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Computer vision for bio-image preprocessing, feature detection, real-time microscopy. Color conversion, morphology, contour/blob detection, template matching, optical flow on fluorescence/brightfield. 10-100× faster than pure Python via C++. Use scikit-image for scientific morphometry/regionprops; OpenCV for real-time, video, classical feature extraction.

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Guide for choosing and creating scientific visualizations for publications and talks. Covers chart-type selection by data structure, color theory for accessibility/print, figure composition, journal formatting (Nature, Cell, ACS), and common pitfalls. Consult when visualizing data or preparing submission figures.

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Python image processing for microscopy and bioimage analysis. Read/write images, filter (Gaussian, median, LoG), segment (thresholding, watershed, active contours), measure region properties, detect features. SciPy/NumPy ecosystem. Use OpenCV for real-time video; CellPose for DL cell segmentation; napari for visualization.

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Time-to-event modeling with scikit-survival: Cox PH (elastic net), Random Survival Forests, Boosting, SVMs for censored data. C-index, Brier, time-dependent AUC; Kaplan-Meier, Nelson-Aalen, competing risks. Pipeline/GridSearchCV compatible. Use statsmodels for frequentist, pymc for Bayesian, lifelines for parametric.

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Use Cookiecutter Data Science to generate, configure, validate, and troubleshoot reproducible data-science project templates and generated project workflows.

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Sci-fi and punk world art direction for Blender including hard sci-fi, space, cyberpunk, steampunk, dieselpunk, atompunk, solarpunk, biopunk, and clockpunk.

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Create, implement, or review plantuml ascii work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on plantuml ascii.

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A terminal-native marketing system rendered entirely in Berkeley Mono — every word on the page, from the hero headline down to the footer fine print, is monospaced. The page itself reads like a manpage or a static-site README: warm cream canvas (`#fdfcfc`), nearly-black ink (`#201d1d`), 4px-radius rectangles for the few interactive elements, and bracketed `[+]`/`[-]` ASCII markers used as bullets. The brand's only "visual moment" is a single dark hero card that mocks up the OpenCode TUI itself — black background, monospaced terminal output, ASCII pipe characters, and a wordmark rendered as block-pixel ASCII. Every section sits as a hairline-bordered text block on the cream canvas with no shadows, no gradients, no decorative imagery, and no non-monospaced character anywhere in the system.

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Produce an intensive, cited analytical report: executive summary, multi-angle findings, contrarian views, open questions, and full sources. Use only when the user needs rigorous synthesis of a complex topic (scientific, technical, policy, or market-analytical) that cannot be answered with a short search, and wants a formal written report, not a recommendation list. Do not use for product picks, top-N lists, quick lookups, or routine "find out about X" tasks. If the request does not clearly need this kind of report, do not use this skill. Do not use for a literature review over published papers. This skill collects evidence from the open web. A request for the literature on a biomedical, clinical, life-science, or other scientific topic — papers, studies, trials, preprints — belongs to firecrawl-research-papers, which queries Firecrawl's paper index (PubMed, bioRxiv, medRxiv, arXiv) instead of searching websites.

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Build AI agents that automate scientific research — hypothesis generation, experiment design, data analysis, and paper writing using agentic tree search. Use when: automating research workflows, generating and testing hypotheses, building AI-powered research assistants.

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软件架构 (含 应用架构 / 系统架构 / 分布式 后端架构 / 前后端 数据流 与 数据模型 设计 / API 边界 / 可扩展性 / 演进式架构 — 不含 硬件架构 / 纯企业架构 / 纯 DevOps / 纯安全架构) (software architecture — application & system architecture for web / mobile / distributed back-ends; designing services + data models + data flow + integration boundaries; making explicit trade-offs about scalability / coupling / consistency / evolvability; not hardware / chip architecture, not pure enterprise-architecture (TOGAF/Zachman), not pure DevOps / SRE, not pure security architecture (those are adjacent disciplines).) Master OS — automated mastery of software architecture — application & system architecture for web / mobile / distributed back-ends; designing services + data models + data flow + integration boundaries; making explicit trade-offs about scalability / coupling / consistency / evolvability; not hardware / chip architecture, not pure enterprise-architecture (TOGAF/Zachman), not pure DevOps / SRE, not pure security architecture (those are adjacent disciplines).: top builders' mental models, tool stack, current workflows, jargon, and where to keep up. Trigger this skill when the user works on software architecture — application & system architecture for web / mobile / distributed back-ends; designing services + data models + data flow + integration boundaries; making explicit trade-offs about scalability / coupling / consistency / evolvability; not hardware / chip architecture, not pure enterprise-architecture (TOGAF/Zachman), not pure DevOps / SRE, not pure security architecture (those are adjacent disciplines). problems and wants industry-grade thinking, tool selection, or workflow guidance. 触发词：「软件架构」「系统设计」「system design」「应用架构」「service design」

