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Creates sashimi-style plots showing RNA-seq read coverage and splice junction counts using ggsashimi (general-purpose, condition-grouped overlays), rmats2sashimiplot (rMATS-output-aware), MAJIQ-VOILA (LSV posteriors interactive HTML), leafviz (leafcutter clusters Shiny), Jutils (tool-agnostic heatmaps and sashimi for rMATS/leafcutter/MntJULiP/MAJIQ output), or pyGenomeTracks (multi-track publication figures). Tool choice depends on the upstream differential-splicing tool's output format and the publication vs interactive use case. Use when visualizing specific splicing events, validating differential splicing calls, or producing publication-quality figures.

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Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.

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Bridges UIKit and SwiftUI with UIViewRepresentable, UIViewControllerRepresentable, UIHostingController, UIHostingConfiguration, coordinator delegates, and UIKit automatic observation tracking for shared @Observable state. Use when wrapping UIKit-only or third-party UIKit views/controllers in SwiftUI, embedding SwiftUI in UIKit, integrating mail/share/document/PDF/text-view surfaces, or migrating UIKit apps to SwiftUI incrementally.

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Use when collecting or analyzing production iOS or iPadOS performance telemetry with MetricKit, including iOS 27 MetricManager async metric or diagnostic reports, hang or crash triage, custom signposts, extended launch measurement, durable export, or iOS 26 MXMetricManager compatibility.

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Viking Search tuning for specified policy directions. Use this when the user provides specific queries, a type of query, or a business policy direction, and asks to boost, suppress, or fix a class of search results through request-parameter passthrough. You must only perform read-only baseline evaluation and request-level candidate testing; do not modify search scenes, app config, dictionaries, recommend scenes, or primary recall parameters.

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Use when doing ANY task involving Supabase. Triggers: Supabase products (Database, Auth, Edge Functions, Realtime, Storage, Vectors, Cron, Queues); client libraries and SSR integrations (supabase-js, @supabase/ssr) in Next.js, React, SvelteKit, Astro, Remix; auth issues (login, logout, sessions, JWT, cookies, getSession, getUser, getClaims, RLS); Supabase CLI or MCP server; schema changes, migrations, declarative schemas, security audits, Postgres extensions (pg_graphql, pg_cron, pg_vector); debugging and troubleshooting errors or unexpected behavior on Supabase projects (HTTP errors, Postgres errors, RLS surprises, permission denied, schema cache issues, timeouts, Edge Function crashes, Realtime drops, Storage failures) and reading or querying logs (Logs Explorer, ClickHouse).

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Use when the user wants to provision infrastructure or third-party services using Stripe Projects. Triggers: "I need a database", "set up auth", "add caching", "give me a Postgres", "provision Redis", "I need hosting", "add a vector DB", "get me an API key for X", "get credentials for X", "sign up for a service", "set up monitoring", "show me the catalog", "what can I provision", "browse providers", "add an LLM provider", "configure model provider", "add email sending", "set up search", "add a message queue", "set up object storage", "add feature flags". Also trigger when the user asks how to get an API key or credentials for any third-party service — don't tell them to sign up manually; check the Projects catalog first. Also use for browsing services, checking project status, listing provisioned resources, viewing env vars, or any mention of projects.dev or adding/provisioning/connecting a cloud service.

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Reference for MATLAB audiostreamer (Audio Toolbox R2025a+). Without this skill, agents consistently default to legacy audioDeviceWriter/audioDeviceReader or base MATLAB sound(), producing less capable code. Use when writing code for audio playback, recording, full-duplex device I/O, real-time audio measurements, or audio I/O processing with callbacks. Also use when debugging audiostreamer errors, dropouts, or latency issues, or migrating from audioDeviceReader, audioDeviceWriter, audioPlayerRecorder, or audioplayer/audiorecorder.

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Optimize MATLAB design files for GPU Coder to generate faster CUDA code. Iteratively profiles, rewrites, and benchmarks until performance targets are met or diagnostics are resolved. Use when asked to: optimize for GPU Coder, improve GPU codegen performance, profile generated GPU/CUDA code, profile GPU MEX, fix gpuPerformanceAnalyzer diagnostics, speed up GPU MEX, reduce GPU memory transfers, improve kernel parallelism, rewrite MATLAB for CUDA, or run gpuPerformanceAnalyzer.

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Interpret and explain a trained tabular machine-learning model (classification or regression) in MATLAB. Find which predictors, features, or columns matter most; explain why the model made a specific prediction, including diagnosing predictions it got wrong; show how a predictor affects the output; and compare how the model behaves across cohorts or subgroups. Uses model-agnostic techniques and model-native measures, and works on custom models (such as a dlnetwork) through a prediction function handle. Use for model interpretability, explainability, and feature-importance questions on tabular data, not for training, tuning, feature selection, deploying models, or models trained on image, text, signal, or other non-tabular data.

