「matrix」の検索結果

Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.

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Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.

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Analyzes pooled CRISPR screens with MAGeCK (Li et al 2014), covering count generation (mageck count), the RRA two-condition workflow (mageck test using alpha-RRA over per-sgRNA negative-binomial p-values), the MLE multi-condition workflow (mageck mle with explicit design matrix and beta-score output), normalization choice (median vs total vs control-sgRNA vs spike-in), sgRNA efficiency injection, paired-sample testing, time-course design, drug-screen versus dropout-screen design matrices, MAGeCKFlute and MAGeCK-VISPR downstream visualization, and decision logic for when to use MAGeCK vs JACKS / BAGEL2 / drugZ / Chronos. Use when running a fresh CRISPR screen analysis, picking RRA vs MLE for the experimental design, choosing a normalization method from QC signatures, debugging MLE convergence failure or NaN beta scores, comparing MAGeCK output across tools, or building a batch-aware multi-cell-line / multi-condition MLE design matrix.

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Complete guide for upgrading xUnit 2.9.x to 3.x. Use when upgrading xUnit v2 to v3 or understanding xUnit v3 new features and breaking changes. Covers package updates, async void fixes, IAsyncLifetime adjustments. Includes new features: Assert.Skip, Explicit Tests, Matrix Theory, Assembly Fixtures. Keywords: xunit upgrade, xunit v3, xunit 3.x, xunit migration, xunit upgrade, xunit.v3, OutputType Exe, IAsyncLifetime v3, Assert.Skip, SkipUnless, SkipWhen, Explicit attribute, MatrixTheoryData, AssemblyFixture, breaking changes

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Build a structured SOC escalation matrix defining severity tiers, response SLAs, escalation paths, and notification procedures for security incidents.

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External SSL VPN / remote-access appliance attack matrix — Cisco ASA/AnyConnect, Fortinet FortiGate/FortiOS, Citrix NetScaler/ADC, Palo Alto GlobalProtect, Pulse Secure / Ivanti Connect Secure, SonicWall, F5 Big-IP. Covers version fingerprinting, CVE matrix (2018-2026), AAA backend identification, default credentials, configuration-disclosure paths, pre-auth RCE/SSRF/path-traversal exploits where applicable. Built from authorized-engagement Cisco ASA testing plus 2024-2026 enterprise VPN CVE landscape. Use whenever the target's perimeter exposes any SSL VPN appliance or remote-access gateway — these are the most common initial-access points in 2024-2026 actor TTPs.

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Classify every destructive/gated action an agent body can attempt (git, filesystem, network, shell, github) into block/approve/allow tiers, and audit whether the pre-tool and post-tool governance backing that classification is real: blocked actions proven zero-side-effect by a negative fixture, every denial backed by a receipt and a transcript event, every block-tier denial paired with a safe alternative, and no unmanaged or same-UID body ever marked "contained." Use when building or reviewing Agent Harbor's C5 governance gate (destructive git blocker, approval request/result, denial receipts), gating a new tool surface before it can run destructive commands, or auditing whether an existing "destructive-action blocked" claim actually has evidence behind it. NOT for proving an existing sandbox boundary actually contains an adversary once an action is isolated (use sandboxed-adversarial-test-harness), deciding where in a DAG to place a human review node or designing the approval UX itself (use human-gate-designer), or designing the general work-receipt schema across an entire agent task (use agent-work-receipt-designer).

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OpenClawのCIで処理待ちや実行環境の不足を調べ、ランナー登録数・並列実行数・ジョブの分割や配置を、計測結果に基づいて調整するスキル。

• OpenClawのCI待ちを調べたいとき
• 集中時のランナー登録数を見積もる
• 並列実行数やテスト分割を見直す

作業の依存関係を整理し、独立した調査・実装・検証を並行して進めるためのスキルです。変更先の競合を避け、各作業の完了状況と確認結果を表にまとめます。

• 独立したファイル調査の一括実行
• 複数エージェントでの分担実装
• Git worktreeで変更先を分けたいとき

採点済みの競合情報を、市場マップや比較表、差別化の余地、優先施策を含むレポートにまとめます。経営層への報告や、チームで競争方針を決める場面に役立ちます。

• 経営層や取締役会向けの競合報告
• 完成済み競合プロフィールの統合
• 差別化の余地と競合脅威の検討

競合のブランド表現やサービス、実績などを共通の基準で採点し、根拠付きの比較カードと戦略上の二軸図にまとめ、自社が狙う位置の競合を把握するスキル。

• 共通基準で競合を比較したいとき
• 根拠付きの競合カード作成
• 二つの戦略目標で競合を整理したいとき

Turn messy user research notes, interviews, support tickets, surveys, and product context into an evidence-backed decision room: a single HTML artifact with an evidence ledger, theme map, confidence heatmap, opportunity matrix, decision memo, and experiment queue. Use when teams need to move from qualitative signals to product or design decisions without fabricating certainty.

