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概要と使いどころ
Preprocessing and harmonization of multi-omics data before integration. Covers normalization, batch correction, feature alignment, and missing value handling across data types. Use when preparing multi-omics datasets for integration analysis.
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Multi-Omics Factor Analysis (MOFA2) for unsupervised integration of multiple data modalities. Identifies shared and view-specific sources of variation. Use when integrating RNA-seq, proteomics, methylation, or other omics to discover latent factors driving biological variation across modalities.
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Alpha and beta diversity analysis for microbiome data. Calculate within-sample richness, evenness, and between-sample dissimilarity with phyloseq and vegan. Use when comparing community composition across samples or testing for group differences in microbiome structure.
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Visualize copy number profiles, segments, and compare across samples. Create publication-quality plots of CNV data from CNVkit, GATK, or other callers. Use when creating genome-wide CNV plots, sample heatmaps, or chromosome-level visualizations.
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Bead-based normalization for CyTOF and high-parameter flow cytometry. Covers EQ bead normalization, signal drift correction, and batch normalization. Use when correcting instrument drift in CyTOF or harmonizing data across batches.
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JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens) for modeling sgRNA efficacy and gene essentiality. Use when analyzing multiple CRISPR screens simultaneously or when accounting for variable sgRNA efficiency across experiments.
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Batch effect correction for CRISPR screens. Covers normalization across batches, technical replicate handling, and batch-aware analysis. Use when combining screens from multiple batches or correcting systematic technical variation.
日本語の概要は準備中です。原文の説明を表示しています。
Process multiple sequence files in batch using Biopython. Use when working with many files, merging/splitting sequences, or automating file operations across directories.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze transcription factor motif accessibility variability using chromVAR. Use when identifying which TF motifs show variable accessibility across samples or conditions in ATAC-seq data.
日本語の概要は準備中です。原文の説明を表示しています。
Track investment theses across their lifecycle — from screening idea to closed position with postmortem. Register theses from screener outputs, manage state transitions, attach position sizing, review due dates, and generate postmortem reports with P&L and MAE/MFE analysis. Trigger when user says "register thesis", "track this idea", "thesis status", "review due", "close position", "postmortem", or "trading journal".
日本語の概要は準備中です。原文の説明を表示しています。
Detect and analyze trending market themes across sectors. Use when user asks about current market themes, trending sectors, sector rotation, thematic investing, what themes are hot or cold, or wants to identify bullish and bearish market narratives with lifecycle analysis.
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Select the best MetaTrader 5 trading robots (Expert Advisors) that have not been backtested yet, by running the MT5 Strategy Tester from the command line through a 3-round pipeline. Use when the user wants to batch-test MT5 bots/EAs, screen robots across all symbols, optimize EA parameters, or move candidate bots to finalists based on profit, drawdown, positive months/years and equity-curve criteria. Runs terminal64.exe headless; Windows + MetaTrader 5 required at run time.
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Review skills in any project using a dual-axis method: (1) deterministic code-based checks (structure, scripts, tests, execution safety) and (2) LLM deep review findings. Use when you need reproducible quality scoring for `skills/*/SKILL.md`, want to gate merges with a score threshold (for example 90+), or need concrete improvement items for low-scoring skills. Works across projects via --project-root.
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Quantifies market breadth health using TraderMonty's public CSV data. Generates a 0-100 composite score across 6 components (100 = healthy). No API key required. Use when user asks about market breadth, participation rate, advance-decline health, whether the rally is broad-based, or general market health assessment.
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Quantifies crypto market regime health using free, keyless public data (CoinGecko + Binance funding). Generates a 0-100 composite score across 6 components (100 = risk-on) with a posture recommendation. No API key required. Use when user asks about crypto market conditions, whether it's alt season, BTC dominance, crypto risk-on vs risk-off, funding rates, or whether crypto exposure should be increased or reduced.
