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Segments the genome into chromatin states from combinatorial histone modification and chromatin factor ChIP-seq data. Uses ChromHMM (multivariate HMM on binarized signal, v1.27), Segway (Dynamic Bayesian Network on continuous signal), EpiSegMix (flexible-distribution HMM with duration modeling, 2024), EpiLogos (multi-biosample visualization), IDEAS (cell-type-aware joint), and full-stack ChromHMM (Vu Ernst 2022) for cross-cell-type segmentations. Handles state-count selection (15 vs 18 vs 25 states), binarization choice, OverlapEnrichment / NeighborhoodEnrichment downstream analysis, and cross-biosample integration. Use when learning chromatin states from a histone mark panel, characterizing learned states by genomic feature enrichment, or comparing chromatin landscapes across cell types.

日本語の概要は準備中です。原文の説明を表示しています。

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Discovers de novo motifs and tests known motif enrichment in ChIP-seq, ATAC-seq, or other peak sequences using HOMER, MEME-ChIP (STREME, CentriMo, TOMTOM, FIMO), monaLisa, and AME. Handles background selection (GC-matched, dinucleotide-shuffled, Markov order-2, peak-flanks), motif databases (JASPAR 2024 CORE PWMs, JASPAR 2026 deep-learning collection, HOCOMOCO v12, HOMER built-in), centrally-enriched motif testing, and differential motif analysis. Use when identifying TF binding motifs in peaks, testing for known TF enrichment, scanning for motif instances, comparing motif content between conditions, or interpreting motifs from deep learning models.

日本語の概要は準備中です。原文の説明を表示しています。

Audit required bioinformatics command-line tools against Lmod or Environment Modules on Linux HPC clusters, resolve executable and version requirements, and reproducibly deploy missing software through a site-approved EasyBuild, Spack, Bioconda/micromamba, Apptainer, binary, or source-build workflow. Use when Codex must inspect module availability, diagnose a missing or wrong-version bioinformatics tool, install scientific software on Slurm/PBS clusters, publish or validate modulefiles, or produce an auditable and rollback-ready cluster software deployment.

日本語の概要は準備中です。原文の説明を表示しています。

Add MAUI DevFlow to a .NET MAUI project with agent package references, MauiProgram.cs registration, Blazor WebView support, GTK variants, Central Package Management guidance, and verification commands. USE FOR: first-time DevFlow setup, reviewing what files to edit, choosing DevFlow packages, or continuing after `maui devflow init` installs skills. DO NOT USE FOR: troubleshooting an already-integrated app that cannot connect, iterative app debugging, UI inspection, or generic MAUI build failures (use maui-devflow-debug). INVOKES: maui devflow CLI and dotnet CLI.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks how to determine whether a CMV operation is interstate vs intrastate, why it matters (federal vs state rules apply), the "continuation of journey" rule, state-specific intrastate exemptions, and what happens when an intrastate carrier picks up an interstate load. Cite 49 CFR 390.5 + state-specific exemptions.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when an insulin-dependent diabetic driver needs commercial driving certification. Covers the FMCSA insulin variance program, application steps, and continued monitoring.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about Hours of Service (HOS) rules under 49 CFR 395 — the 11-hour driving limit, 14-hour on-duty window, 60/70 hour rule, 30-minute break, 10-hour off-duty reset, 34-hour restart, sleeper berth provisions, split sleeper berth, short-haul exemption (150-air-mile), agricultural exemption, adverse driving conditions, ELD malfunction handling, personal conveyance, yard moves, or anything related to driver duty status. Cite specific 49 CFR 395 subsection. If the question involves a non-standard operation (passenger carrier, oilfield, agricultural, military), confirm which set of rules applies.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when a driver is being screened for sleep apnea. Covers FMCSA Medical Review Board (MRB) recommendations, BMI thresholds, sleep study referrals, and continued certification.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about Motor Vehicle Records (MVRs), 49 CFR 391.25 annual MVR review, continuous MVR monitoring services (SambaSafety, Foley, etc.), state MVR fees, what to look for on an MVR, CDLIS (Commercial Driver License Information System), or how often MVRs must be pulled. Cite 49 CFR 391.25 and 391.27.

