「database」の検索結果

Create, implement, deploy, and debug Adobe Runtime actions with consistent layout, validation, and error handling. Use this skill whenever the user needs to add actions to an App Builder project, understand action structure (params, response format, web/raw actions), configure actions in the manifest, use App Builder SDKs (State, Files, Events, database), deploy and invoke actions via CLI, debug action issues, or implement patterns such as webhook receivers, custom event providers, journaling consumers, large payload redirects, action sequence pipelines, and Asset Compute workers. Also trigger when users mention serverless functions in Adobe context, action logging, IMS authentication for actions, or cron-style scheduled actions.

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Change persistent models and SQLite/PostgreSQL migrations without breaking existing servers.

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Generate realistic, correctly-linked Frappe/ERPNext test records for any DocType using the `bench faker` CLI, then roll them back when done. Use when a test, demo, or local repro needs seed data and the site is missing it — e.g. "I need some Sales Orders", "seed data so I can test this API", "create test Employees in Chennai", or "populate the database to test this endpoint".

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Measure, profile, and fix performance bottlenecks — Core Web Vitals, backend latency, bundle size, and database queries. Load when performance requirements exist, users report slowness, profiling reveals bottlenecks, or the user asks to optimize load time, LCP, INP, CLS, or response time. Not for premature optimization without evidence. Pairs with browser-testing-with-devtools and ci-cd-and-automation for regression guards.

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Prisma Postgres setup and operations guidance across Console, create-db CLI, Management API, and Management API SDK. Use when creating Prisma Postgres databases, working in Prisma Console, provisioning with create-db/create-pg/create-postgres, or integrating programmatic provisioning with service tokens or OAuth.

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Prisma ORM CLI commands reference covering init, generate, migrate, db, dev, complete, studio, validate, format, debug, and mcp. Use for ORM/database CLI workflows, not the Prisma Platform CLI. Triggers on "prisma init", "prisma generate", "prisma migrate", "prisma db", "prisma complete", "prisma studio", "prisma mcp".

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Build and deploy applications when the user selects or invokes the Prisma plugin, including requests like "Build a simple Todo app and deploy it" that do not name a stack. Use Prisma Composer for new apps and Prisma Compute for deployment. Also use for explicit Composer/Compute requests, deployment diagnostics, and recovering Composer deployments. Does not cover unrelated ORM or database administration.

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Prisma Client API reference covering model queries, filters, operators, and client methods. Use when writing database queries, using CRUD operations, filtering data, or configuring Prisma Client. Triggers on "prisma query", "findMany", "create", "update", "delete", "$transaction".

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Connect Codex to any app via the Composio CLI. Send emails, create issues, post messages, update databases - take real actions across Gmail, Slack, GitHub, Notion, and 1000+ services from the terminal.

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Backend architecture patterns, API design, database optimization, and server-side best practices for Node.js, Express, and Next.js API routes.

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Biopython is a comprehensive set of freely available Python tools for biological computation. It provides functionality for sequence manipulation, file I/O, database access, structural bioinformatics, phylogenetics, and many other bioinformatics tasks.

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ClickHouse database patterns, query optimization, analytics, and data engineering best practices for high-performance analytical workloads.

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Azure MySQL Flexible Server SDK for .NET. Database management for MySQL Flexible Server deployments.

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You are a senior backend engineer operating production-grade services under strict architectural and reliability constraints. Use when routes, controllers, services, repositories, express middleware, or prisma database access.

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Connect to Azure Database for PostgreSQL Flexible Server from Node.js/TypeScript using the pg (node-postgres) package.

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Azure PostgreSQL Flexible Server SDK for .NET. Database management for PostgreSQL Flexible Server deployments.

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Azure Cosmos DB SDK for Java. NoSQL database operations with global distribution, multi-model support, and reactive patterns.

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Deploy web apps with backend APIs, database, and file storage. Use when the user asks to deploy or publish a website or web app and wants a public URL. Uses HTTP API via curl.

