「rest」の検索結果

Retrieve protein sequences, annotation, and structures from UniProtKB, the RCSB PDB, and AlphaFold DB. Use this skill to resolve a gene or protein name to a UniProt accession, pull sequences and FASTA files, find binding sites and domains, search the PDB by UniProt accession, sequence, ligand, or text, download mmCIF/PDB coordinates and biological assemblies, fetch AlphaFold models with their pLDDT confidence, and check whether a structure is actually usable before docking or simulating it. Also trigger on UniProt accessions, PDB ids, rest.uniprot.org, search.rcsb.org, files.rcsb.org, alphafold.ebi.ac.uk, id mapping, SEQRES, or missing residues.

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Search the ClinicalTrials.gov registry through its version 2 REST API for interventional and observational studies, their phases, enrolment, endpoints, sponsors, and posted results. Use this skill to survey who is developing what against an indication, date a competitor's programme, read primary and secondary outcome measures, find eligibility criteria, and distinguish a study that completed from one that was terminated or withdrawn. Also trigger on ClinicalTrials.gov, NCT number, trial registry, study phase, enrolment, primary outcome measure, recruiting status, trial sponsor, or competitive landscape.

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Generalised autonomous optimisation loop — soft RLVR for any artifact a user can measure. Web runtime package: uses memory in this order: connector-backed, project-pack, none. Never assumes subprocess access or unrestricted local files. Use this skill whenever a user wants to iteratively improve an artifact — code, prompts, documents, configs, designs, content — by running structured experiments, evaluating results against a multi-dimensional rubric, and learning from each attempt. Triggers include: "optimise this", "keep improving until it's good", "run experiments on", "autoresearch", "iterate on this overnight", "try different approaches and pick the best", or any request implying repeated evaluate-and-improve cycles.

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Resolve merge and rebase conflicts with safe recovery strategies. Covers identifying conflict sources, reading conflict markers, choosing resolution strategies, and continuing or aborting operations safely. Use when a git merge, rebase, cherry-pick, or stash pop reports conflicts, when a git pull results in conflicting changes, or when you need to safely abort and restart a failed merge or rebase operation.

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Apply software pipelining (double-buffering) to a tiled GPU kernel to overlap global memory loads with Tensor Core computation. Covers prologue/loop/epilogue restructuring, LDG-register vs cp.async (LDGSTS) variant selection based on compute/load ratio, shared memory budget verification against architecture-specific occupancy cliffs, and SASS-level verification of load/compute overlap.

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Conduct structured insect behavior observations using sampling protocols, ethogram categories, event recording, interaction logging, environmental context, and summary analysis. Covers focal animal sampling, scan sampling, all-occurrences sampling, and instantaneous sampling methods. Defines a standard insect ethogram with locomotion, feeding, grooming, mating, defense, communication, and rest categories. Includes timestamped event recording, intraspecific and interspecific interaction logging, environmental covariate documentation, and time budget analysis. Use when studying insect behavior for ecological research, documenting behavioral repertoires for a species, observing pollinator activity or predator-prey dynamics, or supporting conservation assessments with behavioral data.

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Implement secure secrets management in Kubernetes using SealedSecrets for GitOps, External Secrets Operator for cloud secret managers, and rotation strategies. Handle TLS certificates, API keys, and credentials with encryption at rest and RBAC controls. Use when storing sensitive configuration for Kubernetes applications, implementing GitOps where secrets must be version-controlled, integrating with AWS Secrets Manager or Azure Key Vault, rotating credentials without downtime, or migrating from plaintext Secrets to encrypted solutions.

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Install and configure the putior R package for workflow visualization. Covers CRAN and GitHub installation, optional dependencies (mcptools, ellmer, shiny, shinyAce, logger, plumber2), and verification of the complete annotation-to-diagram pipeline. Use when setting up putior for the first time, preparing a machine for workflow visualization tasks, when a downstream skill requires putior to be installed, or restoring an environment after an R version upgrade or renv wipe.

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Select an OCR/HTR engine by benchmarking candidates on the same labelled samples — source ground truth from open datasets (e.g. Hugging Face PAGE-XML corpora) or hand-transcription, wrap every engine behind a transcribe(image_path) -> str adapter (vision-LLMs via any OpenAI-compatible endpoint, dedicated HTR REST APIs, cloud OCR), and score with zero-dependency raw CER, lenient CER, WER, and a critical name/date token diff. Use when choosing an engine for handwriting or historical-document transcription, when published accuracy claims need honest verification on your own material, or when a records workflow must surface confident-but-wrong names and dates that a low aggregate CER hides.

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.NET SDK and NuGet tooling conventions: dotnet CLI commands (new/build/run/test/publish/restore/format), NuGet package management (PackageReference, Directory.Packages.props central package management, packages.lock.json), project file conventions (.csproj, .sln, global.json, Directory.Build.props), multi-targeting, and dotnet format. Stack-agnostic — referenced by every .NET plugin in the marketplace. Use this skill to: - Detect the .NET SDK version and run all commands via the dotnet CLI. - Manage NuGet dependencies safely (central package management, no floating versions). - Configure project files and solution-wide properties in Directory.Build.props. - Format code consistently with dotnet format. Do NOT use this skill for: - Framework-specific tooling (dotnet ef migrations, aspnet-codegenerator — those are in aspnet-core-plugin:aspnet-conventions). - Testing patterns — see csharp-foundation:dotnet-testing. - C# language idioms — see csharp-foundation:csharp-conventions.

