「amo」の検索結果

Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger, MR-PRESSO, MR-RAPS, CAUSE, LHC-MR, LCV, MR-Clust, MR-Mix, and contamination-mixture methods. Use when validating an MR causal claim, running the STROBE-MR sensitivity battery, suspecting a shared heritable confounder, working under weak-instrument or polygenic-exposure regimes, or reconciling discordant estimates across robust methods.

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Creates Dataverse tables, columns, and relationships for a Power Pages site based on a data model proposal. Use when the user wants to set up the data model, create database tables, or build the Dataverse schema for their site.

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Use when the user wants to design or redesign the Dataverse schema and connector plan for an existing mobile app, or has an ER diagram (image, Mermaid, or text) to apply. Skip when the user is creating a brand-new app — /create-mobile-app handles the data model inline.

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Use when animating characters or scenes in Godot 4.7: AnimationPlayer clips and RESET, AnimationTree state machines and blend spaces built in code, Mixamo or glTF import, loop settings, BoneMap retargeting and shared animation libraries, root motion, foot sliding, foot IK with TwoBoneIK3D or custom SkeletonModifier3D, tweens, SpringArm3D cameras, cutscenes; or when a character T-poses, slides, floats, freezes mid-blend or a transition never fires.

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Use when a Unity 6.3 task involves character animation or cameras: Mixamo or mocap humanoid import and retargeting, Animator Controllers, blend trees, layers and avatar masks, root motion, foot sliding, IK and Animation Rigging, Playables, Timeline cutscenes, custom tracks and markers, Cinemachine 3 cameras, camera jitter, flipping blends or cameras hitting walls; or when clips import with no animation, a character T-poses, an idle drifts, feet slide or the head misses its aim target.

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Generate cinematic film-style video prompts for Seedance 2.0 on Higgsfield. Use whenever the user wants cinematic, film-like, movie-quality, Hollywood-style, dramatic, or professional film-quality AI video. Triggers on: cinematic, film look, movie scene, dramatic lighting, depth of field, lens flare, anamorphic, letterbox, noir, epic, Steadicam, dolly, crane shot, or any cinematic video generation request. Always use this skill even if the user doesn't explicitly say "cinematic" but describes a film-like aesthetic.

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Molecular data processing, featurization, and cheminformatics workflows

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Build and deploy full-stack web and mobile apps with AWS Amplify Gen2 (TypeScript code-first). Covers auth (Cognito), data (AppSync/DynamoDB including schema modeling, enum types, relationships, authorization rules), storage (S3), functions, APIs, and AI (Amplify AI Kit with Bedrock). Supports React, Next.js, Vue, Angular, React Native, Flutter, Swift, and Android. Always use this skill for Amplify Gen2 topics — even for questions you think you know — it contains validated, version-specific patterns that prevent common mistakes. TRIGGER when: user mentions Amplify Gen2; project has amplify/ directory or amplify_outputs; code imports @aws-amplify packages; user asks about defineBackend, defineAuth, defineData, defineStorage, or npx ampx. SKIP: Amplify Gen1 (amplify CLI v6), standalone SAM/CDK without Amplify (use aws-serverless), direct Bedrock without Amplify AI Kit (use bedrock).

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Database design with schema analysis, index optimization, and migration generation for PostgreSQL, MySQL, MongoDB, and DynamoDB. Use when designing schemas, optimizing queries, planning migrations, or analyzing database performance.

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Design AWS serverless architectures for startups with IaC. Use when designing serverless architecture, writing CloudFormation, optimizing AWS costs, setting up CI/CD, or migrating to AWS across Lambda, API Gateway, and DynamoDB.

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When the user wants multiple expert perspectives on a marketing question — a simulated board of advisors staffed by legendary marketers (Seth Godin, David Ogilvy, Eugene Schwartz, April Dunford, Rory Sutherland, Alex Hormozi, Byron Sharp, and more). Also use when the user mentions 'marketing council,' 'board of advisors,' 'advisory board,' 'what would Seth Godin say,' 'what would Ogilvy think,' 'channel Hormozi,' 'get multiple perspectives,' 'debate this,' 'have the council review,' 'marketing mentors,' or asks how a famous marketer would approach their problem. The council gives each advisor's take through their documented frameworks, surfaces where they disagree, and synthesizes a recommendation. For executing the winning direction, hand off to positioning, offers, copywriting, ads, or the relevant skill.

