); wildfire (incidents, causes, suppression costs, acres burned, fatalities, geospatial intersections); and astronomy/heliophysics/space weather (satellite telemetry TLE/Swarm/SP3, indices OMNI/GOES, solar activity, atmospheric density, orbital mechanics, forecasting).
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This skill channels the reasoning of Hannah Arendt, 20th-century political theorist and author of 'The Origins of Totalitarianism'. Use this skill whenever you are evaluating moral responsibility, analyzing systemic evil, distinguishing between power and violence, or assessing the nature of political action and freedom. Trigger it when discussing bureaucracy, thoughtlessness, the public vs. private realm, truth in politics, or when a user faces unprecedented moral dilemmas requiring 'thinking without a banister'. Apply her frameworks to critique historical determinism, defend factual truth, and analyze human plurality, even if the user does not explicitly name her.
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Skill to query and update a mistake notebook to memorize mistake. Use this skill when: 1. Encountered a severe problem, needs to recall for historical problem solving experience 2. After fixed a severe mistake with a clear solution valuable to be recorded 3. User requested 'Do not make this mistake again'
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Read live Hyperliquid market data from the desk computer with curl or the Python SDK - mid, mark and oracle prices, order book depth, funding (current, predicted, historical), open interest, volume, candles, perp and spot metadata, margin tiers, and how to save datasets for the strategy lab. Read-only, no key. Use for any market brief, depth read, funding question or data pull.
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Read a Hyperliquid account from the desk computer - positions and margin, spot balances, open orders including trigger details, fills, funding paid, ledger updates, order status by oid or cloid, historical orders, portfolio history, fee tier and rate-limit budget - with curl and Python SDK examples. Read-only, needs only the account address. Use for sizing inputs, book checks, reconciliation and reviews.
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Estimates task effort by analyzing complexity, dependencies, historical velocity, and risk factors. Produces a structured estimate with confidence levels.
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Design structured perspective-taking activities with anti-projection guardrails. Develops genuine understanding of complexity across history, social sciences, and literature — not performed empathy.
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Design a complete document-based history lesson using the Reading Like a Historian four-part structure. Use when planning a primary source inquiry lesson or converting a textbook lesson into document-based investigation.
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Create a writing scaffold teaching the genre conventions specific to an academic discipline. Use when students write lab reports, historical essays, or other discipline-specific text types.
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Retrieve the current public details of one Shopee listing from a supported product URL, including price, discount, sales, stock, variants, media, brand, category, shop, and rating data. Use when a user provides a Shopee product URL and asks for listing details, SKU variants, inventory, pricing, or competitor-page analysis. Do not use for keyword search, historical trends, reviews, or seller-account operations.
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Query Walmart product details via Nexscope, including pricing history and sales trends. Trigger when users mention Walmart product detail, Walmart product data, Nexscope, Walmart price trends, Walmart sales trends, Walmart product detail, Walmart price history, Walmart sales trend, Nexscope product. Even if the user does not explicitly mention "Nexscope", trigger this skill whenever their need involves viewing detailed information, historical price changes, or sales trends for a single Walmart product.
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Advanced Amazon product search and filtering powered by Nexscope data, supporting multi-dimensional criteria including category, price, monthly sales, keywords, BSR rank, review count, rating, package dimensions, weight, fulfillment type, and more. Trigger when users mention Nexscope product selection, Amazon product search, advanced product selection, BSR filtering, sales rank filtering, keyword-based product discovery, category search, competitor screening, niche product discovery, historical rank filtering, or similar terms. Even if the user does not explicitly mention "Nexscope," trigger this skill whenever the request involves multi-criteria Amazon product search, sales-metric-based filtering, or advanced product selection beyond simple keyword search.
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Amazon reverse product selection: filter Amazon niches and keywords by 30+ business dimensions (market size & growth, price tiers & share, competition density & top concentration, demographics such as age/gender/income, review highlights & pain points) from a metrics pool aggregated from historical business insight reports. Trigger when users mention reverse product selection, metrics filtering, niche reverse lookup, blue ocean niche discovery, low-competition niche, newcomer-friendly niche, brand-fragmented market, pain-point entry, feature reverse lookup, pricing tier opportunity, demographic-based selection, or similar terms. Even if the user does not explicitly say "reverse product selection," trigger this skill whenever the request involves filtering Amazon niches that match specific business criteria.
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Query traffic keyword lists for an Amazon ASIN via Nexscope, including traffic source type, conversion type, organic rank, and ad rank with historical month and multi-dimensional sorting. Trigger when user mentions ASIN reverse traffic keywords, traffic keyword list, keyword traffic structure, organic/ad keyword analysis, keyword conversion type, Nexscope traffic keyword, Amazon traffic keywords, reverse ASIN keywords — even if "Nexscope" is not explicitly mentioned, as long as the need involves viewing keyword traffic sources and keyword lists for a specific ASIN.
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Perform a read-only, evidence-first intake of an existing mini-program repository before planning or modifying code. Use when users ask to take over, understand, audit, resume, scope, or continue a WeChat or other mini-program project; when project facts may conflict with historical documents; or when an agent needs the framework, rules, Git state, build path, risks, unknowns, protected behavior, and change boundary. Produces a project fact map and handoff without changing code, installing dependencies, building artifacts, or claiming runtime, device, cloud, upload, acceptance, or release status.
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