180 件 ・ 関連度順
概要と使いどころ
Analyze Chronote product adoption with PostHog and Langfuse, including active users, meetings, feature usage, AI telemetry, and privacy-safe resolution of active Discord guild IDs to live server names.
日本語の概要は準備中です。原文の説明を表示しています。
Call protein-RNA binding sites from CLIP-seq BAM with CLIPper, PureCLIP, Skipper, Piranha, omniCLIP, CTK, CLAM, or Paraclu. Use when choosing between coverage-based, HMM-based, beta-binomial window-based, and crosslink-site-based peak callers; applying ENCODE eCLIP thresholds (log2 IP/SMInput >= 3, -log10 p >= 3); deciding when SMInput is mandatory; or reconciling peak-set discordance between callers for the same RBP.
日本語の概要は準備中です。原文の説明を表示しています。
Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
日本語の概要は準備中です。原文の説明を表示しています。
Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger, MR-PRESSO, MR-RAPS, CAUSE, LHC-MR, LCV, MR-Clust, MR-Mix, and contamination-mixture methods. Use when validating an MR causal claim, running the STROBE-MR sensitivity battery, suspecting a shared heritable confounder, working under weak-instrument or polygenic-exposure regimes, or reconciling discordant estimates across robust methods.
日本語の概要は準備中です。原文の説明を表示しています。
Call protein-RNA binding sites from CLIP-seq BAM with CLIPper, PureCLIP, Skipper, Piranha, omniCLIP, CTK, CLAM, or Paraclu. Use when choosing between coverage-based, HMM-based, beta-binomial window-based, and crosslink-site-based peak callers; applying ENCODE eCLIP thresholds (log2 IP/SMInput >= 3, -log10 p >= 3); deciding when SMInput is mandatory; or reconciling peak-set discordance between callers for the same RBP.
日本語の概要は準備中です。原文の説明を表示しています。
Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger, MR-PRESSO, MR-RAPS, CAUSE, LHC-MR, LCV, MR-Clust, MR-Mix, and contamination-mixture methods. Use when validating an MR causal claim, running the STROBE-MR sensitivity battery, suspecting a shared heritable confounder, working under weak-instrument or polygenic-exposure regimes, or reconciling discordant estimates across robust methods.
日本語の概要は準備中です。原文の説明を表示しています。
Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
日本語の概要は準備中です。原文の説明を表示しています。
Tracks competitors weekly across 6 signals: pricing page diffs, homepage positioning changes, blog/RSS posts, job postings (hiring as strategy signal), GitHub star velocity and releases, and daily critical-change alerts for pricing or funding keywords. Delivers a structured digest to Slack, Telegram, WhatsApp, or Discord every Monday. Fires same-day alerts for critical changes. Use when asked to "add competitor", "track competitor", "competitor digest", "what changed at [company]", "competitor report", "monitor [company]", "who is [company] hiring", "did [company] change pricing".
日本語の概要は準備中です。原文の説明を表示しています。
Proactive monitoring of Aave V3 borrow positions with liquidation alerts. Queries user collateral, debt, and health factor across chains (Ethereum, Polygon, Arbitrum, etc.). Sends urgent alerts to Telegram/Discord/Slack when health factor drops below configurable thresholds (critical at 1.05, warning at 1.2). Use when you need continuous monitoring of Aave positions, want alerts before liquidation risk occurs, or need periodic summaries of your borrowing health.
日本語の概要は準備中です。原文の説明を表示しています。
Complete community building, engagement, and monetization system. From zero to thriving community — launch strategy, member engagement loops, content programming, moderation frameworks, growth tactics, monetization models, and health metrics. Works for Discord, Slack, Telegram, Circle, forums, or any platform.
日本語の概要は準備中です。原文の説明を表示しています。
Architects the encryption, codec/transport, and premium-feature layer of a group video-calling product, on top of an already-chosen SFU topology. Covers E2EE patterns (Zoom leader-fan-out, Signal pairwise-fan-out, MLS/TreeKEM as in Discord's DAVE, Telegram's ledger consensus), the SFrame (RFC 9605) + WebRTC Insertable Streams mechanism letting an SFU relay encrypted frames it can't read, codec/transport choice (AV1/VP9 SVC vs. simulcast, Opus, congestion control, Media-over-QUIC, WHIP/WHEP), and which "premium" features (virtual backgrounds, live captions, recording, breakout rooms, spatial audio) survive E2EE vs. structurally can't. Use when adding E2EE to an SFU-based call, choosing a 2026 codec/SVC strategy, or deciding which features to disable under E2EE mode. NOT for call topology/platform choice (see webrtc-adhoc-video-chat, which this composes with). NOT for one-way broadcast (see managed-video-streaming-pipeline). NOT for the DM/group-chat text backend (see realtime-messaging-backend-architecture).
日本語の概要は準備中です。原文の説明を表示しています。
Tiered web access router. TIER 1 insane-search: headless extraction plus WAF bypass via curl_cffi, yt-dlp, Jina Reader, public APIs, Playwright fallback for blocked/403/Cloudflare pages, articles, YouTube subtitles. TIER 1.5 agent-reach: platform-native readers for Chinese/social platforms: Xiaohongshu, Douyin, Weibo, Bilibili, V2EX, WeChat, plus Twitter/Reddit/LinkedIn/GitHub. TIER 2 aside-browser FIRST (user's real logged-in browser: aside exec agent, aside repl Playwright), then CloakBrowser + agent-browser as the stealth fallback: source-patched stealth Chromium (CloakBrowser) driven over CDP by the agent-browser CLI for clicks, forms, screenshots, video, cookie login, QA/dogfood, Electron apps. Triggers: browse, stealth browser, CloakBrowser, agent-browser, cloak launch, bypass bot detection, blocked site, scrape, fill form, screenshot, import cookies, play youtube, podcast transcript. NOT for simple searches (web-search), fetches (webfetch), or messaging/workspace platforms — Slack/Discord/Notion/Gmail have Tier-1 CLIs in external-communication; come here only as its fallback.
日本語の概要は準備中です。原文の説明を表示しています。