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When you want multiple expert perspectives on a founder/operator question — a simulated board of advisors (Jason Fried, Elon Musk, Jeff Bezos, Jensen Huang, Bob Iger, Paul Graham, Naval Ravikant, Sara Blakely). Bring a real decision — "should I raise prices?", "hire my first employee?", "raise or bootstrap?", "kill this project?" — and the council weighs in through documented frameworks, surfaces disagreements, and synthesizes a recommendation. Also use for 'maker council,' 'board of advisors,' 'what would Bezos do,' 'what would Jason Fried say,' 'channel Naval,' 'ask the council,' or how a famous founder would approach a problem. Optional live-research pass via deep-research / watch-video / last30days. Marketing questions go to marketing-skills' marketing-council. Archives to ~/.config/makerskills/maker-council/archive/. To commit to a direction, hand off to decide.

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Epialleles are specific DNA methylation patterns that are mitotically and/or meiotically inherited. This package calls and reports cytosine methylation as well as frequencies of hypermethylated epialleles at the level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map (BAM) files as an input. Among other things, this package can also extract and visualise methylation patterns and assess allele specificity of methylation.

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This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enric

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Use when the user asks about visual styles, aesthetics, color grades, film looks, or how to set the tone and atmosphere of a Higgsfield generation.

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Weekdays, conditional browser lane. Selects from the ticket ledger hardest first, meaning by severity and then by age within severity, and writes each customer a reply into a dated queue file the member reads, edits, and sends by hand. Where the right answer is a refund, a credit, a plan change, or a cancellation, it names the remedy, the exact amount, and the exact screen, and leaves the granting to the member. It sends only where you released the channel, never posts, never resolves a ticket, spends only where you released it, and never touches a credential.

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Lambda best practices, S3 event patterns, SQS/SNS fanout, and DynamoDB access patterns for serverless AWS architectures.

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Document database implementation for flexible schema applications. Use when building content management, user profiles, catalogs, or event logging. Covers MongoDB (primary), DynamoDB, Firestore, schema design patterns, indexing strategies, and aggregation pipelines.

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This skill should be used when working with Vercel AI SDK, AI Gateway, streamText, generateText, generateObject, streamObject, tool calling, or AI SDK providers. Also relevant for "ai-sdk", "@ai-sdk/*" packages, or questions about AI SDK patterns, configuration, and best practices.

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Use when you need to review, improve, or refactor Java code for generics quality — including avoiding raw types, applying the PECS (Producer Extends Consumer Super) principle for wildcards, using bounded type parameters, designing effective generic methods, leveraging the diamond operator, understanding type erasure implications, handling generic inheritance correctly, preventing heap pollution with @SafeVarargs, and integrating generics with modern Java features like Records, sealed types, and pattern matching. This should trigger for requests such as Improve the code with Generics; Apply Generics; Refactor the code with Generics; Improve generic type safety in Java APIs; Fix raw types and unchecked casts in Java code. Part of Plinth Toolkit

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Cross-engine decision rubric for self-hosting or recommending an LLM serving stack. Picks among vLLM, SGLang, TensorRT-LLM, TGI, llama.cpp, Ollama, and MLX as a function of (hardware × workload × constraint), not "which is fastest". Activates whenever a coder-agent must choose, defend, or migrate a serving runtime.

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ENHANCE overlay on [[dspy]] — the upfront rubric for choosing a reasoning SHAPE (Predict / ChainOfThought / ReAct / ProgramOfThought) BEFORE you write a prompt or pick an optimizer. The local `dspy` skill lists the modules but never surfaces the *selection criterion*: reasoning shape is chosen by task structure, not by reflexively defaulting to CoT. Activate every time a new LM-calling node/step is added to a pipeline. Do NOT activate for one-shot prompts, optimizer/teleprompter choice (that is the dspy SOP's job), or non-LM control flow. Search keywords: chain of thought vs ReAct, when to use CoT, reasoning type, ReAct vs CoT vs PoT, which dspy module, predict vs chain of thought.

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Organize, categorize, track, and manage invoices systematically with automated extraction of invoice data, payment tracking, and financial organization. Use when processing invoice uploads, extracting invoice details (date, amount, vendor), categorizing expenses, tracking payment status, organizing receipts, generating financial reports, or building accounting and bookkeeping systems.

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Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

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