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Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.

日本語の概要は準備中です。原文の説明を表示しています。

Performs 3D shape-based similarity searching using ROCS (OpenEye), USRCAT (ultra-fast), Open3DAlign (RDKit), ESPSim (electrostatic), and ShaEP with explicit handling of Tanimoto-Combo (shape + color), shape vs ECFP4 complementarity, conformer-ensemble searching, alignment optimization, and scaffold hopping. Use when searching for shape-mimicking compounds with different scaffolds, identifying bioisosteric replacements, prospective scaffold hopping, or expanding hit series beyond 2D similarity.

日本語の概要は準備中です。原文の説明を表示しています。

Performs structure-based virtual screening using AutoDock Vina, SMINA, GNINA (CNN scoring), and DiffDock-L hybrid workflows with explicit choice rules across rigid vs flexible docking, cross-docking vs self-docking, binding-site detection (P2Rank, fpocket), receptor preparation (PDB2PQR, PROPKA), ligand preparation (meeko, OpenBabel), and ultralarge-library screening (ZINC22, Enamine REAL). Use when screening chemical libraries against a protein target to find candidate binders, ranking docking poses, or selecting a docking workflow for a specific scenario.

日本語の概要は準備中です。原文の説明を表示しています。

VenTu is a static export on GitHub Pages — no Node runtime at request time. Use when adding routes, auth, alerts, forms, API endpoints, or anything that could depend on a server.

日本語の概要は準備中です。原文の説明を表示しています。

Move entities through containers, hands, slots, storage, equipment, and inventories without corrupting ownership or transforms.

日本語の概要は準備中です。原文の説明を表示しています。

Validate UI, command, text, numeric, entity, and configuration input with localized feedback and server authority.

日本語の概要は準備中です。原文の説明を表示しています。

Spawn, initialize, replace, transfer, and delete entities without breaking lifecycle, transforms, containers, or ownership.

日本語の概要は準備中です。原文の説明を表示しています。

Implement or modify web UI in React, Next.js, or Angular. Use for components, pages, styles, forms, and frontend state or data flows.

日本語の概要は準備中です。原文の説明を表示しています。

When the user wants help with paid advertising campaigns on Google Ads, Meta (Facebook/Instagram), LinkedIn, Twitter/X, or other ad platforms. Also use when the user mentions 'PPC,' 'paid media,' 'ad copy,' 'ad creative,' 'ROAS,' 'CPA,' 'ad campaign,' 'retargeting,' or 'audience targeting.' This skill covers campaign strategy, ad creation, audience targeting, and optimization.

日本語の概要は準備中です。原文の説明を表示しています。

When the user wants help creating, scheduling, or optimizing social media content for LinkedIn, Twitter/X, Instagram, TikTok, Facebook, or other platforms. Also use when the user mentions 'LinkedIn post,' 'Twitter thread,' 'social media,' 'content calendar,' 'social scheduling,' 'engagement,' or 'viral content.' This skill covers content creation, repurposing, and platform-specific strategies.

日本語の概要は準備中です。原文の説明を表示しています。

Extract property address, price, room count, and features from a listing document into structured JSON for MLS and property platforms.

日本語の概要は準備中です。原文の説明を表示しています。

Extract employee, department, expense lines, tax, totals, and approval fields from Japanese expense settlement forms.

日本語の概要は準備中です。原文の説明を表示しています。

Records a running CARLA simulation to a .log file via start_recorder/stop_recorder for later deterministic replay — capturing actor spawns, transforms, traffic-light states and animations (optionally velocities/controls). Use when the user asks to "record the simulation", "start/stop the recorder", "capture this run", or "save a scenario to replay later". Does NOT capture sensor images.

日本語の概要は準備中です。原文の説明を表示しています。

Deploy Adobe-powered applications to Vercel, Cloud Run, and Adobe App Builder with proper credential injection and health monitoring. Use when deploying Adobe API integrations to production platforms. Trigger with phrases like "deploy adobe", "adobe Vercel", "adobe Cloud Run", "adobe App Builder deploy", "adobe production deploy".

日本語の概要は準備中です。原文の説明を表示しています。

Cross-platform creative quality audit covering ad copy, video, image, and format diversity across all platforms. Detects creative fatigue, evaluates platform-native compliance, and provides production priorities. Use when user says creative audit, ad creative, creative fatigue, ad copy, ad design, or creative review.

日本語の概要は準備中です。原文の説明を表示しています。

Download and transcribe videos from YouTube, Bilibili, TikTok and 1000+ platforms. Use when user requests video download, transcription (转录/字幕提取), or converting video to text/markdown. Supports quality selection, audio extraction, playlist downloads, cookie-based authentication, and AI-powered transcription via SiliconFlow API (免费转录).

日本語の概要は準備中です。原文の説明を表示しています。

Design, audit, and improve accessibility and inclusive user experiences. Use when Codex is asked about WCAG, keyboard navigation, focus states, screen readers, ARIA, contrast, captions, reduced motion, forms, semantic HTML, accessible UI, game accessibility, inclusive design, accessibility QA, or compliance-sensitive accessibility work.

日本語の概要は準備中です。原文の説明を表示しています。

Build WCAG 2.1 AA compliant web applications for University of Sheffield. Covers semantic HTML, ARIA patterns, form accessibility, keyboard navigation, color contrast, alt text, captions, and automated testing. Use when creating websites, web apps, forms, interactive components, or auditing accessibility for WCAG compliance, screen readers, keyboard access, or inclusive design.

日本語の概要は準備中です。原文の説明を表示しています。

Mobile accessibility testing skill for WCAG compliance, VoiceOver/TalkBack validation, dynamic type support, color contrast analysis, and accessibility auditing across iOS and Android platforms.

日本語の概要は準備中です。原文の説明を表示しています。

Auto-invoke when reviewing JSX with interactive elements, forms, buttons, or navigation. Enforces WCAG compliance and inclusive design.

日本語の概要は準備中です。原文の説明を表示しています。

Creates high-quality content (blog posts, tweets, newsletters, documentation) that matches the user's writing style and voice. Performs web research to find citations and supporting evidence. Use when user requests blog posts, marketing content, newsletters, tweets, or any written content that should sound authentic and be well-researched.

日本語の概要は準備中です。原文の説明を表示しています。

SSL/БСП subsystems guidance and search via 1c-mcp_ssl_server MCP. Use when working with standard library subsystems - users, files, print forms, background jobs, email, common utilities.

日本語の概要は準備中です。原文の説明を表示しています。

Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.

日本語の概要は準備中です。原文の説明を表示しています。

Performs proximity operations on genomic intervals with bedtools (closest, window, flank, slop) and pybedtools - nearest-feature queries with signed/strand-aware distance, fixed-radius window searches, strand-aware promoter construction, and interval extension. Covers the closest -d/-D a/b/ref/-t/-k/-io/-iu/-id flags, the -D ref strand sign-flip, silent chromosome-end clipping in slop/flank, -t all tie double-counting, and the critical distinction between a geometry answer (nearest TSS) and a biology answer (which gene an element regulates). Use when assigning peaks or variants to genes, defining promoters from a gene model, building distance-to-TSS distributions, finding features within a window, or extending intervals - and when deciding whether nearest-gene is a fair prior (GWAS locus) or a trap (distal enhancer).

日本語の概要は準備中です。原文の説明を表示しています。