「soc」の検索結果

Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.

日本語の概要は準備中です。原文の説明を表示しています。

This skill recommends that all patients with Cushing’s syndrome receive monitoring and adjunctive treatment for cortisol-dependent comorbidities including psychiatric disorders, diabetes, hypertension, hypokalemia, infections, dyslipidemia, osteoporosis, and poor physical fitness. Apply when managing any CS patient to address associated health issues; triggers include confirmed or suspected hypercortisolism, preoperative evaluation, postoperative follow‑up, or persistent hypercortisolism despite treatment.

日本語の概要は準備中です。原文の説明を表示しています。

Work up Malignancy-Associated Hypercalcemia (MAH) — distinguish humoral hypercalcemia of malignancy (HHM, PTHrP-driven), local osteolytic hypercalcemia, 1,25(OH)2D-mediated lymphoma hypercalcemia, ectopic PTH secretion, and multiple myeloma — and pick the right confirmatory tests and therapy direction. Trigger when a clinician asks "is this hypercalcemia from cancer", "PTHrP positive what now", "hypercalcemia in lung cancer / breast cancer / lymphoma / myeloma", "humoral hypercalcemia of malignancy", "MAH workup", or any hypercalcemia case with suppressed PTH and a known or suspected malignancy.

日本語の概要は準備中です。原文の説明を表示しています。

This skill recommends lifelong follow-up tests for cardiac myxoma and associated disease (testicular tumors, acromegaly, thyroid lesions) in patients with Carney complex. Use when managing a Cushing’s syndrome patient with a confirmed or suspected Carney complex diagnosis (e.g., spotty skin lentigines, cardiac myxoma, endocrine tumors).

日本語の概要は準備中です。原文の説明を表示しています。

This skill suggests follow-up tests for specific comorbidities associated with Cushing's syndrome in patients with adrenal adenoma when CT density is less than 10 Hounsfield units. Use when managing a post-adrenalectomy Cushing's syndrome patient with confirmed adrenal adenoma pathology and low-density imaging (<10 HU).

日本語の概要は準備中です。原文の説明を表示しています。

Determines whether a hypertensive patient should be screened for primary aldosteronism based on clinical features associated with higher PA prevalence. Triggered when a clinician asks 'Should I screen this hypertensive patient for PA?' or observes spontaneous hypokalemia, resistant hypertension, hypertension onset before age 40, adrenal tumor, young-onset stroke, or sleep apnea syndrome.

日本語の概要は準備中です。原文の説明を表示しています。

Recommends checking and managing vitamin D according to Endocrine Society guidelines to avoid hypocalcemia in patients receiving bisphosphonates or denosumab for hypercalcemia of malignancy. Use when a clinician notes risk factors for hypocalcemia (e.g., low 25‑OH vitamin D, renal insufficiency) and asks about baseline labs before antiresorptive start.

日本語の概要は準備中です。原文の説明を表示しています。

This skill suggests treatment with either a calcimimetic or an intravenous bisphosphonate/denosumab for hypercalcemia due to parathyroid carcinoma. Triggered when a clinician diagnoses parathyroid carcinoma-associated hypercalcemia of malignancy and inquires about initial medical management options.

日本語の概要は準備中です。原文の説明を表示しています。

The Endocrine Society recommends a standard-dose corticotropin (ACTH) stimulation test to confirm primary adrenal insufficiency when clinical suspicion arises from symptoms such as hypotension, hyponatremia, hyperkalemia, or unexplained fatigue. Dosing is weight/age based: 250 µg for adults and children ≥2 years, 15 µg/kg for infants, and 125 µg for children <2 years.

日本語の概要は準備中です。原文の説明を表示しています。

The Endocrine Society guideline recommends against routine hormonal monitoring of glucocorticoid replacement in primary adrenal insufficiency and advises adjusting therapy solely based on clinical response. Use when evaluating glucocorticoid dose adequacy, such as when patients report fatigue, weight loss, hypotension, or signs of Cushingoid over-replacement.

日本語の概要は準備中です。原文の説明を表示しています。

Guide a non-stigmatising pediatric obesity consultation using the 5As framework (Ask, Assess, Advise, Agree, Assist) and 4Ms assessment (Metabolic, Mechanical, Mental Health, Social Milieu), based on the CMAJ 2025 guideline. Trigger when a clinician asks how to approach a weight conversation with a child or family, how to use the 5As for obesity, how to assess a child with obesity, or how to conduct a non-judgmental obesity visit.

