2万 件 ・ 関連度順
BullMQ expert for Redis-backed job queues, background processing, and reliable async execution in Node.js/TypeScript applications. Use when: bullmq, bull queue, redis queue, background job, job queue.
日本語の概要は準備中です。原文の説明を表示しています。
Biopython is a comprehensive set of freely available Python tools for biological computation. It provides functionality for sequence manipulation, file I/O, database access, structural bioinformatics, phylogenetics, and many other bioinformatics tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Expert backend architect specializing in scalable API design, microservices architecture, and distributed systems.
日本語の概要は準備中です。原文の説明を表示しています。
Build robust, production-grade backtesting systems that avoid common pitfalls and produce reliable strategy performance estimates.
日本語の概要は準備中です。原文の説明を表示しています。
Connect to Azure Database for PostgreSQL Flexible Server from Node.js/TypeScript using the pg (node-postgres) package.
日本語の概要は準備中です。原文の説明を表示しています。
Azure Queue Storage SDK for Python. Use for reliable message queuing, task distribution, and asynchronous processing.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze text and images for harmful content with customizable blocklists.
日本語の概要は準備中です。原文の説明を表示しています。
Audit and rewrite content to remove 21 categories of AI writing patterns with a 43-entry replacement table
日本語の概要は準備中です。原文の説明を表示しています。
Enables ultra-granular, line-by-line code analysis to build deep architectural context before vulnerability or bug finding.
日本語の概要は準備中です。原文の説明を表示しています。
Extract text, tables, and structured data from documents using prebuilt and custom models.
日本語の概要は準備中です。原文の説明を表示しています。
Azure AI Document Intelligence SDK for .NET. Extract text, tables, and structured data from documents using prebuilt and custom models.
日本語の概要は準備中です。原文の説明を表示しています。
Build secure, scalable authentication and authorization systems using industry-standard patterns and modern best practices.
日本語の概要は準備中です。原文の説明を表示しています。
You are an API mocking expert specializing in realistic mock services for development, testing, and demos. Design mocks that simulate real API behavior and enable parallel development.
日本語の概要は準備中です。原文の説明を表示しています。
Design, audit, and improve analytics tracking systems that produce reliable, decision-ready data.
日本語の概要は準備中です。原文の説明を表示しています。
I build AI systems that can act autonomously while remaining controllable. I understand that agents fail in unexpected ways - I design for graceful degradation and clear failure modes. I balance autonomy with oversight, knowing when an agent should ask for help vs proceed independently.
日本語の概要は準備中です。原文の説明を表示しています。
You bring the third dimension to the web. You know when 3D enhances and when it's just showing off. You balance visual impact with performance. You make 3D accessible to users who've never touched a 3D app. You create moments of wonder without sacrificing usability.
日本語の概要は準備中です。原文の説明を表示しています。
You know AI wrappers get a bad rap, but the good ones solve real problems. You build products where AI is the engine, not the gimmick. You understand prompt engineering is product development. You balance costs with user experience. You create AI products people actually pay for and use daily.
日本語の概要は準備中です。原文の説明を表示しています。
A hybrid memory system that provides persistent, searchable knowledge management for AI agents (Architecture, Patterns, Decisions).
日本語の概要は準備中です。原文の説明を表示しています。
Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.
日本語の概要は準備中です。原文の説明を表示しています。
Loads, converts, and manipulates Hi-C contact matrices in cooler format (.cool/.mcool/.scool) and Juicer .hic, using cooler (Python + CLI), hic2cool, and hictk. Covers the single-resolution mcool URI (file.mcool::/resolutions/<bp>), the load-bearing divisive-vs-multiplicative weight-naming rule (KR/VC/VC_SQRT auto-divisive vs cooler's multiplicative weight), what survives .hic<->.cool conversion (FRAG matrices and norm vectors do not), raw-vs-balanced coarsening, the .pairs upper-triangle/chromsize-order contract, and chrom-naming/bin-table provenance. Use when loading a cooler, converting .hic to .mcool, selecting a resolution, building a cooler from pairs or a matrix, coarsening/zoomifying, importing Juicer norm vectors, or debugging all-NaN balanced matrices and chr1-vs-1 empty fetches.
日本語の概要は準備中です。原文の説明を表示しています。
Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/blacklist masking before balancing, multiplicative cooler weights vs divisive juicer weights, and the resolution-vs-depth budget. Use when balancing a .cool/.mcool, computing expected or P(s), making O/E matrices for compartments/loops, deciding ICE vs KR vs SCALE, choosing a resolution for a given depth, or troubleshooting NaN/all-NaN balanced matrices; route cross-sample comparison to hic-differential.
日本語の概要は準備中です。原文の説明を表示しています。
Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer completeness), and correctness (reference-free Merqury QV, Inspector/CRAQ structural errors, asmgene false-duplication/collapse). Covers why N50 is the most-gamed metric, why QV measured on the polishing reads is circular, distinguishing uncollapsed haplotigs from real WGD, and the EBP/VGP 6.C.Q40 standard. Use when judging whether an assembly is good enough to annotate or publish, comparing assemblers, diagnosing a fragmented or duplicated assembly, or assessing a phased diploid assembly.
日本語の概要は準備中です。原文の説明を表示しています。
Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
日本語の概要は準備中です。原文の説明を表示しています。
Assembles a genome de novo from Illumina short reads with SPAdes (isolate/careful/sc/meta/plasmid/rna modes), MEGAHIT (low-memory, huge datasets), Unicycler (bacterial finishing/hybrid), MaSuRCA (large hybrid), ABySS (Bloom-filter), and Platanus (heterozygous diploids), using multi-k de Bruijn graphs. Covers the repeat-resolution limit, why N50 plateaus at the genome not the depth, GenomeScope2 k-mer profiling first, the heterozygosity/haplotig trap, error-correction erasing rare alleles, GC dropout, and NG50/auN/BUSCO reporting. Use when assembling a bacterial isolate, fungal, small-eukaryotic, single-cell, or metagenome genome from Illumina reads, or when deciding whether short reads can even produce the assembly being asked for.
日本語の概要は準備中です。原文の説明を表示しています。