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概要と使いどころ
Design statistically rigorous A/B tests for product features, UI changes, onboarding flows, and pricing experiments. Use when asked to set up an experiment, design an A/B test, calculate sample size, or interpret test results. Produces a complete test plan with hypothesis, variant definitions, sample size, duration estimate, guardrail metrics, and a results interpretation guide.
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Assess whether and how someone can safely stay in their own home as they age — the home hazards, the support gaps, and the modifications and services that make it work. Use when asked can my parent stay in their home safely, aging in place assessment, is it safe for them to live alone, or what do we need for them to stay home. Produces a room-by-room safety read (fall hazards, accessibility), an honest look at the daily-living and support gaps, the modifications and services that could close them, warning signs that home may no longer be safe, and how to raise it respectfully — helping a family make a clear-eyed, dignity-preserving decision. Not medical advice.
日本語の概要は準備中です。原文の説明を表示しています。
Help users design and execute a high-signal interview process that prioritizes real-world performance over superficial charisma or pedigree.
日本語の概要は準備中です。原文の説明を表示しています。
Designs and implements testing strategies for any codebase. Use when adding tests, improving coverage, setting up testing infrastructure, debugging test failures, or when asked about unit tests, integration tests, or E2E testing.
日本語の概要は準備中です。原文の説明を表示しています。
SERP-based semantic topic clustering for content architecture planning. Groups keywords by actual Google SERP overlap (not text similarity), designs hub-and-spoke content clusters with internal link matrices, and generates interactive visualizations. Optionally executes content creation if claude-blog is installed. Use when user says "topic cluster", "content cluster", "semantic clustering", "pillar page", "hub and spoke", "content architecture", "keyword grouping", or "cluster plan".
日本語の概要は準備中です。原文の説明を表示しています。
Extract leads from conferences, meetups, hackathons, and podcasts by analyzing speaker lists, sponsor lists, hackathon entries, and podcast guests. Discovers events via Sessionize, Confs.tech, Meetup, Luma, ListenNotes, and Devpost. Looks back 90 days and forward 180 days.
日本語の概要は準備中です。原文の説明を表示しています。
Extract leads from competitor product activity — Product Hunt commenters/upvoters, HN posts about competitors, case studies, testimonials, tech press, and switching signals. Detects people actively switching from competitors as highest-priority leads.
日本語の概要は準備中です。原文の説明を表示しています。
Monitor existing customer accounts for upsell and cross-sell signals: team growth on LinkedIn, new job postings, product usage patterns, funding announcements, and public company news. Produces a weekly expansion opportunity list with context and talk tracks. Chains web search, LinkedIn profile monitoring, and job posting detection.
日本語の概要は準備中です。原文の説明を表示しています。
Set up a complete outbound email campaign in Smartlead. Asks the user for campaign goal, audience, messaging, schedule, and mailbox allocation. Creates the campaign, adds leads, saves email sequences, sets schedule, and assigns available mailboxes. Use when a user wants to launch email outreach via Smartlead.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end cold email outreach orchestration. Handles goal alignment, lead ingestion from any source (CSV, paste, CRM export, database), sequence design, email generation, campaign setup in the user's chosen outreach tool, and launch. Tool-agnostic — supports Smartlead (full MCP automation), Instantly, Lemlist, Apollo, or manual CSV export.
日本語の概要は準備中です。原文の説明を表示しています。
Assemble a ChatGPT chat-reveal video ad from a thread + timeline JSON — one continuous Playwright recording of a ChatGPT mobile chat (user types with the iOS keyboard up → taps send → keyboard slides down + header cluster swaps in one beat → one gray loading dot → the assistant answer streams in word-by-word) crossfaded into a designed end card, with subliminal ChatGPT SFX and an optional ducked music bed. FREE assembly (Playwright + ffmpeg); the recipe supplies the per-brand thread + timeline + end-card config and gates the paid music call to its own capability. The ChatGPT sibling of render-imessage-chat. Use for the chatgpt-chat format.
