246 件 ・ 関連度順
概要と使いどころ
Plan a huge chunk of work — more than one agent session can hold — as a shared map of decision tickets on your issue tracker, and resolve them one at a time until the way to the destination is clear.
日本語の概要は準備中です。原文の説明を表示しています。
Erstellt oder überarbeitet einen Skill FÜR DIESES ÖKOSYSTEM: delegiert die generische Interview-/Entwurfs-/Eval-Schleife an das offizielle skill-creator-Plugin (Anthropic, Apache-2.0), setzt aber zusätzlich die ellmos-Anforderungen durch, die das offizielle Plugin nicht kennt — Haus-Frontmatter (9 Felder), Kategorie/Sichtbarkeits-Regeln, anbieter-/nutzer-/ellmos-neutrale aber ellmos-sensitive Erkennung via grounding-seed, mitgelieferte config.json (inkl. Lernvertrag) + connections.json, Anbieter-/Vendor-Bewusstsein (State-of-the-Art-Alternativen inkl. eigener ellmos-Komponenten vorschlagen), einen Selbstaktualisierungs-Abschnitt UND einen wiederverwendbaren Lern-/Abdeckungs-Dateisatz (user-usecases.json, usecase-gaps.json, known-providers-and-abilities.json, gap-closing-analysis.json — an skill-creators evals.json und A2A/AgentSkill angelehnt, kein Parallelstandard). IMMER nutzen, wenn ein NEUER Skill für dieses System entstehen oder ein bestehender auf ellmos-Konformität nachgerüstet werden soll — auch bei "erstelle einen Skill", "bau mir einen Skill für X", "skill-creator nutzen", "neuen Skill anlegen", "diesen Skill ellmos-konform machen", "Lernvertrag/Verhaltenscodex für einen Skill anlegen", "Usecase-Abdeckung eines Skills prüfen". Für reines Skill-FINDEN/ROUTEN stattdessen skill-finder, für Landschafts-Audit skill-explorer.
日本語の概要は準備中です。原文の説明を表示しています。
Manages your own skill landscape: surveys and compares existing skills (Audit mode), researches the web for new skills/plugins (Explore mode), and is at the same time the installer that generates lean subskills (Skill-Finder, family umbrella, maintenance skills) instead of loading a monolith. Use this skill for "compare/audit skills", "which skills are duplicated", "form skill families", "clean up/consolidate skills", "maintain the skill register", "find skills/plugins for topic X", "install new skills", "browse the skill marketplace", or for `/skill-explorer`. Delivers a sub-report per family and a globally numbered decision list; installs/uninstalls only after a security check and explicit approval.
日本語の概要は準備中です。原文の説明を表示しています。
Health-check the connected MCP servers and scout new ones: the safe pre-flight before integration work, plus a connector finder. Read-only by default. Triggers: "/mcp", "/mcp health", "/mcp discover <need>", "which MCP servers are alive", "find an MCP for <X>".
日本語の概要は準備中です。原文の説明を表示しています。
Plan a huge chunk of work (more than one agent session can hold) as a shared map of decision tickets on your issue tracker, and resolve them one at a time until the way to the destination is clear.
日本語の概要は準備中です。原文の説明を表示しています。
Performs retrosynthetic planning using AiZynthFinder (MCTS, template-based), Chemformer (template-free transformer), ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, building-block availability (eMolecules, Enamine, Mcule), forward prediction validation (Molecular Transformer), and disconnection-aware multi-objective search (MO-MCTS). Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
日本語の概要は準備中です。原文の説明を表示しています。
Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.
日本語の概要は準備中です。原文の説明を表示しています。
Assigns GO terms, Pfam/InterPro domains, KEGG orthologs, EC numbers, and product names to predicted proteins using eggNOG-mapper (orthology), InterProScan (domain signatures), and KofamScan (KEGG), routing specialized functions to dbCAN/antiSMASH/AMRFinderPlus/SignalP. Covers the orthology-vs-domain-vs-homology paradigms, the annotation-error percolation cascade, domain-presence-is-not-function, GO IEA circularity in enrichment, evidence tiering, and bit-score/coverage thresholds. Use when adding functional annotation to predicted genes, choosing between eggNOG-mapper and InterProScan, or judging how much to trust a functional label.
日本語の概要は準備中です。原文の説明を表示しています。
Assigns isolate identity at the right resolution for the question -- ANI / Mash species triage, 7-locus MLST historical comparability, cgMLST / wgMLST outbreak resolution (chewBBACA, BIGSdb, Ridom SeqSphere, EnteroBase HierCC), in-silico serotyping (SISTR, SeqSero2 for Salmonella; SerotypeFinder for E. coli; Kaptive K/O for Klebsiella; SeroBA for pneumococcus; spa + SCCmec for S. aureus), and lineage callers (TB-Profiler / Mykrobe Coll-Napier barcode for MTBC, Pangolin + Nextclade for SARS-CoV-2, PopPUNK GPSC for S. pneumoniae). Use when typing bacterial isolates for surveillance or outbreak investigation, choosing between cgMLST allele distance and core-SNP distance for cluster definition, harmonising calls across schemas / database versions (chewBBACA vs Ridom vs EnteroBase), assigning MTBC lineage with the Napier 2020 90-SNP barcode, calling Salmonella serovar via SISTR with monophasic Typhimurium awareness, running Pangolin UShER mode with explicit pangolin-data version pinning, or selecting a typing resolution to match the surveillance question.
