「mutations」の検索結果

Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

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Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.

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Locate CCSPlayerInventory::SendInventoryUpdateEvent in CS2 server.dll / libserver.so via IDA Pro MCP and emit a fresh, minimal-unique signature or offset for the WeaponPaints gamedata entry "CCSPlayerInventory::SendInventoryUpdateEvent" (symbol CCSPlayerInventory_SendInventoryUpdateEvent). Shortlist via functions constructing the inventory-full-update usermessage/event around m_pSOCache contents for the owning controller. The body packs the SO cache snapshot and sends it via the GC/usermessage path. Cross-check with callers in inventory-dirty flows (weapon paint mutations). Trigger: CCSPlayerInventory_SendInventoryUpdateEvent, CCSPlayerInventory::SendInventoryUpdateEvent

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Guide for when to use and when not to use return validators in Convex functions. Use this skill whenever the user is writing Convex queries, mutations, or actions and needs guidance on return value validation. Also trigger when the user asks about Convex type safety, runtime validation, AI-generated Convex code, Convex AI rules, Convex security best practices, or when they're debugging return type issues in Convex functions. Trigger this skill when users mention "validators", "returns", "return type", or "exact types" in the context of Convex development. Also trigger when writing or reviewing Convex AI rules or prompts that instruct LLMs how to write Convex code.

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Full-stack Convex development guidelines covering React, Vite, TypeScript, mutations, auth, design system, and documentation practices. Use when building features, writing Convex functions, or making code changes in this project.

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Create Convex queries, mutations, and actions with proper validation, authentication, and error handling. Use when implementing new API endpoints.

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Convex backend specialist. Use this agent for any code inside a `convex/` directory — function definitions, schemas, indexes, queries, mutations, actions, HTTP endpoints, cron jobs, file storage, auth wiring, and component installation. Knows the object-form function syntax, validator patterns, resource limits, and component ecosystem that generic Claude routinely gets wrong.

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Design and build reactive, type-safe, production-grade backends on Convex. Covers schema, queries/mutations/actions, indexes, auth, file storage, scheduling, real-time multiplayer, mobile backends, and LLM/agent workflows on Convex's one-platform stack.

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Detect typosquatting, homograph phishing, and brand impersonation domains using dnstwist to generate domain permutations and identify registered lookalike domains targeting your organization.

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Implements TanStack Query (React Query) for server state management with caching, mutations, optimistic updates, and infinite queries. Use when users request "react query", "tanstack query", "data fetching", "cache management", or "server state".

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Designs GraphQL schemas with types, queries, mutations, subscriptions, resolvers, and DataLoader patterns for efficient data fetching. Use when users request "GraphQL API", "schema design", "GraphQL setup", "resolvers", or "Apollo Server".

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Hunting skill for graphql vulnerabilities. Built from 12 public bug bounty reports across IDOR via node() / GID, mutation IDOR including AI/LLM features, cross-tenant IDOR, SSRF via argument, batching-DoS, query-cost-bypass, SQLi via argument, broken-object-level-authz, auth-bypass via unscoped mutations, and PII exposure from missing field-level authz. Use when hunting graphql on any target.

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Hunting skill for csrf vulnerabilities. Built from 15 public bug bounty reports including modern variants — SameSite=Lax sibling-subdomain bypass (Argo CD CVE-2024-22424), GraphQL mutations-via-GET (GitLab $3,370), framework-wide CSRF middleware disabled (Stripe Dashboard $5,000), path-traversal CSRF-token bypass (GitHub Enterprise CVE-2022-23732 $10k), Origin-omission bypass (TikTok $2,500), OAuth-state null-byte (Streamlabs), WebSocket CSRF / CSWSH (Coda), default-SameSite email-change → ATO (YoYo Games $400), social-account-link CSRF (HackerOne), JSON-CSRF via text/plain on email-change (TikTok $500). Use when hunting modern CSRF — heavy emphasis on chain-to-ATO patterns.

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Decides HOW to mutate a DAG when a node fails, quality is below threshold, or new information changes the plan. Selects from mutation strategies (add node, replace agent, fork paths, loop back, downgrade model) based on failure type, cost budget, and execution history. Activate on "DAG failed how to fix", "mutation strategy", "replan on failure", "adaptive DAG", "recovery strategy", "what to do when node fails". NOT for detecting failures (use dag-quality), executing mutations (use dag-planner), or runtime execution (use dag-runtime).

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