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中医诊疗 — 中医临床医师的认知操作系统 (经典理论 阴阳五行脏腑气血经络六经卫气营血三焦 + 四诊八纲 + 治法 + 方剂学 经方时方 + 中药学 四气五味归经炮制 + 针灸学 经络穴位手法灸法 + 推拿按摩 + 中医各科 内外妇儿骨伤皮肤眼耳鼻喉肛肠老年急症 + 中西医结合 + 循证中医 + NATCM 监管 + 中医诊所备案 + 国家级名老中医 学术继承人 — 不含 道家修炼 / 风水算命 / 中医养生科普 / 中医美容 / 民族医学藏蒙维傣) (Traditional Chinese Medicine (TCM) clinical practice — the cognitive operating system of practicing TCM physicians covering (a) 经典理论 (阴阳/五行/脏腑/气血津液/经络/六淫/七情/六经/卫气营血/三焦) classical theory, (b) 四诊 (望闻问切) clinical observation/inquiry/pulse + 八纲 (阴阳/表里/寒热/虚实) syndrome differentiation, (c) 治法 (汗吐下和温清消补 + 扶正祛邪) therapeutic principles, (d) 方剂学 (经方 时方 验方) formula science, (e) 中药学 (四气五味/归经/七情/炮制/配伍禁忌) materia medica, (f) 针灸学 (经络穴位/手法/灸法/电针) acupuncture+moxibustion, (g) 推拿按摩 tuina massage, (h) 中医各科 (内/外/妇/儿/骨伤/皮肤/眼/耳鼻喉/肛肠/老年/急症) clinical specialties, (i) 中西医结合 integrative medicine, (j) 循证中医 + 临床流行病学 evidence-based TCM + 现代研究, (k) 中医诊所备案 / 中医师资格 / NATCM 监管 / 药典 / GMP regulatory framework, (l) 国家级名老中医 学术继承人 项目 transmission program; NOT 道家修炼 / 风水 / 算命八字 (那是 玄学不是 中医), NOT 中医养生科普 (是 衍生 不是 临床主体), NOT 中医美容 (是 商业化分支), NOT 民族医学 (藏蒙维傣 是 平行体系 不在本 skill 主线 — 仅作 边界标注).) Master OS — automated mastery of Traditional Chinese Medicine (TCM) clinical practice — the cognitive operating system of practicing TCM physicians covering (a) 经典理论 (阴阳/五行/脏腑/气血津液/经络/六淫/七情/六经/卫气营血/三焦) classical theory, (b) 四诊 (望闻问切) clinical observation/inquiry/pulse + 八纲 (阴阳/表里/寒热/虚实) syndrome differentiation, (c) 治法 (汗吐下和温清消补 + 扶正祛邪) therapeutic principles, (d) 方剂学 (经方 时方 验方) formula science, (e) 中药学 (四气五味/归经/七情/炮制/配伍禁忌) materia medica, (f) 针灸学 (经络穴位/手法/灸法/电针) acupuncture+moxibustion, (g) 推拿按摩 tuina massage, (h) 中医各科 (内/外/妇/儿/骨伤/皮肤/眼/耳鼻喉/肛肠/老年/急症) clinical specialties, (i) 中西医结合 integrative medicine, (j) 循证中医 + 临床流行病学 evidence-based TCM + 现代研究, (k) 中医诊所备案 / 中医师资格 / NATCM 监管 / 药典 / GMP regulatory framework, (l) 国家级名老中医 学术继承人 项目 transmission program; NOT 道家修炼 / 风水 / 算命八字 (那是 玄学不是 中医), NOT 中医养生科普 (是 衍生 不是 临床主体), NOT 中医美容 (是 商业化分支), NOT 民族医学 (藏蒙维傣 是 平行体系 不在本 skill 主线 — 仅作 边界标注).: top builders' mental models, tool stack, current workflows, jargon, and where to keep up. Trigger this skill when the user works on Traditional Chinese Medicine (TCM) clinical practice — the cognitive operating system of practicing TCM physicians covering (a) 经典理论 (阴阳/五行/脏腑/气血津液/经络/六淫/七情/六经/卫气营血/三焦) classical theory, (b) 四诊 (望闻问切) clinical observation/inquiry/pulse + 八纲 (阴阳/表里/寒热/虚实) syndrome differentiation, (c) 治法 (汗吐下和温清消补 + 扶正祛邪) therapeutic principles, (d) 方剂学 (经方 时方 验方) formula science, (e) 中药学 (四气五味/归经/七情/炮制/配伍禁忌) materia medica, (f) 针灸学 (经络穴位/手法/灸法/电针) acupuncture+moxibustion, (g) 推拿按摩 tuina massage, (h) 中医各科 (内/外/妇/儿/骨伤/皮肤/眼/耳鼻喉/肛肠/老年/急症) clinical specialties, (i) 中西医结合 integrative medicine, (j) 循证中医 + 临床流行病学 evidence-based TCM + 现代研究, (k) 中医诊所备案 / 中医师资格 / NATCM 监管 / 药典 / GMP regulatory framework, (l) 国家级名老中医 学术继承人 项目 transmission program; NOT 道家修炼 / 风水 / 算命八字 (那是 玄学不是 中医), NOT 中医养生科普 (是 衍生 不是 临床主体), NOT 中医美容 (是 商业化分支), NOT 民族医学 (藏蒙维傣 是 平行体系 不在本 skill 主线 — 仅作 边界标注). problems and wants industry-grade thinking, tool selection, or workflow guidance. 触发词：「中医」「中医学」「中医药」「中医诊疗」「中医临床」

