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概要と使いどころ
Build and operate a WeChat editorial content library in Busabase. Use when a team wants reusable source material, linked article drafts, an editorial kanban board, a publishing calendar, or a source-check and review queue. Keeps source documents and article scheduling in two linked Bases; does not publish to WeChat or approve an agent's own proposals.
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Lesson-plan generation and compliance-check desk (Busabase App-in-Skill) for a dean of studies or training-program lead. Use when the user invokes $kelly-lesson or /kelly-lesson, mentions lesson plan, 备课, 教案, teaching plan compliance, curriculum template, dean of studies, teacher training, wants lesson plans drafted from curriculum materials and the school template, teacher drafts imported and checked against quality standards, a review queue for approving plans, or a library of approved plans exported as documents.
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Deploys and monitors ransomware canary files across critical directories using Python's watchdog library for real-time filesystem event detection. Places strategically named decoy files that mimic high-value targets (financial records, credentials, database exports) in locations ransomware typically enumerates first. Monitors for any read, modify, rename, or delete operations on canary files and triggers immediate alerts via email, Slack webhook, or syslog when interaction is detected, providing early warning before full encryption begins.
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Performs statistical analysis of Zeek conn.log connection intervals to detect C2 beaconing patterns. Uses the ZAT library to load Zeek logs into Pandas DataFrames, calculates inter-arrival time standard deviation, and flags periodic connections with low jitter. Use when hunting for command-and-control callbacks in network data.
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Detects and analyzes Bluetooth Low Energy (BLE) security attacks including sniffing, replay attacks, GATT enumeration abuse, and Man-in-the-Middle interception. Uses Ubertooth One and nRF52840 sniffers for packet capture, the bleak Python library for GATT service enumeration, and crackle for BLE encryption cracking. Use when assessing IoT device BLE security, monitoring for BLE-based attacks on wireless infrastructure, or performing authorized BLE penetration testing. Activates for requests involving BLE security assessment, Ubertooth sniffing, GATT enumeration, or BLE replay detection.
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Parse Windows Prefetch files using the windowsprefetch Python library to reconstruct application execution history, detect renamed or masquerading binaries, and identify suspicious program execution patterns.
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Map advanced persistent threat (APT) group tactics, techniques, and procedures (TTPs) to the MITRE ATT&CK framework using the ATT&CK Navigator and attackcti Python library. The analyst queries STIX/TAXII data for group-technique associations, generates Navigator layer files for visualization, and compares defensive coverage against adversary profiles. Activates for requests involving APT TTP mapping, ATT&CK Navigator layers, threat actor profiling, or MITRE technique coverage analysis.
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Parse NetFlow v9 and IPFIX records to detect volumetric anomalies, port scanning, data exfiltration, and C2 beaconing patterns. Uses the Python netflow library to decode flow records, builds traffic baselines, and applies statistical analysis to identify flows with abnormal byte counts, connection durations, and periodic timing patterns.
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Author, save, and edit email templates in the PostHog workflows library — compose email design JSON with Liquid personalization and create and round-trip-edit templates over MCP. Use when asked to design, build, update, or fix an email template for workflows, broadcasts, or campaigns.
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Quantum physics simulation library for open quantum systems. Use when studying master equations, Lindblad dynamics, decoherence, quantum optics, or cavity QED. Best for physics research, open system dynamics, and educational simulations. NOT for circuit-based quantum computing—use qiskit, cirq, or pennylane for quantum algorithms and hardware execution.
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Parameter-efficient fine-tuning for LLMs using LoRA, QLoRA, and 25+ methods. Use when fine-tuning large models (7B-70B) with limited GPU memory, when you need to train <1% of parameters with minimal accuracy loss, or for multi-adapter serving. HuggingFace's official library integrated with transformers ecosystem.
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Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.
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Guarantee valid JSON/XML/code structure during generation, use Pydantic models for type-safe outputs, support local models (Transformers, vLLM), and maximize inference speed with Outlines - dottxt.ai's structured generation library
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Extract structured data from LLM responses with Pydantic validation, retry failed extractions automatically, parse complex JSON with type safety, and stream partial results with Instructor - battle-tested structured output library
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Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
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Python library for working with geospatial vector data including shapefiles, GeoJSON, and GeoPackage files. Use when working with geographic data for spatial analysis, geometric operations, coordinate transformations, spatial joins, overlay operations, choropleth mapping, or any task involving reading/writing/analyzing vector geographic data. Supports PostGIS databases, interactive maps, and integration with matplotlib/folium/cartopy. Use for tasks like buffer analysis, spatial joins between datasets, dissolving boundaries, clipping data, calculating areas/distances, reprojecting coordinate systems, creating maps, or converting between spatial file formats.