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Keep a Markdown table readable in a narrow terminal of about 100 display columns - a wide table or one carrying prose in its cells wraps into unreadable ragged rows. Always call read_skill for bundled:table-fit before emitting a Markdown table in a final answer, and load it as soon as the answer starts forming as a comparison, a mapping, a feature matrix, a pros-and-cons, an options rundown, or a per-item summary across several dimensions. Do not load it for a table already inside a file being edited, for code, data, or test fixtures that merely look tabular, for tables the user pasted for you to read, or for an answer with no table and no tabular shape forming.

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Create branded architecture, architecture delta, IT current-state, flowchart, sequence, state machine, ER/data model, timeline, swimlane, quadrant, radar/spider, polar chart (polar/radial lollipop), loop/flywheel, nested, tree, org chart, layer stack, exploded axonometric, axonometric plan, Venn, pyramid/funnel, treemap and marimekko, heatmap, bar and dumbbell, waterfall, line (slopegraph, ridgeline, streamgraph, bump), Gantt and scatter charts (bubble, beeswarm), high-level, process, medallion, data flow, DP integration, DP security matrix, Sankey, fishbone, Wardley map, kanban, user journey, service blueprint, deployment, dependency graph, UML class, story map, or database schema diagrams as HTML/SVG/PNG, with .drawio, Mermaid, and .excalidraw import, plus lifecycle phase maps, block decomposition trees, and onboarding guidance.

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Command-line interface for CloudCompare — Agent-friendly harness for CloudCompare, the open-source 3D point cloud and mesh processing software. Supports 41 commands across 9 groups: project management, session control, point cloud operations (subsample, filter, segment, analyze), mesh operations, distance computation (C2C, C2M), transformations (ICP, matrix), export (LAS/LAZ/PLY/PCD/OBJ/STL/E57), and interactive REPL.

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Prepares bulk RNA-seq FASTQ, Salmon, STAR or featureCounts output for gene-level differential expression. Covers nf-core/rnaseq and standalone quantification, biological replication, strandedness, reference provenance, validated count assembly and a PyDESeq2 handoff. Use for FASTQ-to-counts analysis, nf-core/rnaseq configuration, STAR/Salmon quantification, or building a counts matrix for DESeq2. For single-cell data use scanpy; for statistical fitting alone use pydeseq2.

日本語の概要は準備中です。原文の説明を表示しています。

Prompt engineering regression test matrix register: baseline outputs, semantic drift thresholds, judge evaluations, and golden dataset.

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Export a promoted fine-tuned model in the right deployment format — merged safetensors, LoRA-only, GGUF with imatrix, or FP8. Use after a checkpoint passes promotion, when choosing a quantization format for a target device, or when an exported model fails its smoke test.

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Conduct a defensible cybersecurity risk assessment using the NIST SP 800-30 Rev 1 methodology: prepare scope and a risk model, identify threat sources and threat events, identify vulnerabilities and predisposing conditions, determine likelihood and impact, compute risk, and communicate results as a prioritized risk register. Use when an organization needs an actual risk *assessment* (not a maturity score), when a control framework (CSF, ISO 27001, RMF, SOC 2, PCI) requires a documented risk analysis as input, when leadership asks "what are our top risks and how bad are they", when assessing risk for a new system or major change, or when building a risk register from scratch. This is the methodology that feeds framework selection, ATO packages, and treatment decisions. Keywords: risk assessment, NIST 800-30, threat modeling, likelihood and impact, risk register, risk analysis, threat sources, vulnerabilities, risk determination, qualitative risk, risk matrix, residual risk, risk treatment.

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This skill outlines methodologies for performing authorized penetration testing against AWS, Azure, and GCP cloud environments. It covers understanding the shared responsibility model for testing scope, leveraging cloud-specific attack tools like Pacu and ScoutSuite, exploiting IAM misconfigurations, testing for SSRF to cloud metadata services, and reporting findings aligned to MITRE ATT&CK Cloud matrix.

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Find when and why tests broke on main: bisect a Swift package suite on CI across old commits, read the failure matrix, and decide per test whether the test went stale or the code regressed. Use when a suite is red on main, when PR CI only ran filtered tests and the full suite has drifted, or when asked which PR broke a test.

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Run tests on BrowserStack. Use when user mentions "browserstack", "cross-browser", "cloud testing", "browser matrix", "test on safari", "test on firefox", or "browser compatibility".

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Medical device risk management specialist implementing ISO 14971 throughout product lifecycle. Provides risk analysis, risk evaluation, risk control, and post-production information analysis. Use when user mentions risk management, ISO 14971, risk analysis, FMEA, fault tree analysis, hazard identification, risk control, risk matrix, benefit-risk analysis, residual risk, risk acceptability, or post-market risk.

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When the user wants to apply, document, or enforce brand guidelines for any product or company. Also use when the user mentions 'brand guidelines,' 'brand colors,' 'typography,' 'logo usage,' 'brand voice,' 'visual identity,' 'tone of voice,' 'brand standards,' 'style guide,' 'brand consistency,' or 'company design standards.' Covers color systems, typography, logo rules, imagery guidelines, and tone matrix for any brand — including Anthropic's official identity.

日本語の概要は準備中です。原文の説明を表示しています。