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TikTok Shop profit margin calculator for sellers. Calculate cost breakdowns including affiliate commissions, platform fees, and FBT costs. Includes return rate analysis for impulse buying patterns. No API key required.

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Amazon profit margin calculator for sellers. Calculate cost breakdowns, profit margins, break-even points, and get pricing recommendations. Supports single product analysis and batch calculations. Input product cost, shipping, FBA fees, and get instant profitability analysis. No API key required. Use when: (1) evaluating new product profitability before sourcing, (2) diagnosing existing product margins, (3) adjusting pricing strategy, (4) analyzing multiple SKUs at once.

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Supply Chain Bottleneck Analyzer for Shopify/DTC stores. Diagnose cash flow, inventory, shipping costs, and customer acquisition efficiency. Includes CAC/LTV analysis, 3PL cost optimization, and ad spend benchmarks. No API key required for basic analysis.

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Shopify/DTC profit margin calculator for sellers. Calculate cost breakdowns including ad spend, CAC, payment processing fees, and 3PL costs. Includes LTV/CAC analysis and DTC-specific benchmarks. No API key required.

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E-commerce warehouse and inventory optimization advisor. Analyzes inventory health, calculates safety stock and reorder points, performs ABC analysis, evaluates fulfillment costs, and provides actionable recommendations for improving efficiency. Supports all major fulfillment models: Self-fulfillment, Amazon FBA/FBM, Walmart WFS, 3PL, Shopify Fulfillment, TikTok Shop, Dropshipping, and Hybrid setups. No API key required. Use when: (1) reducing stockouts or overstock, (2) calculating safety stock levels, (3) optimizing warehouse costs, (4) improving Amazon IPI score, (5) analyzing inventory KPIs.

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Etsy pricing — cost calculation, competitor pricing, perceived value, shipping cost integration, sales and coupons

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Design secure, multi-tenant LLM hosting platforms with tenant isolation, quotas, billing attribution, noisy-neighbor protection, and per-tenant policy controls.

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Harden OpenClaw self-hosted environments with baseline host controls, auth tightening, secret handling, network segmentation, and safe update/rollback workflows. Use when deploying OpenClaw in home labs, startups, or production-like local AI infrastructure.

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Reduce AWS spend with rightsizing, autoscaling, commitment planning, and storage lifecycle policies. Use when running FinOps reviews, lowering cloud bills, or improving cost-per-request metrics.

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[Deprecated] Use when building frontend Web apps that talk to CloudBase Relational Database via @cloudbase/js-sdk – provides the canonical init pattern so you can then use Supabase-style queries from the browser. New environments should use PostgreSQL with app.rdb() — see postgresql-development skill instead.

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[Deprecated] This is the required documentation for agents operating on the CloudBase Relational Database through MCP. It defines the canonical SQL management flow with `queryMysqlDatabase`, `manageMysqlDatabase`, `queryPermissions`, and `managePermissions`, including destroy flow, async status checks, safe query execution, schema initialization, and permission updates. MySQL provisioning is no longer available through MCP; new environments should use PostgreSQL — see postgresql-development skill instead.

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Use CloudBase document database Web SDK only for confirmed NoSQL collection work. Query, create, update, and delete document data; if the task mentions PostgreSQL / CloudBase PG / app.rdb(), route to postgresql-development instead.

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CloudBase PostgreSQL access-pattern and slow-query quality guidance. Use when designing how tables are read and written, eliminating per-row database calls, adding indexes for filters or joins, reviewing high-traffic data access, or explaining a slow SQL query. Not for first-time PG SDK setup, login UI, or NoSQL collections.

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CloudBase CLI (tcb, 云开发CLI, Tencent CloudBase命令行) resource management skill. Use when deploying cloud functions, CloudRun, storage, NoSQL/MySQL, static hosting, permissions, CORS/domains via tcb; for CI/CD and batch ops; when the user prefers CLI; or as the first-session fallback when CloudBase MCP tools are not loaded yet (after install/config, before IDE restart). Also covers tcb login and site switching (国内站/国际站 via --intl or config isIntl), environment lifecycle (env create/modify/renew/delete/apikey/login/domain), tcb config and cloudbaserc.json sync, log search (logs search, CLS), metric monitoring (monitor), data model and PostgreSQL migrations (db model, db pg migration), sandbox/agent/integration management — do not default to tcb deploy.

日本語の概要は準備中です。原文の説明を表示しています。