日本語の概要は準備中です。原文の説明を表示しています。
Detect crowded speculative positioning in CFTC futures markets (COT report analysis) to find contrarian setups using Jason Shapiro's methodology. Screens large-speculator ("non-commercial") net positioning across 65 futures markets (indices, rates, FX, metals, energy, crypto) via the FMP Commitment of Traders API, computes a 3-year and 26-week COT Index per market, and classifies extremes as CROWDED_LONG / CROWDED_SHORT. Use when the user asks about COT report analysis, crowded positioning, "who is trapped", speculative positioning extremes, contrarian futures setups, or wants to run Jason Shapiro-style analysis. This skill automates crowding DETECTION only (step 1 of 5) — it does not generate trade signals by itself.
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Your long-term knowledge pages. Read them at session start. Create new pages when you learn something worth remembering across sessions. Pages auto-update from your conversations via Hindsight.
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Use when the user asks to "run the weekly social readout", "which denominator does our engagement rate use", or "which posts won this week and what changes next cycle"; produces the organic-social metric dictionary (every rate names its denominator — ERR engagement-by-reach vs ERI by-impressions vs ER-by-follower — locked across periods), median-not-mean per-post rollups with organic and boosted separated, EMV as labeled exec-translation only (never inside any score), an attributed CHAOSS/Orbit-style community-health readout with employees excluded, and the best/worst-performer write-back the next calendar cycle consumes. Not for dollar-ROI math or the ECHO profile result gate verdict — use roi-calculator and social-quality-auditor. 社媒周报/互动率分母/指标字典/复盘回写
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Use when the user asks to "create an influencer brief" or "write a campaign brief"; produces a structured creator brief with deliverables, key messages, creative direction, timeline, disclosure rules, and compensation terms. Not for choosing how to split spend across creators — use budget-optimizer. 达人合作简报/创作者BF
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Use when the user asks to "allocate my influencer budget", "optimize spend across tiers", or "compare budget scenarios"; produces a tier/platform/content allocation table, ROI and CPM/CPE projections, scenario comparisons, and mid-campaign reallocation moves. Not for building the full campaign plan — use campaign-planner. 达人预算分配/投放预算优化
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Use when the user asks to "build audience segments from my customer list", "make value-based / lookalike seed lists", "set up exclusion / suppression segments", or "map audiences to funnel stages across platforms"; turns the user's OWN customer/CRM/GA4 export into seed audiences, value-based lookalike SEED lists, exclusion/suppression segments, and a cross-platform funnel-stage targeting map, informing the ROAS A (Audience) dimension. Not for building account structure or match types — use campaign-architect; not for organic SERP intent — use keyword-research. 付费广告受众分群/种子人群/排除人群/相似人群种子
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Use when the user asks to "remember project context", review saved findings, initialize runtime memory, archive stale work, reconcile notes, or erase a subject; manages authorized HOT/WARM/COLD working memory across all disciplines while preserving registry event ownership and privacy controls. Not for changing canonical registry facts - route those through the owning registry. 项目记忆/跨会话
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Use when the user asks to "pick a bid strategy", "set a tCPA/tROAS target", or "plan the learning-phase entry"; produces a bid-strategy choice (tCPA / tROAS / max-conversions / manual CPC), the starting target math, a portfolio grouping map, and a learning-phase entry plan. Not for splitting the budget across campaigns — use budget-optimizer; not for in-flight pacing/scale moves — use budget-pacing-monitor; not for scoring the account — use ad-account-auditor. 出价策略/tCPA目标/tROAS/学习期
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Use when the user asks to "generate subject line variants", "pre-score my subject lines", or "will this subject get truncated / trigger spam filters"; produces a labeled subject + preheader variant set and a per-variant heuristic pre-score card — spam-trigger flags, length/truncation across desktop + mobile, emoji-count, and the inbox preview render (from-name + subject + preheader) — before any test is run. Not for the body copy or CTA — use email-creative-builder; not for the A/B test design or significance read — use send-experiment-designer; not for the profile-weighted EQS or the S1/S2/N1/D1 vetoes — use email-quality-auditor. 邮件主题行生成/主题行预打分/截断与垃圾词检查
日本語の概要は準備中です。原文の説明を表示しています。