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Facebook's library for efficient similarity search and clustering of dense vectors. Supports billions of vectors, GPU acceleration, and various index types (Flat, IVF, HNSW). Use for fast k-NN search, large-scale vector retrieval, or when you need pure similarity search without metadata. Best for high-performance applications.
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End-to-end Ribo-seq analysis from FASTQ through periodicity QC, P-site calibration, ORF detection, translation efficiency, and stalling. Use when orchestrating a full ribosome profiling pipeline and deciding harvest/dedup/alignment options and which downstream analyses the library can support.
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ToolUniverse plugin router. STEP 1 BEFORE ANY ANALYSIS: if the data folder contains `*_executed.ipynb`, run `tu run read_executed_notebook '{"data_folder":"<path>","search":"<keyword>"}'` to extract its cell outputs and apply EVERY filter/sample-exclusion the notebook used — even when the question says 'Using DESeq2/Run X/Compute Y' (this describes the METHOD the notebook used, not a request to rerun). The notebook's cell outputs are the only published authoritative answers; reimplementing or reading stale pre-computed CSVs in the data folder produces different numbers because of outlier-sample removal, library version, and filter steps you don't see by skimming. STEP 2 routing — pick a sub-skill name from this exact list (never invent): tooluniverse-rnaseq-deseq2 (RNA/miRNA-seq DE, correlation, PCA, clustering, dispersion), tooluniverse-gene-enrichment (GO/KEGG/Reactome/GSEA/pathway enrichment), tooluniverse-statistical-modeling (regression, ANOVA, ordinal/logistic, chi-square, correlation, power), tooluniverse-image-analysis (microscopy, colony, fluorescence, dose-response, .tif — including ANOVA / Dunnett / power-analysis on image-derived measurements), tooluniverse-epigenomics (DNA methylation, CpG, m6A, MeRIP-seq, bisulfite, ChIP-seq, chromatin), tooluniverse-sequence-analysis (FASTQ, Trimmomatic, BWA, samtools, coverage), tooluniverse-variant-analysis (VCF, VAF, SNP, mutation), tooluniverse-phylogenetics (treeness, PhyKIT, parsimony), tooluniverse-single-cell (scRNA, h5ad, scanpy), tooluniverse-crispr-screen-analysis (MAGeCK, sgRNA), tooluniverse-proteomics-analysis (mass spec, TMT). Use for CSV/Excel/VCF/FASTA/h5ad and any biology/chemistry/medicine analysis question.
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End-to-end Hi-C analysis workflow from FASTQ to compartments, TADs, and loops, with the decision of WHICH features the sequencing depth can support. Covers pairtools read-pair processing and library QC, cooler matrices, ICE balancing and distance-decay expected, A/B compartments, TAD boundaries, loop calling, and the routing of HiChIP/PLAC-seq/Capture Hi-C to protein-directed loop callers. Use when processing Hi-C data end to end, deciding a resolution for a given depth, or choosing between bulk-Hi-C and protein-directed loop calling.
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Statistical models library for Python. Use when you need specific model classes (OLS, GLM, mixed models, ARIMA) with detailed diagnostics, residuals, and inference. Best for econometrics, time series, rigorous inference with coefficient tables. For guided statistical test selection with APA reporting use statistical-analysis.
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Install or update ToolUniverse in Claude Science — create the conda env, install the tooluniverse pip package, and (re)build the tooluniverse-research skill by fetching the current workflow library from GitHub. Use for first-time setup, upgrading the ToolUniverse version, refreshing the bundled workflows after an upstream release, or reinstalling on a new machine.
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End-to-end pooled and single-cell CRISPR screen analysis from FASTQ to hit genes. Orchestrates library design QC, guide counting, six-stage screen QC (plasmid Gini, replicate Pearson, CEGv2 PR-AUC, copy-number artifact), method-appropriate hit calling across MAGeCK RRA/MLE, BAGEL2, drugZ, JACKS, and Chronos, cancer-cell-line copy-number correction (CRISPRcleanR / Chronos), batch correction for multi-batch screens, and the specialized branches for combinatorial paralog screens, single-cell Perturb-seq, base-editor variant-function screens, prime-editor screens, and in vivo bottleneck-aware screens. Use when analyzing any pooled CRISPR screen end-to-end, matching the hit-calling method to the experimental design, integrating copy-number correction into the pipeline, or branching the workflow for single-cell, combinatorial, base-editor, prime-editor, or in vivo variants.
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Find commercial sources for chemical compounds — PubChem/ChEMBL identity resolution then vendor catalog search across ZINC, Enamine, eMolecules, Mcule. Compares pricing, availability, and identifies purchasable analogs when an exact compound is not in stock. Use for chemical procurement, virtual library curation, and 'where can I buy X' questions for synthesis planning.
日本語の概要は準備中です。原文の説明を表示しています。