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概要と使いどころ
Compute well-defined metrics from existing formulas, datasets, or test outputs. Use as an explicit/manual helper when the metric definition is already known, not for choosing the overall analysis owner or dashboard strategy.
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Comprehensive markdown and Mermaid diagram writing skill that establishes text-based diagrams as the DEFAULT documentation standard. Use this skill when creating ANY scientific document, report, analysis, or visualization — it ensures all outputs are in version-controlled, token-efficient markdown with embedded Mermaid diagrams as the source of truth, with clear pathways to downstream Python or AI-generated images. Includes full style guides (markdown + mermaid), 24 diagram type references, and 9 document templates ready to use.
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Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
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Use whenever the agent creates, writes, moves, or renames a file in a team/delegate (shared) workspace, OR when the user asks to organize, clean up, restructure, audit, or find files in any workspace or the Vault, OR when starting a multi-file task or named project. Enforces a purpose-based folder convention (flat mode: notes/, data/, outputs/, scripts/, archive/; project mode: projects/<slug>/{docs,assets,source,reports,research}/), per-agent namespacing under shared/<agent_key>/, and pre-write discovery via memory_search, vault_search, knowledge_graph_search to surface related files and avoid duplicates. Trigger before any write_file or exec at workspace root, when starting a project, generating reports/assets/exports, delegating, or when the user says "messy", "where did I save", "tổ chức lại", "dọn workspace", "tạo report", "find related", "search vault". Do NOT trigger for read-only ops, edits inside an existing project tree (cloned repo), or short-lived files deleted in the same turn.
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Generate and analyze DNA sequences using NVIDIA's Evo 2 BioNeMo NIM microservice. Use for Evo2/Evo 2, DNA generation, genomic sequence generation, hosted generation, local Docker deployment, local forward passes, layer outputs, logits, sampled probabilities, and BioNeMo NIM workflows.
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Run RFDiffusion protein backbone design via NVIDIA NIM. Use for de novo protein backbones, motif scaffolding, binder design, hotspot residues, contigs syntax, diffusion steps, hosted NVIDIA API calls, local Docker deployment, and PDB backbone outputs for ProteinMPNN sequence design.
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Use this skill when OpenStoryline is already installed and the user wants to start the local MCP/Web services, create or continue a session, send editing instructions, perform multi-turn re-editing, and verify rendered video outputs, as well as Chinese requests like “启动 OpenStoryline”, “把 OpenStoryline 跑起来”, “用 OpenStoryline 剪视频”.
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[omh] LLM-powered feature to build: LLM app development: prepare a build handoff for an LLM-powered feature with a pinned provider boundary, schema-first outputs, versioned prompt files, grounded retrieval, and an eval suite as a shipped deliverable. Use when the user says: llm-app-dev, llm app development, llm application development, build an llm app, build an llm feature, llm feature development, build a rag pipeline, rag pipeline.
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Query the Reactome database (Analysis and Content Services). Use when the user asks about pathway analysis, gene list enrichment, retrieving results by token, finding unmapped or not-found identifiers, mapping identifiers, reaction participants (inputs, outputs), pathway hierarchy (including top-level pathways), diagram export, cross-reference mapping, or searching the knowledgebase.
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Best practices for working on the Harness books repo. Use this skill when editing, restructuring, building, or exporting the books under `book1-claude-code/` and `book2-comparing/`, especially for Honkit, print HTML, Pandoc/XeLaTeX PDF export, build cleanup, TOC issues, naming conventions, and keeping source assets separate from generated outputs.
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Converts VitePress/GFM wiki markdown to Azure DevOps Wiki-compatible format. Generates a Node.js build script that transforms Mermaid syntax, strips front matter, fixes links, and outputs ADO-compatible copies to dist/ado-wiki/.
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Build Azure AI Foundry agents using the Microsoft Agent Framework Python SDK (agent-framework-azure-ai). Use when creating persistent agents with AzureAIAgentsProvider, using hosted tools (code interpreter, file search, web search), integrating MCP servers, managing conversation threads, or implementing streaming responses. Covers function tools, structured outputs, and multi-tool agents.
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Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt. Use when starting a proteomics analysis with raw or processed MS data. Handles contaminant filtering and missing value assessment.