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Entity Framework Core patterns for ASP.NET Core projects: DbContext design, code-first entity configuration (Fluent API via IEntityTypeConfiguration<T>), relations (HasOne/HasMany, cascade/restrict/set-null), indexes and unique constraints, projection to DTOs (Select + AsNoTracking), avoiding N+1 (Include, AsSplitQuery), transactions, parameterized raw SQL (FromSql with FormattableString), and connection string from IConfiguration. Works alongside aspnet-core-plugin:aspnet-conventions. Use this skill to: - Design a clean DbContext with ApplyConfigurationsFromAssembly for scalable entity registration. - Configure entity properties (column types, max length, precision, nullability) via Fluent API. - Avoid N+1 query problems with explicit Include / projection to DTOs. - Use transactions correctly for multi-entity operations. - Write parameterized raw SQL safely when LINQ is not expressive enough. Do NOT use this skill for: - Migration generation commands (that is efcore-specialist's job in the database extra phase). - ASP.NET Core middleware, DI, or validation — see aspnet-core-plugin:aspnet-conventions. - C# language idioms — see csharp-foundation:csharp-conventions.

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GraphQL, WebSockets, and microservices patterns for NestJS. Apply only when the relevant package is in dependencies (`@nestjs/graphql`, `@nestjs/websockets`, `@nestjs/microservices`). Each section is orientation, not exhaustive — defer to NestJS docs for deep dives. Use this skill to: - Wire a GraphQL resolver (code-first) with class-validator inputs. - Build a WebSocket gateway with auth and room management. - Set up a microservice transport (TCP/RabbitMQ/NATS/Redis/Kafka) and message handlers. Do NOT use this skill for: - REST controllers (see nest-conventions + decorator-patterns). - ORM (see nest-data-layer). - Auth strategies (see security-analyst phase guidance).

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React Native project structure, Expo vs bare workflow detection, app.json/app.config.js patterns, asset handling, fonts, styling approaches, hot-reload-friendly idioms. Use this skill to: - Detect Expo (managed/dev-client/EAS/ejected) vs bare RN workflow. - Pick correct project layout for each workflow. - Configure app.json / app.config.js with bundle ID, splash, icons, deep link schemes. - Handle assets, fonts, images correctly. - Pick a styling approach (StyleSheet / NativeWind / restyle / styled-components). Do NOT use this skill for: - Platform-specific branching (see rn-platform-specific). - Navigation (see rn-navigation). - Storage (see rn-state-and-storage). - Testing (see rn-testing).

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Data fetching, caching, and revalidation patterns in Next.js App Router. Covers native fetch caching, ISR/SSG/SSR per-route choice, generateStaticParams, unstable_cache, revalidatePath/revalidateTag, Route Handlers, dynamic vs static rendering. Use this skill to: - Pick the right rendering mode (SSG / ISR / SSR / streaming) per route. - Use native fetch caching options correctly. - Build Route Handlers that match REST conventions. - Invalidate cached data after mutations. - Use generateStaticParams for dynamic SSG. Do NOT use this skill for: - RSC vs Client boundaries (see server-component-patterns). - Routing primitives (see nextjs-routing). - General conventions (see nextjs-conventions).

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Restate the problem in a distant domain's terms. Use when a problem circles inside its own vocabulary.

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Restate the problem off its forced framing. Use when a framing feels forced and every option inside it loses.

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Use when the user says "wait, what", "the explanation is unclear", "say that again", or asks to restate the last response in plain language. Not for tasks that require source or remote-system changes.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user asks to restore service from a known failure with a prescribed recovery operation. Not for design-time failure definition or open-ended debugging.

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Use when effectful, security-sensitive code needs refinement-typed, SMT-backed verification in F*, in the HACL* or Project Everest style.

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Use when writing or restructuring code, before adding a helper, wrapper, config key, or dependency, or when the user asks for minimal or DRY code. Not for performance tuning: use optimize.

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Use when an implementation has more workarounds than structure and another patch will not pay. Not for in-place re-derivation: use breaking-driven. Not for one-artifact rewrites: use rewrite-clean-v0.

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Fix RFDB V2 graph data silently not persisting to disk after analysis. Use when: (1) rfdb-server reports "0 nodes, 0 edges" on restart despite successful analysis, (2) segment directories exist but are empty (no .bin files), (3) manifest_index.json shows total_nodes: 0 despite analysis logging 70k+ nodes, (4) Docker builds produce empty graph databases, (5) --clear flag used before analyze command. Root cause: GraphEngineV2::clear() replaces the store with MultiShardStore::ephemeral() which has path: None, causing all flush operations to write to in-memory buffers only.

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Handles NoSQL document operations and collection hierarchy exploration. Use for CRUD tasks and data retrieval. Provides flexible document manipulation and structured querying.

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Troubleshoot and resolve common issues with the ClickHouse Node.js client (@clickhouse/client). Use this skill whenever a user reports errors, unexpected behavior, or configuration questions involving the Node.js client specifically - including socket hang-up errors, Keep-Alive problems, stream handling issues, data type mismatches, read-only user restrictions, proxy/TLS setup problems, or long-running query timeouts. Trigger even when the user hasn't precisely named the issue; vague symptoms like "my inserts keep failing" or "connection drops randomly" in a Node.js context are strong signals to use this skill. Do NOT use for browser/Web client issues.

日本語の概要は準備中です。原文の説明を表示しています。