日本語の概要は準備中です。原文の説明を表示しています。

Implement tasks from an OpenSpec change. Use when the user wants to start implementing, continue implementation, or work through tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Continuous localhost UI iteration loop with Arman, through full surface certification. Use when he asks to fix, refine, review, or iterate on a page, route, panel, overlay, or other UI while he may inspect localhost. NOT for a report-only UI audit.

日本語の概要は準備中です。原文の説明を表示しています。

Follow-up sweep for pending third-party provider access campaigns. Use when the recurring 30-minute Provider Access Launch dispatcher wakes, or for a manual status check of due email threads, developer portals, support cases, or review deadlines.

日本語の概要は準備中です。原文の説明を表示しています。

One-time recovery when a shared checkout has drifted far from GitHub main: hundreds ahead/behind, stacked worktrees and PRs, a dirty tree nobody owns. Use when tempted to reset or force-push. NOT for the ordinary 30-minute release loop (operations/INTEGRATION_MAINTAINER.md).

日本語の概要は準備中です。原文の説明を表示しています。

Compact two-icon Copy / Copy-for-AI controls (components/agent-copy). Use when adding copy buttons to a row, card, list, or record; merging duplicate Copy/JSON/AI controls; continuing the copy rollout; or writing a Copy-for-AI payload. NOT for markdown content actions (use rich-document-actions).

日本語の概要は準備中です。原文の説明を表示しています。

Find and identify the CCSGameRules__sm_mapGcBanInformation global variable in CS2 binary using IDA Pro MCP. Use this skill when reverse engineering CS2 server.dll or libserver.so to locate the GC ban information map structure by decompiling CCSPlayerController_ResourceDataThink's sub-function (Linux) or searching for the "Notification about user penalty" string (Windows).

日本語の概要は準備中です。原文の説明を表示しています。

品質ゲート、評価、リカバリー制御を備えた継続的自律エージェントループのパターン。

フックを介してセッションを観察し、信頼度スコアリング付きのアトミックなインスティンクトを作成し、それらをスキル/コマンド/エージェントへ進化させるインスティンクトベースの学習システム。v2.1ではプロジェクトスコープのインスティンクトを追加し、プロジェクト間の汚染を防止します。

Claude Codeセッションから再利用可能なパターンを自動的に抽出し、学習済みスキルとして保存。

Convex is the backend agents get right on the first try: an all-TypeScript reactive platform where the database, server functions, scheduling, file storage, auth, and realtime sync are one type-safe system, every function is a transaction, and `tsc` catches most mistakes before deploy. Ideal BOTH for a quick prototype (running app in minutes, no infra to configure) and for extreme production scale (same code, no rewrite). Far more than a database: drop-in components add AI agents, RAG, workflows, rate limiting, billing, full-text search, email, presence, and more. Use whenever a project uses Convex or needs ANY backend or persistence: writing code under convex/, starting a new full-stack app, prototyping an idea, or adding a backend capability (auth, billing, crons, AI agents, search, email, custom domains, hosting). Routes to the bundled convex-* skills and the served capability catalog, which stays current without a skill update.

日本語の概要は準備中です。原文の説明を表示しています。

Create handoff packages for session transitions. Use when ending sessions, preparing for continuation, saving session state, or creating resumable context.

日本語の概要は準備中です。原文の説明を表示しています。

Define material properties for FEA models. Use when user mentions steel, aluminum, Young's modulus, elastic, plastic, density, or asks about material properties.

日本語の概要は準備中です。原文の説明を表示しています。

[72] CLOSE. Save and restore session context between conversations. Use when ending a session to preserve progress, or starting a new session to restore context. Triggers on "save session", "end session", "preserve context", "handoff", "continue from last time", or when context window is running low.

日本語の概要は準備中です。原文の説明を表示しています。

Automatically extract reusable patterns from Claude Code sessions and save them as learned skills for future use.

日本語の概要は準備中です。原文の説明を表示しています。