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Designs cell-based and animal-based validation plans that translate computational, omics, biomarker, genetic, or clinical findings into experimentally testable validation routes. Always use this skill whenever a user wants to move from an in silico, statistical, or clinical association finding toward wet-lab validation using cell systems, organoid-like systems, xenograft or genetically relevant animal models. It should define the exact claim to test, separate mechanism-testing from association-support and translational-support goals, choose the best-fit model family, specify perturbation strategy, readouts, controls, sequencing of experiments, and four workload configurations (Lite / Standard / Advanced / Publication+) with one recommended primary plan. Never fabricate model availability, reagent availability, species relevance, assay feasibility, phenotype penetrance, expected effect sizes, validation success, or literature references.

日本語の概要は準備中です。原文の説明を表示しています。

Detects methodological gaps across study design, analysis, validation, bias control, reproducibility, and implementation readiness within a biomedical research area. Use this skill when a user wants to identify what current studies are still methodologically missing, which weaknesses are most consequential, and what upgrade path would produce a stronger next-step study. Always separate design gaps, analysis gaps, validation gaps, and reproducibility gaps. Never treat technical complexity as methodological rigor.

日本語の概要は準備中です。原文の説明を表示しています。

A medical-research-native literature reading skill for users with clinical, bioinformatics, translational, and basic experimental backgrounds. Use this skill whenever a user wants to read, analyze, critique, or interpret a medical or scientific paper — whether they provide a PDF, abstract, DOI, PMID, or just a title. Triggers include requests like \"analyze this paper\", \"critique this study\", \"is this a strong paper?\", \"give me similar studies\", \"prepare me for journal club\", \"help me understand this bioinformatics paper\", \"what are the weaknesses here?\", or \"turn this into a mind map\". Also activate for any downstream deliverables such as journal club kits, comparison tables, PI decision briefs, replication starters, or follow-up experiment designs. Do NOT treat as a generic summarizer — this skill performs structured evidence-type classification, track-specific critical appraisal, interpretation-boundary judgment, and research-grade follow-up generation.

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Ranks papers by evidence family, methodological quality tier, validation depth, and claim discipline; assigns anchor, context-setting, mechanistic support, or caution citation roles; prevents prestige-based or design-label-based ranking errors.

日本語の概要は準備中です。原文の説明を表示しています。

Use when estimating relative immune cell infiltration from a bulk expression matrix with a CIBERSORT-style nu-SVR deconvolution workflow based on an LM22 signature matrix, comparing one case group against one control group, and generating structured tables plus immune-fraction plots. NOT for single-cell RNA-seq, spatial data, clinical diagnosis, or workflows that require the original hosted CIBERSORT web service.

日本語の概要は準備中です。原文の説明を表示しています。

Review XQUIC harness structure for bloat, duplicated facts, trigger overlap, reference drift, and missing hard checks. Use when changing AGENTS.md, harness specs, pipelines, skills, setup scripts, validation routing, or when asked to audit harness design.

日本語の概要は準備中です。原文の説明を表示しています。

Emulated Google OAuth 2.0, OpenID Connect, Gmail, Calendar, and Drive for local development and testing. Use when the user needs to test Google sign-in locally, emulate OIDC discovery, handle Google token exchange, configure Google OAuth clients, work with Gmail messages/drafts/threads/labels, manage Calendar events, upload or list Drive files, or work with Google userinfo without hitting real Google APIs. Triggers include "Google OAuth", "emulate Google", "mock Google login", "test Google sign-in", "OIDC emulator", "Google OIDC", "Gmail API", "Google Calendar", "Google Drive", "local Google auth", or any task requiring a local Google API.

日本語の概要は準備中です。原文の説明を表示しています。

Emulated AWS cloud services (S3, SQS, Cognito, IAM, STS) for local development and testing. Use when the user needs to interact with AWS API endpoints locally, test S3 bucket and object operations, emulate SQS queues and messages, test Cognito sign-up, sign-in, JWTs, or Identity Pools, manage IAM users/roles/access keys, test STS assume role, or work without hitting real AWS APIs. Triggers include "AWS emulator", "emulate AWS", "mock S3", "local SQS", "test IAM", "emulate S3", "AWS locally", "STS assume role", or any task requiring local AWS service emulation.

