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概要と使いどころ
Read/write SAM/BAM/CRAM, VCF/BCF, FASTA/FASTQ. Region queries, pileup, variant filtering, read groups. Python htslib wrapper exposing samtools/bcftools CLI. Use STAR/BWA for alignment; GATK/DeepVariant for variant calling.
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Fast short-read DNA aligner for WGS/WES/ChIP-seq. 2× faster BWA-MEM successor; outputs SAM/BAM with read group headers for GATK. Primary plus supplementary records for chimeric reads. Use STAR for RNA-seq splice-aware alignment; Bowtie2 is a comparable alternative.
日本語の概要は準備中です。原文の説明を表示しています。
Biopython sequence analysis: parse FASTA/FASTQ/GenBank/GFF (SeqIO), NCBI Entrez (esearch/efetch/elink), remote/local BLAST, pairwise/MSA alignment (PairwiseAligner, MUSCLE/ClustalW), phylogenetic trees (Phylo). Use for gene family studies, phylogenomics, comparative genomics, NCBI pipelines. For PCR/restriction/cloning use biopython-molecular-biology; for SAM/BAM use pysam.
日本語の概要は準備中です。原文の説明を表示しています。
Python library for biology: sequence manipulation (DNA/RNA/protein), pairwise/multiple alignment, phylogenetic trees (NJ, UPGMA), diversity (Shannon, Faith PD, Bray-Curtis, UniFrac), ordination (PCoA, CCA, RDA), stats (PERMANOVA, ANOSIM, Mantel), file I/O (FASTA, FASTQ, Newick, BIOM). Use for microbiome, community ecology, or phylogenetics.
日本語の概要は準備中です。原文の説明を表示しています。
Patterns and best practices for integrating ROS2 systems with web technologies including REST APIs, WebSocket bridges, and browser-based robot interfaces. Use this skill when building web dashboards for robots, streaming camera feeds to browsers, exposing ROS2 services as REST endpoints, or implementing bidirectional WebSocket communication between web UIs and ROS2 nodes. Trigger whenever the user mentions rosbridge, rosbridge_suite, roslibjs, FastAPI with ROS2, Flask with rclpy, WebSocket for robot telemetry, MJPEG streaming, WebRTC for robots, REST API wrapping ROS2 services, web-based robot control, browser robot interface, robot dashboard, CORS configuration for robots, or any web-to-ROS2 bridge pattern. Also trigger for authentication on robot web interfaces, rate limiting sensor streams, video streaming from robot cameras to browsers, or running async web frameworks alongside the ROS2 executor. Covers rosbridge_suite, FastAPI, Flask, WebSocket, and WebRTC approaches.
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Operate FastReID setup, configuration, datasets, model/inference APIs, training/evaluation workflows, deployment/export paths, and extension projects for person and vehicle re-identification.
日本語の概要は準備中です。原文の説明を表示しています。
Guides TensorFlow Fast Style Transfer training, image stylization, and video stylization workflows from checkpoints, VGG/COCO assets, and script-oriented CLIs.
日本語の概要は準備中です。原文の説明を表示しています。
Route fastdup workflows for visual dataset curation, annotation-driven analysis, embeddings and search, and video or exchange plumbing.
日本語の概要は準備中です。原文の説明を表示しています。
Use the faster-whisper package for CTranslate2-backed Whisper transcription, model selection, CPU/CUDA setup, audio utilities, VAD, timestamps, and conversion guidance.
日本語の概要は準備中です。原文の説明を表示しています。
Use fastMRI for MRI reconstruction data loading, MRI operators, reconstruction models, Lightning training, evaluation, and submission preparation.
日本語の概要は準備中です。原文の説明を表示しています。
Guides FastVideo video, image, and audio generation, config-first inference, serving, training, distillation, evaluation, and performance workflows.
日本語の概要は準備中です。原文の説明を表示しています。
Fix intermittent 500 errors with "Failed to store" in Fastly KV Store during concurrent writes. Use when: (1) Batch operations fail with ~10-20% error rate, (2) Error contains "Failed to store list" or similar KV write failures, (3) Multiple requests updating the same KV key simultaneously, (4) Read-modify-write pattern without locking. The fix is adding a retry loop that re-reads before each write attempt.