日本語の概要は準備中です。原文の説明を表示しています。
Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.
日本語の概要は準備中です。原文の説明を表示しています。
Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.
日本語の概要は準備中です。原文の説明を表示しています。
Detect, date, and contextualize whole-genome duplication (WGD / paleopolyploidy) events using wgd v2 (Chen & Zwaenepoel 2024), KsRates (Sensalari 2022 substitution-rate-corrected Ks dating), DupGen_finder (Qiao 2019), MAPS (Li 2018 phylogenomic), POInT (Conant 2008 ordered-block), SLEDGe (2024 ML-based), Whale.jl (Bayesian DTL+WGD), and synteny-anchored paranome construction. Use when identifying ancient polyploidy from Ks distributions and synteny block analysis, positioning WGD events relative to speciation, distinguishing tandem from segmental from WGD duplications, dating the 2R/3R vertebrate / fish / salmonid WGDs, building paranome and Ks-age mixture models, applying KsRates substitution-rate correction across lineages, or testing alternative biased-fractionation / dosage-balance models post-WGD.
日本語の概要は準備中です。原文の説明を表示しています。
Performs retrosynthetic planning using AiZynthFinder (MCTS, template-based), Chemformer (template-free transformer), ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, building-block availability (eMolecules, Enamine, Mcule), forward prediction validation (Molecular Transformer), and disconnection-aware multi-objective search (MO-MCTS). Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
日本語の概要は準備中です。原文の説明を表示しています。
Process and analyze single-cell ATAC-seq data with Signac, ArchR, SnapATAC2, or Cell Ranger ATAC. Use when handling 10X scATAC or 10X Multiome (paired RNA+ATAC) data, performing per-cell QC, choosing between ArchR/Signac/SnapATAC2 ecosystems, building per-cluster consensus peaksets, integrating with paired scRNA-seq, doublet detection (AMULET vs ArchR vs scDblFinder), or running pseudobulk differential accessibility per cluster.
日本語の概要は準備中です。原文の説明を表示しています。
Quantifies alternative splicing as PSI (percent spliced in) from RNA-seq using rMATS-turbo (BAM-based event), SUPPA2 (TPM-based event), MAJIQ V3 (LSV-based Bayesian), leafcutter (annotation-free intron clusters), VAST-TOOLS (cross-species with microexon support), Shiba (junction-imbalance-corrected, 2025 SOTA at low coverage), or IRFinder-S (intron retention coverage-aware). Distinguishes the five canonical event classes (SE, A5SS, A3SS, MXE, RI), special classes (microexons, exitrons, AFE/ALE), intron retention subtypes (canonical RI vs detained introns), and applies effective-length normalization. Use when measuring splice-site usage or isoform inclusion ratios from short-read RNA-seq.
日本語の概要は準備中です。原文の説明を表示しています。
Performs a final quality pass fixing alignment, spacing, consistency, and micro-detail issues before shipping. Use when the user mentions polish, finishing touches, pre-launch review, something looks off, or wants to go from good to great.
日本語の概要は準備中です。原文の説明を表示しています。
Create Convex queries, mutations, and actions with proper validation, authentication, and error handling. Use when implementing new API endpoints.
日本語の概要は準備中です。原文の説明を表示しています。
Adapt designs to work across different screen sizes, devices, contexts, or platforms. Implements breakpoints, fluid layouts, and touch targets. Use when the user mentions responsive design, mobile layouts, breakpoints, viewport adaptation, or cross-device compatibility.
日本語の概要は準備中です。原文の説明を表示しています。
Strip designs to their essence by removing unnecessary complexity. Great design is simple, powerful, and clean. Use when the user asks to simplify, declutter, reduce noise, remove elements, or make a UI cleaner and more focused.
日本語の概要は準備中です。原文の説明を表示しています。
Pushes interfaces past conventional limits with technically ambitious implementations — shaders, spring physics, scroll-driven reveals, 60fps animations. Use when the user wants to wow, impress, go all-out, or make something that feels extraordinary.
日本語の概要は準備中です。原文の説明を表示しています。
Agent Ready project design context for navigation, docs links, and interface tone. Use when building or reviewing UI in this repo so patterns match the documented product feel.
日本語の概要は準備中です。原文の説明を表示しています。
Amplify safe or boring designs to make them more visually interesting and stimulating. Increases impact while maintaining usability. Use when the user says the design looks bland, generic, too safe, lacks personality, or wants more visual impact and character.
日本語の概要は準備中です。原文の説明を表示しています。
Builds reusable Convex components with isolated tables and app-facing APIs. Use for new components, reusable backend modules, integrations, or component boundary work.
日本語の概要は準備中です。原文の説明を表示しています。
Build reactive, type-safe, production-grade backends. ALWAYS use this skill when the user asks to build, plan, design, or implement backend features, APIs, data models, server logic, database schemas, web apps, full stack apps, or mobile apps. This includes planning and architecture discussions.
日本語の概要は準備中です。原文の説明を表示しています。