日本語の概要は準備中です。原文の説明を表示しています。
Synthesize new waveforms from scratch for Simulink inports using createInputDataset. Use ONLY when the user asks to generate, create, or synthesize signals (step, ramp, sine, chirp, pulse, noise) to populate a Dataset for External Inputs or Signal Editor. Covers timeseries and timetable formats with correct data type, interpolation, units, and dimensions. Also covers function-call and trigger inport timing setup. Do NOT use when the user wants to load, import, or read existing data from files (MAT, CSV, spreadsheet) — even if that data will be used as model input. Do NOT use for running simulations or plotting outputs.
日本語の概要は準備中です。原文の説明を表示しています。
Add, configure, and manage faults on Simulink, Simscape, and System Composer model signals for robustness analysis and safety validation. Use when injecting faults (stuck, noise, gain, offset) onto block inports/outports, enabling fault simulation, or analyzing fault effects. Covers sensor failures, signal corruptions, actuator faults, FMEA validation, and robustness testing. Requires Simulink Fault Analyzer.
日本語の概要は準備中です。原文の説明を表示しています。
Use when a Simulink model is incompatible with Simulink Design Verifier (sldvcompat returns false, or an SLDV analysis errors out on an unsupported construct) and needs to be made analyzable. Diagnoses the incompatibility, applies the matching fix to a copy, and confirms the copy is compatible; optionally raises confidence the fix preserved behavior via a back-to-back consistency replay (agreement on the generated tests, not a proof of equivalence). Do NOT use for running test generation, design error detection, or requirement verification themselves — only for making a model compatible so those can proceed.
日本語の概要は準備中です。原文の説明を表示しています。
Building or editing Simulink (.slx) models that stream signals in frames using DSP System Toolbox — audio, vibration, radar, comms. Use when the prompt names a Simulink block (Discrete FIR Filter, Buffer, Unbuffer, Rate Transition, Downsample, Upsample, Sample-Rate Converter, FIR Decimation, Time Scope, Spectrum Analyzer, From Multimedia File) or an action (frame-based processing, InputProcessing, buffering, overlap, windowing, STFT, short-time Fourier, decimate, downsample, upsample, resample, multirate, anti-aliasing, tunable filter). Prevents silent numerical errors from sample-vs-frame mismatch, wrong block choice, or missing anti-aliasing.
日本語の概要は準備中です。原文の説明を表示しています。
Calls significant loops from protein-directed and targeted 3C assays (HiChIP, PLAC-seq, Capture Hi-C/PCHi-C, ChIA-PET) where the contact background is peak-anchored and coverage-biased, so generic Hi-C loop callers (cooltools dots, Juicer HiCCUPS) use the wrong null. Covers FitHiChIP (config-driven coverage+distance-decay spline regression, peak-to-peak vs peak-to-all foreground, loose vs stringent background, coverage vs ICE bias), MAPS (positive Poisson regression on bias factors for PLAC-seq/HiChIP), hichipper (restriction-site-distance bias model + library QC), CHiCAGO (Delaporte two-component Brownian+technical background for asymmetric bait x other-end Capture Hi-C), the with/without separate-ChIP anchor decision, and differential loops via diffloop. Use when calling loops from HiChIP/PLAC-seq/Capture Hi-C, choosing FitHiChIP/MAPS/CHiCAGO, picking peak-to-all vs peak-to-peak, setting the loop FDR, supplying ChIP peaks as anchors, QCing a HiChIP library, or comparing loops between conditions.
日本語の概要は準備中です。原文の説明を表示しています。
Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.
日本語の概要は準備中です。原文の説明を表示しています。
Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.
