「single」の検索結果

Discover RBP binding motifs from CLIP-seq peaks or single-nucleotide crosslink sites using HOMER, MEME/STREME, kpLogo, mCross (CL-position-registered motifs), PEKA (positional k-mer enrichment), RBPamp (affinity), and RNA Bind-n-Seq (RBNS) cross-validation. Use when characterizing RBP sequence specificity, registering motifs to crosslink positions, validating in vivo CLIP motifs against in vitro RBNS Kd, reconciling motif disagreements across tools, or correcting for the uracil crosslinking bias that contaminates raw CLIP motif logos.

日本語の概要は準備中です。原文の説明を表示しています。

Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.

日本語の概要は準備中です。原文の説明を表示しています。

Generates 3D conformer ensembles using RDKit ETKDGv3 with knowledge-enhanced distance geometry, MMFF94/UFF force-field optimization, CREST + GFN2-xTB semi-empirical refinement, and macrocycle-aware torsion preferences. Provides explicit decision rules for single vs ensemble conformer use, RMSD pruning, energy windows, conformer count, and force-field choice. Use when preparing 3D ligands for docking, generating descriptor input for 3D QSAR, or sampling macrocycle/peptide conformational ensembles.

日本語の概要は準備中です。原文の説明を表示しています。

Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up bioinformatics capabilities or when a bioinformatics task requires specialized skills not yet installed.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze TF motif accessibility variability across samples or single cells using chromVAR. Use when identifying TF motifs whose accessibility correlates with conditions, computing per-sample motif z-scores after matched background correction, comparing to ArchR / Signac equivalents, or distinguishing motif-accessibility signal from per-site footprinting.

日本語の概要は準備中です。原文の説明を表示しています。

Test whether two or more traits share a causal variant at a locus using Bayesian colocalization (coloc.abf, coloc.susie, HyPrColoc, moloc, eCAVIAR, SMR/HEIDI, PWCoCo, SharePro). Use when integrating GWAS with eQTL/sQTL/pQTL/mQTL, distinguishing shared causal variants from LD-driven coincidence, handling allelic heterogeneity, choosing between single-causal vs multi-causal methods, picking PP.H4 thresholds, running sensitivity over p12, or harmonising summary statistics for colocalization.

日本語の概要は準備中です。原文の説明を表示しています。

Read this skill before the first step that uses Claude in Chrome, the browser extension whose tools are named mcp__claude-in-chrome__* (also called Chrome, the browser extension, or the external browser) and which acts in the person's real Chrome with their own sign-ins; before those tools are turned on there may be a single enable__mcp__claude-in-chrome tool instead. It covers loading the tools in one ToolSearch call, checking the person's open tabs and working in a new tab, site permissions, GIF recordings, console logs, dialogs to avoid, and when to stop and ask. It is not for the built-in browser (mcp__Claude_Browser__* or mcp__remote-devices__Claude_Browser__* tools), which has its own skill, and it does not decide which browser to use.

日本語の概要は準備中です。原文の説明を表示しています。

Read this skill before the first step that uses the built-in browser, the browser pane inside the Claude desktop app (also called the in-app browser, the browser pane, Claude's browser, or "your own browser"), whose tools are named mcp__Claude_Browser__* when the session runs in the desktop app and mcp__remote-devices__Claude_Browser__* when a cloud session is linked to the person's computer; before those tools are turned on there may be a single enable__mcp__remote-devices__Claude_Browser tool instead. It covers the pane's persistent sign-ins, tabs and preview_start, reading pages as text, site approvals, what the pane cannot open, and what to do when it cannot be reached. It is not for Claude in Chrome (mcp__claude-in-chrome__* tools), which has its own skill, and it does not decide which browser to use.

日本語の概要は準備中です。原文の説明を表示しています。

Single Source of Truth (SSOT) guidelines for SwiftUI state management. Use when designing state architecture, choosing between @State/@Binding/@StateObject/@ObservedObject/@EnvironmentObject, fixing state synchronization issues, refactoring duplicated state, or reviewing state management in PRs. Covers SSOT principles, property wrapper selection, state lifting, and common violations.

日本語の概要は準備中です。原文の説明を表示しています。

Extract a thesis's dependency fingerprint — the external variables its bull case actually rests on (key customers, suppliers/inputs, technology transitions, macro drivers, single points of failure). Use when user says "dependency map", "what does [TICKER] depend on", "dependency fingerprint", or "map exposures for [TICKER]".

日本語の概要は準備中です。原文の説明を表示しています。

Change conviction level or status on a single thesis. Use when user says "change conviction", "downgrade", "upgrade", "move to monitoring", "close [TICKER]", or "set [TICKER] to [level]".

日本語の概要は準備中です。原文の説明を表示しています。

Download Copernicus CDS ERA5 single-level point time-series climate forcing for non-US or non-NLDAS EcoSIM sites from longitude/latitude coordinates. Use when a paper-derived site is outside the NLDAS domain, lacks AmeriFlux/FLUXNET curated forcing, or needs global ERA5 variables such as 2m temperature, dewpoint temperature, surface pressure, solar radiation, precipitation, and 10m wind components for EcoSIM preprocessing.

日本語の概要は準備中です。原文の説明を表示しています。

A playful, joyful, two-color risograph print aesthetic built on a single warm off-white paper surface running through every section

日本語の概要は準備中です。原文の説明を表示しています。

Warm editorial, print-leaning document design system — parchment background, single ink-blue accent, serif-led hierarchy (LXGW WenKai for Chinese, Charter for English). For résumés, reports, white papers, letters, and editorial reading pages that should feel authored and published. Not a product-UI / component system.