日本語の概要は準備中です。原文の説明を表示しています。

PM-mode brainstorm helper. Captures the requirement via Socratic dialogue before any entry phase (`/intake`, `/spec`, `/tdd`) drafts its artifact. Stage 0 skip-check, Stage 1 gap-analysis, Stage 2 probe-loop, Stage 3 confirm-and-persist. Output lives at `docs/brief/<slug>.md`. Never proposes solutions — Stage 2 dialogue discipline is structurally enforced via `discipline.mjs`.

日本語の概要は準備中です。原文の説明を表示しています。

Azure AI Voice Live SDK for JavaScript/TypeScript. Build real-time voice AI applications with bidirectional WebSocket communication.

日本語の概要は準備中です。原文の説明を表示しています。

Azure AI Voice Live SDK for .NET. Build real-time voice AI applications with bidirectional WebSocket communication.

日本語の概要は準備中です。原文の説明を表示しています。

Azure AI VoiceLive SDK for Java. Real-time bidirectional voice conversations with AI assistants using WebSocket.

日本語の概要は準備中です。原文の説明を表示しています。

Build real-time voice AI applications with bidirectional WebSocket communication.

日本語の概要は準備中です。原文の説明を表示しています。

Automated compliance checking against CIS, PCI-DSS, HIPAA, and SOC 2 benchmarks

日本語の概要は準備中です。原文の説明を表示しています。

Map Delphi classes to a relational database using TMS Aurelius ORM attributes. Use when the user asks to create entity classes, add Aurelius mapping to existing classes, fix or review mapping attributes, explain how a class is mapped, or work with associations, inheritance, automapping, nullable fields, blobs, or composite identifiers. Triggers on requests like "create Aurelius entities for...", "map this class to Aurelius", "add ORM mapping", "fix the mapping on this class", "how do I map a one-to-many in Aurelius".

日本語の概要は準備中です。原文の説明を表示しています。

Save, load, update, delete, merge, and navigate entity objects using TMS Aurelius ORM (TObjectManager). Use when the user asks how to persist or retrieve data with Aurelius, manage object lifetime, work with associations or collections at runtime, handle transactions, use cached updates, or control concurrency. Does NOT cover query DSL or criteria/projections (those are in a separate skill). Triggers on requests like "save an entity with Aurelius", "load a customer from the database", "add items to a collection", "how do I update an object", "flush changes", "delete a record with Aurelius", "merge a transient object", "how do transactions work in Aurelius", "batch updates Aurelius".

日本語の概要は準備中です。原文の説明を表示しています。

Find the first batch of foreign-trade prospect companies from public web, LinkedIn, and user-authorized data sources such as customs exports, trade show lists, association directories, CRM/Excel files, or historical customer data, then output a conservative, structured candidate list ready for lead screening.

日本語の概要は準備中です。原文の説明を表示しています。

Add Wasp's built-in features to your app: auth, email, jobs, and more. These are full-stack, batteries-included features that Wasp handles for you. Use when the user wants to add meta tags, authentication (email, social auth providers), email sending, database setup, styling (tailwind, shadcn), or other Wasp-powered functionality.

日本語の概要は準備中です。原文の説明を表示しています。

Create professional visual assets for GitHub repositories — architecture diagrams, social cards, and README banners.

日本語の概要は準備中です。原文の説明を表示しています。

Run 150+ AI applications in the cloud via the inference.sh platform. Triggers on "generate image with FLUX", "create video", "use Veo/Seedance", "run inference.sh", "infsh CLI", "single key for image+video+LLM". One API key covers image generation (FLUX, Reve, Seedream, Grok, Gemini), video (Veo, Wan, Seedance, OmniHuman, HunyuanVideo), LLMs (Claude, Gemini, Kimi, GLM-4), search (Tavily, Exa), 3D (Rodin), social (Twitter/X), and audio (TTS, voice cloning).

日本語の概要は準備中です。原文の説明を表示しています。

PIL + ffmpeg slideshow videos: product reviews, promos, TikTok/Reels/Shorts.

日本語の概要は準備中です。原文の説明を表示しています。