日本語の概要は準備中です。原文の説明を表示しています。
Treats a ctDNA assay as a molecule-counting experiment at the Poisson edge and builds its analytical-validation case the measurement-science way. Covers the genome-equivalent currency (~330 haploid copies/ng), the lambda = input_GE x VAF sampling ceiling (lambda>=3 for ~95% detection), the error-suppression ladder (raw NGS ~1e-3 -> single-strand UMI ~1e-4/1e-5 -> duplex <1e-7), the CLSI EP17 LoB/LoD/LoD95/LoQ framework, the per-locus-vs-panel-integrated LoD distinction that lets bespoke MRD reach ppm, contrived/SEQC2 reference standards, and honest LoD reporting conditioned on input mass + consensus depth + replicate detection rate. Use when stating or trusting a sensitivity claim, designing a dilution-series validation, deciding how many genome equivalents are needed at a target VAF, choosing a single-locus vs panel-integrated LoD, or auditing a "detects 0.1% VAF" claim.
日本語の概要は準備中です。原文の説明を表示しています。
Generates, normalizes, and converts bedGraph signal tracks (4-column chrom/start/end/value, 0-based half-open) with bedtools genomecov, deepTools bamCoverage/bamCompare/bigwigCompare, bedtools unionbedg, and UCSC bedGraphToBigWig. Covers why a raw coverage bedGraph is not comparable across samples until normalized, the CPM/RPKM/BPM/RPGC normalization menu and the conserved-total assumption that makes them wrong under a global perturbation, the strict sorted-non-overlapping-chrom.sizes bedGraphToBigWig contract that silently corrupts a bigWig, effective-genome-size selection, and bin-size aliasing. Use when building or normalizing a coverage/signal track from a BAM, comparing tracks across samples or conditions, converting bedGraph to a browser-ready bigWig, or diagnosing a track that looks plausible but reports wrong heights.
日本語の概要は準備中です。原文の説明を表示しています。
Differential abundance (DA) and differential state (DS) analysis for flow and mass cytometry - tests which cell populations change in frequency or marker expression between conditions using diffcyt (edgeR/voom/GLMM for DA, limma/LMM for DS), with cydar, CITRUS, and compositional methods (sccomp, scCODA, DCATS) as alternatives. Covers the sample-is-the-experimental-unit principle, design/contrast and mixed-model formulas, compositionality of cluster proportions, and FDR across clusters. Use when comparing populations between groups, choosing a DA method, handling paired/batch designs, or deciding whether compositional correction is needed.
日本語の概要は準備中です。原文の説明を表示しています。
Add p-value brackets, significance asterisks, and effect-size annotations to distribution plots using ggpubr, ggsignif, and statannotations with correct test selection (parametric vs non-parametric vs paired), multiple-testing adjustment, and rendering of negative results. Use when a boxplot/violin/raincloud needs in-figure statistical comparisons between groups.
日本語の概要は準備中です。原文の説明を表示しています。
Reconcile gene trees against a species tree under probabilistic models of duplication, transfer, and loss (DTL) using ALE (Szöllősi 2013 amalgamated likelihood), GeneRax (Morel 2020 ML reconciliation), AleRax (Morel 2024 co-estimation), Whale.jl (Bayesian DL+WGD), RANGER-DTL 2 parsimony, NOTUNG, ecceTERA, and Treerecs. Use when inferring ancestral gene-family content, distinguishing duplication from horizontal transfer from differential loss, rooting deep species trees from gene-content signals (STRIDE / Williams 2017 ALE-rooting), counting DTL events per branch, refining noisy gene trees against a species tree, modeling WGD events jointly with DTL, or producing publication-grade gene-family histories for phylogenomic / comparative analyses.
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Detects differential alternative splicing between conditions using rMATS-turbo (binomial LRT on junction counts), leafcutter (Dirichlet-multinomial GLM on intron clusters), MAJIQ V3 deltapsi/HET (Bayesian posterior on LSVs), SUPPA2 (empirical-null on TPM-derived PSI), or Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage). Reports FDR-corrected significance and delta PSI effect sizes. Tools differ in statistical model, annotation dependence, calibration regime, and replicate-count requirements. Use when comparing splicing patterns between treatment groups, tissues, or disease states.
日本語の概要は準備中です。原文の説明を表示しています。