日本語の概要は準備中です。原文の説明を表示しています。

An immersive, interactive, exhibit-style interface that blends storytelling, animation, and gamified elements to create a playful, experience-driven journey. The entire app sits on a single continuous brand-colored canvas (deep green)

日本語の概要は準備中です。原文の説明を表示しています。

A sun-baked, clay-toned editorial interface built on warm cream surfaces, ink-brown headlines set in a display serif, and a single terracotta accent.

日本語の概要は準備中です。原文の説明を表示しています。

Generate a single-file VR-style portfolio website — works are tiled on the inside of a 3D cylinder/sphere (concave wraparound, like an immersive headset), with mouse-controlled head tilt, long-press to drag and browse the infinite canvas, click to open work detail. Includes overlays for About / CV / Contact / Filter. Takes a natural-language description of the studio and works (images + brief copy); outputs ONE working .html file. Runs in BOTH Claude Code (writes to ~/Desktop) and GLM / online chat (outputs HTML inline). Trigger phrases: "做个 VR 作品集", "做个无限画布作品集", "做个穹顶包裹的作品集", "vr-canvas-gen ...", or when user drags this skill folder into chat asking for a wraparound/immersive portfolio site.

日本語の概要は準備中です。原文の説明を表示しています。

Generate a single-file product landing page with a layered ASCII cosmos hero (rotating ASCII planet, drifting irregular asteroids, comet trails, nebula gas clouds — each in its own harmonious color) plus full marketing sections (about / features grid / showcase / spec / pricing / CTA / footer). Takes a natural-language description of one product (any kind — a note app, a coffee subscription, a CLI tool, an indie hardware, a hosting service…) and outputs ONE working .html file with deep-space dark or warm-letterpress theme. Runs in BOTH Claude Code (writes to ~/Desktop) and GLM / online chat (outputs HTML inline). Trigger phrases: "做个宇宙风产品落地页", "生成 ASCII 产品官网", "ascii-cosmos-gen ...", "做个独立软件 / 独立硬件落地页", or when user drags this skill folder into chat asking for an atmospheric product landing page.

日本語の概要は準備中です。原文の説明を表示しています。

Premium pre-launch waitlist page template — dark charcoal canvas with subtle vignette, drifting portrait video-thumbnail cards, fade-up cascades, glass nav, live-updating join counter, single email form with success/error states. Built for creative-tool / AI / niche-SaaS invite-only launches with hushed exclusive tone, not loud growth-marketing.

日本語の概要は準備中です。原文の説明を表示しています。

Generate a single-file industrial-archive product landing page (Nordic museum aesthetic, hash-routed detail pages). Takes a natural-language description of one or more "exhibit-style" products (objects, tools, hardware, watches, kitchenware, lighting, audio, instruments, anything with a designed/forged/restrained quality); outputs ONE working .html file. Visitors see a black-framed cover that flips between exhibits, sidebar index, side meta column (material/origin/year/dimension), and click any exhibit → full detail page (giant italic title, spec table, hero image, lead + 3 prose paragraphs, gallery, prev/next). Runs in BOTH Claude Code (writes to ~/Desktop) and GLM / online chat (outputs HTML inline). Trigger: "做个工业风产品落地页", "做克制之物风格的展品页", "industrial-archive-gen ...", or when user drags this skill folder into chat asking for a product page in the Nordic-industrial archive style.

日本語の概要は準備中です。原文の説明を表示しています。

Hand-drawn paper-wireframe template — white paper background, monochromatic ink palette, SVG turbulence "wobble" filters for pen-quiver authenticity, handwritten fonts (Caveat / Kalam / Ma Shan Zheng / Long Cang), wavy dividers, sketch-rect overlays, marginalia annotations. For PRD illustrations, IA flow docs, low-fidelity layout exploration, "draft / not final" stakeholder communication. Three skeletons (single-page editorial / app multi-screen flow / IA sitemap) — pick one up front based on the artifact, do NOT inherit only the brush strokes.

日本語の概要は準備中です。原文の説明を表示しています。

Generate a single-file Chinese atelier-style portfolio website (horizontal-row list + hover-reveal thumb interaction, art lishu typography "Alimama DaoLiTi" via CDN, light/dark theme, hash-routed detail pages). Takes a natural-language description of the studio (name, director, discipline, works) and outputs ONE working .html file. Runs in BOTH Claude Code (writes to ~/Desktop) and GLM / online chat (outputs HTML inline). Trigger phrases include "做个中式工作室作品集", "做个隶书作品集", "lishu-portfolio-gen ...", "做个白屋风格的作品集", or when user drags this skill folder into chat asking for an atelier-style site.

日本語の概要は準備中です。原文の説明を表示しています。

Launch, inspect, or tear down an isolated fleet of ready SDD Composy tasks: one branch and Git worktree per member, a bound LOOP, cmux/tmux/headless presentation, no automatic merge. Use to run several ready tasks in parallel — 'rodar várias tarefas em paralelo', 'lançar o fleet', 'fleet status', 'tear down member X'. Do NOT use for a single task (sdd-execute, sdd-loop) or for merging without the explicit teardown token.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user wants a PRD exported — 'exportar o PRD', 'gerar o prd.json', 'criar issue com o PRD', 'export PRD to GitHub' — as canonical JSON or as a single GitHub issue. Do NOT use to publish a roadmap with many issues (prd-publish).

日本語の概要は準備中です。原文の説明を表示しています。