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Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples. Outputs differentially bound regions with fold changes and p-values. Use when comparing ChIP-seq binding between conditions.
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Validate multi-skill workflows defined in CLAUDE.md by checking skill existence, inter-skill data contracts (JSON schema compatibility), file naming conventions, and handoff integrity. Use when adding new workflows, modifying skill outputs, or verifying pipeline health before release.
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Track investment theses across their lifecycle — from screening idea to closed position with postmortem. Register theses from screener outputs, manage state transitions, attach position sizing, review due dates, and generate postmortem reports with P&L and MAE/MFE analysis. Trigger when user says "register thesis", "track this idea", "thesis status", "review due", "close position", "postmortem", or "trading journal".
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Build a Stockbee-style setup model book from momentum-burst screener candidates, then update 3-day and 5-day forward outcomes with MFE/MAE, stop-hit status, outcome tags, and cohort statistics. Use when the user wants to study Stockbee Momentum Burst examples, track failed candidates, build setup fluency, review A/B setup quality, or convert screener outputs into a learning loop rather than immediate trade signals.
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Fetch upcoming economic events and data releases using FMP API. Retrieve scheduled central bank decisions, employment reports, inflation data, GDP releases, and other market-moving economic indicators for specified date ranges (default: next 7 days). The script outputs raw JSON or text; the assistant filters, assesses impact, and generates the Markdown report.
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Critically review strategy drafts from edge-strategy-designer for edge plausibility, overfitting risk, sample size adequacy, and execution realism. Use when strategy_drafts/*.yaml exists and needs quality gate before pipeline export. Outputs PASS/REVISE/REJECT verdicts with confidence scores.
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Use when the user asks to "plan my site structure", "design the page hierarchy / navigation / URL taxonomy", "fix internal linking", or "find orphan pages"; runs two modes — architecture (hierarchy, nav, URL patterns, hub/spoke clusters, Mermaid site maps) and linking (link graph, authority flow, anchor text, orphan disposition, source/target/anchor plan) — and outputs a structure score /100 plus a handoff summary. Not for external backlinks — use offsite-signal-analyzer; not for XML sitemap or indexation issues — use technical-seo-checker. 网站架构/信息架构/站点地图/内链优化
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Render a self-contained HTML viewer for a pro-workflow wiki. Pages, sources, claims, seed queue, page-link graph and full-text search all in one file. No external dependencies, no JS framework, S3-uploadable. Use when the user wants to browse a wiki visually, share its current state with someone, audit research progress, or hand off a knowledge base. Inspired by Thariq Shihipar's "Unreasonable Effectiveness of HTML" — favors information density and shareability over markdown-only outputs.
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Build and deploy full-stack web and mobile apps with AWS Amplify Gen2 (TypeScript code-first). Covers auth (Cognito), data (AppSync/DynamoDB), storage (S3), functions, APIs, and AI (Amplify AI Kit with Bedrock). Supports React, Next.js, Vue, Angular, React Native, Flutter, Swift, and Android. Always use this skill for Amplify Gen2 topics — even for questions you think you know — it contains validated, version-specific patterns that prevent common mistakes. TRIGGER when: user mentions Amplify Gen2; project has amplify/ directory or amplify_outputs; code imports @aws-amplify packages; user asks about defineBackend, defineAuth, defineData, defineStorage, defineFunction, or npx ampx. SKIP: Amplify Gen1 (amplify CLI v6), standalone SAM/CDK without Amplify (use aws-serverless), direct Bedrock without Amplify AI Kit (use bedrock).
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Set up iterative design-to-code development loop with Anima SDK. Use when rapidly iterating on Figma-to-code output, comparing framework outputs, or building a local preview server for generated components. Trigger with: "anima local dev", "anima dev loop", "anima preview", "anima iteration".
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Detect keyword cannibalization across blog posts by extracting primary keywords from titles and headings, clustering semantically similar targets, and flagging posts competing for the same search intent. Supports local-only mode (grep-based) and DataForSEO API mode (Page Intersection endpoint at ~$0.01/call). Outputs severity-scored report with merge or differentiate recommendations. Use when user says "cannibalization", "keyword overlap", "competing pages", "duplicate keywords", "cannibalize".
日本語の概要は準備中です。原文の説明を表示しています。