日本語の概要は準備中です。原文の説明を表示しています。

Redesign GitHub README homepages or create project-native pure SVG, hybrid SVG-composed PNG/WebP, and opt-in animated GIF assets. Use when a user asks to beautify, redesign, rebrand, visually upgrade, simplify, or audit a GitHub README; create only a hero, section headers, diagrams, badges, motion graphics, showcase modules, or other README assets; or turn a repository homepage into a cohesive visual story. If whole-README work versus asset-only work is unclear, ask which scope the user wants. For hero-like assets where pure SVG and generated raster material are both viable, explain the tradeoffs and confirm the implementation before creating the asset.

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Use this skill when creating database schemas or tables for Timescale, TimescaleDB, TigerData, or Tiger Cloud, especially for time-series, IoT, metrics, events, or log data. Use this to improve the performance of any insert-heavy table. **Trigger when user asks to:** - Create or design SQL schemas/tables AND Timescale/TimescaleDB/TigerData/Tiger Cloud is available - Set up hypertables, compression, retention policies, or continuous aggregates - Configure partition columns, segment_by, order_by, or chunk intervals - Optimize time-series database performance or storage - Create tables for sensors, metrics, telemetry, events, or transaction logs **Keywords:** CREATE TABLE, hypertable, Timescale, TimescaleDB, time-series, IoT, metrics, sensor data, compression policy, continuous aggregates, columnstore, retention policy, chunk interval, segment_by, order_by Step-by-step instructions for hypertable creation, column selection, compression policies, retention, continuous aggregates, and indexes.

日本語の概要は準備中です。原文の説明を表示しています。

Configure code signing for macOS and Windows binaries with notarization.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "plan team structure", "determine hiring needs", "design org chart", "calculate compensation", "plan equity allocation", or requests organizational design and headcount planning for a startup.

日本語の概要は準備中です。原文の説明を表示しています。

Design multi-stage CI/CD pipelines with approval gates, security checks, and deployment orchestration. Use when architecting deployment workflows, setting up continuous delivery, or implementing GitOps practices.

日本語の概要は準備中です。原文の説明を表示しています。

Half-hour television comedy craft (半小时情景喜剧/笑点力学/困境机器/多机位单机位格式) — merged from Evan S. Smith's Writing Television Sitcoms (premise-driven comedy in three levels, nine predicaments, six character mixes, setup/punchline mechanics, toppers, running gags, ten comedic nuances, format rules), Neil Landau's sitcom seven-step formula and comedy-room models, Richard Blum's act-length and set-count parameters, Phoebe Waller-Bridge's Fleabag scripts (direct address as a season-long device, six-episode skeleton), Pamela Douglas on dramedy, Kam Miller on complementary comic traits, and Jesse Armstrong on jokes carrying tragedy. Use when writing or fixing a sitcom episode or spec, raising joke density per page, designing a comic predicament that generates stories, choosing between multi-camera and single-camera format and page counts, structuring cold open/acts/tag, writing a half-hour pilot, running a comedy punch-up, or making a drama funny without shifting genre.

日本語の概要は準備中です。原文の説明を表示しています。

Interview the user relentlessly about a plan, design, or topic, checkpointing every answer to a brainstorm file so nothing is lost. Use when the user wants to stress-test a plan, get grilled on a design, run a brainstorm or discovery session, extract what's in their head into a doc, build up their AI OS context over time, or says "grill me".

日本語の概要は準備中です。原文の説明を表示しています。

AI DevKit · Implementation phase guidance for executing feature plans and checking implementation against design. Use when the user wants to implement planned tasks, update implementation docs, verify code matches design, or run dev-lifecycle phases 5 and 7.

