1.2万 件 ・ 関連度順
概要と使いどころ
Facilitate a structured conversation to define DDD guardrails for domain design within a repository. Produces a formal ddd-principles.md document that the domain-driven-design atom will use as its override. Use when setting up domain design principles, defining aggregate rules, or when the user says 'setup DDD', 'define domain rules', 'DDD principles', or 'help me define my domain patterns'.
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user wants to design, rewrite, refine, or vary emotional acting prompts for live-action AI video characters. Translate abstract emotions, dialogue, subtext, and scene context into concise, observable, temporally ordered micro-performance directions. Preserve the user's existing character, scene, camera, and dialogue requirements unless they explicitly ask to change them. Do not use for general story writing, shot design, action choreography, or visual asset design when emotional performance is not the main task.
日本語の概要は準備中です。原文の説明を表示しています。
Designs covalent inhibitors and warheads targeting cysteine (most common, 98% of covalent drugs), lysine, serine, threonine, tyrosine, and aspartate residues, with explicit handling of warhead reactivity (acrylamide, chloroacetamide, vinyl sulfone, sulfonyl fluoride, fluorosulfate, aldehyde, boronate, nitrile), reversibility (kinact/Ki, t_residence), glutathione (GSH) stability, intrinsic reactivity assays, and covalent docking (DOCKovalent, GOLD, HCovDock). Use when designing covalent inhibitors for targeted covalent inhibition (TCI), KRAS G12C-style approaches, or rationalizing covalent SAR.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end CRISPR experiment design from target selection to delivery-ready constructs. Covers guide RNA design, off-target assessment, and specialized editing strategies including knockouts, base editing, and HDR knockins. Use when designing complete CRISPR editing experiments for gene knockout, correction, or tagging.
日本語の概要は準備中です。原文の説明を表示しています。
Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction. Select optimal positions for C-to-T or A-to-G conversions without double-strand breaks. Use when designing base editor experiments for precise nucleotide changes.
日本語の概要は準備中です。原文の説明を表示しています。
Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.
日本語の概要は準備中です。原文の説明を表示しています。
AlphaFold2 / AlphaFold-Multimer structure prediction for validation and confidence scoring. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm2-sequence-scoring. For QC thresholds, use protein-design-qc.
日本語の概要は準備中です。原文の説明を表示しています。
Chai-1 structure prediction for protein complexes and design validation. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For ESM-based analysis, use esm2-sequence-scoring.
日本語の概要は準備中です。原文の説明を表示しています。
Fetch and analyze protein structures from RCSB PDB. Use this skill when: (1) Need to download a structure by PDB ID, (2) Search for similar structures, (3) Prepare target for binder design, (4) Extract specific chains or domains, (5) Get structure metadata. For sequence lookup, use uniprot. For binder design workflow, use binder-design.
日本語の概要は準備中です。原文の説明を表示しています。
Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
日本語の概要は準備中です。原文の説明を表示しています。
Binder design tool selection and workflow routing guidance. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).
日本語の概要は準備中です。原文の説明を表示しています。
ESM2 protein language model for sequence scoring, embeddings, and plausibility checks. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai1-structure-prediction or boltz-structure-prediction. For QC thresholds, use protein-design-qc.
日本語の概要は準備中です。原文の説明を表示しています。
Create, implement, or review tailwind design system work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on tailwind design system.
日本語の概要は準備中です。原文の説明を表示しています。
Create, implement, or review penpot ui/ux design work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on penpot ui/ux design.
日本語の概要は準備中です。原文の説明を表示しています。
Apply experimental design in reproducible local data workflows with version-aware APIs, explicit assumptions, and validation. Use when the user chooses experimental design or its strengths fit the task.
日本語の概要は準備中です。原文の説明を表示しています。
Create, implement, or review design engineering craft work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on design engineering craft.
日本語の概要は準備中です。原文の説明を表示しています。
Plan, implement, or review api designer work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests api designer work.
日本語の概要は準備中です。原文の説明を表示しています。
Bulk-regenerate broken test selectors after a UI refactor or redesign. Detects drift between old and new DOM with an aria-snapshot diff, maps old locators to new equivalents using role-first + region scoping, validates against the new build, and produces a single PR with grouped per-file selector updates and per-change evidence. Assumes Playwright >= 1.50 (trace viewer DOM-snapshot panel, getByRole filtering, ariaSnapshot). Use when: "UI refactor broke tests," "redesign broke tests," "bulk update selectors," "regenerate selectors after refactor," "selector drift," "fix N broken tests after redesign." Not for: healing one flaky test at runtime — use test-reliability. Not for: writing a new test suite from scratch — use playwright-automation. Not for: re-recording tests after a framework switch (Selenium to Playwright) — use test-migration. Related: test-reliability, playwright-automation, test-migration, ci-cd-integration, visual-testing.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill when the user wants to author, design, scope, or refine an Agent Skill (a SKILL.md file). Trigger phrases include "build a new skill", "design an agent skill", "scope a SKILL.md", "how should I structure this skill", "write a skill for X", "my skill isn't working well", or any request to improve an existing SKILL.md. Walks the user through an empirical, test-first process — probe the agent for real failures, design only for genuine knowledge gaps, iterate against runnable examples, and verify across models.
日本語の概要は準備中です。原文の説明を表示しています。
Shared vocabulary for designing deep modules. Use when the user wants to design or improve a module's interface, find deepening opportunities, decide where a seam goes, make code more testable or AI-navigable, or when another skill needs the deep-module vocabulary.
日本語の概要は準備中です。原文の説明を表示しています。
Connect user journeys to screens, defining the UI structure and navigation paths during PRD v0.4 User Journeys. Triggers on requests to define screens, design screen flows, map UI structure, plan navigation, or when user asks "what screens do we need?", "define screens", "screen flow", "UI structure", "information architecture", "navigation design", "wireframe planning". Consumes UJ- (User Journey Mapping), FEA- (Feature Value Planning), BR- (constraints). Outputs SCR- entries for screens and DES- entries for design system elements. Feeds v0.5 Red Team Review.
日本語の概要は準備中です。原文の説明を表示しています。
Define implementation contracts (APIs and data models) that developers will build against during PRD v0.6 Architecture. Triggers on requests to define APIs, design database schema, create data models, or when user asks "define APIs", "data model", "database schema", "API contracts", "technical spec", "endpoint design", "schema design". Consumes ARC- (architecture), TECH- (Build items), UJ- (flows), SCR- (screens). Outputs API- entries for endpoints and DBT- entries for data models. Feeds v0.7 Build Execution.
日本語の概要は準備中です。原文の説明を表示しています。
Apply when integrating a new requirement into an existing design. Redesign as if the requirement had been a foundational assumption from day one, instead of bolting it on.
日本語の概要は準備中です。原文の説明を表示しています。
Non-animation creative direction for HyperFrames videos. Use for design spec (frame.md / design.md) handling, palettes, typography, beat planning, composition patterns, and brand / style decisions. For atomic motion patterns and scene blueprints, use `hyperframes-motion`.
日本語の概要は準備中です。原文の説明を表示しています。