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Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model. Covers bedtools fisher (analytic 2x2 screen), bedtools shuffle + jaccard permutation, GAT (isochore/GC-conditioned simulation with FDR), regioneR (flexible permutation, randomizeRegions vs circularRandomizeRegions, localZScore), LOLA (universe-relative Fisher against a region database), and GREAT/rGREAT (regulatory-domain binomial + hypergeometric for ontology-from-regions). Stresses the universe/background choice, matched background, blacklist exclusion, and multiple-testing control. Use when asking whether peaks/regions are enriched at enhancers/TFBS/features, scoring region-set colocalization or region-set enrichment, comparing CNV/SV concordance, or turning an overlap count into a defensible p-value.

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Infer or annotate TCR antigen specificity by unsupervised clustering (TCRdist/tcrdist3, GLIPH2, clusTCR, GIANA) and database lookup (VDJdb, IEDB, McPAS-TCR), and rank candidates with supervised predictors (ERGO-II, NetTCR-2.x, pMTnet) under explicit caveats. Encodes the central truth that general TCR-epitope prediction for UNSEEN epitopes essentially does not work (collapses to near-random; IMMREP22, Grazioli 2022) because labeled data is dominated by a few immunodominant epitopes and there is no true negative set — so clustering for discovery is the honest task and de-novo binding needs wet-lab validation. Use when annotating TCR specificity or grouping a repertoire. Epitope/MHC context lives in mhc-binding-prediction.

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Infer transcription factor regulons from single-cell RNA-seq with pySCENIC by combining GRNBoost2 co-expression, cisTarget motif-enrichment pruning, and AUCell per-cell activity scoring. Covers the motif-pruning-as-directionality principle, regulon specificity scoring, run-to-run stability, and database/species matching. Use when identifying TF regulons, scoring TF activity per cell, finding master regulators of cell identity, or comparing regulon activity across conditions. For enhancer-driven multiomic GRNs see multiomics-grn; for bulk inference and VIPER protein-activity see grn-inference.

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Assigns isolate identity at the right resolution for the question -- ANI / Mash species triage, 7-locus MLST historical comparability, cgMLST / wgMLST outbreak resolution (chewBBACA, BIGSdb, Ridom SeqSphere, EnteroBase HierCC), in-silico serotyping (SISTR, SeqSero2 for Salmonella; SerotypeFinder for E. coli; Kaptive K/O for Klebsiella; SeroBA for pneumococcus; spa + SCCmec for S. aureus), and lineage callers (TB-Profiler / Mykrobe Coll-Napier barcode for MTBC, Pangolin + Nextclade for SARS-CoV-2, PopPUNK GPSC for S. pneumoniae). Use when typing bacterial isolates for surveillance or outbreak investigation, choosing between cgMLST allele distance and core-SNP distance for cluster definition, harmonising calls across schemas / database versions (chewBBACA vs Ridom vs EnteroBase), assigning MTBC lineage with the Napier 2020 90-SNP barcode, calling Salmonella serovar via SISTR with monophasic Typhimurium awareness, running Pangolin UShER mode with explicit pangolin-data version pinning, or selecting a typing resolution to match the surveillance question.

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Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs. Use when orthologs are already curated upstream, when the question is "what is the X ortholog of Y" rather than "how to infer orthology de novo", when batch-mapping gene IDs across species, or when comparing the resources for consensus calls. Encodes confidence-level semantics, 1:1 vs 1:many vs many:many, HomoloGene deprecation, and when to defect to de novo computation.

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Retrieve records from NCBI databases using Biopython Bio.Entrez (EFetch, ESummary). Use when downloading sequences, fetching GenBank/GenPept records, getting document summaries, parsing nested XML, navigating GI deprecation, choosing between rettype+retmode combinations, and parsing into Biopython SeqRecord/SwissProt objects. Covers nucleotide, protein, gene, pubmed, sra, gds, taxonomy, snp, clinvar.

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