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Produce an intensive, cited analytical report: executive summary, multi-angle findings, contrarian views, open questions, and full sources. Use only when the user needs rigorous synthesis of a complex topic (scientific, technical, policy, or market-analytical) that cannot be answered with a short search, and wants a formal written report, not a recommendation list. Do not use for product picks, top-N lists, quick lookups, or routine "find out about X" tasks. If the request does not clearly need this kind of report, do not use this skill. Do not use for a literature review over published papers. This skill collects evidence from the open web. A request for the literature on a biomedical, clinical, life-science, or other scientific topic — papers, studies, trials, preprints — belongs to firecrawl-research-papers, which queries Firecrawl's paper index (PubMed, bioRxiv, medRxiv, arXiv) instead of searching websites.

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Anchor a multidisciplinary unit in a real-world phenomenon that requires multiple subject lenses to understand. Use when designing integrated or phenomenon-based units across disciplines.

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Design discipline-specific critical thinking tasks grounded in knowledge-contingent reasoning rather than generic skills. Use when embedding higher-order thinking into subject content.

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Design a sequence where students compare AI's handling of the same question across disciplines, developing a mental model of where AI is reliable vs. distorting based on knowledge type.

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ASCII 艺术：pyfiglet、cowsay、boxes、图像转 ASCII。

日本語の概要は準備中です。原文の説明を表示しています。

ASCII art: pyfiglet, cowsay, boxes, image-to-ascii.

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ASCII video: convert video/audio to colored ASCII MP4/GIF.

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ASCII 视频：将视频/音频转换为彩色 ASCII MP4/GIF。

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Use when interpreting research findings, evaluating scientific evidence, analyzing mechanisms, comparing competing hypotheses, designing experiments, or constructing scientific arguments.

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Act as an end-to-end data scientist: turn business questions into defensible analysis, validated models, and decision-ready reports. Use whenever the user asks to analyze, explore, or profile a dataset or CSV/Parquet/Excel file; asks what drives a metric or why a number changed ("why did churn go up?"); wants to test whether a difference is real (A/B tests, experiments, "is this significant?", "how many samples do I need?"); wants a predictive model (churn, forecast, scoring, segmentation, classification, regression); asks to review an existing analysis, notebook, or model for flaws; or needs results written up for decision-makers. Triggers in any language ("phân tích dữ liệu", "xây model dự đoán", "kiểm định A/B"), even when they never say "data science" or "statistics".

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Orchestrator context window discipline enforcement. Prevents the orchestrator from reading source files it will not edit, running diagnostic commands that waste context, and rationalizing delegation bypasses. Use when setting up orchestrator guardrails, reviewing delegation discipline, or diagnosing context window waste in multi-agent workflows. Activates PreToolUse hooks that surface decision points before source file reads and diagnostic command execution.

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Apply WIT (Writing Is Thinking) as a human–LLM collaborative scientific reasoning skill for scientific question formulation, finding-driven research planning, next-experiment selection, Results or Discussion review, claim–evidence and reviewer stress tests, manuscript logic audits, deadline closure, and researcher growth. Use when the user invokes WIT or asks for these question-driven scientific reasoning workflows; do not use for generic copyediting, summarization, or literature search alone.

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