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Fix .well-known files (apple-app-site-association, assetlinks.json) being served as HTML by the @fastly/compute-js-static-publish SPA fallback instead of JSON. Use when: (1) iOS Universal Links or Android App Links are broken because the verification files return text/html instead of application/json, (2) PublisherServer with spaFile config intercepts /.well-known/ paths and returns index.html (200, text/html) instead of 404 for missing files, (3) apple-app-site-association (no file extension) gets wrong content type even when correctly stored in KV. Covers both apex domain and subdomain handler patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Automatically migrate Python web applications between frameworks (Flask → FastAPI, Django → FastAPI). Use when you need to migrate an existing web application to a modern framework while preserving functionality. The skill analyzes the codebase, updates routes, handlers, configuration, dependency injection patterns, and tests. Creates git commits for each migration phase and generates a comprehensive summary of all changes. Supports automatic dependency updates, code transformations, and test adaptations.
日本語の概要は準備中です。原文の説明を表示しています。
Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end DNA sequencing workflow from FASTQ files to variant calls. Covers QC, alignment with BWA, BAM processing, and variant calling with bcftools or GATK HaplotypeCaller. Use when calling variants from raw sequencing reads.
日本語の概要は準備中です。原文の説明を表示しています。
Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
日本語の概要は準備中です。原文の説明を表示しています。
Reconstruct ancestral states at internal phylogenetic nodes for sequences (PAML codeml, IQ-TREE --ancestral, GRASP, FastML), discrete traits (corHMM hidden-rate Markov, ape::ace, phytools::make.simmap stochastic mapping, BayesTraits), and continuous traits (phytools::fastAnc, geiger Brownian/OU, RPANDA). Use when designing constructs for ancestral protein resurrection, tracing trait evolution along a tree, performing stochastic character mapping, testing models of trait evolution (BM vs OU vs EB), inferring ancestral genome content via Dollo or DTL reconciliation, or quantifying ancestral-state uncertainty for downstream comparative analyses.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end ATAC-seq workflow from FASTQ files to differential accessibility and TF footprinting. Covers alignment, peak calling with MACS3, QC metrics, and optional TOBIAS footprinting. Use when running end-to-end ATAC-seq analysis from FASTQ to differential accessibility.
日本語の概要は準備中です。原文の説明を表示しています。
Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequences. Use when FastQC shows adapter contamination or before alignment of short reads.
日本語の概要は準備中です。原文の説明を表示しています。
Automated sequencing quality control and advanced visualization wrapping FastQC, MultiQC, and custom chart generation. Exposes an MCP stdio server for live AI integration alongside a ClawBio CLI runner.
日本語の概要は準備中です。原文の説明を表示しています。
60-Second Property Snapshot — quick assessment without subagents for fast property evaluation with signal, key factors, and CTA for full analysis
日本語の概要は準備中です。原文の説明を表示しています。
Expert in launching small, focused SaaS products fast - the indie hacker approach to building profitable software. Covers idea validation, MVP development, pricing, launch strategies, and growing to sustainable revenue. Ship in weeks, not months. Use when "micro saas, indie hacker, small saas, side project, saas mvp, ship fast, " mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
CI/CD is the backbone of modern software delivery. Continuous Integration catches bugs early. Continuous Deployment gets features to users fast. But poorly designed pipelines can be slow, flaky, and a source of constant frustration. This skill covers GitHub Actions (the most popular), GitLab CI, and general pipeline design principles. The focus is on pipelines that are fast, reliable, and maintainable. 2025 reality: Your pipeline is infrastructure code. It deserves the same care as your application. A flaky test in CI is worse than no test - it teaches developers to ignore failures. Use when "github actions, gitlab ci, ci cd, pipeline, workflow, deploy automation, continuous integration, continuous deployment, build pipeline, yaml workflow, ci-cd, github-actions, gitlab-ci, devops, automation, deployment, pipelines" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。