日本語の概要は準備中です。原文の説明を表示しています。

Debug live Azure Kubernetes Service (AKS) incidents with a read-only, evidence-first investigation. WHEN: pod crashes or Pending, CrashLoopBackOff, OOMKilled, ImagePullBackOff, node NotReady, DNS or ingress failure, connectivity timeout, network policy, SNAT exhaustion, node-pool scaling blocked by QuotaExceeded or InsufficientVCPUQuota, upgrade stuck, spot or zone disruption, a bare VMExtensionProvisioningError or AllocationFailed wrapper, an uncataloged capacity symptom, or 'investigate my AKS cluster'. DO NOT USE FOR: packet capture (use aks-network-capture); GPU or model-serving issues (use aks-gpu-inference); cluster creation or provisioning (use azure-kubernetes); cost (use cost-analysis from the optional azure-cost plugin); pod rightsizing (use azure-kubernetes); a fully qualified documented AKS signature with every required nested qualifier (use aks-known-issues); standalone failures on non-AKS Azure resources (use azure-diagnostics). Unqualified errors and open-ended incidents stay here only for AKS.

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Architect and provision enterprise Azure infrastructure from workload descriptions. For cloud architects and platform engineers planning networking, identity, security, compliance, and multi-resource topologies with WAF alignment. Generates Bicep or Terraform directly (no azd). WHEN: 'plan Azure infrastructure', 'architect Azure landing zone', 'design hub-spoke network', 'plan multi-region DR topology', 'set up VNets firewalls and private endpoints', 'subscription-scope Bicep deployment', 'Azure Backup for VM workloads'. PREFER azure-prepare FOR app-centric workflows.

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Build, deploy, evaluate, optimize, fine-tune, and manage Microsoft Foundry agents, models, and resources end to end. USE FOR: foundry, azd ai agent, azd provision/deploy, hosted agent scaffold/develop/run/deploy/troubleshoot, prompt agent create, managed harness agent create, GitHub Copilot harness agent, create agent, update agent, add tool to agent, invoke agent, agent insights, evaluate agent, batch eval, continuous eval, continuous monitoring, agent CI/CD, optimize prompt, improve prompt, optimize agent instructions, Agent Optimizer scaffold, dataset curation from traces, deploy model, model fine-tuning (SFT/DPO/RFT), Foundry project, RBAC, role assignment, permissions, quota, capacity, region, deployment failure, AI Services, create Foundry resource, knowledge index, customize deployment, onboard, availability, training-data, grader, distillation, large file upload. DO NOT USE FOR: Azure Functions, App Service, general Azure deploy (use azure-deploy), general Azure prep (use azure-prepare).

日本語の概要は準備中です。原文の説明を表示しています。

Use C#/.NET in Godot 4.7: partial classes extending nodes, the PascalCase lifecycle (_Ready/_Process/_PhysicsProcess), [Export] fields, [Signal] delegates as C# events, type-safe node lookup, and calling between C# and GDScript. Use when writing Godot game code in C# (.cs files, .csproj), needing the Godot .NET build, converting GDScript patterns to C#, or wiring Godot signals as C# events.

日本語の概要は準備中です。原文の説明を表示しています。

Audit Git configuration with one read-only baseline command, then propose confirmed, non-destructive fixes for identity, editor, and diff and merge tooling, with signing and safe.directory help only on request. Use when setting up or checking Git on a workstation.

日本語の概要は準備中です。原文の説明を表示しています。

Design evaluation datasets and supporting documentation for AI systems and agents, covering the scoping interview, difficulty distribution, dataset contract, sample review, and metric and tooling selection. Use when building or reviewing an evaluation set for a conversational agent, assistant, or retrieval-grounded AI system.

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Audit a landing page or funnel step and produce a prioritised CRO test plan. Use when asked to improve conversion rate, audit a landing/signup/checkout page, reduce funnel drop-off, or plan A/B tests for a page. Produces a CRO plan — a heuristic conversion audit, the diagnosed friction, prioritised test hypotheses (ICE), test designs with sample-size math, and the measurement guardrails.

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Write a client case study that sells future work — challenge, approach, results. Use when asked to write a case study, a client success story, a project write-up, or a portfolio case for consulting/agency work. Produces a results-led case study — the client & challenge, your approach, quantified outcomes, a client quote slot, and a takeaway — structured to win the next client. Ready to export as a designed PDF.

日本語の概要は準備中です。原文の説明を表示しています。